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公开(公告)号:US08173360B2
公开(公告)日:2012-05-08
申请号:US12576232
申请日:2009-10-08
CPC分类号: C07D417/04 , A61K31/00 , A61K31/5415 , C07D279/08 , G01N2333/52 , G01N2500/02
摘要: The cell death inhibitor comprising a substance capable of binding to macrophage migration inhibitory factor is useful as a preventive/therapeutic agent for, e.g., heart diseases, neurodegenerative diseases, cerebrovascular diseases, central nervous infections, traumatic diseases, demyelinating diseases, bone/joint diseases, kidney diseases, liver diseases, myelodysplastic diseases, arteriosclerosis, diabetes, pulmonary hypertension, sepsis, inflammatory bowel diseases, autoimmune diseases, failure accompanying rejection in organ transplantation, AIDS, cancer, etc.
摘要翻译: 包含能够结合巨噬细胞迁移抑制因子的物质的细胞死亡抑制剂可用作例如心脏病,神经变性疾病,脑血管疾病,中枢神经感染,创伤性疾病,脱髓鞘疾病,骨/关节疾病的预防/治疗剂 肾脏疾病,肝脏疾病,骨髓增生异常性疾病,动脉硬化,糖尿病,肺动脉高压,败血症,炎性肠病,自身免疫疾病,器官移植排斥反应失败,艾滋病,癌症等。
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公开(公告)号:US07846703B2
公开(公告)日:2010-12-07
申请号:US11866148
申请日:2007-10-02
申请人: Eiji Kobayashi , Yuki Ueda , Yoshimi Sato , Takashi Uemori , Hiroyuki Mukai , Ikunoshin Kato
发明人: Eiji Kobayashi , Yuki Ueda , Yoshimi Sato , Takashi Uemori , Hiroyuki Mukai , Ikunoshin Kato
CPC分类号: C12N9/1241
摘要: A polymerase activity is effectively enhanced by adding an anionic surfactant, in particular an anionic surfactant having a polyethoxyl group, to a reaction mixture containing a polymerase.
摘要翻译: 通过向含有聚合酶的反应混合物中加入阴离子表面活性剂,特别是具有聚乙氧基的阴离子表面活性剂,可有效提高聚合酶活性。
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公开(公告)号:US06597027B1
公开(公告)日:2003-07-22
申请号:US09709423
申请日:2000-11-13
IPC分类号: H01L2100
CPC分类号: H01L28/75 , H01L28/55 , Y10S438/957
摘要: It is disclosed a dielectric element comprising a lower electrode, a dielectric layer, and an upper electrode which are provided on a substrate, in which at least one of the electrodes is a Pt layer, a Ru layer is used as a base layer for the Pt layer. In the fabrication of the dielectric element, the Pt layer is formed by electroplating, a photoresist pattern is used as a plating mask, and an Ru layer is formed as a seed layer. The present invention makes it possible to provide a dielectric element using Pt as an electrode material, that is capable of easily forming a Pt electrode having excellent electrical characteristics without generating voids or seams, that is capable of forming a fine pattern, and that does not occur contamination in a processing chamber, and a method for fabricating a dielectric element of having the characteristics mentioned above.
摘要翻译: 公开了一种介电元件,其包括设置在基板上的下电极,电介质层和上电极,其中至少一个电极为Pt层,Ru层用作基极层 Pt层。 在电介质元件的制造中,通过电镀形成Pt层,使用光致抗蚀剂图案作为电镀掩模,并且形成Ru层作为籽晶层。 本发明使得可以提供使用Pt作为电极材料的电介质元件,其能够容易地形成能够形成精细图案的电气特性优异的Pt电极而不产生空隙或接缝,并且不 在处理室中发生污染,以及具有上述特征的制造电介质元件的方法。
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公开(公告)号:US06218150B1
公开(公告)日:2001-04-17
申请号:US09446504
申请日:1999-12-23
申请人: Takashi Uemori , Yoshimi Sato , Tomoko Fujita , Kazue Miyake , Hiroyuki Mukai , Kiyozo Asada , Ikunoshin Kato
发明人: Takashi Uemori , Yoshimi Sato , Tomoko Fujita , Kazue Miyake , Hiroyuki Mukai , Kiyozo Asada , Ikunoshin Kato
IPC分类号: C12P1934
CPC分类号: C12N9/1252
摘要: The present invention relates to a thermostable DNA polymerase-associated factor capable of enhancing DNA synthesizing-activity of a DNA polymerase; a thermostable DNA polymerase-associated factor possessing an activity of binding to a DNA polymerase and a method for producing the same; a gene encoding the DNA polymerase-associated factor; a method of DNA synthesis by using a DNA polymerase in the presence of the DNA polymerase-associated factor; and a kit comprising the DNA polymerase-associated factor. According to the present invention, there can be provided in vitro DNA synthesis and a DNA amplification system which are more excellent than conventional techniques by utilizing the DNA polymerase-associated factor of the present invention.
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公开(公告)号:US4742886A
公开(公告)日:1988-05-10
申请号:US15700
申请日:1987-02-17
申请人: Yoshimi Sato
发明人: Yoshimi Sato
CPC分类号: B60R22/322
摘要: A seat belt apparatus comprises an engaging device attached to a seat belt, a buckle device engagable with the engaging device, and a device for releasing the engagement between the engaging device and the buckle device in association with the opening operation of a door.
摘要翻译: 安全带装置包括附接到安全带的接合装置,可与接合装置接合的带扣装置,以及用于与门的打开操作相关联地释放接合装置和带扣装置之间的接合的装置。
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公开(公告)号:US4310178A
公开(公告)日:1982-01-12
申请号:US103578
申请日:1979-12-14
申请人: Yoshimi Sato
发明人: Yoshimi Sato
CPC分类号: B60R22/04
摘要: A three points passive seat belt assembly which automatically holds or releases vehicle passenger when the door is closed or opened. Extendable pull means holds lap belt portion of the belt at a higher position when the door is opened.
摘要翻译: 三点无源安全带组件,当门关闭或打开时,自动保持或释放车辆乘客。 可拉伸拉手在门打开时将皮带的腰带部分保持在更高的位置。
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公开(公告)号:US20110131088A1
公开(公告)日:2011-06-02
申请号:US12953653
申请日:2010-11-24
申请人: Yoshiaki Oe , Yun Wang , Tsuyoshi Gotanda , Shiomi Matsui , Yoshimi Sato
发明人: Yoshiaki Oe , Yun Wang , Tsuyoshi Gotanda , Shiomi Matsui , Yoshimi Sato
IPC分类号: G06Q30/00
CPC分类号: G06Q30/02 , G06Q30/0224 , G06Q30/0633
摘要: According to one embodiment, a purchase file stores, by commodity, as information concerning purchase-desired commodities specified by a specifying unit, at least the numbers of purchase-planned items and purchase-planned amounts of the commodities. A privilege granting unit grants a privilege to the purchase of the purchase-desired commodities when a total of a total number of purchased items of the purchase-desired commodities obtained from a purchase-results storing unit, which stores information concerning commodities already purchased by a customer, and the numbers of purchase-planned items of the same commodities stored in the purchase file or a total of a total amount of purchased items of the purchase-desired commodities obtained from the purchase-results storing unit and purchase-planned amounts of the same commodities stored in the purchase file is equal to or larger than a threshold. A privilege display unit displays information concerning the privilege granted by the privilege granting unit.
摘要翻译: 根据一个实施例,购买文件按商品存储关于由指定单元指定的购买期望商品的信息,至少购买计划项目的数量和商品的购买计划量。 当从购买结果存储单元获得的总购买物品的购买物品总数中存储有关已经购买的商品的信息时,特权授予单元授予购买所需商品的权利, 客户以及存储在购买文件中的相同商品的购买计划的数量的数量,或从购买结果存储单元获得的购买所需商品的购买物品的总量以及购买计划的购买计划量 存储在购买文件中的相同商品等于或大于阈值。 特权显示单元显示有关特权授予单元授予的权限的信息。
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公开(公告)号:US07704713B2
公开(公告)日:2010-04-27
申请号:US11628268
申请日:2005-05-12
申请人: Yoshimi Sato , Kazue Nishiwaki , Nana Shimada , Shigekazu Hokazono , Takashi Uemori , Hiroyuki Mukai , Ikunoshin Kato
发明人: Yoshimi Sato , Kazue Nishiwaki , Nana Shimada , Shigekazu Hokazono , Takashi Uemori , Hiroyuki Mukai , Ikunoshin Kato
CPC分类号: C12Q1/686 , C12N9/1252 , C12Q2521/101
摘要: A polypeptide having a high fidelity DNA polymerase activity and thus being useful as a genetic engineering reagent; a gene encoding this polypeptide; a method of producing the polypeptide; and a method of amplifying a nucleic acid by using the polypeptide.
摘要翻译: 具有高保真DNA聚合酶活性的多肽,因此可用作遗传工程试剂; 编码该多肽的基因; 一种产生该多肽的方法; 以及通过使用多肽扩增核酸的方法。
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公开(公告)号:US20100099106A1
公开(公告)日:2010-04-22
申请号:US12576232
申请日:2009-10-08
申请人: Haruhide Kimura , Yoshimi Sato , Masayuki Takizawa
发明人: Haruhide Kimura , Yoshimi Sato , Masayuki Takizawa
IPC分类号: C12Q1/68
CPC分类号: C07D417/04 , A61K31/00 , A61K31/5415 , C07D279/08 , G01N2333/52 , G01N2500/02
摘要: The cell death inhibitor comprising a substance capable of binding to macrophage migration inhibitory factor is useful as a preventive/therapeutic agent for, e.g., heart diseases, neurodegenerative diseases, cerebrovascular diseases, central nervous infections, traumatic diseases, demyelinating diseases, bone/joint diseases, kidney diseases, liver diseases, myelodysplastic diseases, arteriosclerosis, diabetes, pulmonary hypertension, sepsis, inflammatory bowel diseases, autoimmune diseases, failure accompanying rejection in organ transplantation, AIDS, cancer, etc.
摘要翻译: 包含能够结合巨噬细胞迁移抑制因子的物质的细胞死亡抑制剂可用作例如心脏病,神经变性疾病,脑血管疾病,中枢神经感染,创伤性疾病,脱髓鞘疾病,骨/关节疾病的预防/治疗剂 肾脏疾病,肝脏疾病,骨髓增生异常性疾病,动脉硬化,糖尿病,肺动脉高压,败血症,炎症性肠病,自身免疫疾病,器官移植排斥反应失败,艾滋病,癌症等。
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公开(公告)号:US20090098613A1
公开(公告)日:2009-04-16
申请号:US12285866
申请日:2008-10-15
申请人: Kiyozo Asada , Takashi Uemori , Yoshimi Sato , Tomoko Fujita , Kazue Miyake , Osamu Takeda , Hiroyuki Mukai , Ikunoshin Kato
发明人: Kiyozo Asada , Takashi Uemori , Yoshimi Sato , Tomoko Fujita , Kazue Miyake , Osamu Takeda , Hiroyuki Mukai , Ikunoshin Kato
IPC分类号: C12P19/34
CPC分类号: C12P19/34 , C12N9/1252 , C12N9/96 , C12Q1/6806 , Y10S435/975 , C12Q2521/107
摘要: A DNA synthesis reaction-enhancer comprising at least one kind selected from the group consisting of acidic substances and cationic complexes; a DNA synthesis method in which during a DNA synthesis reaction a reaction is carried out in the presence of the above enhancer by using DNA polymerase; a DNA synthesis reaction composition comprising the above enhancer; a DNA synthesis reaction composition comprising two or more kinds of DNA polymerases each having 3′→5′ exonuclease activity; a DNA synthesis method in which during a DNA synthesis reaction two or more kinds of DNA polymerases each having 3′→5′ exonuclease activity are used; a kit for use in in vitro DNA synthesis, comprising two or more kinds of DNA polymerases each having 3′→5′ exonuclease activity; and a kit for use in in vitro DNA synthesis, wherein the kit comprises the DNA synthesis reaction-enhancer and DNA polymerase. According to the present invention, DNA synthesis can be carried out at an efficiency more excellent as compared to conventional DNA synthesis reaction.
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