公开(公告)号：US20060138315A1

公开(公告)日：2006-06-29

申请号：US11025233

申请日：2004-12-29

Applicant: John Williams ,  Alexander Ganin ,  Charles Stearns ,  Yiping Shao ,  Floribertus Philippus Martinus Jansen ,  Ravindra Manjeshwar

Inventor： John Williams ,  Alexander Ganin ,  Charles Stearns ,  Yiping Shao ,  Floribertus Philippus Martinus Jansen ,  Ravindra Manjeshwar

IPC: G01T1/164

CPC classification number: G01T1/2985

Abstract: Methods and systems for calibrating a positron emission tomography (PET) system are provided. The method includes determining at least one non-acquisition time period for the PET system. The method further includes automatically acquiring calibration data during the at least one non-acquisition time period.

Abstract translation: 提供了用于校正正电子发射断层摄影（PET）系统的方法和系统。 该方法包括确定PET系统的至少一个非获取时间段。 所述方法还包括在所述至少一个非采集时段期间自动获取校准数据。

公开(公告)号：US20130248719A1

公开(公告)日：2013-09-26

申请号：US13428840

申请日：2012-03-23

Applicant: Lana Volokh ,  Yaron Hefetz ,  Alexander Ganin ,  Ravindra Manjeshwar

Inventor： Lana Volokh ,  Yaron Hefetz ,  Alexander Ganin ,  Ravindra Manjeshwar

IPC: G01T1/164

CPC classification number: A61B6/03 ,  A61B6/037 ,  A61B6/483 ,  A61B6/503 ,  A61B6/52 ,  A61B6/5205 ,  A61B6/5258 ,  A61B2576/023 ,  G06T11/005

Abstract: Systems and methods for attenuation compensation in nuclear medicine imaging based on emission data are provided. One method includes acquiring emission data at a plurality of energy windows for a person having administered thereto a radiopharmaceutical comprising at least one radioactive isotope. The method also includes performing a preliminary reconstruction of the acquired emission data to create one or more preliminary images of a peak energy window and a scatter energy window and determining a body outline of the person from at least one of the reconstructed preliminary image of the peak energy window or of the scatter energy window. The method further includes identifying a heart contour and segmenting at least the left lung. The method additionally includes defining an attenuation map based on the body outline and segmented left lung and reconstructing an image of a region of interest of the person using an iterative joint estimation reconstruction.

Abstract translation: 提供了基于发射数据的核医学成像中衰减补偿的系统和方法。 一种方法包括在给予其的人的多个能量窗口上获取包含至少一种放射性同位素的放射性药物的排放数据。 该方法还包括执行所获取的发射数据的初步重建以创建峰值能量窗口和散射能量窗口的一个或多个初步图像，并且从峰值的重建初步图像中的至少一个中确定人物轮廓线 能量窗或散射能窗。 所述方法还包括识别心脏轮廓并分割至少左肺。 该方法还包括基于身体轮廓和分割的左肺定义衰减图，并且使用迭代联合估计重建来重建人的感兴趣区域的图像。

公开(公告)号：US20070057189A1

公开(公告)日：2007-03-15

申请号：US11226171

申请日：2005-09-14

Applicant: Floribertus Jansen ,  Ravindra Manjeshwar

Inventor： Floribertus Jansen ,  Ravindra Manjeshwar

IPC: G01T1/161

CPC classification number: G01T1/2985

Abstract: A method and system for calibrating a Time of Flight Positron Emission Tomography (TOF PET) system are provided. The method includes storing acquired scan data from detector pairs. The acquired scan data includes image data and timing information. The method further includes reconstructing images using scan data. The method also includes determining a timing correction for each detector based on intensity distribution histograms of emission sources. The system includes a controller, which is configured to perform the above-mentioned method steps.

Abstract translation: 提供了一种用于校准飞行时间正电子发射断层扫描（TOF PET）系统的方法和系统。 该方法包括从检测器对存储获取的扫描数据。 获取的扫描数据包括图像数据和定时信息。 该方法还包括使用扫描数据重建图像。 该方法还包括基于发射源的强度分布直方图确定每个检测器的定时校正。 该系统包括控制器，其被配置为执行上述方法步骤。

公开(公告)号：US20060081784A1

公开(公告)日：2006-04-20

申请号：US10969716

申请日：2004-10-20

Applicant: Steven Ross ,  Charles Stearns ,  Ravindra Manjeshwar

Inventor： Steven Ross ,  Charles Stearns ,  Ravindra Manjeshwar

IPC: G01T1/164

CPC classification number: G06T11/006 ,  G06T2211/424

Abstract: Methods and systems for image overlap correction are provided. The method includes acquiring the emission projection data from a plurality of scan frames that extend across at least a portion of a length of an object being imaged wherein elements of the object lie between a region of overlap between two successive frames. The method further includes iteratively reconstructing a 3D image volume from multi-frame emission projection data by updating an estimate of 3D image volume using emission projection data from the plurality of frames within an iterative reconstruction loop.

Abstract translation: 提供了图像重叠校正的方法和系统。 该方法包括从多个扫描帧中获取发射投影数据，所述多个扫描帧延伸穿过被成像物体的长度的至少一部分，其中物体的元件位于两个连续帧之间的重叠区域之间。 该方法还包括通过使用来自迭代重建循环内的多个帧的发射投影数据更新3D图像体积的估计来从多帧发射投影数据中迭代重建3D图像体积。

公开(公告)号：US20070167697A1

公开(公告)日：2007-07-19

申请号：US11291830

申请日：2005-11-30

Applicant: Ricardo Avila ,  Floribertus Jansen ,  Dinko Trotter ,  James Miller ,  Ravindra Manjeshwar ,  Thomas Sebastian

Inventor： Ricardo Avila ,  Floribertus Jansen ,  Dinko Trotter ,  James Miller ,  Ravindra Manjeshwar ,  Thomas Sebastian

IPC: A61B5/05

CPC classification number: G01T1/1611 ,  A61B6/037 ,  A61B34/10 ,  G01R33/4808 ,  G01R33/481 ,  G01R33/4812 ,  G01R33/4814

Abstract: A malignancy probability is automatically calculated for one or more lesions. The malignancy probability is based on assessments of one or more malignancy characteristics for each lesion derived from two or more structural and/or functional image data sets. Likewise, in some embodiments, the malignancy probability is based on assessments of one or more malignancy characteristics for each lesion derived from a combination of structural and functional image data. In one embodiment, the set of structural image data is a set of CT image data and the set of functional image data is a set of PET image data. The one or more lesions may be detected in the structural and/or functional image data by automated routines or by a visual inspection by a clinician or other reviewer.

Abstract translation: 自动计算一个或多个病变的恶性概率。 恶性概率基于从两个或多个结构和/或功能图像数据集导出的每个病变的一个或多个恶性特征的评估。 类似地，在一些实施例中，恶性概率基于从结构和功能图像数据的组合导出的每个损伤的一个或多个恶性特征的评估。 在一个实施例中，该组结构图像数据是一组CT图像数据，并且功能图像数据集合是一组PET图像数据。 在结构和/或功能图像数据中可以通过自动程序或临床医生或其他审查者的目视检查来检测一个或多个损伤。

公开(公告)号：US20060163485A1

公开(公告)日：2006-07-27

申请号：US11040088

申请日：2005-01-21

Applicant: Charles Stearns ,  Ravindra Manjeshwar

Inventor： Charles Stearns ,  Ravindra Manjeshwar

IPC: G01T1/164

CPC classification number: G01T1/2985

Abstract: A method and system for controlling a positron emission tomography (PET) system is disclosed. The method includes acquiring image data and time-of-flight information from a PET system during an imaging scan. Further, the method includes performing scatter correction on the image data using the time-of-flight information.

Abstract translation: 公开了一种用于控制正电子发射断层摄影（PET）系统的方法和系统。 该方法包括在成像扫描期间从PET系统获取图像数据和飞行时间信息。 此外，该方法包括使用飞行时间信息对图像数据执行散射校正。

公开(公告)号：US20060151705A1

公开(公告)日：2006-07-13

申请号：US11034166

申请日：2005-01-12

Applicant: Ravindra Manjeshwar ,  Floribertus Philippus Martinus Jansen ,  Charles Stearns

Inventor： Ravindra Manjeshwar ,  Floribertus Philippus Martinus Jansen ,  Charles Stearns

IPC: G01T1/164

CPC classification number: G01T1/2985 ,  A61B6/037

Abstract: Methods and systems for providing scatter correction in a positron emission tomography (PET) system are provided. The method includes determining a look-up table of scatter sinograms during a PET acquisition scan period. The method further includes scatter correcting acquired scan data obtained during the PET acquisition scan period.

Abstract translation: 提供了在正电子发射断层摄影（PET）系统中提供散射校正的方法和系统。 该方法包括在PET采集扫描周期期间确定散射正弦图的查找表。 该方法还包括在PET采集扫描周期期间获得的获取的扫描数据的散射校正。

公开(公告)号：US20060145082A1

公开(公告)日：2006-07-06

申请号：US11026236

申请日：2004-12-30

Applicant: Charles Stearns ,  David McDaniel ,  John Williams ,  Alexander Ganin ,  Ravindra Manjeshwar ,  Floribertus Philippus Heukensfeldt Jansen ,  Yiping Shao

Inventor： Charles Stearns ,  David McDaniel ,  John Williams ,  Alexander Ganin ,  Ravindra Manjeshwar ,  Floribertus Philippus Heukensfeldt Jansen ,  Yiping Shao

IPC: G01T1/164

CPC classification number: G01T1/2985

Abstract: Methods and systems for controlling a positron emission tomography (PET) system are provided. The method includes receiving timing information from a PET system during an imaging scan using the PET system. The method further includes processing the received timing information and timing bias information relating to the PET system to control the PET system.

Abstract translation: 提供了用于控制正电子发射断层摄影（PET）系统的方法和系统。 该方法包括在使用PET系统的成像扫描期间从PET系统接收定时信息。 该方法还包括处理接收到的定时信息和与PET系统有关的定时偏差信息以控制PET系统。

公开(公告)号：US20060097175A1

公开(公告)日：2006-05-11

申请号：US10985752

申请日：2004-11-10

Applicant: Alexander Ganin ,  Floribertus Philippus Martinus Jansen ,  Ricardo Avila ,  Dinko Eduardo Trotter ,  Ravindra Manjeshwar ,  James Miller ,  Thomas Sebastian

Inventor： Alexander Ganin ,  Floribertus Philippus Martinus Jansen ,  Ricardo Avila ,  Dinko Eduardo Trotter ,  Ravindra Manjeshwar ,  James Miller ,  Thomas Sebastian

IPC: G01T1/164

CPC classification number: G01T1/2985 ,  A61B6/037 ,  G01T1/1611 ,  G01T1/1615

Abstract: Methods and systems for imaging a patient are provided. The method includes determining a location of a volume of interest within the patient and acquiring a plurality of frames of emission data, at least one frame including the volume of interest. The method further includes determining a time-of-flight (TOF) information of at least a portion of the annihilations detected along a line of response between corresponding coincidence detectors and generating an image of the patient from the emission data using the determined TOF information.