-
公开(公告)号:US08426401B2
公开(公告)日:2013-04-23
申请号:US12765018
申请日:2010-04-22
申请人: Haiyan Bian , Kristen Chevalier , Jose Clemente , Pete Connolly , Chris Flores , Shu-Chen Lin , Li Liu , John Mabus , Mark Macielag , Mark McDonnell , Philip Pitis , Yue-Mei Zhang , Sui-Po Zhang , Bin Zhu
发明人: Haiyan Bian , Kristen Chevalier , Jose Clemente , Pete Connolly , Chris Flores , Shu-Chen Lin , Li Liu , John Mabus , Mark Macielag , Mark McDonnell , Philip Pitis , Yue-Mei Zhang , Sui-Po Zhang , Bin Zhu
IPC分类号: A61K31/496 , C07D417/12 , C07D417/14
CPC分类号: C07D403/10 , C07D205/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D491/048 , C07D495/04
摘要: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
-
公开(公告)号:US08362001B2
公开(公告)日:2013-01-29
申请号:US12765487
申请日:2010-04-22
申请人: Haiyan Bian , Kristen Chevalier , Jose Clemente , Pete Connolly , Chris Flores , Shu-Chen Lin , Li Liu , John Mabus , Mark Macielag , Mark McDonnell , Philip Pitis , Yue-Mei Zhang , Sui-Po Zhang , Bin Zhu
发明人: Haiyan Bian , Kristen Chevalier , Jose Clemente , Pete Connolly , Chris Flores , Shu-Chen Lin , Li Liu , John Mabus , Mark Macielag , Mark McDonnell , Philip Pitis , Yue-Mei Zhang , Sui-Po Zhang , Bin Zhu
IPC分类号: A61K31/496 , A61K31/506 , A61K31/517 , C07D295/192 , C07D401/14 , C07D401/06 , C07D403/04 , C07D403/06 , C07D403/10 , C07D409/06 , C07D413/06 , C07D417/06
CPC分类号: C07D403/10 , C07D205/04 , C07D401/10 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/12 , C07D403/14 , C07D405/12 , C07D409/06 , C07D409/12 , C07D409/14 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D491/048 , C07D495/04
摘要: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
-
13.
公开(公告)号:US20120058986A1
公开(公告)日:2012-03-08
申请号:US13224654
申请日:2011-09-02
申请人: Peter J. Connolly , Mark J. Macielag , Bin Zhu
发明人: Peter J. Connolly , Mark J. Macielag , Bin Zhu
IPC分类号: A61K31/427 , A61K31/428 , C07D403/04 , A61K31/397 , C07D409/14 , C07D413/14 , A61K31/423 , C07D403/14 , A61K31/4035 , C07D401/14 , A61K31/454 , C07D513/04 , A61K31/429 , A61P29/00 , A61P1/00 , A61P25/06 , A61P19/02 , A61P21/00 , A61P17/00 , A61P1/02 , A61P17/02 , A61P13/10 , A61P31/00 , A61P11/02 , A61P17/04 , A61P11/00 , A61P1/18 , C07D417/14
CPC分类号: A61K31/397 , A61K31/4035 , A61K31/423 , A61K31/427 , A61K31/428 , A61K31/429 , A61K31/454 , C07D205/04 , C07D403/14 , C07D409/14 , C07D413/14 , C07D417/12 , C07D417/14 , C07D513/04
摘要: Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Q and Z are defined herein.
摘要翻译: 公开了用于治疗各种疾病,综合征,病症和障碍(包括疼痛)的化合物,组合物和方法。 这样的化合物由式(I)表示如下:其中Q和Z在本文中定义。
-
公开(公告)号:US20090299875A1
公开(公告)日:2009-12-03
申请号:US12129701
申请日:2008-05-30
IPC分类号: G06Q30/00
CPC分类号: G06Q30/06 , G06Q30/0601
摘要: A system for facilitating online shopping that includes one or more content providers of a first domain, one or more online merchants of a second domain, and a framework. Web pages may be aggregated from the content providers. Descriptions of products for sale may be aggregated from the online merchants. The products for sale may be matched with the web pages based on relevancy. A list of descriptions of products that are relevant to each web page may be provided. A shopping cart list may be maintained by the framework. The shopping cart list may facilitate payment for the products for sale selected from different web pages.
摘要翻译: 一种用于促进在线购物的系统,其包括第一域的一个或多个内容提供商,第二域的一个或多个在线商家和框架。 可以从内容提供商聚合网页。 可以从在线商家汇总出售产品的描述。 出售的产品可能会根据相关性与网页匹配。 可以提供与每个网页相关的产品的描述的列表。 框架可以维护购物车列表。 购物车列表可以促进从不同网页选择的销售产品的支付。
-
公开(公告)号:US07424112B2
公开(公告)日:2008-09-09
申请号:US11081279
申请日:2005-03-16
申请人: Bin Zhu , Yang Yang , Shipeng Li
发明人: Bin Zhu , Yang Yang , Shipeng Li
IPC分类号: H04L9/00
CPC分类号: H04L9/065 , H04L2209/30 , H04L2209/80
摘要: Systems and methods providing ciphertext switching for syntax compliant encryption are described. In one aspect, intermediate ciphertext is generated from syntax compliant plaintext. Post-processing is applied to the intermediate ciphertext to determine if there are any illegal symbols in the intermediate ciphertext. If an illegal symbol is located, the illegal symbol in the intermediate ciphertext is switched with a corresponding plaintext symbol. One or more iterations of the post-processing and switching operations result in syntax compliant ciphertext.
摘要翻译: 描述了为符合语法的加密提供密文切换的系统和方法。 在一个方面,从语法兼容的明文生成中间密文。 后处理应用于中间密文以确定中间密文中是否存在任何非法符号。 如果存在非法符号,则用相应的明文符号切换中间密文中的非法符号。 后处理和切换操作的一个或多个迭代导致符合语法的密文。
-
公开(公告)号:US20070113096A1
公开(公告)日:2007-05-17
申请号:US11381951
申请日:2006-05-05
申请人: Bin Zhu , Xiaoming Wang , Shipeng Li
发明人: Bin Zhu , Xiaoming Wang , Shipeng Li
IPC分类号: H04L9/00
CPC分类号: H04L67/104 , H04L9/3236 , H04L9/3263 , H04L63/0407 , H04L63/0823 , H04L2209/603 , H04L2209/80
摘要: In a peer-to-peer environment, copyrights and users' privacies can be protected by a tracking mechanism. In described implementations, tracking mechanisms can use certificates that are produced using random numbers to protect the privacy of users and/or certificates that are produced responsive to at least one hardware identifier to enable uploader to be identified to protect copyrights.
摘要翻译: 在对等环境中,版权和用户的隐私可以通过跟踪机制来保护。 在所描述的实现中,跟踪机制可以使用使用随机数产生的证书来保护响应于至少一个硬件标识符产生的用户和/或证书的隐私,以使上载者被识别以保护版权。
-
17.
公开(公告)号:US20050250713A1
公开(公告)日:2005-11-10
申请号:US11114502
申请日:2005-04-26
申请人: Bin Zhu , Brett Marinelli , Mark Macielag
发明人: Bin Zhu , Brett Marinelli , Mark Macielag
IPC分类号: A61K31/7048 , C07H17/00 , C07H17/08
CPC分类号: C07H17/08
摘要: The present invention is directed to novel macrolide antibacterial agents and processes for preparing them. The present invention is further directed to pharmaceutical compositions containing the novel macrolide antibacterial agents disclosed herein and their use in the treatment and prevention of bacterial infections.
摘要翻译: 本发明涉及新型大环内酯类抗菌剂及其制备方法。 本发明进一步涉及含有本文所公开的新型大环内酯抗菌剂及其在治疗和预防细菌感染中的用途的药物组合物。
-
公开(公告)号:US20050080746A1
公开(公告)日:2005-04-14
申请号:US10685234
申请日:2003-10-14
申请人: Bin Zhu , Guofei Gu , Shipeng Li
发明人: Bin Zhu , Guofei Gu , Shipeng Li
IPC分类号: G06F15/00 , G06F21/00 , G06F21/10 , G06F21/62 , G06Q30/06 , G06Q50/10 , G06Q99/00 , G09C1/00 , H04L9/08 , H04L29/08 , G06F17/60
CPC分类号: H04L67/104 , G06F21/10 , G06F2221/0753 , G06F2221/0784 , H04L63/10 , H04L69/329
摘要: A public licensing infrastructure (PLI) for a digital rights management (DRM) system is described. In an implementation, a method includes generating a formal license for content. The formal license includes a decryption key for decrypting the content and access rules for accessing the content. A plurality of license authorities is configured to provide a plurality of partial licenses. The plurality of partial licenses is combinable to form the formal license. Each license authority provides a respective partial license.
摘要翻译: 描述了数字版权管理(DRM)系统的公共许可基础设施(PLI)。 在实现中,一种方法包括生成内容的正式许可证。 正式许可证包括用于解密内容的解密密钥和用于访问内容的访问规则。 多个许可机构被配置为提供多个部分许可证。 多个部分许可证可组合形成正式许可证。 每个许可证机构都提供相应的部分许可证。
-
公开(公告)号:US06226387B1
公开(公告)日:2001-05-01
申请号:US08921931
申请日:1997-08-27
申请人: Ahmed H. Tewfik , Mitchell D. Swanson , Bin Zhu
发明人: Ahmed H. Tewfik , Mitchell D. Swanson , Bin Zhu
IPC分类号: G06K900
CPC分类号: G06T1/0085 , G06T1/0028 , G06T2201/0051 , G06T2201/0052 , G06T2201/0061 , G06T2201/0202 , H04N1/32154 , H04N1/3217 , H04N1/32192 , H04N19/117 , H04N19/132 , H04N19/154 , H04N19/172 , H04N19/176 , H04N19/179 , H04N19/63 , H04N21/23892 , H04N21/8358
摘要: A method and apparatus for the scene-based watermarking of video data is disclosed. In one embodiment, each of a number of frames of a scene of video host data undergoes a temporal wavelet transform, from which blocks are extracted. The blocks undergo perceptual masking in the frequency domain, such that a watermark is embedded therein. Once the watermark block is taken out of the frequency domain, a spatial mask of the original block is weighted to the watermark block, and added to the original block to obtain the watermarked block.
摘要翻译: 公开了一种用于视频数据的基于场景的水印的方法和装置。 在一个实施例中,视频主机数据的场景的多个帧中的每一个经历时间小波变换,从中提取块。 这些块在频域中进行感知掩蔽,使得嵌入水印。 一旦将水印块从频域中取出,将原始块的空间掩码加权到水印块,并将其加到原始块中以获得水印块。
-
公开(公告)号:US10894775B2
公开(公告)日:2021-01-19
申请号:US16341591
申请日:2017-10-09
申请人: Merck Sharp & Dohme Corp. , Michael T. Rudd , Zhaoyang Meng , Jenny Wai , David Jonathan Bennett , Edward J. Brnardic , Nigel J. Liverton , Shawn J. Stachel , Yongxin Han , Paul Tempest , Jiuxiang Zhu , Xuewang Xu , Bin Zhu , Chuanman Huang
发明人: Michael T. Rudd , Zhaoyang Meng , Jenny Wai , David Jonathan Bennett , Edward J. Brnardic , Nigel J. Liverton , Shawn J. Stachel , Yongxin Han , Paul Tempest , Jiuxiang Zhu , Xuewang Xu , Bin Zhu , Chuanman Huang
IPC分类号: C07D221/20 , C07D211/16 , C07D211/96
摘要: In its many embodiments, the present invention provides certain piperidine compounds of the Formula (I): and pharmaceutically acceptable salts thereof, wherein X, Y, R1, R2, R3, L, R4, L1, Q, and R5 are as defined herein. The novel compounds of the invention, and pharmaceutically acceptable compositions comprising a compound thereof, are useful as Liver X-β receptor (LXRβ) agonists, and may be useful for treating or preventing pathologies related thereto. Such pathologies include, but are not limited to, inflammatory diseases and diseases characterized by defects in cholesterol and lipid metabolism, such as Alzheimer's disease.
-
-
-
-
-
-
-
-
-