Method, arrangement, and software for optimizing the image quality of movable subjects imaged with a microscope
    14.
    发明授权
    Method, arrangement, and software for optimizing the image quality of movable subjects imaged with a microscope 有权
    用显微镜成像的移动物体的图像质量优化方法,布置和软件

    公开(公告)号:US08014624B2

    公开(公告)日:2011-09-06

    申请号:US10632499

    申请日:2003-08-01

    Inventor: Frank Olschewski

    Abstract: A method and an arrangement for optimizing the image quality of movable subjects imaged with a microscope system are proposed. The microscope system encompasses at least one objective that defines an image window. Motions of the subjects being observed are captured in the image frame. A computer system, having a means for determining a respective displacement vector field from a comparison of the respective pixels of two chronologically successive images, generates a trajectory from the synopsis of the displacement vector field of all the acquired images. A means for applying an operation to the image data along a trajectory is also provided.

    Abstract translation: 提出了一种用于优化用显微镜系统成像的可移动物体的图像质量的方法和装置。 显微镜系统包含至少一个定义图像窗口的物镜。 所观察的被摄体的运动被捕获在图像帧中。 具有用于根据两个按时间顺序连续的图像的各个像素的比较来确定相应的位移矢量场的装置的计算机系统从所有获取的图像的位移矢量场的概要生成轨迹。 还提供了用于沿着轨迹对图像数据应用操作的装置。

    Method for self-monitoring a microscope system, microscope system, and software for self-monitoring a microscope system
    15.
    发明授权
    Method for self-monitoring a microscope system, microscope system, and software for self-monitoring a microscope system 有权
    用于自我监测显微镜系统,显微镜系统和用于自我监测显微镜系统的软件的方法

    公开(公告)号:US07649682B2

    公开(公告)日:2010-01-19

    申请号:US10499216

    申请日:2002-12-09

    Inventor: Frank Olschewski

    CPC classification number: G02B21/365 G06T7/0002

    Abstract: This invention comprises a method, a software, and a microscope system for monitoring and controlling information loss. The observation of information that is not present and the comparison of ideal loss to actual loss generates an explanatory component by means of a rule set. The user is instructed by the microscope system in an appropriate manner, for example by means of a display, to undertake actions that remove the defects.

    Abstract translation: 本发明包括用于监测和控制信息丢失的方法,软件和显微镜系统。 不存在的信息的观察以及理想损失与实际损失的比较通过规则集产生说明性组件。 由显微镜系统以适当的方式(例如通过显示器)指示使用者进行消除缺陷的动作。

    Method; microscope system and software program for the observation of dynamic processes
    17.
    发明授权
    Method; microscope system and software program for the observation of dynamic processes 有权
    方法; 显微镜系统和软件程序,用于观察动态过程

    公开(公告)号:US07120281B2

    公开(公告)日:2006-10-10

    申请号:US10222037

    申请日:2002-08-16

    CPC classification number: G06T9/004 G02B21/367 G06K9/00127 G06T7/20

    Abstract: A microscope system (4) for the observation of dynamic processes comprises a microscope (50) having at least one detector (19), and a computer (34). A buffer memory (54) precedes a comparator (58) that compares image contents of at least two successive image frames (56k and 56k+1). Depending on the result obtained from the comparator (58), the image frames are stored in different segments of a data structure (66) that is provided.

    Abstract translation: 用于观察动态过程的显微镜系统(4)包括具有至少一个检测器(19)的显微镜(50)和计算机(34)。 缓冲存储器(54)位于比较器(58)之前,该比较器比较了至少两个连续的图像帧(56< k>和56< k + 1>)的图像内容。 根据从比较器(58)获得的结果,将图像帧存储在提供的数据结构(66)的不同段中。

    Method for separating fluorescence spectra of dyes present in a sample
    18.
    发明申请
    Method for separating fluorescence spectra of dyes present in a sample 有权
    用于分离样品中存在的染料的荧光光谱的方法

    公开(公告)号:US20050046836A1

    公开(公告)日:2005-03-03

    申请号:US10924422

    申请日:2004-08-24

    Inventor: Frank Olschewski

    Abstract: A system and a method for setting a fluorescence spectrum measurement system for microscopy is disclosed. Using illuminating light (3) from at least one laser that emits light of one wavelength, a continuous wavelength region is generated. Dyes are stored, with the pertinent excitation and emission spectra, in a database of a computer system (23). For each dye present in the specimen (15), a band of the illuminating light (3) and a band of the detected light (17) are calculated, the excitation and emission spectra read out from the database being employed. Setting of the calculated band in the illuminating light and in the detected band [sic] is performed on the basis of the calculation. Lastly, data acquisition is accomplished with the spectral microscope (100).

    Abstract translation: 公开了一种用于设置用于显微镜的荧光光谱测量系统的系统和方法。 使用来自发射一个波长的光的至少一个激光器的照明光(3),产生连续的波长区域。 将染料与相关的激发和发射光谱一起存储在计算机系统(23)的数据库中。 对于样品(15)中存在的每种染料,计算照明光(3)的带和检测光(17)的带,从采用数据库读出的激发和发射光谱。 在计算的基础上进行照明光和检测波段的计算频带的设定。 最后,用光谱显微镜(100)完成数据采集。

    Method for separating fluorescence spectra of dyes present in a sample
    19.
    发明授权
    Method for separating fluorescence spectra of dyes present in a sample 有权
    用于分离样品中存在的染料的荧光光谱的方法

    公开(公告)号:US07319520B2

    公开(公告)日:2008-01-15

    申请号:US10924422

    申请日:2004-08-24

    Inventor: Frank Olschewski

    Abstract: A system and a method for setting a fluorescence spectrum measurement system for microscopy is disclosed. Using illuminating light (3) from at least one laser that emits light of one wavelength, a continuous wavelength region is generated. Dyes are stored, with the pertinent excitation and emission spectra, in a database of a computer system (23). For each dye present in the specimen (15), a band of the illuminating light (3) and a band of the detected light (17) are calculated, the excitation and emission spectra read out from the database being employed. Setting of the calculated band in the illuminating light and in the detected light is performed on the basis of the calculation. Lastly, data acquisition is accomplished with the spectral microscope (100).

    Abstract translation: 公开了一种用于设置用于显微镜的荧光光谱测量系统的系统和方法。 使用来自发射一个波长的光的至少一个激光器的照明光(3),产生连续的波长区域。 将染料与相关的激发和发射光谱一起存储在计算机系统(23)的数据库中。 对于样品(15)中存在的每种染料,计算照明光(3)的带和检测光(17)的带,从采用数据库读出的激发和发射光谱。 在计算的基础上进行照明光和检测光中的计算频带的设定。 最后,用光谱显微镜(100)完成数据采集。

    Method for user training for a scanning microscope, scanning microscope, and software program for user training for a scanning microscope
    20.
    发明授权
    Method for user training for a scanning microscope, scanning microscope, and software program for user training for a scanning microscope 有权
    用于扫描显微镜,扫描显微镜和用于培养扫描显微镜的软件程序的用户培训方法

    公开(公告)号:US07218762B2

    公开(公告)日:2007-05-15

    申请号:US10369960

    申请日:2003-02-18

    Inventor: Frank Olschewski

    CPC classification number: G02B21/002

    Abstract: A method for user training for a scanning microscope makes possible rapid setting of a scanning microscope with little specimen impact. It is possible to acquire an entire spectrum of a specimen. This specimen can be retrieved from the memory of the computer system for training purposes. The user can then make changes in the setting capabilities displayed to him on the user interface and assess the result thereof, also on the user interface. This can be done without time pressure until the user is satisfied with the result displayed on the user interface.

    Abstract translation: 用于扫描显微镜的用户培训的方法使得可以快速设置具有少量样品冲击的扫描显微镜。 可以获取样本的整个谱图。 可以从计算机系统的存储器中检索该样本用于训练目的。 然后,用户可以在用户界面上对他显示的设置功能进行更改,并在用户界面上评估其结果。 这可以毫无时间地完成,直到用户对用户界面上显示的结果满意为止。

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