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公开(公告)号:US20080070884A1
公开(公告)日:2008-03-20
申请号:US11800495
申请日:2007-05-04
申请人: Franz Von Nussbaum , Nina Brunner , Chantal Fuerstner , Rainer Endermann , Jacques Ragot , Joachim Telser , Werner Schroeder , Sonja Anlauf , Joachim Schuhmacher , Elke Hartmann
发明人: Franz Von Nussbaum , Nina Brunner , Chantal Fuerstner , Rainer Endermann , Jacques Ragot , Joachim Telser , Werner Schroeder , Sonja Anlauf , Joachim Schuhmacher , Elke Hartmann
IPC分类号: A61K31/33 , A61P43/00 , C07D245/00
CPC分类号: C07K7/56
摘要: The invention relates to cyclic nonapeptide amides and to methods for their preparation and to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infectious diseases.
摘要翻译: 本发明涉及环状非肽肽酰胺及其制备方法及其用于生产用于治疗和/或预防疾病,特别是细菌感染性疾病的药物。
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公开(公告)号:US07718611B2
公开(公告)日:2010-05-18
申请号:US11800495
申请日:2007-05-04
申请人: Franz Von Nussbaum , Nina Brunner , Chantal Fuerstner , Rainer Endermann , Jacques Ragot , Joachim Telser , Werner Schroeder , Sonja Anlauf , Joachim Schuhmacher , Elke Hartmann
发明人: Franz Von Nussbaum , Nina Brunner , Chantal Fuerstner , Rainer Endermann , Jacques Ragot , Joachim Telser , Werner Schroeder , Sonja Anlauf , Joachim Schuhmacher , Elke Hartmann
CPC分类号: C07K7/56
摘要: The invention relates to cyclic nonapeptide amides and to methods for their preparation and to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infectious diseases.
摘要翻译: 本发明涉及环状非肽肽酰胺及其制备方法及其用于生产用于治疗和/或预防疾病,特别是细菌感染性疾病的药物。
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公开(公告)号:US20060264358A1
公开(公告)日:2006-11-23
申请号:US11267063
申请日:2005-11-04
申请人: Franz Nussbaum , Nina Brunner , Rainer Endermann , Chantal Furstner , Elke Hartmann , Holger Paulsen , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruning
发明人: Franz Nussbaum , Nina Brunner , Rainer Endermann , Chantal Furstner , Elke Hartmann , Holger Paulsen , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruning
CPC分类号: C07K7/06
摘要: The invention relates to nonadepsipeptides and processes for their preparation, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
摘要翻译: 本发明涉及非肽缩肽及其制备方法,以及它们用于生产药物用于治疗和/或预防疾病,特别是细菌感染性疾病的用途。
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公开(公告)号:US20090105119A1
公开(公告)日:2009-04-23
申请号:US12180507
申请日:2008-07-25
申请人: Franz VON NUSSBAUM , Nina Brunner , Rainer Endermann , Joachim Telser , Joachim Schuhmacher , Sonja Anlauf
发明人: Franz VON NUSSBAUM , Nina Brunner , Rainer Endermann , Joachim Telser , Joachim Schuhmacher , Sonja Anlauf
CPC分类号: C07K11/02
摘要: The invention relates to nonadepsipeptides and methods for their preparation, as well as to their use for manufacturing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
摘要翻译: 本发明涉及非吸收肽及其制备方法,以及它们用于制备用于治疗和/或预防疾病,特别是细菌感染性疾病的药物的用途。
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公开(公告)号:US20050256037A1
公开(公告)日:2005-11-17
申请号:US10957489
申请日:2004-10-01
申请人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Hein-Peter Kroll , Franz Von Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand
发明人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Hein-Peter Kroll , Franz Von Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand
CPC分类号: C07K5/0812 , A61K38/00
摘要: The invention relates to antibacterial amide macrocycles and process for their preparation, their use for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially of bacterial infections.
摘要翻译: 本发明涉及抗菌酰胺大环化合物及其制备方法,其用于治疗和/或预防疾病的用途及其用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US20060258571A1
公开(公告)日:2006-11-16
申请号:US10522667
申请日:2003-07-18
申请人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Hein-Peter Kroll , Franz Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand
发明人: Thomas Lampe , Isabelle Adelt , Dieter Beyer , Nina Brunner , Rainer Endermann , Kerstin Ehlert , Hein-Peter Kroll , Franz Nussbaum , Siegfried Raddatz , Joachim Rudolph , Guido Schiffer , Andreas Schumacher , Yolanda Cancho-Grande , Martin Michels , Stefan Weigand
IPC分类号: A61K38/12 , A61K31/395 , C07K5/12
CPC分类号: C07K5/0812 , A61K38/00
摘要: The invention relates to antibacterial ester macrocycles of formula (I), methods for the production thereof, and the use thereof for producing medicaments used for the treatment and/or prophylaxis of diseases, particularly bacterial infections.
摘要翻译: 本发明涉及式(I)的抗菌酯大环化合物,其制备方法及其用于制备用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US07446102B2
公开(公告)日:2008-11-04
申请号:US11690762
申请日:2007-03-23
申请人: Rainer Endermann , Kerstin Ehlert , Christoph Freiberg , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Joachim Schuhmacher , Stefan Weigand
发明人: Rainer Endermann , Kerstin Ehlert , Christoph Freiberg , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Joachim Schuhmacher , Stefan Weigand
CPC分类号: C07K7/06 , A61K38/00 , C07K5/0812 , C07K5/1016 , Y02A50/475 , Y02A50/481
摘要: The invention relates to antibacterial amide macrocycles and processes for their preparation, their use for the treatment and/or prophylaxis of diseases and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infections.
摘要翻译: 本发明涉及抗菌酰胺大环化合物及其制备方法,它们用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US20080076745A1
公开(公告)日:2008-03-27
申请号:US11690762
申请日:2007-03-23
申请人: Rainer Endermann , Kerstin Ehlert , Christoph Freiberg , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Joachim Schuhmacher , Stefan Weigand
发明人: Rainer Endermann , Kerstin Ehlert , Christoph Freiberg , Siegfried Raddatz , Martin Michels , Yolanda Cancho-Grande , Joachim Schuhmacher , Stefan Weigand
IPC分类号: C07D245/04 , A61K31/395 , A61P31/04
CPC分类号: C07K7/06 , A61K38/00 , C07K5/0812 , C07K5/1016 , Y02A50/475 , Y02A50/481
摘要: The invention relates to antibacterial amide macrocycles and processes for their preparation, their use for the treatment and/or prophylaxis of diseases and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially bacterial infections.
摘要翻译: 本发明涉及抗菌酰胺大环化合物及其制备方法,它们用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病,特别是细菌感染的药物的用途。
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公开(公告)号:US07402683B2
公开(公告)日:2008-07-22
申请号:US10512724
申请日:2003-04-14
申请人: Nina Brunner , Christoph Freiberg , Thomas Lampe , Ben Newton , Michael Otteneder , Josef Pernerstorfer , Jens Pohlmann , Guido Schiffer , Mitsuyuki Shimada , Niels Svenstrup , Rainer Endermann , Peter Nell
发明人: Nina Brunner , Christoph Freiberg , Thomas Lampe , Ben Newton , Michael Otteneder , Josef Pernerstorfer , Jens Pohlmann , Guido Schiffer , Mitsuyuki Shimada , Niels Svenstrup , Rainer Endermann , Peter Nell
IPC分类号: C07D207/00 , C07D215/38 , C07D213/00 , C07D403/02 , C07D231/00 , A01N43/36 , A01N43/56 , A01N43/40 , A01N43/42
CPC分类号: C07D207/40 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12
摘要: The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection.
摘要翻译: 本发明涉及化合物,其制备方法,包含它们的药物组合物,以及它们在人或动物,特别是细菌感染疾病的治疗和/或预防中的用途。
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公开(公告)号:US20090149528A1
公开(公告)日:2009-06-11
申请号:US12217248
申请日:2008-07-02
申请人: Nina Brunner , Christoph Freiberg , Thomas Lampe , Ben Newton , Michael Otteneder , Joseph Pernerstorfer , Jens Pohlmann , Guido Schiffer , Mitsuyuki Shimada , Niels Svenstrup , Rainer Endermann , Peter Nell
发明人: Nina Brunner , Christoph Freiberg , Thomas Lampe , Ben Newton , Michael Otteneder , Joseph Pernerstorfer , Jens Pohlmann , Guido Schiffer , Mitsuyuki Shimada , Niels Svenstrup , Rainer Endermann , Peter Nell
IPC分类号: A61K31/4025 , C07D207/333 , A61P31/04
CPC分类号: C07D207/40 , C07D401/12 , C07D403/12 , C07D405/12 , C07D405/14 , C07D409/12
摘要: The present invention relates to compounds, to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection.
摘要翻译: 本发明涉及化合物,其制备方法,包含它们的药物组合物,以及它们在人或动物尤其是细菌感染疾病的治疗和/或预防中的用途。
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