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公开(公告)号：US08579924B2
公开(公告)日：2013-11-12
申请号：US13551010
申请日：2012-07-17
CPC分类号： A61F2/0063 , A61F2002/0086 , A61F2210/0004 , A61L31/048 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/402 , A61M31/00 , C08L67/04 , C08L23/12 , C08L89/06
摘要： The present disclosure relates to implantable medical devices which include at least one mesh and at least one film pivotably attached to the mesh.
摘要翻译： 本公开涉及可植入医疗装置，其包括至少一个网眼和至少一个可枢转地连接到网状物上的膜。
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公开(公告)号：US20110232838A1
公开(公告)日：2011-09-29
申请号：US13051333
申请日：2011-03-18
申请人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
发明人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
CPC分类号： A61F2/0063 , A61B17/00234 , A61F2250/003 , A61F2250/0035 , A61F2250/0067 , A61K9/0024 , A61L27/54 , A61L27/58 , C07K5/06078 , Y10T156/10
摘要： Surgical implants of the present disclosed include a film comprising a first therapeutic agent and a mesh comprising a second therapeutic agent. The surgical implant includes a film in direct contact with a mesh. The first therapeutic agent may be released at a first rate and the second therapeutic agent may be released at a second rate.
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公开(公告)号：US08758799B2
公开(公告)日：2014-06-24
申请号：US13051333
申请日：2011-03-18
申请人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
发明人： Joshua Stopek , Amin Elachchabi , Daniel Broom , Garrett Ebersole
CPC分类号： A61F2/0063 , A61B17/00234 , A61F2250/003 , A61F2250/0035 , A61F2250/0067 , A61K9/0024 , A61L27/54 , A61L27/58 , C07K5/06078 , Y10T156/10
摘要： Surgical implants are provided which include a film comprising a first therapeutic agent and a mesh comprising a second therapeutic agent. The surgical implant includes a film in direct contact with a mesh. The first therapeutic agent may be released at a first rate and the second therapeutic agent may be released at a second rate.
摘要翻译： 提供了外科植入物，其包括包含第一治疗剂的膜和包含第二治疗剂的网。 手术植入物包括与网状物直接接触的膜。 第一治疗剂可以以第一速率释放，并且第二治疗剂可以以第二速率释放。
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14.发明授权公开(公告)号：US08632839B2
公开(公告)日：2014-01-21
申请号：US13239983
申请日：2011-09-22
申请人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
发明人： Joshua Stopek , Garrett Ebersole , Amin Elachchabi , Daniel Broom
CPC分类号： A61K9/7007 , A61K9/0024 , A61K47/34 , A61L31/16 , A61L2300/402 , A61L2300/416
摘要： The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the self-supporting films are also disclosed.
摘要翻译： 本公开涉及用于递送含有至少一种疏水性聚合物和至少一种治疗剂的治疗剂的自支撑膜。 还公开了形成自支撑膜的方法。
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公开(公告)号：US20130030360A1
公开(公告)日：2013-01-31
申请号：US13551010
申请日：2012-07-17
CPC分类号： A61F2/0063 , A61F2002/0086 , A61F2210/0004 , A61L31/048 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/402 , A61M31/00 , C08L67/04 , C08L23/12 , C08L89/06
摘要： The present disclosure relates to implantable medical devices which include at least one mesh and at least one film pivotably attached to the mesh.
摘要翻译： 本公开涉及可植入医疗装置，其包括至少一个网眼和至少一个可枢转地连接到网状物上的膜。
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公开(公告)号：US20120010637A1
公开(公告)日：2012-01-12
申请号：US13173659
申请日：2011-06-30
IPC分类号： A61B17/00
CPC分类号： A61F2/0063 , A61F2/0045 , A61F2210/0004 , A61F2250/0067 , A61F2250/0071
摘要： The present disclosure relates to self-detachable medical devices containing a detachable film layer and polymeric film layer.
摘要翻译： 本公开涉及包含可拆卸膜层和聚合物膜层的可自行拆卸的医疗装置。
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公开(公告)号：US09782957B2
公开(公告)日：2017-10-10
申请号：US13589222
申请日：2012-08-20
申请人： Jon T. Reinprecht , Seth Gleiman , Amin Elachchabi , Ryan Witherell , Joshua Stopek , Garrett Ebersole
发明人： Jon T. Reinprecht , Seth Gleiman , Amin Elachchabi , Ryan Witherell , Joshua Stopek , Garrett Ebersole
IPC分类号： A61M5/00 , B05D3/12 , B32B27/36 , A61L27/54 , B29C47/00 , B32B7/12 , B32B9/02 , B32B23/00 , B32B27/08
CPC分类号： B32B27/36 , A61L27/54 , A61L2300/402 , A61L2420/08 , B29C47/0021 , B32B7/12 , B32B9/02 , B32B23/00 , B32B27/08 , B32B2250/244 , B32B2255/10 , B32B2255/26 , B32B2307/7163 , B32B2535/00
摘要： Medical devices described herein include a melt-pressed film having first and second diffusion barrier layers disposed thereon. The melt-pressed film and the barrier layers comprise bioabsorbable copolymers. In a further aspect, a therapeutic agent, such as an analgesic is included in the medical device.
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公开(公告)号：US20130053765A1
公开(公告)日：2013-02-28
申请号：US13589222
申请日：2012-08-20
申请人： Jon T. Reinprecht , Seth Gleiman , Amin Elachchabi , Ryan Witherell , Joshua Stopek , Garrett Ebersole
发明人： Jon T. Reinprecht , Seth Gleiman , Amin Elachchabi , Ryan Witherell , Joshua Stopek , Garrett Ebersole
CPC分类号： B32B27/36 , A61L27/54 , A61L2300/402 , A61L2420/08 , B29C47/0021 , B32B7/12 , B32B9/02 , B32B23/00 , B32B27/08 , B32B2250/244 , B32B2255/10 , B32B2255/26 , B32B2307/7163 , B32B2535/00
摘要： Medical devices described herein include a melt-pressed film having first and second diffusion barrier layers disposed thereon. The melt-pressed film and the barrier layers comprise bioabsorbable copolymers. In a further aspect, a therapeutic agent, such as an analgesic is included in the medical device.
摘要翻译： 本文所述的医疗装置包括其上设置有第一和第二扩散阻挡层的熔融膜。 熔融膜和阻隔层包括生物可吸收共聚物。 在另一方面，治疗剂，例如止痛剂包括在医疗装置中。
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公开(公告)号：US09216240B2
公开(公告)日：2015-12-22
申请号：US12987259
申请日：2011-01-10
申请人： Daniel Broom , Joshua Stopek , Amin Elachchabi
发明人： Daniel Broom , Joshua Stopek , Amin Elachchabi
CPC分类号： A61L31/16 , A61F2/0063 , A61L15/44 , A61L27/54 , A61L2300/402 , A61L2300/45 , A61L2300/602
摘要： A medical device includes a substrate having at least one surface. The surface has a central portion and a peripheral portion. At least one bioactive agent is disposed over at least a portion of the surface. The medical device having a concentration gradient of the at least one bioactive between the central and peripheral portions.
摘要翻译： 医疗装置包括具有至少一个表面的基底。 表面具有中心部分和周边部分。 在表面的至少一部分上设置至少一种生物活性剂。 所述医疗装置具有在所述中央部分和所述周边部分之间的所述至少一种生物活性物的浓度梯度。
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公开(公告)号：US20120183583A1
公开(公告)日：2012-07-19
申请号：US13344858
申请日：2012-01-06
申请人： Joshua Stopek , Amin Elachchabi , Daniel Broom
发明人： Joshua Stopek , Amin Elachchabi , Daniel Broom
IPC分类号： A61K9/00 , A61K47/34 , A61K47/32 , A61P7/04 , A61P25/04 , A61P23/00 , A61P31/00 , A61P7/02 , A61L33/06 , A61K47/36
CPC分类号： A61L31/146 , A61F2/0063 , A61F2/0077 , A61F2002/0081 , A61F2002/0086 , A61L27/14 , A61L27/54 , A61L27/56 , A61L31/04 , A61L31/08 , A61L31/16 , A61L2300/60 , A61L2420/02
摘要： The present disclosure relates to a medical device and methods of making the same. The medical device includes a porous substrate and at least one film. The film is formed within the pore of the substrate. The film is intra-porous and does not contact adjacent pores or films.
摘要翻译： 本公开涉及一种医疗装置及其制造方法。 医疗装置包括多孔基底和至少一个膜。 该膜形成在基底的孔内。 该膜是多孔的并且不接触相邻的孔或膜。
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