公开(公告)号：US20240034764A1

公开(公告)日：2024-02-01

申请号：US18266001

申请日：2021-12-10

Applicant: JOINT STOCK COMPANY "BIOCAD"

Inventor： Aleksey Vladimirovich KONONOV ,  Iuliia Viktorovna EVDOKIMOVSKAIA ,  Iana Andreevna SMIRNOVA ,  Stanislav Rudolfovich EVDOKIMOV ,  Elena Sergeevna KOLOSOVA ,  Sergei Andreevich AGEEV ,  Vladimir Sergeevich TSYMPILOV ,  Valery Vladimirovich SOLOVYEV ,  Pavel Andreevich IAKOVLEV ,  Dmitry Valentinovich MOROZOV

IPC: C07K14/54 ,  C12N15/63 ,  A61P35/00 ,  C07K16/28

CPC classification number: C07K14/5428 ,  C12N15/63 ,  A61P35/00 ,  C07K16/2818 ,  C07K2319/30

Abstract: The present invention relates to the field of biotechnology and medicine, in particular to an immunocytokine for activating the human IL-10Rα receptor. The invention further relates to nucleic acids encoding said immunocytokine, expression vectors, host cells and methods for producing same, methods for producing the immunocytokine, pharmaceutical compositions comprising the above immunocytokine, pharmaceutical compositions comprising the above immunocytokine and other therapeutically active compounds, methods for treating an oncological disease and the uses of the immunocytokine or pharmaceutical compositions thereof for treating an oncological disease.

公开(公告)号：US20200291121A1

公开(公告)日：2020-09-17

申请号：US16753488

申请日：2018-10-02

Applicant: JOINT STOCK COMPANY "BIOCAD"

Inventor： Ekaterina Vladimirovna SOFRONOVA ,  Aleksei Konstantinovich MISORIN ,  Aleksandr Nikolaevich DORONIN ,  Timofey Aleksandrovich NEMANKIN ,  Aleksandra Aleksandrovna SOZONOVA ,  Galina Stepanovna ZHIRIVSKAIA ,  Sergey Aleksandrovich LEGOTSKY ,  Anna Konstantinovna VLADIMIROVA ,  Alina Valerevna BELIASNIKOVA ,  Mariia Aleksandrovna SHCHEMELEVA ,  Pavel Andreevich IAKOVLEV ,  Valery Vladimirovich SOLOVYEV ,  Elena Andreevna KRENDELEVA ,  Natalia Evgenevna PESTOVA ,  Dmitry Valentinovich MOROZOV

IPC: C07K16/28 ,  C12N15/64

Abstract: The present invention relates to biotechnology and provides antibodies that specifically bind to IL-5Rα. The invention also relates to DNA encoding said antibodies, the corresponding expression vectors and methods of production thereof, as well as methods of treatment using said antibodies.