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公开(公告)号：US20140341816A1
公开(公告)日：2014-11-20
申请号：US14365113
申请日：2011-12-16
CPC分类号： A61K49/00 , A61K8/0204 , A61K8/0233 , A61K8/345 , A61K8/4993 , A61K8/731 , A61K8/732 , A61K2800/43 , A61Q11/00 , B65D35/00
摘要： Described herein are dentifrices comprising a first formulation and a second formulation, wherein the formulations are coaxially extruded, so that the first formulation enrobes the second formulation, wherein the first formulation is opaque and wherein the second formulation comprises dissolvable film fragments, together with methods of making and using the same and containers for providing the same.
摘要翻译： 本文描述的是包含第一制剂和第二制剂的洁齿剂，其中所述制剂被同轴挤出，使得第一制剂对第二制剂进行了刺激，其中第一制剂是不透明的，其中第二制剂包含可溶性膜片段， 使用和使用相同的容器提供相同的容器。
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公开(公告)号：US20140322141A1
公开(公告)日：2014-10-30
申请号：US14365116
申请日：2011-12-16
CPC分类号： A61K8/58 , A61K8/02 , A61K8/0216 , A61K8/494 , A61K8/731 , A61K2800/43 , A61K2800/58 , A61Q11/00
摘要： Described herein are compositions comprising a film, wherein the film comprises a pigment, and is adapted to release the pigment at a specific point in time during use; and methods of making and using the same.
摘要翻译： 本文描述的是包含膜的组合物，其中所述膜包含颜料，并且适于在使用期间在特定时间点释放颜料; 以及制作和使用它们的方法。
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公开(公告)号：US10959967B2
公开(公告)日：2021-03-30
申请号：US12866609
申请日：2009-02-06
申请人： Rajnish Kohli , Richard Scott Robinson , Ralph Peter Santarpia, III , James R. Brown , Richard J. Sullivan , Michael Prencipe
发明人： Rajnish Kohli , Richard Scott Robinson , Ralph Peter Santarpia, III , James R. Brown , Richard J. Sullivan , Michael Prencipe
摘要： The present invention is directed to effervescent compositions comprising a basic amino acid.
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公开(公告)号：US09855200B2
公开(公告)日：2018-01-02
申请号：US13266938
申请日：2010-05-26
CPC分类号： A61K8/27 , A61K8/345 , A61K8/73 , A61K8/731 , A61K8/8164 , A61K8/86 , A61K2800/56 , A61K2800/592
摘要： An oral care composition and method are described in which the composition includes a film or a plurality of film fragments entrained in a carrier. The film or plurality of film fragments comprises a zinc compound and the carrier comprises a polysaccharide and a maleic anhydride copolymer. The composition and methods provide benefits including one or more of increased consumer acceptability, improved solubility of zinc thus permitting the use of lower amounts of zinc compounds and reducing the adverse astringency associated with zinc, decreased adverse reactions brought about by the presence of zinc ions, enhanced aesthetics, improved stability for active or other functional materials, and controlled delivery of active materials such as zinc.
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公开(公告)号：US09682027B2
公开(公告)日：2017-06-20
申请号：US12058424
申请日：2008-03-28
申请人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
发明人： Michael Prencipe , Diane Cummins , Richard Scott Robinson , Sarita V. Mello , Richard J. Sullivan , Suman Chopra , Karen J. DePierro , Lynette Zaidel , Constantina Christopoulou , Ravi Subramanyam , Donghui Wu , Andre M. Morgan , Ralph Peter Santarpia, III , Qin Wang , Gary Edward Tambs , Rajnish Kohli , Virginia Monsul Barnes , Sergio Leite , Eric A. Simon
CPC分类号： A61K8/44 , A61K8/25 , A61K31/198 , A61Q11/00
摘要： This invention relates to oral care compositions comprising a basic amino acid or salt thereof, and a small particle fraction: and to methods of using and of making these compositions.
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公开(公告)号：US09072672B2
公开(公告)日：2015-07-07
申请号：US11168681
申请日：2005-06-28
CPC分类号： A61K8/19 , A61K8/24 , A61K8/26 , A61K8/29 , A61K8/8111 , A61K8/8123 , A61K8/8152 , A61Q11/00
摘要： Compositions for altering the color of teeth, including tooth-coating compositions comprising a colorant and an acrylate polymer. Colorants among those useful herein include whiteness-imparting particulate materials, such as hydroxyapatite.
摘要翻译： 用于改变牙齿颜色的组合物，包括包含着色剂和丙烯酸酯聚合物的牙齿涂层组合物。 可用于本文的着色剂包括赋予白度的颗粒材料，例如羟基磷灰石。
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公开(公告)号：US20140314690A1
公开(公告)日：2014-10-23
申请号：US14365187
申请日：2011-12-20
申请人： Steven Fisher , Mary Colligan , Michael Prencipe , Gary Tambs
发明人： Steven Fisher , Mary Colligan , Michael Prencipe , Gary Tambs
摘要： Described herein are preservative systems which prevent the growth of microorganisms in silica based dentifrices, compositions comprising the same; and methods of making and using the same.
摘要翻译： 本文描述了防止微生物在二氧化硅基洁牙剂中生长的防腐剂体系，包含它们的组合物; 以及制作和使用它们的方法。
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公开(公告)号：US08815215B2
公开(公告)日：2014-08-26
申请号：US10915125
申请日：2004-08-10
CPC分类号： A61K8/89 , A61C19/066 , A61K8/22 , A61K8/8176 , A61K8/891 , A61K8/895 , A61Q11/00
摘要： A tooth whitening system comprising a dental tray having a surface operable to confront a tooth surface, and a tooth whitening composition comprising a whitening agent and a hydrophobic polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. A tooth whitening kit is also provided using a dental tray and the tooth whitening composition comprising a whitening composition and a hydrophobic polymer carrier.
摘要翻译： 一种牙齿美白系统，其包括具有可操作以面对牙齿表面的表面的牙托盘，和包含增白剂和疏水性聚合物载体的牙齿增白组合物。 牙齿美白组合物优选基本上是非水溶性的。 还使用牙科托盘和含有美白组合物和疏水性聚合物载体的牙齿增白组合物来提供牙齿美白试剂盒。
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公开(公告)号：US08652495B2
公开(公告)日：2014-02-18
申请号：US13637370
申请日：2010-03-31
申请人： Venda Porter , Andre Morgan , Michael Prencipe
发明人： Venda Porter , Andre Morgan , Michael Prencipe
IPC分类号： A61K8/02
CPC分类号： A61K8/27 , A61K8/0245 , A61K8/19 , A61K8/29 , A61K8/44 , A61K8/731 , A61K2800/412 , A61K2800/5922 , A61K2800/594 , A61K2800/624 , A61Q11/00
摘要： Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.
摘要翻译： 公开了口腔护理组合物，例如洁牙剂组合物，其包含口腔护理组合物，其包含口腔可接受的载体，平均粒度不大于牙本质小管的金属氧化物颗粒和能够螯合金属氧化物的至少一种氨基酸。 组合物可以包含用于将金属氧化物颗粒粘附在牙本质小管中的聚合物粘附材料。 金属氧化物颗粒的中值粒径为5微米以下，可以含有氧化锌。
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20.发明申请LOW WATER STANNOUS FLUORIDE PLUS ZINC CITRATE DENTIFRICE WITH IMPROVED STABILITY, RHEOLOGY, AND EFFICACY 有权低水稳定性氟化物加锌盐酸盐，具有改善的稳定性，流变性和有效性公开(公告)号：US20120207686A1
公开(公告)日：2012-08-16
申请号：US13503801
申请日：2009-10-29
申请人： Linh Fruge , Steven Wade Fisher , Michael Prencipe
发明人： Linh Fruge , Steven Wade Fisher , Michael Prencipe
CPC分类号： A61Q11/00 , A61K8/20 , A61K8/24 , A61K8/365 , A61K2800/31
摘要： A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.
摘要翻译： 具有低水相的洁齿剂组合物，其含有有效量的多磷酸盐和离子活性成分。
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