公开(公告)号：US20250043906A1

公开(公告)日：2025-02-06

申请号：US18793305

申请日：2024-08-02

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Manish KOCHAR ,  Gary KRIVOY ,  Aaron H. LEIMKUEHLER

IPC: F16M13/02 ,  F16M11/14 ,  F16M11/20

Abstract: The invention relates to a load support unit for holding and adjusting the orientation of the load. The load support unit includes a lower arm, a upper arm, a mounting swivel, a swivel joint, a knuckle joint and a rotational joint. The mounting swivel allows the load support unit to rotate relative to its surroundings, the swivel joint allows the upper arm to rotate relative to the lower arm, the knuckle joint allows the upper arm to pivot in a rotational direction relative to the lower arm, and the rotational joint allows the load to rotate about the upper arm.

公开(公告)号：US20240280786A1

公开(公告)日：2024-08-22

申请号：US18596909

申请日：2024-03-06

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Ian D. CHAMBERLIN ,  Charles M. CLINTON ,  Eli N. GLEZER ,  Bandele JEFFREY-COKER ,  Manish KOCHAR ,  Sandor KOVACS ,  D.T. LE ,  Aaron LEIMKUEHLER ,  George SIGAL ,  Leo TABAKIN ,  Jon WILLOUGHBY

IPC: G02B7/36 ,  G01N21/25 ,  G01N21/64 ,  G01N35/02

CPC classification number: G02B7/36 ,  G01N21/253 ,  G01N21/6452 ,  G01N35/028

Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.

公开(公告)号：US20220365106A1

公开(公告)日：2022-11-17

申请号：US17679663

申请日：2022-02-24

Applicant: Meso Scale Technologies, LLC.

Inventor： Manish KOCHAR ,  Peter J. BOSCO ,  Ian D. CHAMBERLIN ,  Bandele JEFFREY-COKER ,  Eric M. JONES ,  Gary I. KRIVOY ,  Don E. KRUEGER ,  Aaron H. LEIMKUEHLER ,  Pei-Ming WU ,  Kim-Xuan NGUYEN ,  Pankaj OBEROI ,  Louis W. PANG ,  Jennifer PARKER ,  Victor PELLICIER ,  Nicholas SAMMONS ,  George SIGAL ,  Jacob N. WOHLSTADTER ,  Michael L. VOCK ,  Stanley T. SMITH ,  Carl C. STEVENS ,  Rodger D. OSBORNE ,  Kenneth E. PAGE ,  Michael T. WADE ,  Jon WILLOUGHBY ,  Lei WANG

IPC: G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  G16H40/67 ,  G16H10/40 ,  G16H40/40 ,  F24F11/30 ,  G06K7/14 ,  G06Q10/08 ,  G06Q10/10

Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

公开(公告)号：US20220019053A1

公开(公告)日：2022-01-20

申请号：US17492187

申请日：2021-10-01

Applicant: Meso Scale Technologies, LLC.

Inventor： Ian CHAMBERLIN ,  Charles M. CLINTON ,  Eli N. GLEZER ,  Bandele JEFFREY-COKER ,  Manish KOCHAR ,  Sandor KOVACS ,  D.T. Le ,  Aaron LEIMKUEHLER ,  George SIGAL ,  Leo TABAKIN ,  Jon WILLOUGHBY

IPC: G02B7/36 ,  G01N21/25 ,  G01N21/64 ,  G01N35/02

Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.

公开(公告)号：US20240094233A1

公开(公告)日：2024-03-21

申请号：US18354382

申请日：2023-07-18

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Jacob N. WOHLSTADTER ,  Manish KOCHAR ,  Peter J. BOSCO ,  Ian D. CHAMBERLIN ,  Bandele JEFFREY-COKER ,  Eric M. JONES ,  Gary I. KRIVOY ,  Don E. KRUEGER ,  Aaron H. LEIMKUEHLER ,  Pei-Ming WU ,  Kim-Xuan NGUYEN ,  Pankaj OBEROI ,  Louis W. PANG ,  Jennifer PARKER ,  Victor PELLICIER ,  Nicholas SAMMONS ,  George SIGAL ,  Michael L. VOCK ,  Stanley T. SMITH ,  Carl C. STEVENS ,  Rodger D. OSBORNE ,  Kenneth E. PAGE ,  Michael T. WADE ,  Jon WILLOUGHBY ,  Lei WANG ,  Xinri CONG ,  Kin NG

IPC: G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  F24F11/30 ,  G06K7/14 ,  G06Q10/087 ,  G06Q10/10 ,  G16H10/40 ,  G16H40/40 ,  G16H40/67

CPC classification number: G01N35/0099 ,  B01L3/50853 ,  B01L9/523 ,  F24F11/30 ,  G06K7/1413 ,  G06Q10/087 ,  G06Q10/10 ,  G16H10/40 ,  G16H40/40 ,  G16H40/67 ,  B01L2200/143 ,  B01L2300/021 ,  G01N2035/00356 ,  G05B2219/40269 ,  H04B1/3827

Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

公开(公告)号：US20240003925A1

公开(公告)日：2024-01-04

申请号：US18323082

申请日：2023-05-24

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Manish KOCHAR ,  Peter J. BOSCO ,  Ian D. CHAMBERLIN ,  Bandele JEFFREY-COKER ,  Eric M. JONES ,  Gary I. KRIVOY ,  Aaron H. LEIMKUEHLER ,  Pei-Ming WU ,  Kim-Xuan NGUYEN ,  Pankaj OBEROI ,  Louis W. PANG ,  Jennifer PARKER ,  Victor PELLICIER ,  Nicholas SAMMONS ,  George SIGAL ,  Jacob N. WOHLSTADTER ,  Michael L. VOCK ,  Stanley Todd SMITH ,  Carl C. STEVENS ,  Rodger D. OSBORNE ,  Kenneth E. PAGE ,  Michael T. WADE ,  Jon WILLOUGHBY ,  Lei WANG ,  Don E. KRUEGER

IPC: G01N35/00 ,  B01L3/00 ,  B01L9/00 ,  G16H40/67 ,  G16H10/40 ,  G16H40/40 ,  F24F11/30 ,  G06K7/14 ,  G06Q10/087 ,  G06Q10/10

CPC classification number: G01N35/0099 ,  B01L3/50853 ,  B01L9/523 ,  G16H40/67 ,  G16H10/40 ,  G16H40/40 ,  F24F11/30 ,  G06K7/1413 ,  G06Q10/087 ,  G06Q10/10 ,  B01L2200/143 ,  B01L2300/021 ,  G01N2035/00356 ,  G05B2219/40269 ,  H04B1/3827

Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.

公开(公告)号：US20230266269A1

公开(公告)日：2023-08-24

申请号：US18172941

申请日：2023-02-22

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Manish KOCHAR

IPC: G01N27/416 ,  G01N21/76 ,  G01N21/64 ,  G01N21/66

CPC classification number: G01N27/416 ,  G01N21/6428 ,  G01N21/66 ,  G01N21/76

Abstract: An apparatus for conducting an assay based on an electrochemical process is provided. The apparatus includes a first detector configured to capture data associated with the electrochemical process; a second detector configured to capture data associated with the electrochemical process; and a beam splitting device configured to split emitted light from the electrochemical process into a first light beam directed at the first detector and a second light beam directed at the second detector.

公开(公告)号：US20230061508A1

公开(公告)日：2023-03-02

申请号：US17887191

申请日：2022-08-12

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Scott DOWDELL ,  Nicholas CARBONE ,  Charles CLINTON ,  Mark BILLADEAU ,  Manish KOCHAR ,  Nicholas FOX-LYON ,  Alexander TUCKER-SCHWARTZ ,  George SIGAL ,  Gisbert SPIELES ,  Jules VANDERSARL ,  Jacob WOHLSTADTER ,  Aaron LEIMKUEHLER ,  Jeffrey PETTINGILL ,  Leo TABAKIN ,  Bandele JEFFREY-COKER

IPC: B01L3/00 ,  G01N27/49 ,  G01N27/403 ,  G01N27/327

Abstract: Electrochemical cells and methods for their production are provided. In particular, multi-well assay plates including multi-electrode wells are provided. The multi-electrode wells contain multiple electrodes that are electrically isolated from one another, permitting the various electrodes of the various wells to be addressed in any suitable combination.

公开(公告)号：US20220244188A1

公开(公告)日：2022-08-04

申请号：US17603771

申请日：2020-04-22

Applicant: Gary I. KRIVOY ,  Cecilia ZIMMERMAN ,  Jules VANDERDARL ,  Sandor KOVACS ,  Aaron LEIMKUEHLER ,  Leo TABAKIN ,  Jon WILLOUGHBY ,  Manish KOCHAR ,  Charles M. CLINTON ,  Meso Scale Technologies, LLC.

Inventor： Gary I. KRIVOY ,  Cecilia ZIMMERMAN ,  Jules VANDERSARL ,  Sandor KOVACS ,  Aaron LEIMKUEHLER ,  Leo TABAKIN ,  Jon WILLOUGHBY ,  Manish KOCHAR ,  Charles M. CLINTON

IPC: G01N21/76 ,  G01N35/02 ,  G01N35/00

Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation ar described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format. Also disclosed are systems, devices, and methods provided herein for using a CCD camera based system to generate measurements having reduced crosstalk between measurements of multiple spatially separated subjects. CCD camera based systems as provided herein use improved reference level clamping circuits configured to fully reset reference levels during CCD readout, thereby reducing a level of crosstalk between measurements.

公开(公告)号：US20210356482A1

公开(公告)日：2021-11-18

申请号：US17321099

申请日：2021-05-14

Applicant: Meso Scale Technologies, LLC.

Inventor： Dimitri Mikael MOFFITT ,  Aaron LEIMKUEHLER ,  Victor PELLICIER ,  Todd SMITH ,  Gary KRIVOY ,  Eric JONES ,  Jennifer PARKER ,  Slavi MIRTCHEV ,  Nicholas SAMMONS ,  Manish KOCHAR ,  Jacob N. WOHLSTADTER

IPC: G01N35/00 ,  B01L3/00

Abstract: The present disclosure relates to an automated assay system adapted to receive consumables in the conduct of an assay. The assay system includes at least one of a loading cart, a door support system, a waste storage unit, and a robotic subsystem. The loading cart is configured to organize and transport consumables necessary for the performance of the assay system. The door support system is configured to maintain stability of doors of the automated assay system. The waste storage unit is configured to provide convenient disposal of consumables associated with the automated assay system. The robotic subsystem is configured to transport consumables within the automated assay system.