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111 条记录 (耗时 0.03 秒)

    N-substituted heterocyclic derivatives and preparation thereof
    11.
    发明授权
    N-substituted heterocyclic derivatives and preparation thereof 失效
    N-取代的杂环衍生物及其制备

    公开(公告)号：US4080328A

    公开(公告)日：1978-03-21

    申请号：US484274

    申请日：1974-06-28

    申请人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Izumi Yanagihara ,  Hisao Yamamoto

    发明人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Izumi Yanagihara ,  Hisao Yamamoto

    IPC分类号： C07D401/04

    摘要： Novel N-substituted heterocyclic derivatives represented by the formula, ##STR1## wherein R is hydrogen or lower alkanoyl; R.sub.1 is hydrogen, lower alkyl, lower alkoxy, halogen, nitro, trifluoromethyl, amino or N-lower alkanoylamino; R.sub.2 is hydrogen, halogen, amino or N-lower alkanoylamino; W is oxygen, sulfur, sulfinyl or sulfonyl; and Y is ##STR2## (wherein R.sub.3 is hydrogen, lower alkyl or lower alkanoyl; and R.sub.4 is hydrogen, halogen or lower alkyl), and pharmaceutically acceptable salts thereof, which have excellent anti-inflammatory, analgesic, sedative, anti-convulsive or anti-hypertensive activities.

    摘要翻译： 由下式表示的新型N-取代的杂环衍生物，其中R是氢或低级烷酰基; R 1是氢，低级烷基，低级烷氧基，卤素，硝基，三氟甲基，氨基或N-低级烷酰基氨基; R2是氢，卤素，氨基或N-低级烷酰氨基; W是氧，硫，亚磺酰基或磺酰基; （其中R3为氢，低级烷基或低级烷酰基，R4为氢，卤素或低级烷基）及其药学上可接受的盐，其具有优异的抗炎，止痛，镇静作用 ，抗惊厥或抗高血压活动。

    N-(.omega.-Amino)alkylaniline derivatives
    13.
    发明授权
    N-(.omega.-Amino)alkylaniline derivatives 失效
    N - （{107 - 氨基）烷基苯胺衍生物

    公开(公告)号：US4017624A

    公开(公告)日：1977-04-12

    申请号：US603240

    申请日：1975-08-08

    申请人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Hisao Yamamoto

    发明人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Hisao Yamamoto

    IPC分类号： C07D211/52 ,  C07D295/12 ,  C07D401/04

    CPC分类号： C07D211/52 ,  C07D295/12

    摘要： An N-(.omega.-amino)alkylaniline derivative of the formula: ##STR1## and its pharmaceutically acceptable salts, which are useful as neuroleptic agents and can be prepared by reacting a compound of the formula: ##STR2## with a compound of the formula:H--A[wherein R is hydrogen, C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.7 alkanoyl or aroyl, R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkoxy,A is ##STR3## (wherein R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.7 alkoxy or trifluoromethyl), ##STR4## (wherein R.sub.2 is as defined above and R.sub.3 is hydrogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkanoyl), ##STR5## (wherein R.sub.2 is as defined above or ##STR6## (wherein R.sub.2 and R.sub.3 are each as defined above) and n is 2, 3 or 4].

    摘要翻译： 下式的N-（ω-氨基）烷基苯胺衍生物及其药学上可接受的盐，其可用作抗精神病药，并且可以通过使下式化合物与下式化合物反应来制备：＆lt; IMAGE＆gt; ：

    Preparation of 2-benzoylalkylbenzomorphan
    17.
    发明授权
    Preparation of 2-benzoylalkylbenzomorphan 失效
    2-苯甲酰基烷基苯并咪唑的制备

    公开(公告)号：US3953441A

    公开(公告)日：1976-04-27

    申请号：US150841

    申请日：1971-06-07

    申请人： Toshio Atsumi ,  Kenji Kobayashi ,  Yoshiaki Takebayashi ,  Hisao Yamamoto

    发明人： Toshio Atsumi ,  Kenji Kobayashi ,  Yoshiaki Takebayashi ,  Hisao Yamamoto

    IPC分类号： C07D211/70 ,  C07D221/26

    CPC分类号： C07D221/26 ,  C07D211/70

    摘要： A novel process for preparing 2-benzoylalkylbenzomorphan derivatives and salts thereof, represented by the formula ##SPC1##Wherein n, R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the specification. The process comprises reacting a pyridinium derivative of the formula, ##SPC2##Wherein X is a halogen atom and Y' is an ethylenedioxy group; with a Grignard reagent of the formula, ##SPC3##Wherein R' is a hydrogen atom or a C.sub.1 -C.sub.3 alkoxy group and Z is a halogen atom, to yield a 1,2-dihydropyridine derivative of the formula; ##SPC4##And then reducing the said 1,2-dihydropyridine derivative to give a 1,2,5,6-tetrahydropyridine derivative of the formula, ##SPC5##Wherein Y is an oxygen atom or an ethylenedioxy group, and further cyclizing the obtained 1,2,5,6-tetrahydropyridine derivative.

    摘要翻译： 由式WHEREIN N，R，R1，R2，R3和R4表示的用于制备2-苯甲酰基烷基苯并喃衍生物及其盐的新方法如本说明书中所定义。 该方法包括使下式的吡啶鎓衍生物WHEREIN X是卤素原子，Y'是亚乙二氧基; 与下式的格利雅试剂，其中R'是氢原子或C1-C3烷氧基，Z是卤素原子，得到下式的1,2-二氢吡啶衍生物; 然后减少所得的1,2-二氢吡啶衍生物，得到本发明的1,2,5,6-四氢吡啶衍生物，其中Y是氧原子或亚乙二氧基，进一步环化得到的1,2,5,6-四氢吡啶衍生物， 6-四氢吡啶衍生物。

    Novel 2-propanol derivatives and preparation thereof
    18.
    发明授权
    Novel 2-propanol derivatives and preparation thereof 失效
    新型2-丙醇衍生物及其制备方法

    公开(公告)号：US3951986A

    公开(公告)日：1976-04-20

    申请号：US370693

    申请日：1973-06-18

    申请人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Hisao Yamamoto

    发明人： Isamu Maruyama ,  Masaru Nakao ,  Kikuo Sasajima ,  Shigeho Inaba ,  Hisao Yamamoto

    IPC分类号： C07D211/52 ,  C07D295/092 ,  C07D403/12

    CPC分类号： C07D295/088 ,  C07D211/52 ,  C07D403/12 ,  Y10S514/821

    摘要： 2-Propanol derivatives of the formula: ##SPC1##And their pharmaceutically acceptable acid addition salts, which are useful as medicaments and can be produced by reacting a compound of the formula: A-CH.sub.2 -Z with a compound of the formula: A'-H [wherein R is hydrogen or lower alkanoyl; R.sub.1 is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; W is oxygen, sulfur, sulfinyl or sulfonyl; Y is a group of either one of the formulae: ##SPC2##(wherein R.sub.2 is hydrogen, halogen, lower alkyl or lower alkoxy and R.sub.3 is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl); A and A' are each a group of either one of the formulae: ##SPC3##(wherein R.sub.1, W and Y are each as defined above), provided that A and A' are different each other; and Z is a group of either one of the formulae: ##EQU1## (wherein X is halogen, alkylsulfonyloxy or arylsulfonyloxy and R is as defined above)].

    摘要翻译： 下式的2-丙醇衍生物：

    AUTOMOTIVE INNER CEILING MATERIAL AND MOLDING METHOD THEREOF
    20.
    发明申请
    AUTOMOTIVE INNER CEILING MATERIAL AND MOLDING METHOD THEREOF 审中-公开
    汽车内饰材料及其成型方法

    公开(公告)号：US20110084425A1

    公开(公告)日：2011-04-14

    申请号：US12971720

    申请日：2010-12-17

    申请人： Hisao Yamamoto

    发明人： Hisao Yamamoto

    IPC分类号： B29C43/02 ,  B29C43/52

    CPC分类号： D04H1/74 ,  B60R13/0225 ,  D01D5/34 ,  D01F8/14 ,  D04H1/435 ,  D04H1/4382 ,  D04H1/541 ,  D04H1/55 ,  Y10T442/641

    摘要： The present invention provides an automotive inner ceiling material difficult to deform at a high temperature. Sheath-core type conjugate polyester fibers are prepared. The sheath is a heat fusible component. The core is a non heat fusible component. The sheath is made of copolyester which comprises acid units made of terephthalic acid and diol unites made of ethylene glycol and 1,4-butanediol. The conjugate fibers and the main fibers of polyester are mixed and provided in a card machine to be opened and accumulated to obtain a fibrous web. The fibrous web is heated to melt the sheaths, which are thereafter solidified to bind the fibers to obtain a non woven fabric. The nonwoven fabric is heat-treated at a temperature equal to or higher than the melting point of the sheath. Immediately thereafter, the nonwoven fabric is heat-molded between a pair of a mold plates. During the heat-molding process, the inner temperature is maintained at 100˜130° C. for 60 seconds to obtain the ceiling material.

    摘要翻译： 本发明提供一种难以在高温下变形的汽车内顶板材料。 制备护芯型共轭聚酯纤维。 护套是热熔组件。 核心是非热熔组件。 鞘由共聚酯制成，其包含由对苯二甲酸和由乙二醇和1,4-丁二醇制成的二醇单元制成的酸单元。 将复合纤维和聚酯的主纤维混合并提供在卡片机中以打开和聚集以获得纤维网。 纤维网被加热以熔化护套，然后将其固化以结合纤维以获得无纺织物。 无纺布在等于或高于护套熔点的温度下进行热处理。 此后，立即将非织造布在一对模板之间进行热压成形。 在热成型过程中，将内部温度保持在100〜130℃，持续60秒，得到天花板材料。