公开(公告)号：US20120180799A1

公开(公告)日：2012-07-19

申请号：US13324764

申请日：2011-12-13

申请人： D. Russell Pflueger ,  Christopher Paul Thompson ,  Steven R. Bacich ,  Richard L. Quick ,  Matthew Yurek

发明人： D. Russell Pflueger ,  Christopher Paul Thompson ,  Steven R. Bacich ,  Richard L. Quick ,  Matthew Yurek

IPC分类号： A61F5/56

CPC分类号： A61F5/566

摘要： Apparatus and methods are provided for treating sleep apnea, snoring, and the like using an implant within an oropharyngeal region adjacent an anterior longitudinal ligament. The implant may include a relatively narrow central region between first and second relatively wide outer regions. In one embodiment, one of the outer regions is compressible to allow the outer region to be directed through or behind the ligament such that the central region is disposed within or behind the ligament, the outer region being resiliently expandable after passing through or behind the ligament. In another embodiment, the implant may include one or more tines or other features that may be directed into adjacent tissue to secure the implant within the oropharyngeal region.

摘要翻译： 提供了使用邻近前纵韧带的口咽部区域内的植入物来治疗睡眠呼吸暂停，打鼾等的装置和方法。 植入物可以包括在第一和第二相对宽的外部区域之间的相对窄的中心区域。 在一个实施例中，外部区域中的一个是可压缩的，以允许外部区域被引导通过韧带的后面或后面，使得中心区域设置在韧带内或后面，外部区域在穿过或穿过韧带之后可弹性地扩张 。 在另一个实施例中，植入物可以包括一个或多个尖齿或可被引导到相邻组织中的其它特征，以将植入物固定在口咽部区域内。

公开(公告)号：US09265649B2

公开(公告)日：2016-02-23

申请号：US13324764

申请日：2011-12-13

申请人： D. Russell Pflueger ,  Christopher Paul Thompson ,  Steven R. Bacich ,  Richard L. Quick ,  Matthew Yurek

发明人： D. Russell Pflueger ,  Christopher Paul Thompson ,  Steven R. Bacich ,  Richard L. Quick ,  Matthew Yurek

IPC分类号： A61F5/56

CPC分类号： A61F5/566

摘要： Apparatus and methods are provided for treating sleep apnea, snoring, and the like using an implant within an oropharyngeal region adjacent an anterior longitudinal ligament. The implant may include a relatively narrow central region between first and second relatively wide outer regions. In one embodiment, one of the outer regions is compressible to allow the outer region to be directed through or behind the ligament such that the central region is disposed within or behind the ligament, the outer region being resiliently expandable after passing through or behind the ligament. In another embodiment, the implant may include one or more tines or other features that may be directed into adjacent tissue to secure the implant within the oropharyngeal region.

摘要翻译： 提供了使用邻近前纵韧带的口咽部区域内的植入物来治疗睡眠呼吸暂停，打鼾等的装置和方法。 植入物可以包括在第一和第二相对宽的外部区域之间的相对窄的中心区域。 在一个实施例中，外部区域之一是可压缩的，以允许外部区域被引导通过韧带的后面或后面，使得中心区域设置在韧带内或后面，外部区域在穿过或穿过韧带之后可弹性地扩张 。 在另一个实施例中，植入物可以包括一个或多个尖齿或可被引导到相邻组织中的其它特征，以将植入物固定在口咽部区域内。

公开(公告)号：US07988735B2

公开(公告)日：2011-08-02

申请号：US12316789

申请日：2008-12-16

申请人： Matthew Yurek ,  Jerome Segal ,  Kabir Gambhir ,  Kurt Vedder ,  Robert Huffman

发明人： Matthew Yurek ,  Jerome Segal ,  Kabir Gambhir ,  Kurt Vedder ,  Robert Huffman

IPC分类号： A61F2/44

CPC分类号： A61F2/441 ,  A61B17/04 ,  A61B17/064 ,  A61B17/842 ,  A61B17/86 ,  A61B17/869 ,  A61F2/28 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30092 ,  A61F2002/302 ,  A61F2002/30235 ,  A61F2002/30462 ,  A61F2002/30464 ,  A61F2002/30469 ,  A61F2002/3052 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30601 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2002/4629 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0085 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2310/00011 ,  A61F2310/00353 ,  A61F2310/00359 ,  A61F2310/00365

摘要： The present invention relates to a device and method to perform 1) disk fusing, 2) an artificial replacement of the nucleus, 3) artificial replacement of the annulus, or 4), an artificial replacement of both the nucleus and annulus. The device is designed to be placed into the inter-vertebral space following discectomy. The invention includes a delivery catheter and an expandable continuous mesh that has a torus configuration with a lumen within the mesh and a center hole. The mesh can be diametrically expanded in diameter into the disc space whereby various materials can be injected into the lumen and/or the center hole.

摘要翻译： 本发明涉及一种执行1）盘式定影的装置和方法，2）人造置换核，3）人造置换环，或4）人造置换核和环。 该装置被设计成放置在椎间盘切除术之后的脊椎间隙中。 本发明包括输送导管和可扩张的连续网，其具有环形构型，其具有网内的内腔和中心孔。 网孔可以直径地径向扩大到椎间盘空间中，从而可以将各种材料注入内腔和/或中心孔。

公开(公告)号：US20070225753A1

公开(公告)日：2007-09-27

申请号：US11676248

申请日：2007-02-16

申请人： Kevin Connors ,  William Pintauro ,  Sheila Wallin ,  John Kilcoyne ,  Hung Cao ,  Khoi Nguyen ,  Matthew Yurek

发明人： Kevin Connors ,  William Pintauro ,  Sheila Wallin ,  John Kilcoyne ,  Hung Cao ,  Khoi Nguyen ,  Matthew Yurek

IPC分类号： A61F9/00

CPC分类号： A61F2/02 ,  A61F2/042 ,  A61F9/00781 ,  A61F2250/0067

摘要： Disclosed herein is an attenuation device, comprising a flexible housing and a high vapor pressure media having a permeability of less than 1 ml/day at body temperature through the outer wall of the flexible housing. In one embodiment, the high vapor pressure media comprises perfluorooctylbromide. In another embodiment, the high vapor pressure media comprises perfluorohexane. In yet another embodiment, the high vapor pressure media comprises perfluorodecalin. Also disclosed herein is a method of treating a patient, comprising providing a compressible attenuation device and introducing within the attenuation device at least one high vapor pressure media.

摘要翻译： 本文公开了一种衰减装置，其包括柔性壳体和高温蒸气压介质，其通过柔性壳体的外壁在体温下具有小于1ml /天的渗透性。 在一个实施方案中，高蒸气压介质包含全氟辛基溴。 在另一个实施方案中，高蒸气压介质包括全氟己烷。 在另一个实施方案中，高蒸气压介质包括全氟萘烷。 本文还公开了一种治疗患者的方法，包括提供可压缩衰减装置并在所述衰减装置内引入至少一个高蒸气压介质。

公开(公告)号：US20060287729A1

公开(公告)日：2006-12-21

申请号：US11273299

申请日：2005-11-14

申请人： Jerome Segal ,  Matthew Yurek ,  Hansen Yuan ,  Anthony Yeung

发明人： Jerome Segal ,  Matthew Yurek ,  Hansen Yuan ,  Anthony Yeung

IPC分类号： A61F2/44

CPC分类号： A61F2/441 ,  A61B17/04 ,  A61B17/064 ,  A61B17/842 ,  A61B17/86 ,  A61B17/869 ,  A61F2/28 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30092 ,  A61F2002/302 ,  A61F2002/30235 ,  A61F2002/30331 ,  A61F2002/30462 ,  A61F2002/30471 ,  A61F2002/3052 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30601 ,  A61F2002/30677 ,  A61F2002/4415 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2002/4629 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0085 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/0075 ,  A61F2220/0091 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2310/00011 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00029 ,  A61F2310/00161 ,  A61F2310/00353 ,  A61F2310/00365

摘要： The present invention relates to a device and method which may be used to reinforce the native annulus during spinal surgery. The device is a catheter based device which is placed into the inter-vertebral space following discectomy performed by either traditional surgical or endoscopic approaches. The distal end of the catheter is comprised of an expansile loop which may be increased in diameter by advancement of a portion of the catheter via its proximal end, such proximal end remaining external to the body. The expansile loop may be formed such that when the loop is diametrically contracted the loop feeds into its other end, similar to a snake eating its own tail. Stabilization of the outer portion of the loop and pulling out the inner portion will thereby increase the overall diameter of the loop while maintaining it as a closed loop or torus. The expansile loop then uses an attachment means to secure it to substantially healthy tissues of the annulus, nucleus, or endplates. The present invention comprises four embodiments and can be used to 1) facilitate disk fusing, 2) perform an artificial replacement of the nucleus, 3) perform an artificial replacement of the annulus, or 4, perform an artificial replacement of both the nucleus and annulus.

公开(公告)号：US20060287726A1

公开(公告)日：2006-12-21

申请号：US11153776

申请日：2005-06-15

申请人： Jerome Segal ,  Matthew Yurek

发明人： Jerome Segal ,  Matthew Yurek

IPC分类号： A61F2/44

CPC分类号： A61F2/441 ,  A61B17/04 ,  A61B17/064 ,  A61B17/842 ,  A61B17/86 ,  A61B17/869 ,  A61F2/28 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30092 ,  A61F2002/302 ,  A61F2002/30235 ,  A61F2002/30462 ,  A61F2002/3052 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30601 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2002/4629 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0085 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2310/00011 ,  A61F2310/00353 ,  A61F2310/00365

摘要： The present invention relates to a device and method which may be used to reinforce the native annulus during spinal surgery. The device is a catheter based device which is placed into the inter-vertebral space following discectomy performed by either traditional surgical or endoscopic approaches. The distal end of the catheter is comprised of an expansile loop which may be increased in diameter by advancement of a portion of the catheter via its proximal end, such proximal end remaining external to the body. The expansile loop may be formed of a woven or braided material and may be made of a polymer such as nylon, polyurethane, polyester, polyethylene, polypropylene or any of the well known and biocompatible polymers. Alternatively the expansile portion of the catheter may be formed from a metallic braid of stainless steel, elgiloy, Nitinol, or other biocompatible metals. The expansile loop may be formed such that when the loop is diametrically contracted the loop feeds into its other end, similar to a snake eating its own tail. Stabilization of the outer portion of the loop and pulling out the inner portion will thereby increase the overall diameter of the loop while maintaining it as a closed loop or torus. The present invention comprises four embodiments and can be used to 1) facilitate disk fusing, 2) perform an artificial replacement of the nucleus, 3) perform an artificial replacement of the annulus, or 4, perform an artificial replacement of both the nucleus and annulus.

摘要翻译： 本发明涉及可用于在脊柱手术期间加强天然环的装置和方法。 该装置是基于导管的装置，其通过传统的手术或内窥镜方法进行椎间盘切除术后放置在脊椎间隙内。 导管的远端包括可膨胀的环，其可以通过导管的一部分的近端前进而直径增加，这样的近端保持在身体外部。 膨胀环可以由织造或编织材料形成，并且可以由聚合物如尼龙，聚氨酯，聚酯，聚乙烯，聚丙烯或任何公知的和生物相容的聚合物制成。 或者，导管的膨胀部分可以由不锈钢，铍合金，镍钛诺或其他生物相容性金属的金属编织物形成。 可以形成膨胀环，使得当环径向收缩时，环进入其另一端，类似于吃自己的尾巴的蛇。 因此，环路的外部部分的稳定和拉出内部部分将由此增加环路的总直径，同时将其保持为闭环或环面。 本发明包括四个实施例，并且可以用于1）促进磁盘定影，2）进行人造核替换，3）进行环形的人工置换，或4，进行核和环的人造置换 。

公开(公告)号：US20110270399A1

公开(公告)日：2011-11-03

申请号：US12916061

申请日：2010-10-29

申请人： Matthew Yurek ,  Hansen Yuan ,  Anthony Yeung ,  Craig Litherland ,  Kurt Veeder ,  Robert Huffman

发明人： Matthew Yurek ,  Hansen Yuan ,  Anthony Yeung ,  Craig Litherland ,  Kurt Veeder ,  Robert Huffman

IPC分类号： A61F2/44

CPC分类号： A61F2/441 ,  A61B17/04 ,  A61B17/064 ,  A61B17/842 ,  A61B17/86 ,  A61B17/869 ,  A61F2/28 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30092 ,  A61F2002/302 ,  A61F2002/30235 ,  A61F2002/30462 ,  A61F2002/3052 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30601 ,  A61F2002/30616 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2002/4629 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0085 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2310/00011 ,  A61F2310/00353 ,  A61F2310/00365

摘要： The present invention relates to a device and method to perform 1) disc fusion, 2) artificial replacement of the nucleus, 3) artificial replacement of the annulus, or 4) artificial replacement of both the nucleus and annulus. The device is designed to be placed into the intervertebral space following discectomy. The invention includes a delivery catheter and an substantially fixed sized mesh loop with a lumen within the mesh loop and a center hole. The mesh loop partially self expands diametrically in diameter upon removal of the introducer sheath and can be further expanded by mechanical means.

摘要翻译： 本发明涉及一种执行1）盘融合的装置和方法，2）人造置换核，3）人造置换环，或4）人造置换核和环。 该装置被设计成放置在椎间盘切除术后的椎间隙中。 本发明包括输送导管和基本上固定尺寸的网状环，其具有网状环内的内腔和中心孔。 网状环在去除引导器护套时部分自身直径扩大，并可通过机械手段进一步扩大。

公开(公告)号：US20100004751A1

公开(公告)日：2010-01-07

申请号：US12541931

申请日：2009-08-15

申请人： Jerome Segal ,  Matthew Yurek

发明人： Jerome Segal ,  Matthew Yurek

IPC分类号： A61F2/44

CPC分类号： A61F2/441 ,  A61B17/04 ,  A61B17/064 ,  A61B17/842 ,  A61B17/86 ,  A61B17/869 ,  A61F2/28 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30092 ,  A61F2002/302 ,  A61F2002/30235 ,  A61F2002/30462 ,  A61F2002/3052 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30601 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2002/4629 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0085 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2310/00011 ,  A61F2310/00353 ,  A61F2310/00365

摘要： The present invention relates to a device and method to 1) facilitate disk fusing, 2) perform an artificial replacement of the nucleus, 3) perform an artificial replacement of the annulus, or 4, perform an artificial replacement of both the nucleus and annulus. The device is designed to be placed into the inter-vertebral space following diskectomy. The invention includes a delivery catheter and an expandable continuous mesh loop that has a torus configuration with a lumen within the mesh and a central hole. The mesh loop can be diametrically increased or contracted in diameter by the control element acting on the mesh loop. The mesh loop may be formed of a woven or braided material for a polymer such as PEEK (polyetheretherketone), nylon, polyurethane, polyester, polyethylene, polypropylene or any other biocompatible polymer, or formed from a metallic braid of stainless steel, Elgiloy, Nitinol, or any other biocompatible metal.

摘要翻译： 本发明涉及一种便于光盘定影的装置和方法，2）进行核的人造置换，3）进行环形的人工置换，或4，对核和环进行人造置换。 该装置被设计成在椎间盘切除术后置于脊椎间隙内。 本发明包括输送导管和可扩张的连续网状环，其具有环形构型，其具有网内的内腔和中心孔。 通过作用在网状环上的控制元件，网状环直径可以直径增加或收缩。 网状环可以由用于聚合物例如PEEK（聚醚醚酮），尼龙，聚氨酯，聚酯，聚乙烯，聚丙烯或任何其它生物相容性聚合物的编织或编织材料形成，或由不锈钢金属编织物Elgiloy，镍钛诺 ，或任何其他生物相容性金属。

公开(公告)号：US20100004750A1

公开(公告)日：2010-01-07

申请号：US12541930

申请日：2009-08-15

申请人： Jerome Segal ,  Matthew Yurek

发明人： Jerome Segal ,  Matthew Yurek

IPC分类号： A61F2/44

CPC分类号： A61F2/441 ,  A61B17/04 ,  A61B17/064 ,  A61B17/842 ,  A61B17/86 ,  A61B17/869 ,  A61F2/28 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30092 ,  A61F2002/302 ,  A61F2002/30235 ,  A61F2002/30462 ,  A61F2002/3052 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30601 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2002/4629 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0085 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2310/00011 ,  A61F2310/00353 ,  A61F2310/00365

摘要： The present invention relates to a device and method to 1) facilitate disk fusing, 2) perform an artificial replacement of the nucleus, 3) perform an artificial replacement of the annulus, or 4, perform an artificial replacement of both the nucleus and annulus. The device is designed to be placed into the inter-vertebral space following diskoctomy. The invention includes a delivery catheter and an expandable continuous mesh loop that has a torus configuration with a lumen within the mesh and a central hole. The mesh loop can be diametrically increased or contracted in diameter by the control element acting on the mesh loop. The mesh loop may be formed of a woven or braided material for a polymer such as PEEK (polyetheretherketone), nylon, polyurethane, polyester, polyethylene, polypropylene or any other biocompatible polymer, or formed from a metallic braid of stainless steel, Elgiloy, Nitinol, or any other biocompatible metal.

摘要翻译： 本发明涉及一种便于光盘定影的装置和方法，2）进行核的人造置换，3）进行环形的人工置换，或4，对核和环进行人造置换。 该装置设计为放置在椎间盘切除术后的椎间空间中。 本发明包括输送导管和可扩张的连续网状环，其具有环形构型，其具有网内的内腔和中心孔。 通过作用在网状环上的控制元件，网状环直径可以直径增加或收缩。 网状环可以由用于聚合物例如PEEK（聚醚醚酮），尼龙，聚氨酯，聚酯，聚乙烯，聚丙烯或任何其它生物相容性聚合物的编织或编织材料形成，或由不锈钢金属编织物Elgiloy，镍钛诺 ，或任何其他生物相容性金属。

公开(公告)号：US20060287730A1

公开(公告)日：2006-12-21

申请号：US11359335

申请日：2006-02-22

申请人： Jerome Segal ,  Matthew Yurek ,  Hansen Yurek ,  Anthony Yeung

发明人： Jerome Segal ,  Matthew Yurek ,  Hansen Yurek ,  Anthony Yeung

IPC分类号： A61F2/44 ,  A61F2/46

CPC分类号： A61F2/441 ,  A61B17/04 ,  A61B17/064 ,  A61B17/842 ,  A61B17/86 ,  A61B17/869 ,  A61B2017/0647 ,  A61B2017/0649 ,  A61F2/28 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30062 ,  A61F2002/30075 ,  A61F2002/30092 ,  A61F2002/302 ,  A61F2002/30235 ,  A61F2002/30462 ,  A61F2002/3052 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30601 ,  A61F2002/4415 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/4495 ,  A61F2002/4627 ,  A61F2002/4629 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0061 ,  A61F2210/0085 ,  A61F2220/0025 ,  A61F2220/0075 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2310/00011 ,  A61F2310/00353 ,  A61F2310/00359 ,  A61F2310/00365

摘要： The present invention relates to a device and method which may be used to reinforce the native annulus during spinal surgery. The device is a catheter based device which is placed into the inter-vertebral space following discectomy performed by either traditional surgical or endoscopic approaches. The distal end of the catheter is comprised of an expansile loop which may be increased in diameter by advancement of a portion of the catheter via its proximal end, such proximal end remaining external to the body. The expansile loop may be formed such that when the loop is diametrically contracted the loop feeds into its other end, similar to a snake eating its own tail. Stabilization of the outer portion of the loop and pulling out the inner portion will thereby increase the overall diameter of the loop while maintaining it as a closed loop or torus. The expansile loop can use an attachment means to secure it to substantially healthy tissues of the annulus, nucleus, or endplates. The present invention comprises four embodiments and can be used to 1) facilitate disk fusing, 2) perform an artificial replacement of the nucleus, 3) perform an artificial replacement of the annulus, or 4, perform an artificial replacement of both the nucleus and annulus.

摘要翻译： 本发明涉及可用于在脊柱手术期间加强天然环的装置和方法。 该装置是基于导管的装置，其通过传统的手术或内窥镜方法进行椎间盘切除术后放置在脊椎间隙内。 导管的远端包括可膨胀的环，其可以通过导管的一部分的近端前进而直径增加，这样的近端保持在身体外部。 可以形成膨胀环，使得当环径向收缩时，环进入其另一端，类似于吃自己的尾巴的蛇。 因此，环路的外部部分的稳定和拉出内部部分将由此增加环路的总直径，同时将其保持为闭环或环面。 扩张环可以使用附着手段将其固定到环状物，细胞核或终板的基本上健康的组织。 本发明包括四个实施例，并且可以用于1）促进磁盘定影，2）进行人造核替换，3）进行环形的人工置换，或4，进行核和环的人造置换 。