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公开(公告)号:US20240053364A1
公开(公告)日:2024-02-15
申请号:US18126546
申请日:2023-03-27
Applicant: Meso Scale Technologies, LLC.
Inventor: Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko
IPC: G01N33/68
CPC classification number: G01N33/6893 , G01N2800/347 , G01N2800/52 , G01N2333/70578 , G01N2333/4706 , G01N2333/4727 , G01N2333/70596 , G01N2333/8146
Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号:US20220215905A1
公开(公告)日:2022-07-07
申请号:US17701879
申请日:2022-03-23
Applicant: Meso Scale Technologies, LLC.
Inventor: Charles M. Clinton , Xinri Cong , Eli N. Glezer , Sudeep Kumar , Carl Stevens , Michael Vock , Jon S. Willoughby
IPC: G16C20/20 , G01N35/00 , G01N33/543 , B01L3/00 , G16H10/40
Abstract: The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
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公开(公告)号:US10814327B2
公开(公告)日:2020-10-27
申请号:US15646578
申请日:2017-07-11
Applicant: Meso Scale Technologies, LLC.
Inventor: Eli N. Glezer , Stephen Higgins , Sandor Kovacs , Sudeep Kumar , Kenneth Page , Kristian Roth , George Sigal
Abstract: Assay cartridges are described that have purification, reaction, and detection zones and other fluidic components which can include sample chambers, waste chambers, conduits, vents, reagent chambers, reconstitution chambers and the like. The assay cartridges are used to conduct multiplexed nucleic acid measurements. Also described are kits including such cartridges, methods of using the same, and a reader configured to analyze an assay conducted using an assay cartridge.
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公开(公告)号:US20190291103A1
公开(公告)日:2019-09-26
申请号:US16227081
申请日:2018-12-20
Applicant: Meso Scale Technologies, LLC.
Inventor: Eli N. Glezer , Sudeep Kumar , Pankaj Oberoi , George Sigal , Michael Tsionsky
IPC: B01L3/00 , C12Q1/6804 , G01N33/68 , G01N33/543 , C12Q1/6816 , C12Q1/6876
Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
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公开(公告)号:US20190083976A1
公开(公告)日:2019-03-21
申请号:US16210165
申请日:2018-12-05
Applicant: Meso Scale Technologies, LLC
Inventor: Eli N. Glezer , Sudeep Kumar , Pankaj Oberoi , George Sigal , Michael Tsionsky
IPC: B01L3/00 , C12Q1/6804 , G01N33/68 , G01N33/543 , C12Q1/6876 , C12Q1/6816
Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
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公开(公告)号:US20240361322A1
公开(公告)日:2024-10-31
申请号:US18538543
申请日:2023-12-13
Applicant: Meso Scale Technologies, LLC.
Inventor: Anahit Aghvanyan , Eli N. Glezer , John Kenten , Sudeep Kumar , Galina Nikolenko , Martin Stengelin
IPC: G01N33/574 , A61K39/395
CPC classification number: G01N33/57423 , A61K39/39533
Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
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公开(公告)号:US11600373B2
公开(公告)日:2023-03-07
申请号:US16555271
申请日:2019-08-29
Applicant: MESO SCALE TECHNOLOGIES, LLC , THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
Inventor: William F. Blakely , Eli N. Glezer , John Kenten , Sudeep Kumar , Anu Mathew , Natalia I. Ossetrova , George Sigal
IPC: G01N33/566 , G01N33/569 , G01N33/68 , G16H20/40 , G01T1/02 , G01T1/00 , G01N27/327 , G01N35/00
Abstract: The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
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公开(公告)号:US20220252590A1
公开(公告)日:2022-08-11
申请号:US17553441
申请日:2021-12-16
Applicant: Meso Scale Technologies, LLC.
Inventor: Sudeep Kumar , George Sigal , Michael Tsionsky
IPC: G01N33/543 , G01N33/53 , C12Q1/6823 , C12Q1/6832 , C12Q1/6834
Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
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公开(公告)号:US11315662B2
公开(公告)日:2022-04-26
申请号:US16594301
申请日:2019-10-07
Applicant: Meso Scale Technologies, LLC.
Inventor: Charles M. Clinton , Xinri Cong , Eli N. Glezer , Sudeep Kumar , Carl Stevens , Michael Vock , Jon S. Willoughby
Abstract: The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
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公开(公告)号:US20210402390A1
公开(公告)日:2021-12-30
申请号:US17476880
申请日:2021-09-16
Applicant: Meso Scale Technologies, LLC.
Inventor: Eli N. Glezer , Sudeep Kumar , Pankaj Oberoi , George Sigal , Michael Tsionsky
IPC: B01L3/00 , C12Q1/6876 , G01N33/543 , C12Q1/6816 , C12Q1/6804 , G01N33/68
Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.
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