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    CLOSED-LOOP CONTROL OF CARDIOPROTECTIVE PRE-EXCITATION PACING
    13.
    发明申请
    CLOSED-LOOP CONTROL OF CARDIOPROTECTIVE PRE-EXCITATION PACING 失效
    保护性预激活的闭环控制

    公开(公告)号：US20080234774A1

    公开(公告)日：2008-09-25

    申请号：US11687957

    申请日：2007-03-19

    申请人： Tamara Colette Baynham ,  Quan Ni ,  Shelley Cazares ,  Kevin J. Stalsberg

    发明人： Tamara Colette Baynham ,  Quan Ni ,  Shelley Cazares ,  Kevin J. Stalsberg

    IPC分类号： A61N1/368

    CPC分类号： A61N1/3627 ,  A61N1/36585 ,  A61N1/368 ,  A61N1/3682 ,  A61N1/3684

    摘要： Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing but may also be hazardous. Described herein is a method and system that uses measures of ventricular dyssynchrony or a patient's physiological response to ventricular dyssynchrony to control the delivery of cardioprotective pre-excitation pacing in closed-loop fashion.

    摘要翻译： 心脏保护性预激发起搏可用于以导致同步收缩的方式对起搏脉冲递送的特定心肌区域应力或去应激。 这种异常收缩负责预激励起搏的所需心脏保护作用，但也可能是危险的。 本文描述了一种方法和系统，其使用心室不同步或患者对心室不同步的生理反应的测量来控制以闭环方式递送心脏保护性预激发起搏。

    Method and apparatus for identifying potentially misclassified arrhythmic episodes
    15.
    发明授权
    Method and apparatus for identifying potentially misclassified arrhythmic episodes 有权
    用于识别潜在错误分类的心律失常发作的方法和装置

    公开(公告)号：US07738950B2

    公开(公告)日：2010-06-15

    申请号：US11643221

    申请日：2006-12-21

    申请人： Christopher Dale Johnson ,  Alok Sathaye ,  Shelley Cazares

    发明人： Christopher Dale Johnson ,  Alok Sathaye ,  Shelley Cazares

    IPC分类号： A61B5/04

    CPC分类号： A61B5/7264 ,  A61B5/02405 ,  A61B5/0245 ,  A61B5/04 ,  A61B5/04525 ,  A61B5/0464 ,  A61B5/6846 ,  A61B5/726 ,  A61N1/37247 ,  G06F19/00 ,  G06F19/3481

    摘要： An implantable cardiac device is configured to classify cardiac arrhythmias using a plurality of arrhythmia discrimination algorithms. Data is provided that is associated with a plurality of cardiac arrhythmic episodes for which a cardiac electrical therapy was delivered or withheld by the implantable medical device based on the plurality of arrhythmia discrimination algorithms. A metric for each of the arrhythmic episodes is computed. The metric defines a measure by which the implantable cardiac device properly classified the arrhythmia. Potentially misclassified arrhythmic episodes of the plurality of cardiac arrhythmic episodes for which cardiac electrical therapy was inappropriately delivered or withheld are algorithmically identified using the metric.

    摘要翻译： 可植入心脏装置被配置为使用多个心律失常鉴别算法对心律失常进行分类。 提供了与多个心律失常发作相关联的数据，根据多种心律不齐判别算法，心脏电疗法由可植入医疗装置递送或保留。 计算每个心律失常发作的指标。 该度量定义了可植入心脏装置适当分类心律失常的措施。 使用度量来算法地识别心电图治疗被不适当地递送或禁止的多个心律失调发作的潜在的错误分类的心律失常发作。

    Arrhythmia Discrimination Based on Determination of Rate Dependency
    16.
    发明申请
    Arrhythmia Discrimination Based on Determination of Rate Dependency 审中-公开
    基于速率依赖性确定的心律失常鉴别

    公开(公告)号：US20100121209A1

    公开(公告)日：2010-05-13

    申请号：US12686122

    申请日：2010-01-12

    申请人： Shelley Cazares ,  Jaeho Kim ,  Yayun Lin ,  Carlos Ricci

    发明人： Shelley Cazares ,  Jaeho Kim ,  Yayun Lin ,  Carlos Ricci

    IPC分类号： A61B5/0464

    CPC分类号： A61B5/0464 ,  A61B5/04525 ,  A61B5/7264

    摘要： Cardiac systems and methods provide for discriminating between supraventricular tachyarrhythmia and ventricular tachyarrhythmia based on a determination that the patient's supraventricular rhythm exhibits rate dependency. One approach involves determining if a patient's supraventricular rhythm exhibits rate dependent morphology. If the patient's supraventricular rhythm is determined to exhibit rate dependent morphology, an implantable device classifies a detected tachyarrhythmia episode based on one or more templates selected from a plurality of rate-indexed templates stored in the device. Determining if the supraventricular rhythm exhibits rate dependent morphology may also include determining one or more rates at which the rate dependent morphology occurs.

    摘要翻译： 心脏系统和方法基于确定患者的室上节律表现出速率依赖性，确定了室上性快速性心律失常与室性快速性心律失常之间的区别。 一种方法涉及确定患者的室上节律是否表现出速率依赖性形态。 如果确定患者的室上节律表现出与速率相关的形态，则可植入装置基于从存储在装置中的多个速率索引模板中选择的一个或多个模板来分类检测到的快速性心律失常发作。 确定室性心律显示出速率依赖性形态还可以包括确定发生速率依赖形态的一个或多个速率。

    METHOD AND APPARATUS TO IMPLEMENT MULTIPLE PARAMETER SETS IN AN IMPLANTABLE DEVICE
    17.
    发明申请
    METHOD AND APPARATUS TO IMPLEMENT MULTIPLE PARAMETER SETS IN AN IMPLANTABLE DEVICE 有权
    在可移植设备中实现多个参数集的方法和装置

    公开(公告)号：US20080154323A1

    公开(公告)日：2008-06-26

    申请号：US11614578

    申请日：2006-12-21

    申请人： Alok S. Sathaye ,  Shelley Cazares ,  Andrew P. Kramer

    发明人： Alok S. Sathaye ,  Shelley Cazares ,  Andrew P. Kramer

    IPC分类号： A61N1/37

    CPC分类号： A61N1/37264

    摘要： An implantable cardiac function management device including a programmable controller can be used to include a user-specifiable therapy control parameter set. The therapy control parameter set may then be configured to include at least one therapy control parameter that is user-configurable to automatically switch from a first parameter value to a second parameter value at a time that occurs between separate user programming sessions of the device. Various attributes of physiological measures may allow for refinement of the parameter sets to adapt to changed conditions of the subject. Methods of use are also presented.

    摘要翻译： 包括可编程控制器的可植入心脏功能管理装置可用于包括用户可指定的治疗控制参数组。 治疗控制参数集合然后可被配置为包括用户可配置的至少一个治疗控制参数，以便在设备的不同的用户编程会话之间发生的时刻自动地从第一参数值切换到第二参数值。 生理测量的各种属性可以允许细化参数集以适应被摄体的变化的条件。 还介绍了使用方法。

    Cardiac template generation based on patient response information
    19.
    发明申请
    Cardiac template generation based on patient response information 失效
    基于患者反应信息的心脏模板生成

    公开(公告)号：US20060111747A1

    公开(公告)日：2006-05-25

    申请号：US10995704

    申请日：2004-11-23

    申请人： Shelley Cazares ,  Yayun Lin ,  Alok Sathaye

    发明人： Shelley Cazares ,  Yayun Lin ,  Alok Sathaye

    IPC分类号： A61N1/39

    CPC分类号： A61B5/042 ,  A61N1/3702 ,  A61N1/3925

    摘要： Cardiac treatment methods and devices provide for templates representative of past tachyarrythmia events, each template associated with a therapy. Methods involve providing a cardiac waveform representative of a patient's cardiac activity and identifying a portion that indicates an arrhythmic event. A cardiac template corresponding to the portion is generated, and a therapy is associated with the template useful for treating a subsequent arrhythmia. The waveform portion may be identified by a physician using a patient-external device to display the cardiac waveform. The template may be generated by a physician selecting the cardiac waveform, and determining if the therapy associated with the template was satisfactory and/or effective in treating the arrhythmia. Identification may involve matching the event to templates generated using cardiac waveforms other than the patient's cardiac waveforms. The template may be generated in a patient-internal or patient-external medical device such as a programmer, and/or an advanced patient management system.

    摘要翻译： 心脏治疗方法和装置提供代表过去速发事件的模板，每个模板与治疗相关联。 方法包括提供代表患者心脏活动的心脏波形并识别指示心律失常事件的部分。 产生对应于该部分的心脏模板，并且与可用于治疗随后的心律失常的模板相关联的治疗。 波形部分可以由医师使用患者外部设备来识别，以显示心脏波形。 模板可以由医师选择心脏波形产生，并且确定与模板相关联的治疗是否令人满意和/或有效地治疗心律失常。 识别可能涉及将事件与使用除患者心脏波形之外的心脏波形产生的模板进行匹配。 模板可以在诸如程序员和/或高级患者管理系统的患者内部或患者外部医疗设备中生成。

    Arrhythmia discrimination based on determination of rate dependency
    20.
    发明授权
    Arrhythmia discrimination based on determination of rate dependency 有权
    基于速率依赖性确定的心律失常辨别

    公开(公告)号：US09119547B2

    公开(公告)日：2015-09-01

    申请号：US12686122

    申请日：2010-01-12

    申请人： Shelley Cazares ,  Jaeho Kim ,  Yayun Lin ,  Carlos Alberto Ricci

    发明人： Shelley Cazares ,  Jaeho Kim ,  Yayun Lin ,  Carlos Alberto Ricci

    IPC分类号： A61B5/0464 ,  A61B5/0452 ,  A61B5/00

    CPC分类号： A61B5/0464 ,  A61B5/04525 ,  A61B5/7264

    摘要： Cardiac systems and methods provide for discriminating between supraventricular tachyarrhythmia and ventricular tachyarrhythmia based on a determination that the patient's supraventricular rhythm exhibits rate dependency. One approach involves determining if a patient's supraventricular rhythm exhibits rate dependent morphology. If the patient's supraventricular rhythm is determined to exhibit rate dependent morphology, an implantable device classifies a detected tachyarrhythmia episode based on one or more templates selected from a plurality of rate-indexed templates stored in the device. Determining if the supraventricular rhythm exhibits rate dependent morphology may also include determining one or more rates at which the rate dependent morphology occurs.

    摘要翻译： 心脏系统和方法基于确定患者的室上节律表现出速率依赖性，确定了室上性快速性心律失常与室性快速性心律失常之间的区别。 一种方法涉及确定患者的室上节律是否表现出速率依赖性形态。 如果确定患者的室上节律表现出与速率相关的形态，则可植入装置基于从存储在装置中的多个速率索引模板中选择的一个或多个模板来分类检测到的快速性心律失常发作。 确定室性心律显示出速率依赖性形态还可以包括确定发生速率依赖形态的一个或多个速率。