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公开(公告)号：US20240174704A1
公开(公告)日：2024-05-30
申请号：US18354362
申请日：2023-07-18
发明人： Gregory F. Chin , Byoung-Kwon Chun , Michael O. Clarke , Bindu Goyal , Hon C. Hui , Petr Jansa , Richard L. Mackman , Dustin S. Siegel , Hai Yang
IPC分类号： C07F9/6561 , A61P31/14
CPC分类号： C07F9/6561 , A61P31/14
摘要： The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
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公开(公告)号：US20220356196A1
公开(公告)日：2022-11-10
申请号：US17176497
申请日：2021-02-16
发明人： Daniel H. Byun , Gregory F. Chin , Byoung-kwon Chun , Michael O. Clarke , Bindu Goyal , Hon C. Hui , Petr Jansa , Richard L. Mackman , Michael R. Mish , Dustin S. Siegel , David Sperandio , Hai Yang , Lijun Zhang
IPC分类号： C07F9/6561
摘要： The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, ebola, Zika, West Nile, Dengue, and HCV.
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公开(公告)号：US20240043427A1
公开(公告)日：2024-02-08
申请号：US17997594
申请日：2021-04-29
发明人： Mark J. Bartlett , Gregory F. Chin , Michael O. Clarke , Jennifer L. Cosman , Deeba Ensan , Bindu Goyal , Stephen Ho , Hon C. Hui , Richard L. Mackman , Michael R. Mish , Scott D. Schroeder , Nathan D. Shapiro , Dustin S. Siegel , Doris T. Tang , Hai Yang
IPC分类号： C07D487/04 , C07D519/00 , A61K45/06 , C07K16/28
CPC分类号： C07D487/04 , C07D519/00 , C07K16/2827 , C07K16/2818 , A61K45/06
摘要： The present disclosure provides pyrimidine dione compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors. The compounds can be used alone or in combination with other anti-cancer agents.
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公开(公告)号：US20230151043A1
公开(公告)日：2023-05-18
申请号：US18098950
申请日：2023-01-19
发明人： Elaine Bunyan , Byoung-Kwon Chun , Kassibla E. Dempah , Hon C. Hui , Rao V. Kalla , Richard L. Mackman
CPC分类号： C07H7/06 , A61P31/12 , C07B2200/13
摘要： Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号：US20220081462A1
公开(公告)日：2022-03-17
申请号：US17458023
申请日：2021-08-26
发明人： Byoung-Kwon Chun , Hon C. Hui , Rao V. Kalla , Richard L. Mackman
摘要： Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号：US12110294B2
公开(公告)日：2024-10-08
申请号：US17243911
申请日：2021-04-29
发明人： Mark J. Bartlett , Gregory F. Chin , Michael O. Clarke , Jennifer L. Cosman , Deeba Ensan , Bindu Goyal , Stephen Ho , Hon C. Hui , Richard L. Mackman , Michael R. Mish , Scott D. Schroeder , Nathan D. Shapiro , Dustin S. Siegel , Doris T. Tang , Hai Yang
IPC分类号： C07D487/04 , A61K45/06 , C07D519/00 , C07K16/28
CPC分类号： C07D487/04 , A61K45/06 , C07D519/00 , C07K16/2818 , C07K16/2827
摘要： The present disclosure provides pyrimidine dione compounds of Formula I
and pharmaceutical compositions thereof, for treating cancer, including solid tumors either-used alone or in combination with other anti-cancer agents.-
公开(公告)号：US11926645B2
公开(公告)日：2024-03-12
申请号：US17458023
申请日：2021-08-26
发明人： Elaine Bunyan , Byoung-Kwon Chun , Kassibla E. Dempah , Hon C. Hui , Rao V. Kalla , Richard L. Mackman
CPC分类号： C07H7/06 , A61P31/12 , C07B2200/13
摘要： Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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公开(公告)号：US20230039553A1
公开(公告)日：2023-02-09
申请号：US17243911
申请日：2021-04-29
发明人： Mark J. Bartlett , Gregory F. Chin , Michael O. Clarke , Jennifer L. Cosman , Deeba Ensan , Bindu Goyal , Stephen Ho , Hon C. Hui , Richard L. Mackman , Michael R. Mish , Scott D. Schroeder , Nathan D. Shapiro , Dustin S. Siegel , Doris T. Tang , Hai Yang
IPC分类号： C07D487/04 , C07D519/00 , A61K45/06 , C07K16/28
摘要： The present disclosure provides pyrimidine dione compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors. The compounds can be used alone or in combination with other anti-cancer agents.
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公开(公告)号：US20210284670A1
公开(公告)日：2021-09-16
申请号：US17178463
申请日：2021-02-18
发明人： Gregory F. Chin , Byoung-Kwon Chun , Michael O. Clarke , Bindu Goyal , Hon C. Hui , Petr Jansa , Richard L. Mackman , Dustin S. Siegel , Hai Yang
IPC分类号： C07F9/6561 , A61P31/14
摘要： The present disclosure provides compounds for treating a variety of diseases, such as respiratory syncytial virus (RSV), HRV, hMPV, Ebola, Zika, West Nile, Dengue, and HCV.
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公开(公告)号：US11814406B2
公开(公告)日：2023-11-14
申请号：US18098950
申请日：2023-01-19
发明人： Elaine Bunyan , Byoung-Kwon Chun , Kassibla E. Dempah , Hon C. Hui , Rao V. Kalla , Richard L. Mackman
CPC分类号： C07H7/06 , A61P31/12 , C07B2200/13
摘要： Compounds and methods of using said compounds, singly or in combination with additional agents, and salts, crystalline forms, pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.
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