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公开(公告)号：US20200000585A1
公开(公告)日：2020-01-02
申请号：US16570780
申请日：2019-09-13
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
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公开(公告)号：US20190099269A1
公开(公告)日：2019-04-04
申请号：US16202967
申请日：2018-11-28
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
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公开(公告)号：US20170056161A1
公开(公告)日：2017-03-02
申请号：US15347505
申请日：2016-11-09
Applicant: Edwards Lifesciences Corporation
Inventor： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Gabriel Iobbi , David J. Evans , Rajesh A. Khanna
IPC: A61F2/24
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9583
Abstract: An assembly for treating a native heart valve can include a prosthetic valve and a delivery apparatus. The prosthetic valve can include an expandable frame, a valve structure, a first end with apertures formed therein, and a second end. The delivery apparatus can include a valve catheter, flexible extension arms, slidable wires, and release members. First ends of the arms can be coupled to a cylindrical coupling element, second ends of the arms can be releasably coupled to the prosthetic valve, and the coupling element can be connected to the distal end of the valve catheter. The slidable wires can extend distally from the distal end of the valve catheter. The release members can be coupled to the distal end of the valve catheter and can extend through a respective aperture of the prosthetic valve, thereby forming a releasable connection between the prosthetic valve and the slidable wires.
Abstract translation: 用于治疗天然心脏瓣膜的组件可以包括人造瓣膜和输送装置。 假体瓣膜可以包括可扩张框架，阀结构，其中形成有孔的第一端和第二端。 输送装置可以包括阀导管，柔性延伸臂，可滑动导线和释放构件。 臂的第一端可以联接到圆柱形联接元件，臂的第二端可以可释放地联接到人工瓣膜，并且联接元件可以连接到瓣膜导管的远端。 滑动导线可以从阀导管的远端向远侧延伸。 释放构件可以联接到瓣膜导管的远端并且可以延伸穿过人造瓣膜的相应孔，从而在假体瓣膜和可滑动线之间形成可释放的连接。
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公开(公告)号：US09539092B2
公开(公告)日：2017-01-10
申请号：US14561113
申请日：2014-12-04
Applicant: Edwards Lifesciences Corporation
Inventor： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario Gabriel Iobbi , David J. Evans , Rajesh A. Khanna
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9583
Abstract: A heart valve delivery system is provided wherein a prosthetic valve is carried on a valve catheter inside a delivery sleeve. A step balloon protrudes from the delivery sleeve and provides a tapered surface for facilitating advancement through a body vessel. The step balloon also aids in crossing the leaflets of a native valve. After the prosthetic valve is positioned within the native valve, the delivery sleeve is retracted to expose the prosthetic valve. If necessary, the step balloon may be expanded to securely seat the prosthetic valve at the site of the native valve. The prosthetic valve is preferably coupled to the valve catheter by a plurality of flexible extension arms which allow the prosthetic valve to be collapsed after initial deployment such that the prosthetic valve may be repositioned if necessary.
Abstract translation: 提供心脏瓣膜输送系统，其中人造瓣膜被携带在输送套筒内的阀导管上。 步进气球从输送套筒突出并提供锥形表面，以便于通过身体血管进入。 阶梯气球还有助于穿过天然瓣膜的小叶。 在人工瓣膜定位在天然瓣膜内之后，输送套筒缩回以露出假体瓣膜。 如果需要，可以扩展踏板气囊以将人工瓣膜牢固地安置在天然瓣膜的位置。 假体瓣膜优选地通过多个柔性延伸臂联接到瓣膜导管，所述多个柔性延伸臂允许假肢瓣膜在初始部署之后被折叠，使得如果必要，可以重新定位假体瓣膜。
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公开(公告)号：US20230165677A1
公开(公告)日：2023-06-01
申请号：US17891928
申请日：2022-08-19
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2475 , A61F2/95 , B05B1/185 , E03C1/066 , E03C1/025 , Y10T29/49863 , A61F2/9522 , A61F2220/005 , A61F2220/0033 , A61F2220/0075 , A61F2230/0054
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
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Patent Agency Ranking
公开(公告)号：US20220211495A1
公开(公告)日：2022-07-07
申请号：US17704660
申请日：2022-03-25
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
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公开(公告)号：US20220110749A1
公开(公告)日：2022-04-14
申请号：US17558322
申请日：2021-12-21
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
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公开(公告)号：US10292817B2
公开(公告)日：2019-05-21
申请号：US16202967
申请日：2018-11-28
Applicant: Edwards Lifesciences Corporation
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
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公开(公告)号：US20180125643A1
公开(公告)日：2018-05-10
申请号：US15833853
申请日：2017-12-06
Applicant: Edwards Lifesciences Corporation
Inventor： Henry Bourang , Thanh Huy Le , David M. Taylor , Sam Sok , Mario M. Gabriel Iobbi , David J. Evans , Rajesh A. Khanna
CPC classification number: A61F2/243 , A61F2/2418 , A61F2/2433 , A61F2/2436 , A61F2/2439 , A61F2002/9517 , A61F2002/9583
Abstract: An assembly for treating a native valve in a human heart includes a prosthetic heart valve having an expandable frame and a valvular structure. The assembly also includes a tubular sleeve and a valve catheter disposed within the sleeve. A plurality of metal extension arms are coupled to the valve catheter for holding the prosthetic heart valve. The extension arms are configured to radially expand with the prosthetic heart valve during expansion of the prosthetic heart valve at a treatment site. A plurality of metal rods extend distally from the valve catheter. The rods are axially movable relative to the extension arms. A plurality of release members are provided for releasing the prosthetic heart valve from the extension arms upon movement of the metal rods.
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公开(公告)号：US20230277310A1
公开(公告)日：2023-09-07
申请号：US18196389
申请日：2023-05-11
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/95 , B05B1/185 , E03C1/025 , E03C1/066 , A61F2/2475 , Y10T29/49863 , A61F2220/0075 , A61F2220/005 , A61F2230/0054 , A61F2/9522 , A61F2220/0033
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment portions and at least three rows of angled struts. The rows include a first row, a second row downstream of the first row, and a third row downstream of the second row. Each row of struts includes angled struts arranged in a zig-zag pattern defining a plurality of crowns. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment portions via sutures extending through apertures in the commissure attachment portions, wherein all of the apertures are located along the length of the frame between a first plane defined by the crowns of the second row of struts and a second plane defined by the crowns of the third row of struts.
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