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11.发明申请Apparatus and methods for treating stroke and controlling cerebral flow characteristics 审中-公开用于治疗中风和控制脑流动特征的装置和方法公开(公告)号：US20050267323A1
公开(公告)日：2005-12-01
申请号：US11146636
申请日：2005-06-06
CPC分类号： A61B17/3207 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12136 , A61B17/12172 , A61B17/22 , A61B17/221 , A61B2017/22034 , A61B2017/3435 , A61M25/1002 , A61M2025/09008 , A61M2025/09083 , A61M2025/09166 , A61M2025/1052
摘要： Apparatus and methods for treatment of stroke are provided. In a preferred embodiment, the present invention disposes at least one catheter having a distal occlusive member in either the common carotid artery (CCA) or both the vertebral artery (VA) and the CCA on the hemisphere of the cerebral occlusion. Blood flow in the opposing carotid and/or vertebral arteries may be inhibited. Retrograde or antegrade flow may be provided through either catheter independently to effectively control cerebral flow characteristics. Under such controlled flow conditions, a thrombectomy device may be used to treat the occlusion, and any emboli generated are directed into the catheter(s).
摘要翻译： 提供了用于治疗中风的装置和方法。 在优选实施例中，本发明将至少一个具有远端闭塞构件的导管配置在颈总动脉（CCA）或椎动脉（VA）和脑闭塞半球上的CCA两者中。 可以抑制相对的颈动脉和/或椎动脉中的血液流动。 可以独立地通过任一导管提供逆行或顺行流动以有效地控制脑流动特征。 在这种受控的流动条件下，可以使用血栓切除装置来治疗闭塞，并且所产生的任何栓塞被引导到导管中。
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12.发明申请Coiled sheet graft for single and bifurcated lumens and methods of making and use 失效单片和分叉腔的卷片移植物及其制作和使用方法公开(公告)号：US20050004654A1
公开(公告)日：2005-01-06
申请号：US10903804
申请日：2004-07-29
CPC分类号： A61F2/92 , A61F2/07 , A61F2/93 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2220/0008 , A61F2220/0016 , A61F2220/0041 , A61F2220/005 , A61F2220/0075
摘要： A prosthesis is provided for treating aneurysms, occlusive disease of vessels and body organs, and arterio-venous fistulas, occurring in single and bifurcated lumens. The prosthesis comprises an expandable coiled sheet portion having a biocompatible graft, either a sheet or tube, affixed thereto along part or all of the circumference of the coiled sheet portion. The prosthesis has a small delivery profile, making it suitable for use in a variety of body vessels. Methods of making and deploying the prosthesis in single and bifurcated lumens are also provided.
摘要翻译： 提供了一种假体，用于治疗动脉瘤，血管和身体器官的闭塞性疾病以及发生在单个和分叉腔内的动静脉瘘。 假体包括具有生物相容性移植物（片或管）的可膨胀卷曲片部分，其沿着盘绕片部分的圆周的部分或全部固定到其上。 假体具有小的输送轮廓，使其适用于各种身体血管。 还提供了在单个和分叉腔内制造和部署假体的方法。
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公开(公告)号：US06458152B1
公开(公告)日：2002-10-01
申请号：US09547247
申请日：2000-04-11
IPC分类号： A61F206
CPC分类号： A61F2/92 , A61F2/07 , A61F2/93 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2220/0008 , A61F2220/0016 , A61F2220/0041 , A61F2220/005 , A61F2220/0075
摘要： A prosthesis is provided for treating aneurysms, occlusive disease of vessels and body organs, and arterio-venous fistulas, occurring in single and bifurcated lumens. The prosthesis comprises an expandable coiled sheet portion having a biocompatible graft, either a sheet or tube, affixed thereto along part or all of the circumference of the coiled sheet portion. The prosthesis has a small delivery profile, making it suitable for use in a variety of body vessels. Methods of making and deploying the prosthesis in single and bifurcated lumens are also provided.
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公开(公告)号：US06425915B1
公开(公告)日：2002-07-30
申请号：US09047891
申请日：1998-03-25
IPC分类号： A61F206
CPC分类号： A61F2/88 , A61F2/91 , A61F2/92 , A61F2220/0016
摘要： A stent including a helical mesh coil is provided having a substantially rectangular cross-section and a band width equal to at least one-quarter to one-third of the maximum expanded circumference of the stent. The helical mesh has a multiplicity of openings forming a lattice that preferably provides about 60% open space or more. Alternative embodiments of the stent include free ends that preferentially overlap neighboring turns of the coil, and integrally formed barbs that enhance resistance to localized compressive forces. Methods of deploying the helical mesh coil stent also provided.
摘要翻译： 提供了包括螺旋状网状线圈的支架，其具有基本上矩形的横截面和等于支架的最大扩张周长的至少四分之一至三分之一的带宽。 螺旋网具有形成格子的多个开口，其优选地提供约60％的开放空间或更多。 支架的替代实施例包括优先重叠线圈的相邻匝的自由端和增强对局部压缩力的抵抗力的整体形成的倒刺。 还提供了展开螺旋网状线圈支架的方法。
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公开(公告)号：US5785679A
公开(公告)日：1998-07-28
申请号：US504293
申请日：1995-07-19
CPC分类号： A61F2/07 , A61F2/89 , A61F2/90 , A61F2002/077 , A61F2250/0003
摘要： Methods and apparatus are provided for temporarily excluding an aneurysm or an arterio-venous fistula from a flow path by transluminally disposing a hollow balloon catheter structure within the aneurysm so that its proximal and distal ends extend past the aneurysm while maintaining continuity of the flow path, and then injecting a synthetic molding material or a biological hardening agent into the aneurysm cavity to cause solidification of the volume within the cavity. Once the material within the excluded aneurysm has solidified, the balloon catheter structure is deflated and removed, so that the hardened mass forms a new lining for the organ or vessel, and relieves the weakened tissue of the aneurysm or fistula from further flow-induced stress.
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16.发明授权Apparatus and method for dilating a lumen and for inserting an intraluminal graft 失效用于扩张内腔和插入腔内移植物的装置和方法
公开(公告)号：US5713907A
公开(公告)日：1998-02-03
申请号：US504820
申请日：1995-07-20
申请人： Michael Hogendijk , Mark H. Wholey
发明人： Michael Hogendijk , Mark H. Wholey
CPC分类号： A61F2/95 , A61M29/02 , A61F2002/9505 , A61F2002/9517 , A61F2250/0097
摘要： An insertion device for an intraluminal graft is provided, including a deployment catheter which has a deployment shaft and an expanding frame with an umbrella-like assembly. The assembly is suitable for radially expanding a graft. The device also includes a deployment grip connected to the deployment shaft. A coil interposed between the deployment grip and the expanding frame resiliently urges the expanding frame, with the deployment grip reversibly operating the expanding frame thereby. The deployment catheter collapses for removal from the vessel lumen after the intraluminal graft has been introduced therein. This intraluminal graft is deployed through a catheter and expanded in place to anchor the graft to the vessel wall. The expanding frame is then collapsed and withdrawn from the lumen. The insertion device also can be configured as an intraluminal dilation device that can be used to dilate a lumen and to ensnare an intraluminal object.
摘要翻译： 提供了一种用于腔内移植物的插入装置，包括具有展开轴的展开导管和具有伞形组件的扩张框架。 该组件适于径向扩张移植物。 该装置还包括连接到展开轴的展开夹具。 插入展开夹具和扩展框架之间的线圈弹性地促使扩展框架，其中展开夹具可逆地操作膨胀框架。 在腔内移植物被引入之后，展开导管塌陷以从血管腔排出。 该管腔内移植物通过导管部署并扩张就位以将移植物锚定到血管壁。 然后将膨胀的框架从管腔收缩并从腔中取出。 插入装置还可以被配置为腔内扩张装置，其可以用于扩张内腔并锁定管腔内物体。
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公开(公告)号：US07846198B2
公开(公告)日：2010-12-07
申请号：US10342427
申请日：2003-01-13
申请人： Michael Hogendijk
发明人： Michael Hogendijk
CPC分类号： A61F2/88 , A61F2/91 , A61F2/95 , A61F2/966 , A61F2002/828 , A61F2220/0041 , A61F2220/0058 , A61F2230/0054 , A61F2250/0068
摘要： The present invention is directed to an implantable vascular prosthesis configured for use in a wide range of applications, such as treating aneurysms, maintaining patency in a vessel, and allowing for the controlled delivery of therapeutic agents to a vessel wall. The prosthesis comprises a helical proximal section coupled to a distal anchoring section having a generally zig-zag configuration. The prosthesis is configured to comply to a vessel wall without substantially remodeling the vessel, and further is configured to be precisely deployed in a vessel without shifting during deployment. The prosthesis also has a substantially small delivery profile compared to other known stents, while having an increased surface area to enhance delivery of therapeutic agents.
摘要翻译： 本发明涉及一种可植入血管假体，其被配置用于广泛的应用中，例如治疗动脉瘤，维持血管中的开放性，并允许将治疗剂控制递送到血管壁。 假体包括联接到具有大致Z字形配置的远侧锚固部分的螺旋近端部分。 假体构造成符合血管壁而不会使血管基本上重塑，并且进一步构造成在展开期间精确地展开在容器中而不发生变化。 与其他已知的支架相比，假体也具有相当小的输送轮廓，同时具有增加的表面积以增强治疗剂的递送。
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公开(公告)号：US07699866B2
公开(公告)日：2010-04-20
申请号：US11106969
申请日：2005-04-15
IPC分类号： A61F2/01
CPC分类号： A61M25/104 , A61F2/01 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61M2025/09183
摘要： An emboli filtration apparatus is provided comprising a guide wire having a filter element captured thereon, so that the guide wire is free to rotate and translate while the filter element remains stationary. The apparatus allows for movement and rotation of the guide wire as devices are advanced over it to treat occlusive disease, substantially without dislodging the filter element. In a preferred embodiment, the guide wire comprises a proximal stop configured to reposition the filter element during a medical procedure without having to remove or insert additional interventional devices.
摘要翻译： 提供一种栓塞过滤装置，其包括具有捕获在其上的过滤元件的导丝，使得导丝在过滤元件保持静止时自由旋转和平移。 该设备允许导线的移动和旋转，因为装置在其上前进以治疗闭塞性疾病，基本上不会移除过滤元件。 在优选实施例中，导丝线包括近端止动件，其构造成在医疗过程期间重新定位过滤器元件，而不必移除或插入额外的介入装置。
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19.发明申请PERCUTANEOUS DELIVERY AND RETRIEVAL SYSTEMS FOR SHAPE-CHANGING ORTHOPEDIC JOINT DEVICES 审中-公开用于形状改变对称连接器件的PERCUTANEOUS递送和检索系统公开(公告)号：US20080255501A1
公开(公告)日：2008-10-16
申请号：US12099296
申请日：2008-04-08
CPC分类号： A61F2/30721 , A61B17/562 , A61B17/8872 , A61B2017/00004 , A61B2017/00867 , A61B2017/2925 , A61F2/38 , A61F2002/30092 , A61F2002/30113 , A61F2002/30115 , A61F2002/30125 , A61F2002/30131 , A61F2002/30136 , A61F2002/30143 , A61F2002/30149 , A61F2002/30153 , A61F2002/30156 , A61F2002/30158 , A61F2002/30177 , A61F2002/30179 , A61F2002/30291 , A61F2002/30754 , A61F2002/4415 , A61F2210/0014 , A61F2230/0004 , A61F2230/0006 , A61F2230/0008 , A61F2230/0013 , A61F2230/0017 , A61F2230/0019 , A61F2230/0023 , A61F2230/0026 , A61F2230/0056 , A61F2230/0058 , A61F2230/0091
摘要： Delivery and retrieval systems for delivering or retrieving a shape-changing percutaneously implantable orthopedic device joint prosthesis that can move between a generally arcuate configuration and a substantially straightened or slightly curved configuration. The orthopedic device can be delivered with a needle that is joint expanding, actuating, pivotable, or can include a balloon. The orthopedic device acts as a soft compliant bearing surface or cushion that minimizes the bone-on-bone wear from articulation and loading and may include a covering or coating with tissue or an expanding hydrophilic material. The orthopedic device delivery system can include a loading device with a channel for storing the orthopedic device in a non-straightened configuration and orienting the orthopedic device in the proper implantation orientation. The orthopedic device can be advanced or retrieved through the loading device with a knob and/or a flexible plunger.
摘要翻译： 用于递送或取回形状改变的经皮植入式整形外科装置关节假体的输送和检索系统，其能够在大致弓形构型和基本上直线化或略微弯曲的构型之间移动。 整形外科装置可以用接头膨胀，致动，可枢转或可以包括气囊的针进行输送。 整形外科装置充当软柔软的支承表面或垫子，其使得关节和负荷时的骨骼上的磨损最小化，并且可以包括具有组织或膨胀的亲水材料的覆盖物或涂层。 整形外科装置输送系统可以包括具有通道的加载装置，该通道用于将整形外科装置存储在非矫直构造中，并使整形外科装置以适当的植入方向取向。 整形外科装置可以通过带有旋钮和/或柔性柱塞的加载装置进行提升或回收。
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公开(公告)号：US07223253B2
公开(公告)日：2007-05-29
申请号：US10209207
申请日：2002-07-29
申请人： Michael Hogendijk
发明人： Michael Hogendijk
CPC分类号： A61M1/3621 , A61B17/22 , A61M1/0066 , A61M1/0068 , A61M25/00 , A61M2025/1052 , A61M2202/0413 , A61M2202/06 , A61M2205/7545
摘要： The present invention is directed to a blood aspiration system that is configured to enable various types of aspiration through a working lumen of a catheter. The blood aspiration system facilitates natural aspiration by providing a circuit between a patient's arterial and venous vasculature, and also comprises a manually actuated pump configured to selectively vary rates of aspiration in the working lumen. The blood aspiration system further comprises an external port that allows suction-assisted aspiration or infusion through the working lumen, and further comprises a detachable filter that removes emboli prior to reperfusing blood into a patient's venous vasculature.
摘要翻译： 本发明涉及一种血液抽吸系统，其被配置为能够通过导管的工作腔进行各种类型的抽吸。 血液抽吸系统通过在患者的动脉和静脉血管系统之间提供电路来促进自然抽吸，并且还包括被配置为选择性地改变工作腔内的抽吸速率的手动致动泵。 血液吸入系统还包括外部端口，其允许抽吸辅助抽吸或输注通过工作腔，并且还包括可拆卸过滤器，其在将血液再次灌注到患者的静脉血管中之前去除栓塞。
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