公开(公告)号：US11214844B2

公开(公告)日：2022-01-04

申请号：US16189692

申请日：2018-11-13

Applicant: MODERN MEADOW, INC.

Inventor： Brendan Patrick Purcell ,  Suzanne Lee ,  Lixin Dai ,  Katherine Amy Congdon ,  Stephen M. Spinella ,  Chi Man Ng

IPC: C14B7/04 ,  C14C7/00 ,  C14C13/00 ,  C08H1/06 ,  C08L89/06 ,  D06N3/00 ,  D06N3/12

Abstract: The invention herein provides biofabricated materials having zonal properties and methods of making biofabricated materials having zonal properties.

公开(公告)号：US10370504B2

公开(公告)日：2019-08-06

申请号：US15433650

申请日：2017-02-15

Applicant: MODERN MEADOW, INC.

Inventor： Brendan Patrick Purcell ,  David Thomas Williamson ,  Francoise Suzanne Marga ,  Susan J. Schofer ,  Darryl Miles Cassingham ,  Stephen M. Spinella ,  Amy Congdon

IPC: C08J3/24 ,  C14C13/00 ,  D04H13/00 ,  D06P3/32 ,  C07K14/78 ,  C14C9/00 ,  C14C9/02 ,  D04H1/4382 ,  D01C3/00 ,  D06N3/00 ,  D04H1/00 ,  D06M15/05 ,  D01F4/00 ,  B32B5/26 ,  D06M15/15 ,  D06N7/00 ,  B32B5/02 ,  B32B7/12 ,  B32B9/02 ,  B32B15/02 ,  B32B15/14 ,  B32B23/10 ,  B32B27/12 ,  B32B29/02 ,  B32B1/08 ,  B32B3/26 ,  D06M101/06 ,  D06M23/16

Abstract: Described herein is a method for producing a biofabricated material from collagen or collagen-like proteins which are recombinantly produced and which contain substantially no 3-hydroxyproline. The collagen or collagen-like proteins are isolated from animal sources, or produced by recombinant DNA techniques or by chemical synthesis. The collagen or collagen-like proteins are fibrillated, crosslinked, dehydrated and lubricated thus forming the biofabricated material having a substantially uniform network of collagen fibrils.