-
公开(公告)号：US20160088833A1
公开(公告)日：2016-03-31
申请号：US14946634
申请日：2015-11-19
Applicant: James L. Cook , Clark T. Hung , Eric Lima , Aaron Stoker
Inventor： James L. Cook , Clark T. Hung , Eric Lima , Aaron Stoker
IPC: A01N1/02
CPC classification number: A01N1/0226 , A01N1/021 , A01N1/0242 , A01N1/0263 , A01N1/0284
Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
Abstract translation: 本发明提供了一种用于组织的方法和装置，例如同种异体移植，在无菌组织培养室中在室温下长时间储存和保存。 本发明进一步提供使用如上所述的装置维持组织的无菌的方法。
-
12.发明申请SYSTEMS AND METHODS FOR ALIGNMENT AND SITE PREPARATION OF ROTATOR CUFF GRAFTS 审中-公开ROTATOR CUFF GRAFTS的对准和现场准备的系统和方法公开(公告)号：US20160074151A1
公开(公告)日：2016-03-17
申请号：US14888889
申请日：2014-05-05
Applicant: Ferris M. PFEIFFER , Matthew J. SMITH , James L. COOK , THE CURATORS OF THE UNIVERSITY OF MISSORURI
Inventor： Ferris M. Pfeiffer , Matthew J. Smith , James L. Cook
CPC classification number: A61F2/0805 , A61B17/1633 , A61B17/1684 , A61B17/1714 , A61B17/1778 , A61F2/0811 , A61F2002/087
Abstract: A graft-positioning system that includes a body further comprising a shaft, a handle engaged to the first end of the shaft, a guide rest engaged to the second end of the shaft and a flange engaged to the guide. In addition, the shaft also includes a plurality of pin channels that extend from the first end to the second end of the shaft. The graft-positioning system may also include plurality of guide pins that are configured and arranged to be received within the plurality of pin channels. Additional embodiments provide an arthroscopic cutter that includes a tubular body and a drive shaft attached to a cutting head at one end and situated within a lumen defined within the tubular body. The tubular body further includes a guide rest engaged to the distal end of the tubular body and a flange engaged to the guide rest.
Abstract translation: 一种移植物定位系统，其包括主体，其还包括轴，与所述轴的第一端接合的手柄，接合到所述轴的第二端的引导支架和与所述引导件接合的凸缘。 此外，轴还包括从轴的第一端延伸到第二端的多个销通道。 移植物定位系统还可以包括多个引导引脚，其被配置和布置成被容纳在多个引脚通道内。 另外的实施例提供了一种关节镜切割器，其包括管状主体和驱动轴，驱动轴在一端附接到切割头并且位于管状体内限定的内腔内。 管状体还包括接合到管状主体的远端的引导托架和与导向托架接合的凸缘。
-
13.发明申请OSTEOCHONDRAL IMPLANTS, ARTHROPLASTY METHODS, DEVICES, AND SYSTEMS 审中-公开OSTEOCHONDRAL植入物，ARTHROPLASTY方法，设备和系统公开(公告)号：US20140091491A1
公开(公告)日：2014-04-03
申请号：US14104600
申请日：2013-12-12
Applicant: Clark T. Hung , Gerard A. Ateshian , Eric G. Lima , James L. Cook , Li Ming Bian
Inventor： Clark T. Hung , Gerard A. Ateshian , Eric G. Lima , James L. Cook , Li Ming Bian
CPC classification number: B29C39/003 , A61F2/28 , A61F2/30756 , A61F2002/30762 , A61F2002/30766 , A61F2002/30878 , A61F2002/30948 , A61F2002/30952 , A61F2002/30962 , A61F2310/00131 , A61L27/3817 , A61L27/3852 , A61L27/3895 , A61L27/52 , A61L27/56 , A61L2430/06 , B29C39/10 , C12N5/0655 , C12N2501/15 , C12N2533/76
Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.
Abstract translation: 用于重建或修复生物生物体的一个或多个关节软骨表面的植入物包括固定到工程组织的工程组织和生物相容性多孔基底，用于将植入物附着到生物体的天然骨。 工程组织包括含有生物相容性材料的支架和由支架支撑的多个活的软骨细胞。 提供了用于培养软骨细胞并入生物相容性植入物的方法。 还提供了用于从细胞种植支架产生功能性软骨组织的生物反应器和用于产生功能性软骨组织的系统。
-
公开(公告)号：US20110218116A1
公开(公告)日：2011-09-08
申请号：US13041055
申请日：2011-03-04
Applicant: James L. Cook , Cristi R. Cook , Aaron M. Stoker , Keiichi Kuroki , Bridget Colleen Garner , Richard Evans , Brandon Lee Roller , Prakash Sidha Jayabalan
Inventor： James L. Cook , Cristi R. Cook , Aaron M. Stoker , Keiichi Kuroki , Bridget Colleen Garner , Richard Evans , Brandon Lee Roller , Prakash Sidha Jayabalan
IPC: C40B30/04 , C12Q1/68 , G01N33/53 , G01N33/566 , G01N33/00 , C40B40/10 , G01N27/447 , G01N33/559 , H01J49/26
CPC classification number: G01N33/6887 , C12Q1/6883 , C12Q2600/112 , C12Q2600/136 , G01N33/5308 , G01N2333/52 , G01N2333/5421 , G01N2800/105 , G01N2800/56
Abstract: Biomarkers, biomarker panels and methods for diagnosing osteoarthritis (OA) are disclosed, using measurement of the expression level of certain polypeptides in a test sample from a subject, including MCP1, IL8, KC, MMP2, MMP3, IL6, MMP1, RANTES, MMP9, IL1B, Apolipoprotein A1, Apolipoprotein E, DCN, CILP and COMP. Related methods for monitoring OA treatment efficacy, diagnostic reagents, and kits are also described.
Abstract translation: 公开了用于诊断骨关节炎（OA）的生物标志物，生物标志物组和方法，其使用来自受试者（包括MCP1，IL8，KC，MMP2，MMP3，IL6，MMP1，RANTES，MMP9）的测试样品中某些多肽的表达水平进行测量 ，IL1B，载脂蛋白A1，载脂蛋白E，DCN，CILP和COMP。 还描述了用于监测OA治疗功效，诊断试剂和试剂盒的相关方法。
-
公开(公告)号：US06267276B1
公开(公告)日：2001-07-31
申请号：US09158809
申请日：1998-09-22
Applicant: James L. Cook
Inventor： James L. Cook
IPC: A45F500
CPC classification number: A45F3/02 , A01K97/10 , Y10S224/922
Abstract: A carrier for fishing accessories which can be worn without interfering with the fishing operation, whether standing, sitting, or walking. Broadly, the carrier includes a pouch, carrying mechanism and fishing rod suspension device. The pouch is capable of holding many different types of fishing accessories. The versatile carrying mechanism, such as, an adjustable shoulder strap and waist strap, allows the fisherman to wear the pouch on the hip, back or shoulder, and on either the right side or left side of the body. The fishing rod suspension device supports and suspends the fishing rod from the pouch thereby freeing the fisherman's hands for rigging the line or performing other fishing operations. The carrier may also include a work surface, such as a magnetic plate, to hold fishing accessories such as flies, hooks, lures, weights, and tools.
Abstract translation: 钓鱼配件的承运人，可以穿着而不干扰钓鱼作业，无论是站立，坐着还是步行。 广泛地，载体包括袋，运载机构和钓竿悬挂装置。 该袋能够容纳许多不同类型的钓鱼配件。 多功能携带机构，如可调式肩带和腰带，可让渔夫在臀部，背部或肩部以及身体的右侧或左侧佩戴小袋。 钓鱼竿悬挂装置支撑并悬挂该小袋的钓竿，从而释放渔夫的手来操纵钓鱼线或执行其他钓鱼作业。 载体还可以包括工作表面，例如磁性板，以保持诸如苍蝇，钩子，诱饵，重物和工具的钓鱼配件。
-
Patent Agency Ranking
公开(公告)号：US20140180414A1
公开(公告)日：2014-06-26
申请号：US14102187
申请日：2013-12-10
Applicant: Ferris M. Pfeiffer , Aaron M. Stoker , James L. Cook
Inventor： Ferris M. Pfeiffer , Aaron M. Stoker , James L. Cook
IPC: A61B17/16
CPC classification number: A61B17/1635 , A61B17/16 , A61B17/1604 , A61B17/1613 , A61B17/1615 , A61B17/1622 , A61B17/3417 , A61B17/3439 , B23B51/04 , B23B51/0406 , B23B51/0413 , B23B51/0453 , B23B51/05 , B23B2251/428 , B23B2251/54
Abstract: Systems, apparatus, and methods may be adapted for grafting tissue at a tissue site that may include an elongate housing and a plurality of elongate cutting members. The plurality of elongate cutting members may define a cutting surface at a distal end of the elongate housing. The cutting surface may be adapted to contract from a first diameter to a second diameter that is less than the first diameter. The contraction of the cutting surface from the first diameter to the second diameter may define a tapered profile between the first diameter and the second diameter suitable for obtaining a tapered graft.
Abstract translation: 系统，装置和方法可以适于在组织部位移植组织，所述组织部位可包括细长壳体和多个细长切割构件。 多个细长切割构件可以在细长壳体的远端处限定切割表面。 切割表面可以适于从第一直径收缩到小于第一直径的第二直径。 切割表面从第一直径到第二直径的收缩可以限定适于获得锥形移植物的第一直径和第二直径之间的锥形轮廓。
-
公开(公告)号：US20120177615A1
公开(公告)日：2012-07-12
申请号：US13349534
申请日：2012-01-12
Applicant: James L. Cook , Clark T. Hung , Eric Lima , Aaron Stoker
Inventor： James L. Cook , Clark T. Hung , Eric Lima , Aaron Stoker
CPC classification number: A01N1/0226 , A01N1/021 , A01N1/0242 , A01N1/0263 , A01N1/0284
Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
Abstract translation: 本发明提供了一种用于组织的方法和装置，例如同种异体移植，在无菌组织培养室中在室温下长时间储存和保存。 本发明进一步提供使用如上所述的装置维持组织的不育的方法。
-
18.发明申请OSTEOCHONDRAL IMPLANTS, ARTHROPLASTY METHODS, DEVICES, AND SYSTEMS 有权OSTEOCHONDRAL植入物，ARTHROPLASTY方法，设备和系统公开(公告)号：US20100036492A1
公开(公告)日：2010-02-11
申请号：US12498358
申请日：2009-07-06
Applicant: Clark T. Hung , Gerard A. Ateshian , Eric G. Lima , James L. Cook , Li Ming Bian
Inventor： Clark T. Hung , Gerard A. Ateshian , Eric G. Lima , James L. Cook , Li Ming Bian
CPC classification number: B29C39/003 , A61F2/28 , A61F2/30756 , A61F2002/30762 , A61F2002/30766 , A61F2002/30878 , A61F2002/30948 , A61F2002/30952 , A61F2002/30962 , A61F2310/00131 , A61L27/3817 , A61L27/3852 , A61L27/3895 , A61L27/52 , A61L27/56 , A61L2430/06 , B29C39/10 , C12N5/0655 , C12N2501/15 , C12N2533/76
Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.
Abstract translation: 用于重建或修复生物生物体的一个或多个关节软骨表面的植入物包括固定到工程组织的工程组织和生物相容性多孔基底，用于将植入物附接到生物体的天然骨。 工程组织包括含有生物相容性材料的支架和由支架支撑的多个活的软骨细胞。 提供了用于培养软骨细胞并入生物相容性植入物的方法。 还提供了用于从细胞种植支架产生功能性软骨组织的生物反应器和用于产生功能性软骨组织的系统。
-
公开(公告)号：US20210177435A1
公开(公告)日：2021-06-17
申请号：US17132474
申请日：2020-12-23
Applicant: Ferris M. Pfeiffer , James L. Cook , James P. Stannard
Inventor： Ferris M. Pfeiffer , James L. Cook , James P. Stannard
Abstract: In one embodiment, a cutting guide is disclosed for use in a surgical procedure to removed damaged tissue from a patient and form a recipient site configured and dimensioned to receive a donor graft. The cutting guide includes a first aim that abuts a section of the damaged tissue to be removed, and a second arm including a hole and a slot that receives a cutting implement, the first arm and the slot defining a distance therebetween corresponding to a desired dimension of the recipient site. In another embodiment, a cutting guide is disclosed for use in forming a donor graft from donor tissue. The cutting guide includes a body that receives the donor tissue, and a shaping member that is rotatably secured to the body. The shaping member includes at least one vane that shapes the donor tissue so as to form the donor graft.
-
公开(公告)号：US09220258B2
公开(公告)日：2015-12-29
申请号：US13349534
申请日：2012-01-12
Applicant: James L. Cook , Clark T. Hung , Eric Lima , Aaron Stoker
Inventor： James L. Cook , Clark T. Hung , Eric Lima , Aaron Stoker
CPC classification number: A01N1/0226 , A01N1/021 , A01N1/0242 , A01N1/0263 , A01N1/0284
Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
Abstract translation: 本发明提供了一种用于组织的方法和装置，例如同种异体移植，在无菌组织培养室中在室温下长时间储存和保存。 本发明进一步提供使用如上所述的装置维持组织的无菌的方法。
-
-
-
-
-
-
-
-
-
Search Results
23
records
(took 0.022 seconds)
