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公开(公告)号:US20090203100A1
公开(公告)日:2009-08-13
申请号:US12296300
申请日:2007-04-05
摘要: The present invention relates to methods for increasing the efficiency of anaerobic fermentation processes (1) that produce acetate as a by-product in addition to a desired product, and (2) that can utilise hydrogen and/or carbon dioxide in the fermentation. The method comprises the steps of converting acetate produced by the fermentation process into hydrogen gas and carbon dioxide gas, and utilising hydrogen gas and/or carbon dioxide gas obtained from the acetate conversion in the anaerobic fermentation process. In particular aspects, the invention relates to processes of producing alcohols, particularly ethanol.
摘要翻译: 本发明涉及提高厌氧发酵方法(1)的效率的方法(1),除了所需产物外,还可以生产作为副产物的乙酸酯,和(2)可以在发酵中利用氢和/或二氧化碳。 该方法包括以下步骤:将通过发酵过程产生的乙酸转化为氢气和二氧化碳气体,并在厌氧发酵过程中利用由乙酸酯转化得到的氢气和/或二氧化碳气体。 在具体方面,本发明涉及生产醇,特别是乙醇的方法。
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公开(公告)号:US08376736B2
公开(公告)日:2013-02-19
申请号:US12739424
申请日:2008-10-23
申请人: Sean Dennis Simpson , Christophe Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley
发明人: Sean Dennis Simpson , Christophe Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley
CPC分类号: C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要: The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.
摘要翻译: 本发明涉及通过包含CO的气态底物的微生物发酵来捕获碳的方法。本发明的方法包括将CO转化为一种或多种包括醇和/或酸的产物,并任选地捕获CO 2以改善总体碳捕获。 在某些方面,本发明涉及从工业废物流,特别是炼钢厂废气中生产醇,特别是乙醇的方法。
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公开(公告)号:US20100317074A1
公开(公告)日:2010-12-16
申请号:US12739424
申请日:2008-10-23
申请人: Sean Dennis Simpson , Christopher Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley
发明人: Sean Dennis Simpson , Christopher Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley
CPC分类号: C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要: The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.
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公开(公告)号:US20100311104A1
公开(公告)日:2010-12-09
申请号:US12742149
申请日:2008-11-13
申请人: Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Phuong Tran , Matthew James Rowe , Ian Linstrand Warner
发明人: Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Phuong Tran , Matthew James Rowe , Ian Linstrand Warner
CPC分类号: C12R1/145 , B01D53/62 , B01D53/73 , B01D53/84 , B01D2251/95 , B01D2257/504 , C10J2300/0916 , C10J2300/0956 , C10J2300/1681 , C12P7/065 , C12P7/54 , Y02A50/2341 , Y02A50/2358 , Y02C10/02 , Y02C10/04 , Y02E50/17 , Y02P20/152
摘要: A novel class of bacteria is described which has improved efficiency in the production of thanol by anaerobic fermentation of substrates containing carbon monoxide.
摘要翻译: 描述了一类新颖的细菌,其通过含有一氧化碳的底物的厌氧发酵提高了生产的效率。
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公开(公告)号:US08703127B2
公开(公告)日:2014-04-22
申请号:US13350480
申请日:2012-01-13
IPC分类号: C12P21/06 , A61K39/395
CPC分类号: G01N33/57434
摘要: Methods for diagnosing the presence of prostate cancer in a subject are provided, such methods including detecting the levels of expression of multiple polypeptide biomarkers in a biological sample obtained from the subject and comparing the levels of expression with predetermined threshold levels. Levels of expression of at least two of the polypeptide markers that are above the predetermined threshold levels are indicative of the presence of prostate cancer in the subject. Determination of the expression levels of specific combinations of biomarkers can also be used to determine the type and/or stage of prostate cancer.
摘要翻译: 提供了用于诊断受试者中前列腺癌存在的方法,所述方法包括检测从受试者获得的生物样品中多种多肽生物标志物的表达水平,并将表达水平与预定阈值水平进行比较。 高于预定阈值水平的至少两种多肽标记物的表达水平指示受试者中前列腺癌的存在。 确定生物标志物的特定组合的表达水平也可用于确定前列腺癌的类型和/或阶段。
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公开(公告)号:US08383376B2
公开(公告)日:2013-02-26
申请号:US13587444
申请日:2012-08-16
申请人: Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Simon David Oakley , Michael Charles Milner Cockrem , Michael Koepke
发明人: Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Simon David Oakley , Michael Charles Milner Cockrem , Michael Koepke
CPC分类号: C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要: The invention relates to processes for converting CO by microbial fermentation to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. More particularly the invention relates to a method for producing one or more products from a CO comprising substrate, the method comprising a natural gas reforming step for producing a syngas stream, and converting at least a portion of CO from the syngas stream to one or more products including ethanol.
摘要翻译: 本发明涉及通过微生物发酵将CO转化为一种或多种产品(包括醇和/或酸)并任选地捕获CO 2以改善总体碳捕获的方法。 更具体地说,本发明涉及从包含CO的底物生产一种或多种产品的方法,所述方法包括用于产生合成气流的天然气重整步骤,以及将来自合成气流的至少一部分CO转化为一种或多种 产品包括乙醇。
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公开(公告)号:US08119844B2
公开(公告)日:2012-02-21
申请号:US12428829
申请日:2009-04-23
CPC分类号: C07C29/74 , C12P7/16 , Y02E50/10 , C07C31/225
摘要: The invention relates to methods for the production of alcohols by microbial fermentation, particularly microbial fermentation of substrates comprising glycerol and/or acetate, to butanol.
摘要翻译: 本发明涉及通过微生物发酵生产醇的方法,特别是包含甘油和/或乙酸酯的底物至丁醇的微生物发酵方法。
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公开(公告)号:US08852918B2
公开(公告)日:2014-10-07
申请号:US13537798
申请日:2012-06-29
申请人: Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Phuong Loan Tran , Matthew James Rowe , Ian Linstrand Warner
发明人: Sean Dennis Simpson , Richard Llewellyn Sydney Forster , Phuong Loan Tran , Matthew James Rowe , Ian Linstrand Warner
CPC分类号: C12R1/145 , C12N1/20 , C12P7/065 , C12P7/08 , C12P7/54 , Y02E50/17 , Y10S435/821 , Y10S435/842
摘要: A biologically pure isolate of a selected bacterium derived from Clostridium autoethanogenum is described which has improved efficiency in the production of ethanol by anaerobic fermentation of substrates comprising carbon monoxide. The bacterium can produce ethanol and acetate at an ethanol to acetate ratio of at least 1.0 and has a productivity of at least 1.2 g of ethanol/l of fermentation broth per day. The bacterium is also characterized in that it has substantially no ability to sporulate.
摘要翻译: 描述了一种来源于自发性梭菌(Clostridium autoethanogenum)的选定细菌的生物纯的分离物,其通过包含一氧化碳的底物的厌氧发酵而提高了乙醇生产的效率。 该细菌可以以至少1.0的乙醇与乙酸酯比率生产乙醇和乙酸盐,并且每天产生至少1.2g乙醇/ l的发酵液。 细菌的特征还在于其基本上不具有孢子形成能力。
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公开(公告)号:US08507228B2
公开(公告)日:2013-08-13
申请号:US12821468
申请日:2010-06-23
申请人: Sean Dennis Simpson , Christophe Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley , Michael Kopke
发明人: Sean Dennis Simpson , Christophe Collet , Richard Llewellyn Sydney Forster , Michael Charles Milner Cockrem , Simon David Oakley , Michael Kopke
IPC分类号: A61L9/01 , C02F3/00 , C02F3/34 , C12P1/04 , C12P7/00 , C12P7/02 , C12P7/04 , C12P7/06 , C12P7/08 , C12P7/40 , C12P7/54 , C12P7/62
CPC分类号: C12P7/28 , C01B3/38 , C01B2203/0233 , C01B2203/0255 , C01B2203/0261 , C01B2203/0405 , C01B2203/0415 , C01B2203/043 , C01B2203/0475 , C01B2203/06 , C01B2203/1058 , C01B2203/86 , C12M21/12 , C12M29/26 , C12M41/34 , C12M43/04 , C12P1/04 , C12P7/00 , C12P7/065 , C12P7/08 , C12P7/54 , C12P7/62 , Y02E50/17 , Y02E50/343 , Y02P30/30 , Y02W10/37
摘要: The invention relates to methods of capturing carbon by microbial fermentation of a gaseous substrate comprising CO. The methods of the invention include converting CO to one or more products including alcohols and/or acids and optionally capturing CO2 to improve overall carbon capture. In certain aspects, the invention relates to processes for producing alcohols, particularly ethanol, from industrial waste streams, particularly steel mill off-gas.
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公开(公告)号:US20130116133A1
公开(公告)日:2013-05-09
申请号:US13350480
申请日:2012-01-13
CPC分类号: G01N33/57434
摘要: Methods for diagnosing the presence of prostate cancer in a subject are provided, such methods including detecting the levels of expression of multiple polypeptide biomarkers in a biological sample obtained from the subject and comparing the levels of expression with predetermined threshold levels. Levels of expression of at least two of the polypeptide markers that are above the predetermined threshold levels are indicative of the presence of prostate cancer in the subject. Determination of the expression levels of specific combinations of biomarkers can also be used to determine the type and/or stage of prostate cancer.
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