摘要:
An optical disc drive device has an FE signal generator which generates a focus error signal, a TE signal generator which generates a tracking error signal, a return beam detector which detects a return beam reflected by an optical disc after irradiated by an optical pickup to generate a return beam level signal, a return beam gain setting part which sets amplitude adjustment amount of the return beam level signal so that a signal level of the return beam level signal generated by the return beam detector coincides with a predetermined reference level, an FE gain setting part which sets amplitude adjustment amount of the focus error signal in accordance with the signal level of the return beam level signal adjusted by the return beam gain setting part so that a signal amplitude of the focus error signal is constant, and a TE gain setting part which sets amplitude adjustment amount of the tracking error signal in accordance with the signal level of the return beam level signal adjusted by the return beam gain adjustment part so that a signal amplitude of the tracking error signal is constant.
摘要:
A cyclic tertiary amine compound which is capable of inhibiting the production of inflammatory cytoines. The compound having a structure represented by the following formula (I): wherein A represents an optionally substituted trivalent group which is benzene, pyrimidine, pyrrole, pyridine, pyridazine, furan, thiopene, pyrazole, imidazole, isoxazole or isothiazole; R1 represents an aryl or a heteroaryl group, which is unsubstituted or substituted; R2 represents a heteroaryl group which is unsubtituted or substituted; and R3 represents a cyclic tertiary amino group, or a pharmacologically acceptable salt of the compound.
摘要翻译:能够抑制炎性细胞因子产生的环状叔胺化合物。 具有由下式(I)表示的结构的化合物:其中A表示任选取代的三价基团,其为苯,嘧啶,吡咯,吡啶,哒嗪,呋喃,噻吩,吡唑,咪唑,异恶唑或异噻唑; R 1表示未取代或取代的芳基或杂芳基; R 2表示未取代或取代的杂芳基; R 3表示化合物的环状叔氨基或药理学上可接受的盐。
摘要:
Compounds having activity against production of an inflammatory cytokine of formula (I)′: A′ is pyrrole; R1′ is phenyl or naphthyl; R2′ is pyridyl or pyrimidinyl; R3′ is (IIa)′, (IIb)′ or (IIc)′: m′ is 1; E′ is nitrogen; D′ is >C(R5′), R5′ is hydrogen, Substituent α′ or Substituent β′; B′ is nitrogen-containing 5-membered heterocyclic; R4′ is 1 to 3 substituents from Substituent α′, Substituent β′ and Substituent γ′; R1′ and R3′ are bonded to two atoms of the pyrrole adjacent to the pyrrole atom bonded to R2′; Substituent α′ is hydroxyl, nitro, cyano, halogen, alkoxy, halogeno alkoxy, alkylthio, halogeno alkylthio or —NRa′Rb′; Ra′ and Rb′ are hydrogen, alkyl, alkenyl, alkynyl, aralkyl or alkylsulfonyl, or Ra′ and Rb′ with the nitrogen atom form a heterocyclyl; Substituent β′ is alkyl, alkenyl, alkynyl, aralkyl or cycloalkyl; Substituent γ′is oxo, hydroxyimino, alkoxyimino, alkylene, alkylenedioxy, alkylsulfinyl, alkylsulfonyl, aryl, aryloxy, alkylidenyl or aralkylidenyl.
摘要翻译:具有抗式产生式(I)的炎性细胞因子的活性化合物的化合物:A'是吡咯; R 1是苯基或萘基; R 2是吡啶基或嘧啶基; (IIa)',(IIb)'或(IIc)':m'为1; E'是氮; D'是> C(R 5'),R 5'是氢,取代基α'或取代基β'; B'是含氮5元杂环; R 4'是1至3个取代基α',取代基β'和取代基γ'的取代基; R 1'和R 3'连接到与R 2'连接的吡咯原子相邻的吡咯的两个原子上; 取代基α'是羟基,硝基,氰基,卤素,烷氧基,卤代烷氧基,烷硫基,卤代烷硫基或-NR a R b B。 R a,O和R b'是氢,烷基,烯基,炔基,芳烷基或烷基磺酰基,或者R a'和R“ b'与氮原子形成杂环基; 取代基β'是烷基,烯基,炔基,芳烷基或环烷基; 取代基γ'是氧代,羟基亚氨基,烷氧基亚氨基,亚烷基,亚烷基二氧基,烷基亚磺酰基,烷基磺酰基,芳基,芳氧基,亚烷基或芳亚烷基。
摘要:
The invention provides a novel apparatus for manufacturing electronic parts each incorporating a plurality of lead wires fully wrapped with conductive foil like noise filters for example. A turn table is intermittently shifted from the first work station to the seventh work station in the state in which an individual-unit lead-wire member is retained by a holding unit on the turn table. A predetermined lead wire is folded by respective work stations, whereas the remaining lead wires are adhered with conductive foil tapes via spot-welding process, and then these lead wires are fully wrapped with conductive foil tapes. Next, the predetermined lead wire is restored to the initial posture, and then all the lead wires are fully wrapped with insulation tapes. In this way, all the lead wires are properly processed so that they can be integrated in perfect alignment with constant pitches.
摘要:
Compounds exhibiting calcium receptor antagonist activity that are safe and orally administrable having Formula (I) or pharmaceutically acceptable salts thereof
摘要:
An automatic power control filter circuit that outputs a signal corrected to make a laser drive current for driving a laser light emitting element irradiating an optical disc with a laser beam become a desired value, on the basis of a signal obtained by sampling and holding a light emission monitor signal corresponding to an output current of a photodetector for detecting output power of the laser light emitting element.
摘要:
Novel compounds represented by the following formula (I) that act as a ligand to sigma receptor/binding cite and a medicament comprising the same as an active ingredient: wherein X represents an alkyl group, an aryl group, a heterocyclic group or the like; Q represents a group represented by —CH2—, —CO—, —O—, —CH(OR7)— or the like wherein R7 represents a hydrogen atom, an alkyl group or the like; n represents an integer of from 0 to 5; R1 and R2 each represent a hydrogen atom, an alkyl group or the like; B represents either of the following groups: wherein R3, R4, R5, and R6 each represent a hydrogen atom, a halogen atom, an alkoxyl group or the like; m represents 1 or 2; and the ring of: represents an aromatic heterocyclic ring.
摘要:
The present invention provides a photochromic compound oxide of Ti, Fe and Si which may contain Al and a cosmetic comprising the above photochromic compound oxide which, even when a light quantity change instantaneously occurs as in taking a photographic picture with the use of flashlight, exhibits satisfactory changes in lightness and color difference in accordance with the above instantaneous light quantity change.
摘要:
The present invention is directed to a method of stimulating superoxide generation using phenolic thioethers which stimulate the generation of superoxide.
摘要:
The present invention relates to a method of inhibiting superoxide generation which comprises administering to a mammal in need of such treatment an amount of a compound of the Formula I ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and independently represent tert-alkyl or phenyl; Alk.sup.1 represents straight or branched chain alkylene of 1 to 10 carbon atoms, X represents sulfur or oxygen, Alk.sup.2 represents straight or branched chain alkylene of 1 to 4 carbon atoms; and m is 0, 1 or 2; or a pharmaceutically acceptable salt or stereoisomer or geometric isomer thereof, which is effective to inhibit superoxide generation.