摘要:
A translocation-simulating loading apparatus for the gear grinding machine with the shaped grinding wheel is provided. The apparatus includes a load-receiving test piece disposed on the gear grinding machine with the shaped grinding wheel and a load-exerting component for use in loading simulation. The gear grinding machine enables linear movements along the X, Y, and Z axes, a rotary movement around the Y axis, a rotary movement C around the Z axis, and a rotary movement A around the X axis. An angle α is formed between the axis L of a ball seat of the load-exerting component and the X axis direction of a Y axis component and an angle formed between the normal line of a load receiving face a and the X direction of the coordinate system of the machine tool is α. A detection method for static stiffness distribution is provided.
摘要:
The present invention discloses a device for detecting axis coplanarity of orthogonal rotary shafts having a built-in intersection, wherein a front assembly rotary body is coaxially connected on a front assembly housing, the front assembly rotary body and a rear assembly housing are fixedly connected with each other, the rear assembly rotary body is mounted in the rear assembly housing, a first three dimension movement fine tuning mechanism is mounted at an end of the rear assembly rotary body, the first three dimension movement fine tuning mechanism is connected with a standard sphere through a connecting rod, the three dimension movement fine tuning mechanisms are provided in the horizontal direction of the standard sphere and below the standard sphere in vertical direction, and two non-contact displacement sensors are mounted on said two three dimension movement fine tuning mechanisms respectively. The present invention also discloses a precision measurement method for measuring axis coplanarity of the orthogonal rotary shafts having a built-in intersection by using the above device, having a feature of high measurement precision, which is adaptive to coplanarity detections for the cantilever-type orthogonal shafts having a built-in intersection and the clamp-type orthogonal shafts having a built-in intersection.
摘要:
A translocation-simulating loading apparatus for gear grinding machine with shaped grinding wheel is provided. The apparatus comprises a load-receiving test piece (25) disposed on the gear grinding machine with shaped grinding wheel and a load-exerting component for use in loading simulation. The gear grinding machine with shaped grinding wheel enables a linear movement along the X axis, a linear movement forward and backward along the Y axis, a linear movement along the Z axis, a rotary movement n around the Y axis, a rotary movement C around the Z axis, and a rotary movement A around the X axis. An angle α is formed between the axis L of a ball seat (17) of the load-exerting component and the X axis direction of a Y axis component (6); an angle formed between the normal line of a load receiving face a and the X direction of the coordinate system of the machine tool is α. A detection method for static stiffness distribution is provided. The method comprises: moving the load-exerting component to a load-exertion position to exert a load, by means of a coordinating movement in the X, Y, and Z axes; detecting the displacement by a displacement sensor, and detecting the simulated load by a force sensor (13); deriving a stiffness value at the load-exertion position under the simulated load; changing the load-exertion position; repeating the above steps, thus deriving a stiffness distribution under the simulated load. Employment of the load-exerting apparatus enables automatic translocation-simulating loading. The apparatus has a simple structure. Employment of the detection method enables the detection of static stiffness distribution. Operations of the method are simple.
摘要:
The invention provides compositions and methods, e.g., assay technologies and their use in biodetection and diagnostics. More particularly, the invention provides compositions and methods based on nucleic acid-templated chemistry in biodetection and profiling of receptors (and their families) and proteins (and their families), and the use of same in diagnostics.
摘要:
A macro-micro actuated distended guide rail precision rotation apparatus, having a housing of a torque motor and a bearing housing, both fixedly arranged on an upper surface of a base, and a bearing sleeved on the bearing housing. The inner ring of the bearing sleevingly connected to an intermediate rotating body connected to a bearing inner ring cap. A grating is provided at a lower end of the bearing inner ring cap. A connecting piece is arranged on the upper surface of the housing of the torque motor. The lower end of the connecting piece is fixedly connected to a rotary shaft of the torque motor. The connecting piece and the intermediate rotating body are both connected to the lower end of a fine movement mechanism fixedly connected to a rotary worktable. The rotation apparatus allows for highly precise macro-and-micro linked control, and for rotation control of great rotation range.
摘要:
A computer numerical control machine tool for grinding two sides of a plane by shifting self-rotation ultrasonic vibration, wherein a pillar (3) is provided on the tool body (1) of the machine tool, a Y axis movement assembly (12) is provided on the platform of the tool body (1), with a lower revolving movement assembly (11), which revolves about a Z coordinate axis, being mounted on the upper surface of the Y axis movement assembly (12), and a lower grinding plate (10) being mounted coaxially above the lower revolving movement assembly (11); an ultrasonic vibration assembly (2) is mounted fixedly on the pillar (3), with a separation plate (8) for clamping a workpiece assembly (9) being provided on the ultrasonic vibration assembly (2); an X axis movement assembly (4) is mounted on the upper part of the pillar (3), a Z axis movement assembly (5) is mounted on the upright face of the X axis movement assembly (4), with an upper revolving movement assembly (6), which revolves about the Z coordinate axis, being provided on the Z axis movement assembly (5), and an upper grinding plate (7) being mounted coaxially on the revolving axis of the upper revolving movement assembly (6). The present invention enhances the time variation of grinding movement tracks, the uniformity of grinding speed distribution, machining efficiency and machining precision.
摘要:
The invention provides compositions and methods for the detection of biological targets, (e.g. nucleic acids and proteins) by nucleic acid templated chemistry, for example, by generating fluorescent, chemiluminescent and/or chromophoric signals.
摘要:
The invention provides reagents, methods, and compositions for studying protein-protein interactions. The inventive system and methods allow the analysis of protein-protein interactions in vivo and in vitro. Advantages offered by various embodiments of the inventive system and methods compared to existing photocrosslinking approaches include, for example, (i) novel reversible crosslinking reagents that allow easy isolation, purification, and enrichment of the crosslinked products; (ii) trifluoromethyl phenyldiazirine- or perfluorinated phenylazide-based photocrosslinking reagents that provide high specific labeling, no side product, and higher photocrosslinking efficiency; (iii) versatile spacer groups that allow systematic contact site mapping; (iv) novel methods for isolating, purifying, and detecting crosslinked products based on the reversible-link chemistry; and (v) the ability to study the interaction sites in vitro, in situ, or in vivo.
摘要:
The present invention relates compositions and methods that are useful in catalyzing DNA-Programmed Chemistry (or Nucleic Acid-templated chemistry) for use in therapeutic and diagnostic applications.
摘要:
The invention provides compositions and methods for the detection and/or quantification of biological targets (e.g., nucleic acids and proteins) by the nucleic acid-templated creation of one or more reaction products, for example, epitopes, enzyme substrates, enzyme activators, and ligands. The reaction products can be detected and/or quantitated after signal amplification using an amplification system.