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公开(公告)号:US20230277310A1
公开(公告)日:2023-09-07
申请号:US18196389
申请日:2023-05-11
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/95 , B05B1/185 , E03C1/025 , E03C1/066 , A61F2/2475 , Y10T29/49863 , A61F2220/0075 , A61F2220/005 , A61F2230/0054 , A61F2/9522 , A61F2220/0033
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment portions and at least three rows of angled struts. The rows include a first row, a second row downstream of the first row, and a third row downstream of the second row. Each row of struts includes angled struts arranged in a zig-zag pattern defining a plurality of crowns. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment portions via sutures extending through apertures in the commissure attachment portions, wherein all of the apertures are located along the length of the frame between a first plane defined by the crowns of the second row of struts and a second plane defined by the crowns of the third row of struts.
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公开(公告)号:US20190091018A1
公开(公告)日:2019-03-28
申请号:US16202980
申请日:2018-11-28
Applicant: Edwards Lifesciences Corporation
Inventor: Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2475 , A61F2/95 , A61F2002/9522 , A61F2220/0033 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , Y10T29/49863
Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
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公开(公告)号:US20170014229A1
公开(公告)日:2017-01-19
申请号:US15209642
申请日:2016-07-13
Applicant: Edwards Lifesciences Corporation
Inventor: Diana Nguyen-Thien-Nhon , Timothy A. Geiser , Larry L. Wood , Dinesh L. Sirimanne , Son Nguyen , Tamir S. Levi , Nikolay Gurovich , Michael Bukin
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2002/072 , A61F2210/0076 , A61F2220/0075 , A61F2230/0026 , A61F2230/0093 , A61F2250/0003 , A61F2250/0039 , A61F2250/0069
Abstract: An implantable prosthetic valve can comprise an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration, the frame defining an axial direction extending from the inflow end to the outflow end, a leaflet structure positioned within the frame and secured thereto, and an annular outer skirt positioned around an outer surface of the frame, wherein the outer skirt comprises an inflow edge secured to the frame at a first location, an outflow edge comprising a plurality of alternating projections and notches, wherein the projections are secured to the frame at a second location, and the notches are not directly secured to the frame, an intermediate portion between the inflow edge and the outflow edge that comprises a plurality of openings.
Abstract translation: 可植入假体瓣膜可以包括环形框架,其包括流入端和流出端,并且在径向折叠构型和径向扩张构型之间径向可折叠并且可扩张,所述框架限定从流入端延伸到流出端的轴向方向, 定位在框架内并固定到其上的小叶结构以及围绕框架的外表面定位的环形外裙部,其中外裙部包括在第一位置处固定到框架的流入边缘,流出边缘包括多个交替 突起和凹口,其中突起在第二位置处固定到框架,并且凹口不直接固定到框架,入口边缘和流出边缘之间的中间部分包括多个开口。
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公开(公告)号:US20150134052A1
公开(公告)日:2015-05-14
申请号:US14483862
申请日:2014-09-11
Applicant: Edwards Lifesciences Corporation
Inventor: Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2475 , A61F2/95 , A61F2002/9522 , A61F2220/0033 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , Y10T29/49863
Abstract: An implantable prosthetic valve, according to one embodiment, comprises a frame, a leaflet structure, and a skirt member. The frame can have a plurality of axial struts interconnected by a plurality of circumferential struts. The leaflet structure comprises a plurality of leaflets (e.g., three leaflets arrange to form a tricuspid valve). The leaflet structure has a scalloped lower edge portion secured to the frame. The skirt member can be disposed between the leaflet structure and the frame.
Abstract translation: 根据一个实施例的可植入人造瓣膜包括框架,小叶结构和裙部构件。 框架可以具有由多个圆周支柱互连的多个轴向支柱。 小叶结构包括多个传单(例如,安排形成三尖瓣的三个小叶)。 小叶结构具有固定到框架的扇形下边缘部分。 裙部构件可以设置在小叶结构和框架之间。
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公开(公告)号:US12064341B2
公开(公告)日:2024-08-20
申请号:US16120112
申请日:2018-08-31
Applicant: Edwards Lifesciences Corporation
Inventor: Lien Huong Thi Hoang , Son V. Nguyen , Hien Tran Ngo , Vivian Tran , Russell T. Joseph , Dinesh L. Sirimanne , Kevin D. Rupp , Diana Nguyen-Thien-Nhon
IPC: A61F2/24
CPC classification number: A61F2/2409 , A61F2/2418 , A61F2230/0006 , A61F2230/0069 , A61F2230/0076
Abstract: A prosthetic heart valve includes an annular frame that has an inflow end and an outflow end and is radially compressible and expandable between a radially compressed configuration and a radially expanded configuration. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame and adapted to seal against surrounding tissue when the prosthetic heart valve is implanted within a native heart valve annulus of a patient. The sealing member can include a mesh layer and pile layer comprising a plurality of pile yarns extending outwardly from the mesh layer.
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公开(公告)号:US20230165677A1
公开(公告)日:2023-06-01
申请号:US17891928
申请日:2022-08-19
Applicant: Edwards Lifesciences Corporation
Inventor: Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2/2475 , A61F2/95 , B05B1/185 , E03C1/066 , E03C1/025 , Y10T29/49863 , A61F2/9522 , A61F2220/005 , A61F2220/0033 , A61F2220/0075 , A61F2230/0054
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
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公开(公告)号:US20220211495A1
公开(公告)日:2022-07-07
申请号:US17704660
申请日:2022-03-25
Applicant: Edwards Lifesciences Corporation
Inventor: Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
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公开(公告)号:US20220110749A1
公开(公告)日:2022-04-14
申请号:US17558322
申请日:2021-12-21
Applicant: Edwards Lifesciences Corporation
Inventor: Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.
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公开(公告)号:US10335271B2
公开(公告)日:2019-07-02
申请号:US15173435
申请日:2016-06-03
Applicant: Edwards Lifesciences Corporation
Inventor: Oanh H. Nguyen , Ivan Jankovic , Diana Nguyen-Thien-Nhon , Juan C. Velez , Jon Boomgarden
IPC: A61F2/24
Abstract: Systems, dies, and methods are provided for processing pericardial tissue. The method includes positioning a die-cut assembly over the pericardial tissue, the die-cut assembly including a die having a plate, a the pattern, and an opening, the die pattern attached to the plate, the opening formed in the plate to provide access to the pericardial tissue, and measuring a thickness of the tissue through the opening. The die-cut assembly may be mounted for automated vertical movement, and a platen on which the tissue is placed is capable of automated horizontal movement. Different target areas on the tissue can be assessed by measuring the thickness through the die, and when an area is deemed suitable the die pattern cuts a shape therefrom. The system is useful for cutting uniform thickness heart valve leaflets, and can be automated to speed up the process.
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公开(公告)号:US10292817B2
公开(公告)日:2019-05-21
申请号:US16202967
申请日:2018-11-28
Applicant: Edwards Lifesciences Corporation
Inventor: Ilia Hariton , Netanel Benichou , Yaacov Nitzan , Bella Felsen , Diana Nguyen-Thien-Nhon , Rajesh A. Khanna , Son V. Nguyen , Tamir S. Levi , Itai Pelled
Abstract: A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.
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