公开(公告)号：US20240309028A1

公开(公告)日：2024-09-19

申请号：US18441123

申请日：2024-02-14

Applicant: Gilead Sciences, Inc.

Inventor： Byoung-Kwon Chun ,  Deeba Ensan ,  Rao V. Kalla ,  Devan Naduthambi ,  Dustin S. Siegel

IPC: C07F9/06 ,  A61K31/675

CPC classification number: C07F9/062 ,  A61K31/675

Abstract: Phospholipid compounds and methods of using the same, singly or in combination with additional agents, and pharmaceutical formulations of said compounds for the treatment of viral infections are disclosed.

公开(公告)号：US11780844B2

公开(公告)日：2023-10-10

申请号：US18117858

申请日：2023-03-06

Applicant: Gilead Sciences, Inc.

Inventor： Mark J. Bartlett ,  Daniel H. Byun ,  Yifan Deng ,  Jennifer L. Cosman Ellis ,  Rao V. Kalla ,  Richard L. Mackman ,  Dustin S. Siegel ,  Xianhuang Zeng

IPC: C07D487/04 ,  A61P31/14

CPC classification number: C07D487/04 ,  A61P31/14

Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.

公开(公告)号：US11767337B2

公开(公告)日：2023-09-26

申请号：US17178463

申请日：2021-02-18

Applicant: Gilead Sciences, Inc.

Inventor： Gregory F. Chin ,  Byoung-Kwon Chun ,  Michael O. Clarke ,  Bindu Goyal ,  Hon C. Hui ,  Petr Jansa ,  Richard L. Mackman ,  Dustin S. Siegel ,  Hai Yang

IPC: C07F9/6561 ,  A61P31/14

CPC classification number: C07F9/6561 ,  A61P31/14

Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.

公开(公告)号：US20230295201A1

公开(公告)日：2023-09-21

申请号：US18171950

申请日：2023-02-21

Applicant: Gilead Sciences, Inc.

Inventor： Daniel H. Byun ,  Gregory F. Chin ,  Byoung-kwon Chun ,  Michael O. Clarke ,  Bindu Goyal ,  Hon C. Hui ,  Petr Jansa ,  Richard L. Mackman ,  Michael R. Mish ,  Dustin S. Siegel ,  David Sperandio ,  Hai Yang ,  Lijun Zhang

IPC: C07F9/6561 ,  A61K31/706

CPC classification number: C07F9/6561 ,  A61K31/706

Abstract: The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, and HCV.

公开(公告)号：US20230279013A1

公开(公告)日：2023-09-07

申请号：US18117858

申请日：2023-03-06

Applicant: Gilead Sciences, Inc.

Inventor： Mark J. Bartlett ,  Daniel H. Byun ,  Yifan Deng ,  Jennifer L. Cosman Ellis ,  Rao V. Kalla ,  Richard L. Mackman ,  Dustin S. Siegel ,  Xianhuang Zeng

IPC: C07D487/04 ,  A61P31/14

CPC classification number: C07D487/04 ,  A61P31/14

Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.

公开(公告)号：US20230212199A1

公开(公告)日：2023-07-06

申请号：US17820183

申请日：2022-08-16

Applicant: Gilead Sciences, Inc.

Inventor： Byoung-Kwon Chun ,  Michael O. Clarke ,  Deeba Ensan ,  Rao V. Kalla ,  Richard L. Mackman ,  Jagadeesh N. Manda ,  Devan Naduthambi ,  Dustin S. Siegel

IPC: C07F9/09 ,  A61P31/14

CPC classification number: C07F9/095 ,  A61P31/14

Abstract: Phospholipid compounds and methods of using the same, singly or in combination with additional agents, and pharmaceutical formulations of said compounds for the treatment of viral infections are disclosed.

公开(公告)号：US20230040586A1

公开(公告)日：2023-02-09

申请号：US17355813

申请日：2021-06-23

Applicant: Gilead Sciences, Inc.

Inventor： Daniel H. Byun ,  Byoung-Kwon Chun ,  Michael O. Clarke ,  Petr Jansa ,  Rao V. Kalla ,  Dmitry Koltun ,  Richard L. Mackman ,  Thao D. Perry ,  Dustin S. Siegel ,  Scott P. Simonovich

IPC: C07F9/6561 ,  A61K45/06

Abstract: Compounds and methods of using said compounds, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.

公开(公告)号：US20210284669A1

公开(公告)日：2021-09-16

申请号：US17178156

申请日：2021-02-17

Applicant: Gilead Sciences, Inc.

Inventor： Byoung-Kwon Chun ,  Edward Doerffler ,  Dustin S. Siegel ,  Andrew C. Stevens ,  Tiago Vieira

IPC: C07F9/6561 ,  A61P31/14 ,  A61P31/16 ,  C07D487/04

Abstract: The present disclosure provides a compound of Formula I: which is useful in treating a variety of diseases, such as diseases caused by respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, HCV and/or HBV infections.

公开(公告)号：US20250090537A1

公开(公告)日：2025-03-20

申请号：US18819051

申请日：2024-08-29

Applicant: Gilead Sciences, Inc.

Inventor： Byoung-Kwon Chun ,  Deeba Ensan ,  Dustin S. Siegel

IPC: A61K31/53 ,  A61K9/00 ,  A61P31/14 ,  C07D487/04

Abstract: Antiviral compounds and methods of using the same, singly or in combination with additional agents, and pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.

公开(公告)号：US20250034186A1

公开(公告)日：2025-01-30

申请号：US18755378

申请日：2024-06-26

Applicant: Gilead Sciences, Inc.

Inventor： Byoung-Kwon Chun ,  Edward Doerffler ,  Dustin S. Siegel ,  Andrew C. Stevens ,  Tiago Vieira

IPC: C07F9/6561 ,  A61P31/14 ,  A61P31/16 ,  C07D487/04

Abstract: The present disclosure provides a compound of Formula I: which is useful in treating a variety of diseases, such as diseases caused by respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, HCV and/or HBV infection