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    SEGMENTATION AND IDENTIFICATION OF LAYERED STRUCTURES IN IMAGES
    11.
    发明申请
    SEGMENTATION AND IDENTIFICATION OF LAYERED STRUCTURES IN IMAGES 有权
    图像中层状结构的分割和识别

    公开(公告)号：US20110182517A1

    公开(公告)日：2011-07-28

    申请号：US13010448

    申请日：2011-01-20

    申请人： Sina Farsiu ,  Stephanie J. Chiu ,  Cynthia A. Toth ,  Joseph A. Izatt ,  Xiao T. Li ,  Peter Christopher Nicholas

    发明人： Sina Farsiu ,  Stephanie J. Chiu ,  Cynthia A. Toth ,  Joseph A. Izatt ,  Xiao T. Li ,  Peter Christopher Nicholas

    IPC分类号： G06K9/66

    CPC分类号： G06T7/11 ,  A61B3/0025 ,  A61B3/102 ,  A61B5/0066 ,  A61B5/7203 ,  A61B2576/02 ,  G06K9/34 ,  G06T7/0012 ,  G06T7/162 ,  G06T2207/10004 ,  G06T2207/10101 ,  G06T2207/30041

    摘要： Disclosed herein are systems and method for segmentation and identification of structured features in images. According to an aspect, a method may include representing an image as a graph of nodes connected together by edges. For example, the image may be an ocular image showing layered structures or other features of the retina. The method may also include adding, to the graph, nodes adjacent to nodes along first and second sides of the graph. The added nodes may have edge weights less than the nodes along the first and second sides of the graph. Further, the method may include assigning start and end points to any of the added nodes along the first and second sides, respectively. The method may also include graph cutting between the start and end points for identifying a feature in the image.

    摘要翻译： 这里公开了用于分割和识别图像中的结构化特征的系统和方法。 根据一个方面，一种方法可以包括将图像表示为由边缘连接在一起的节点的图形。 例如，图像可以是显示视网膜的分层结构或其他特征的眼睛图像。 该方法还可以包括向图中添加与图的第一和第二侧相邻的节点相邻的节点。 添加的节点可以具有小于沿图的第一和第二侧的节点的边权重。 此外，该方法可以包括分别将起点和终点分配给沿着第一和第二侧的任何添加的节点。 该方法还可以包括用于识别图像中的特征的开始点和结束点之间的图形切割。

    Interferometers for optical coherence domain reflectometry
    14.
    发明授权
    Interferometers for optical coherence domain reflectometry 有权
    用于光学相干畴反射测量的干涉仪

    公开(公告)号：US07362444B2

    公开(公告)日：2008-04-22

    申请号：US11470079

    申请日：2006-09-05

    申请人： Joseph A. Izatt ,  Andrew M. Rollins

    发明人： Joseph A. Izatt ,  Andrew M. Rollins

    IPC分类号： G01B11/02 ,  G01B9/02

    CPC分类号： G01B9/02091 ,  G01B9/02022 ,  G01B2290/35 ,  G01B2290/70 ,  G01N21/4795

    摘要： An interferometer system includes an optical radiation source, an optical circulator connected between the optical radiation source and a sample location for transmitting optical radiation from the optical radiation source to the sample location, an output of the optical circulator connected to direct optical radiation to an optical detector. Various embodiments of such a system are possible. A method of performing OCDR or OCT imaging of a sample which involves the steps of: (a) producing low coherence optical radiation; (b) directing at least some of the low coherence optical radiation through an optical circulator to the sample; (c) reflecting at least some of the low coherence optical radiation off of the sample; and (d) detecting at least some of the reflected low coherence optical radiation and producing an electrical signal corresponding thereto.

    摘要翻译： 干涉仪系统包括光辐射源，连接在光辐射源和用于将光辐射从光辐射源传送到采样位置的采样位置之间的光循环器，连接到直接光辐射的光循环器的输出到光学 探测器。 这种系统的各种实施例是可能的。 执行样本的OCDR或OCT成像的方法，其包括以下步骤：（a）产生低相干光辐射; （b）将至少一些低相干光辐射通过光循环器引导到样品; （c）反射离开样品的至少一些低相干光辐射; 和（d）检测至少一些反射的低相干光辐射并产生与其对应的电信号。

    Systems and methods for complex conjugate artifact resolved optical coherence tomography
    15.
    发明授权
    Systems and methods for complex conjugate artifact resolved optical coherence tomography 有权
    复杂结合伪影解析光学相干断层扫描的系统和方法

    公开(公告)号：US09279659B2

    公开(公告)日：2016-03-08

    申请号：US13355381

    申请日：2012-01-20

    申请人： Joseph A. Izatt ,  Al-Hafeez Dhalla

    发明人： Joseph A. Izatt ,  Al-Hafeez Dhalla

    IPC分类号： G01B9/02 ,  A61B3/10

    CPC分类号： G01B9/02091 ,  A61B3/102 ,  G01B9/02004 ,  G01B9/0201 ,  G01B9/02078

    摘要： Systems and methods are disclosed for optical coherence tomography (OCT). For example, imaging can use optical phase modulators based on optical delay lines that, in conjunction with a swept-source laser, can be used to achieve heterodyne swept source optical coherence tomography (SSOCT). These techniques resolve the complex conjugate ambiguity in SSOCT, thereby doubling the usable imaging range. This increased imaging range has numerous important clinical applications in ophthalmology, cardiology and radiology, as well as applications in small animal and non-biological imaging. These methods are superior to prior disclosed methods requiring acousto-optic or electro-optic modulators with respect to complexity, efficiency, imaging speed and image quality.

    摘要翻译： 公开了用于光学相干断层摄影（OCT）的系统和方法。 例如，成像可以使用基于光学延迟线的光学相位调制器，其结合扫频激光器可用于实现外差扫描光学相干断层扫描（SSOCT）。 这些技术解决了SSOCT中复杂的共轭歧义，从而使可用成像范围翻倍。 这种增加的成像范围在眼科，心脏病学和放射学以及小动物和非生物成像中的应用具有许多重要的临床应用。 这些方法优于先前公开的在复杂性，效率，成像速度和图像质量方面需要声光或电光调制器的方法。

    Optical coherence tomography (OCT) imaging systems for use in pediatric ophthalmic applications and related methods and computer program products
    18.
    发明授权
    Optical coherence tomography (OCT) imaging systems for use in pediatric ophthalmic applications and related methods and computer program products 有权
    用于儿科眼科应用的光学相干断层扫描（OCT）成像系统以及相关方法和计算机程序产品

    公开(公告)号：US08421855B2

    公开(公告)日：2013-04-16

    申请号：US12428603

    申请日：2009-04-23

    申请人： Eric L. Buckland ,  Robert H. Hart ,  Glenn A. Myers ,  Joseph A. Izatt

    发明人： Eric L. Buckland ,  Robert H. Hart ,  Glenn A. Myers ,  Joseph A. Izatt

    IPC分类号： A61B3/10 ,  A61B3/107 ,  A61B5/00

    CPC分类号： A61B3/102 ,  A61B5/0066 ,  A61B5/0073 ,  G01B9/02054 ,  G01B9/02063 ,  G01B9/02064 ,  G01B9/02091

    摘要： Optical coherence tomography (OCT) imaging systems for imaging an eye are provided including a source having an associated source arm path and a reference arm having an associated reference arm path coupled to the source path, the reference arm path having an associated reference arm path length. A sample having an associated sample arm path coupled to the source arm and reference arm paths is provided. A reference arm path length adjustment module is coupled to the reference arm. The reference arm path length adjustment module is configured to automatically adjust the reference arm path length such that the reference arm path length is based on an eye length of the subject. Related methods and computer program products are also provided.

    摘要翻译： 提供了用于成像眼睛的光学相干断层摄影（OCT）成像系统，包括具有相关联的源臂路径的源和具有耦合到源路径的相关联的参考臂路径的参考臂，参考臂路径具有相关联的参考臂路径长度 。 提供具有耦合到源臂和参考臂路径的相关联的样本臂路径的样本。 参考臂路径长度调节模块耦合到参考臂。 参考臂路径长度调节模块被配置为自动调整参考臂路径长度，使得参考臂路径长度基于被摄体的眼睛长度。 还提供了相关方法和计算机程序产品。

    Methods, systems and computer program products for processing images generated using Fourier domain optical coherence tomography (FDOCT)
    19.
    发明授权
    Methods, systems and computer program products for processing images generated using Fourier domain optical coherence tomography (FDOCT) 有权
    用于处理使用傅立叶域光学相干断层扫描（FDOCT）生成的图像的方法，系统和计算机程序产品

    公开(公告)号：US08401257B2

    公开(公告)日：2013-03-19

    申请号：US12016352

    申请日：2008-01-18

    申请人： Joseph A. Izatt ,  Eric L. Buckland ,  Bennett R. Groshong ,  Bradley A. Bower

    发明人： Joseph A. Izatt ,  Eric L. Buckland ,  Bennett R. Groshong ,  Bradley A. Bower

    IPC分类号： G06K9/20

    CPC分类号： G01B9/02091 ,  A61B3/102 ,  A61B3/117 ,  A61B5/0066 ,  A61B5/7207 ,  A61B5/7257 ,  G01N21/4795 ,  G01P3/36 ,  G06T11/003

    摘要： Methods, systems and computer program products for managing frequency domain optical coherence tomography (FDOCT) image resolution. A spectrum used to acquire an image of a subject is calibrated and default dispersion correction parameters are set. Default dispersion management parameters associated with a region of the image of the subject are also set. The image of the subject is acquires after setting the default dispersion correction parameters and the default dispersion management parameters. A quality of the acquired image is compared to a quality metric for the acquired image. The dispersion correction parameters are adjusted if the quality of the acquired image does not meet or exceed the quality metric for the acquired image. The acquired image is reprocesses based on the adjusted dispersion correction parameters. The steps of comparing, adjusting and reprocessing are repeated until the acquired image meets or exceeds the quality metric for the acquired image.

    摘要翻译： 用于管理频域光学相干断层扫描（FDOCT）图像分辨率的方法，系统和计算机程序产品。 用于获取被摄体图像的光谱被校准，并且设置默认色散校正参数。 还设置与被摄体的图像的区域相关联的默认色散管理参数。 在设置默认色散校正参数和默认色散管理参数后，获取被摄体的图像。 将所获取的图像的质量与所获取的图像的质量度量进行比较。 如果所获取的图像的质量不满足或超过所获取的图像的质量度量，则调整色散校正参数。 所获取的图像基于经调整的色散校正参数进行再处理。 重复比较，调整和重新处理的步骤，直到所获取的图像满足或超过所获取的图像的质量度量。