公开(公告)号：US07345205B2

公开(公告)日：2008-03-18

申请号：US10519684

申请日：2003-07-14

申请人： Hans-Georg Goebbel ,  Gerd Kaibel ,  Christian Miller ,  Walter Dobler ,  Thomas Dirnsteiner ,  Thilo Hahn ,  Klaus Breuer ,  Werner Aquila

发明人： Hans-Georg Goebbel ,  Gerd Kaibel ,  Christian Miller ,  Walter Dobler ,  Thomas Dirnsteiner ,  Thilo Hahn ,  Klaus Breuer ,  Werner Aquila

IPC分类号： C07C45/62

CPC分类号： C07C45/62 ,  C07C49/04

摘要： A process is described for preparing tetrahydrogeranylacetone in which pseudoionone, geranylacetone and/or dihydrogeranylacetone in a liquid phase, in which particles of a catalyst which is capable of preferentially hydrogenating carbon-carbon double bonds over carbon-oxygen double bonds are suspended, is conducted through a device which inhibits the transport of the catalyst particles in the presence of a hydrogen-containing gas.

摘要翻译： 描述了一种制备四氢ger anyl anyl A A is ger ger ger through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through through 在含氢气体的存在下抑制催化剂颗粒的输送的装置。

公开(公告)号：US20050197504A1

公开(公告)日：2005-09-08

申请号：US10515625

申请日：2003-07-07

申请人： Gerd Kaibel ,  Martin Merger ,  Thomas Domschke ,  Petra Deckert ,  Friedrich Sauer

发明人： Gerd Kaibel ,  Martin Merger ,  Thomas Domschke ,  Petra Deckert ,  Friedrich Sauer

IPC分类号： C07D307/62 ,  C07D305/12

CPC分类号： C07D307/62 ,  Y02P20/582

摘要： The invention relates to a method for the separation of ascorbic acid from a mixture containing ascorbic acid and 2-keto-L-gulonic acid in a polar, preferably aqueous solvent, by means of liquid/liquid extraction using an amide. The method preferably also comprises steps for the back-extraction of the ascorbic acid, recycling of the extraction solvent and/or the back extraction solvent and for isolation of the ascorbic acid from the back extraction solvent. The invention further relates to a method for the production of ascorbic acid from KGA and isolation of the ascorbic acid so produced.

摘要翻译： 本发明涉及通过使用酰胺的液/液萃取从抗坏血酸和2-酮-L-古洛糖酸的混合物中分离抗坏血酸在极性，优选水性溶剂中的方法。 该方法优选还包括用于反萃取抗坏血酸的步骤，提取溶剂和/或反萃取溶剂的再循环以及用于从反萃取溶剂中分离抗坏血酸的步骤。 本发明还涉及从KGA生产抗坏血酸并分离如此生产的抗坏血酸的方法。

公开(公告)号：US06831182B2

公开(公告)日：2004-12-14

申请号：US10433424

申请日：2003-06-04

申请人： Holger Borchert ,  Stephan Schlitter ,  Rolf-Hartmuth Fischer ,  Markus Rösch ,  Frank Stein ,  Ralf-Thomas Rahn ,  Alexander Weck ,  Gerd Kaibel

发明人： Holger Borchert ,  Stephan Schlitter ,  Rolf-Hartmuth Fischer ,  Markus Rösch ,  Frank Stein ,  Ralf-Thomas Rahn ,  Alexander Weck ,  Gerd Kaibel

IPC分类号： C07D30708

CPC分类号： C07D307/08

摘要： The present invention relates to a process for the gas-phase hydrogenation of C4-dicarboxylic acids and/or their derivatives over a catalyst based on copper oxide to give substituted or unsubstituted &ggr;-butyrolactone and/or tetrahydrofuran, which comprises, which a first reaction zone in which the C4-dicarboxylic acid and/or its derivatives is/are reacted to give a mixture comprising a substituted or unsubstituted &ggr;-butyrolactone as main product and a subsequent second reaction zone in which the substituted or unsubstituted &ggr;-butyrolactone present in the mixture from the first hydrogenation step is reacted at a temperature lower than the temperature in the first hydrogenation step to give substituted or unsubstituted tetrahydrofuran.

公开(公告)号：US06387222B1

公开(公告)日：2002-05-14

申请号：US09538503

申请日：2000-03-30

申请人： Christian Tragut ,  Gerd Kaibel

发明人： Christian Tragut ,  Gerd Kaibel

IPC分类号： B01D342

CPC分类号： B01D3/141 ,  B01D3/14 ,  B01D3/146 ,  C07C29/80 ,  Y10S203/20 ,  C07C31/12 ,  C07C31/20

摘要： A method of distillation for separating a material which is solid at ambient temperature from a lower boiling and lower melting point material, and the apparatus.

摘要翻译： 一种蒸馏方法，用于将环境温度下为固体的材料与较低沸点和较低熔点的材料以及该装置分离。

公开(公告)号：US06329554B1

公开(公告)日：2001-12-11

申请号：US09391619

申请日：1999-09-07

申请人： Carsten Oost ,  Manfred Stroezel ,  Heinz Etzrodt ,  Dietmar Weller ,  Bernhard Bockstiegel ,  Klaus Reimer ,  Gerd Kaibel ,  Hagen Jaedicke

发明人： Carsten Oost ,  Manfred Stroezel ,  Heinz Etzrodt ,  Dietmar Weller ,  Bernhard Bockstiegel ,  Klaus Reimer ,  Gerd Kaibel ,  Hagen Jaedicke

IPC分类号： C07C4500

CPC分类号： C07C45/676 ,  B01D3/009 ,  B01D3/14 ,  B01D3/141 ,  B01D3/322 ,  B01J19/24 ,  B01J2219/00103 ,  B01J2219/00162 ,  B01J2219/00777 ,  B01J2219/32268 ,  Y02P20/127 ,  Y02P20/582 ,  C07C49/203 ,  C07C49/255

摘要： Process for the continuous preparation of unsaturated ketones of the formula I where the dashed line can be an additional C—C bond, R1 is an alkyl, and R2 is an aliphatic hydrocarbon having from 1 to 37 carbons, a cycloalkyl or a cycloalkylalkyl, by reacting an unsaturated alcohol of the formula II  with an alkyl acetoacetate of the formula III where R3 is an alkyl having from 1 to 5 carbons, in the presence or organic aluminum compounds as catalyst.

摘要翻译： 用于连续制备式I的不饱和酮的方法，其中虚线可以是另外的CC键，R 1是烷基，R 2是具有1至37个碳的脂族烃，环烷基或环烷基烷基，通过使不饱和的 式II的醇与式III的乙酰乙酸烷基酯反应，其中R 3是具有1至5个碳的烷基，在有机铝化合物作为催化剂存在下进行。

公开(公告)号：US06303823B2

公开(公告)日：2001-10-16

申请号：US09729459

申请日：2000-12-05

申请人： Andreas Kramer ,  Christian Knoll ,  Johann-Peter Melder ,  Wolfgang Siegel ,  Gerd Kaibel

发明人： Andreas Kramer ,  Christian Knoll ,  Johann-Peter Melder ,  Wolfgang Siegel ,  Gerd Kaibel

IPC分类号： C07C4573

CPC分类号： C07C45/74 ,  C07C45/62 ,  C07C45/73 ,  C07C49/04 ,  C07C49/203

摘要： A process for preparing ketones by so-called “crossed aldol condensation” of a ketone with an aldehyde in the presence of a catalyst system consisting of approximately equimolar amounts of a secondary amine and of a carboxylic acid containing at least 2 C atoms, to form an &agr;,&bgr;-unsaturated ketone, and, where appropriate, subsequent catalytic hydrogenation. The process is used in particular for preparing 6-methyl-3-hepten-2-one by reacting acetone with isovaleraldehyde, and for preparing its hydrogenation product, 6-methylheptan-2-one, which is an important precursor for numerous active substances, in particular for preparing lipid-soluble vitamins such as vitamin E.

摘要翻译： 在由大约等摩尔量的仲胺和含有至少2个C原子的羧酸组成的催化剂体系的存在下，通过所谓的“交叉醛醇缩合”酮与醛制备酮的方法，以形成 α，β-不饱和酮，以及适当的后续催化氢化。该方法特别用于通过丙酮与异戊醛反应制备6-甲基-3-庚烯-2-酮，并用于制备其氢化产物6 - 甲基庚-2-酮，其是许多活性物质的重要前体，特别是用于制备脂溶性维生素如维生素E.

公开(公告)号：US06214172B1

公开(公告)日：2001-04-10

申请号：US08845556

申请日：1997-04-25

申请人： Carsten Gröning ,  Klaus Ebel ,  Gerd Kaibel ,  Jörg Therre ,  Jürgen Koopmann ,  Helmuth Menig ,  Gerhard Fritz ,  Rainer Dietz

发明人： Carsten Gröning ,  Klaus Ebel ,  Gerd Kaibel ,  Jörg Therre ,  Jürgen Koopmann ,  Helmuth Menig ,  Gerhard Fritz ,  Rainer Dietz

IPC分类号： B01D336

CPC分类号： C07C45/71 ,  C07C45/84 ,  Y02P20/582 ,  Y10S203/13 ,  C07C49/175

摘要： In a process for the preparation of methylglyoxal dimethyl acetal from methylglyoxal and methanol in the presence of an acidic ion exchanger, water is introduced in an amount sufficient to form an acidic reaction mixture in which the acetal product and water form an azeotropic mixture, with or without the retention of some methanol reactant. After subjecting a single phase acidic reaction mixture to an azeotropic distillation, it will separate into two distinct liquid phases with a simple recovery of the acetal product from the aqueous phase.

摘要翻译： 在酸性离子交换剂存在下，从甲基乙二醛和甲醇制备甲基乙二醛缩二甲醇的方法中，以足以形成酸缩反应混合物的量引入水，其中缩醛产物和水形成共沸混合物， 没有保留一些甲醇反应物。 在使单相酸性反应混合物进行共沸蒸馏后，将从水相中简单回收缩醛产物，分离成两个不同的液相。

公开(公告)号：US5939589A

公开(公告)日：1999-08-17

申请号：US820001

申请日：1997-03-18

申请人： Gerd Kaibel ,  Franz Josef Brocker ,  Manfred Stroezel

发明人： Gerd Kaibel ,  Franz Josef Brocker ,  Manfred Stroezel

IPC分类号： B01F5/06 ,  B01J8/00 ,  B01J8/06 ,  B01J8/18 ,  B01J8/20 ,  B01J8/22 ,  B01J8/34 ,  C07C45/62 ,  C07C49/00

CPC分类号： C07C45/62 ,  B01J8/0015 ,  B01J8/007 ,  B01J8/06 ,  B01J8/1863 ,  B01J8/20 ,  B01J8/22 ,  B01J8/34

摘要： Catalytic reactions are carried out in a reactor which contains a liquid phase in which at least one catalyst is suspended, and which may additionally contain a gas phase, by a process in which the liquid phase and, if present, also the gas phase are fed, at least partly, through an apparatus having orifices or channels in the reactor, the hydraulic diameter of which orifices or channels is from 0.5 to 20 mm, preferably from 1 to 10 mm, particularly preferably from 1 to 3 mm.

摘要翻译： 催化反应在包含液相的反应器中进行，其中至少一种催化剂悬浮在其中，并且其可以另外含有气相，通过其中液相和（如果存在的话）气相被加料的方法 至少部分地通过具有反应器中的孔或通道的装置，其孔径或通道的水力直径为0.5至20mm，优选为1至10mm，特别优选为1至3mm。

公开(公告)号：US4720327A

公开(公告)日：1988-01-19

申请号：US420485

申请日：1982-09-20

申请人： Werner Aquila ,  Axel Nissen ,  Gerd Kaibel ,  Michael Horner ,  Walter Rebafka

发明人： Werner Aquila ,  Axel Nissen ,  Gerd Kaibel ,  Michael Horner ,  Walter Rebafka

IPC分类号： A61K8/33 ,  A61Q13/00 ,  B01D3/34 ,  C07B31/00 ,  C07B63/00 ,  C07C27/00 ,  C07C29/141 ,  C07C29/80 ,  C07C31/04 ,  C07C33/025 ,  C07C45/00 ,  C07C45/82 ,  C07C47/21 ,  C07C67/00 ,  C11B9/00 ,  C11B9/02 ,  B01D3/38

CPC分类号： C07C45/82 ,  B01D3/34 ,  C11B9/027 ,  Y10S203/24 ,  Y10S203/90

摘要： Distillative separation of liquid mixtures of one or more water-insoluble substances which have boiling points higher than that of water and one or more substances which have boiling points lower than that of water or which form azeotropes having boiling points lower than that of water, wherein the mixture to be distilled is mixed with a quantity of water such that the boiling point of the water under the pressure applied limits the bottom temperature of the mixture of substances to be separated.

摘要翻译： 沸点高于水的一种或多种水不溶性物质的液体混合物的蒸馏分离和一种或多种沸点低于水的沸点或者沸点低于水的沸点的物质，其中 将要蒸馏的混合物与一定量的水混合，使得在施加压力下的水的沸点限制待分离物质的混合物的底部温度。

公开(公告)号：US4133836A

公开(公告)日：1979-01-09

申请号：US801561

申请日：1977-05-31

申请人： Axel Nissen ,  Gerd Kaibel

发明人： Axel Nissen ,  Gerd Kaibel

IPC分类号： C07C41/50 ,  B01J27/00 ,  C07C41/00 ,  C07C41/54 ,  C07C43/30 ,  C07C43/303 ,  C07C67/00 ,  C07C69/12 ,  C07C69/73

摘要： A process for the manufacture of acetals by reacting aliphatic aldehydes with aliphatic alcohols, especially olefinically unsaturated aldehydes and allyl alcohols, in the presence of a distillable acid, especially nitric acid, using a rectifying column as the reaction vessel. The products may be used as starting materials for plastics, active substances, scents and vitamins.

摘要翻译： 通过使用精馏塔作为反应容器，在可馏出的酸，特别是硝酸的存在下，使脂族醛与脂族醇，特别是烯属不饱和醛和烯丙醇反应来制造缩醛的方法。 该产品可用作塑料，活性物质，气味和维生素的起始原料。