公开(公告)号：US20240261561A1

公开(公告)日：2024-08-08

申请号：US18632569

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/178 ,  A61M60/226 ,  A61M60/419 ,  A61M60/531 ,  A61M60/538 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC classification number: A61M60/178 ,  A61M60/226 ,  A61M60/419 ,  A61M60/531 ,  A61M60/538 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more blood-outlet openings and including a narrower section, and a wider section, which is proximal to and wider than the narrower section, and which is shaped to define at least a portion of each of the blood-outlet openings such that a normal vector to the portion has a distally-facing component. The pump-outlet tube is inserted, through the subject's aorta, into the subject's left ventricle such that the pump-outlet tube traverses an aortic valve of the subject with the blood-outlet openings being disposed within the aorta. An impeller is disposed within the narrower section of the pump-outlet tube and is configured to pump blood of the subject, through the blood-outlet openings, from the left ventricle into the aorta. Other applications are also described.

公开(公告)号：US20250073446A1

公开(公告)日：2025-03-06

申请号：US18933749

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/216 ,  A61M60/17 ,  A61M60/414 ,  A61M60/825 ,  A61M60/90

Abstract: Apparatus and methods are described including a solid axial shaft having a shaft diameter that is less than 0.8 mm, an impeller configured for insertion into a left ventricle of a heart of a subject and coupled to the axial shaft, and a hollow drive cable coupled, at a distal end of the drive cable, to the axial shaft, and configured to rotate so as to rotate the axial shaft, thereby causing the impeller to pump blood of the subject from the left ventricle. Other applications are also described.

公开(公告)号：US20250065104A1

公开(公告)日：2025-02-27

申请号：US18933729

申请日：2024-10-31

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/808 ,  A61M60/13 ,  A61M60/237

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a subject's body. The blood pump also includes an impeller, which includes a proximal bushing disposed over the axial shaft, a distal bushing disposed over the axial shaft distally from the proximal bushing, and one or more blades. Each of the blades includes a single inner helical elongate element, a single outer helical elongate element, and a film of material extending between the inner helical elongate element and the outer helical elongate element. The blades are proximally coupled to the proximal bushing and distally coupled to the distal bushing such that, as the axial shaft rotates, the blades rotate, thereby pumping blood of the subject. Other applications are also described.

公开(公告)号：US20240269457A1

公开(公告)日：2024-08-15

申请号：US18640222

申请日：2024-04-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/17 ,  A61M60/13 ,  A61M60/414 ,  A61M60/554 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81

CPC classification number: A61M60/17 ,  A61M60/13 ,  A61M60/414 ,  A61M60/554 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3303 ,  A61M2205/3331 ,  A61M2205/502 ,  A61M2210/125 ,  A61M2230/30

Abstract: Apparatus and methods are described including a device configured for insertion into a left ventricle of a heart of a subject. A delivery tube is coupled to the device and configured to traverse an aortic arch of the subject while the device is within the left ventricle. An elongation-resistant fiber runs axially along the delivery tube so as to bias an orientation of the delivery tube while the delivery tube traverses the aortic arch such that the elongation-resistant fiber is disposed inside a curve of the aortic arch, thereby biasing an orientation of the device. Other applications are also described.

公开(公告)号：US20240261563A1

公开(公告)日：2024-08-08

申请号：US18637655

申请日：2024-04-17

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/414 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825

CPC classification number: A61M60/414 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/806 ,  A61M60/81 ,  A61M60/825 ,  A61M2039/1077

Abstract: Apparatus and methods are described including inserting a drive-cable end of a drive cable, which includes a plurality of coiled wires, and a hollow-shaft end of a hollow shaft, which hollow-shaft end is shaped to define multiple shaft pores, into opposing ends of a coupling tube having a wall shaped to define multiple tabs. The drive cable is coupled to the shaft by pushing at least some of the tabs into the shaft pores, respectively. Other applications are also described.

公开(公告)号：US20240261562A1

公开(公告)日：2024-08-08

申请号：US18635286

申请日：2024-04-15

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/414 ,  A61L29/02 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/857

CPC classification number: A61M60/414 ,  A61L29/02 ,  A61M60/13 ,  A61M60/174 ,  A61M60/242 ,  A61M60/857

Abstract: Apparatus and methods are provided, including inserting a drive-cable-bearing tube, which includes one or more inwardly-facing ceramic portions, into a body of a subject and through an aorta of the subject, such that the inwardly-facing ceramic portions are within an aortic arch of the subject, while a drive cable, which is coupled to an intracorporeal device at a distal end of the drive-cable-bearing tube and includes one or more outwardly-facing ceramic portions, passes through the drive-cable-bearing tube such that the outwardly-facing ceramic portions are aligned with the inwardly-facing ceramic portions. The drive cable is rotated within the drive-cable-bearing tube, thereby rotating the intracorporeal device, while the outwardly-facing ceramic portions are aligned with the inwardly-facing ceramic portions. Other applications are also described.

公开(公告)号：US20250010060A1

公开(公告)日：2025-01-09

申请号：US18889744

申请日：2024-09-19

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61L29/02 ,  A61M39/10 ,  A61M60/13 ,  A61M60/17 ,  A61M60/174 ,  A61M60/178 ,  A61M60/216 ,  A61M60/226 ,  A61M60/237 ,  A61M60/242 ,  A61M60/295 ,  A61M60/408 ,  A61M60/414 ,  A61M60/419 ,  A61M60/497 ,  A61M60/508 ,  A61M60/531 ,  A61M60/538 ,  A61M60/554 ,  A61M60/585 ,  A61M60/806 ,  A61M60/808 ,  A61M60/81 ,  A61M60/816 ,  A61M60/818 ,  A61M60/825 ,  A61M60/829 ,  A61M60/833 ,  A61M60/857 ,  A61M60/859 ,  A61M60/865

Abstract: Apparatus and methods are described including a blood pump that includes a pump-outlet tube shaped to define one or more blood-outlet openings and configured for insertion into a heart of a subject. An impeller is disposed within a distal portion of the pump-outlet tube and is configured to pump blood of the subject proximally through the pump-outlet tube, such that the blood exits the pump-outlet tube through the blood-outlet openings. A delivery tube extends, from outside a body of the subject, through the pump-outlet tube to the distal portion. A drive cable passes through the delivery tube and is configured to rotate the impeller. A proximal portion of the pump-outlet tube includes multiple strips adhered to the delivery tube. Other embodiments are also described.

公开(公告)号：US20240359000A1

公开(公告)日：2024-10-31

申请号：US18639087

申请日：2024-04-18

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/818 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829

CPC classification number: A61M60/818 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/808 ,  A61M60/81 ,  A61M60/829 ,  A61M2205/0211 ,  A61M2205/0222 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/502

Abstract: Apparatus and methods are described including a blood pump that includes an axial shaft configured for insertion into, and rotation within, a body of a subject. An impeller is coupled to the axial shaft such that, as the axial shaft rotates, the impeller pumps blood of the subject. A thrust bearing includes a proximally-facing ceramic surface disposed distally from the axial shaft so as to inhibit distal movement of the axial shaft beyond the thrust bearing, and a distally-facing ceramic cover that covers a distal end of the axial shaft, such that the ceramic cover contacts the ceramic surface as the axial shaft rotates. Other applications are also described.

公开(公告)号：US20240342464A1

公开(公告)日：2024-10-17

申请号：US18632545

申请日：2024-04-11

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/508 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81

CPC classification number: A61M60/90 ,  A61M60/13 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/508 ,  A61M60/585 ,  A61M60/808 ,  A61M60/81 ,  A61M2205/103 ,  A61M2205/502 ,  A61M2210/125

Abstract: Apparatus and methods are described including a left-ventricular assist device that includes a pump-outlet tube shaped to define one or more blood-outlet openings and configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that the pump-outlet tube traverses an aortic valve of the subject with the blood-outlet openings being disposed within the aorta. A blood pump is disposed at least partly within a distal portion of the pump-outlet tube and is configured to pump blood of the subject proximally through the pump-outlet tube. A proximal end of the pump-outlet tube is folded inwardly so as to define one or more surfaces configured to direct the blood through the blood-outlet openings by virtue of being oblique with respect to a longitudinal axis of the pump-outlet tube. Other applications are also described.

公开(公告)号：US20240299733A1

公开(公告)日：2024-09-12

申请号：US18654336

申请日：2024-05-03

Applicant: MAGENTA MEDICAL LTD

Inventor： Yosi TUVAL ,  Gad LUBINSKY ,  Yuri SUDIN ,  Avi ROZENFELD ,  Shaul MUSTACCHI ,  Ran TAMIR

IPC: A61M60/90 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865

CPC classification number: A61M60/90 ,  A61M60/17 ,  A61M60/216 ,  A61M60/414 ,  A61M60/531 ,  A61M60/808 ,  A61M60/818 ,  A61M60/829 ,  A61M60/865 ,  A61M2205/0266 ,  A61M2205/04 ,  A61M2205/103 ,  A61M2205/3303 ,  A61M2205/3327 ,  A61M2205/3331 ,  A61M2205/3365 ,  A61M2205/502 ,  A61M2207/10 ,  A61M2230/30

Abstract: Apparatus and methods are described including an axial shaft and an impeller configured for rotation within a subject's body. A coupling element includes a first portion, which is disposed around the axial shaft, is shaped to define one or more slits that facilitate a radial expansion of the first portion such that the first portion is placeable around the axial shaft, and is shape-set to have an inner diameter that is smaller than a diameter of the axial shaft such that, following placement of the first portion around the axial shaft, the first portion becomes radially contracted around, and thus locked in place with respect to, the axial shaft. A second portion of the coupling element is coupled to a bushing of the impeller. Other applications are also described.