公开(公告)号：US4669756A

公开(公告)日：1987-06-02

申请号：US735528

申请日：1985-05-20

Applicant: Michael M. Cassaday ,  Leon Castellani ,  Stephen Saros

Inventor： Michael M. Cassaday ,  Leon Castellani ,  Stephen Saros

IPC: G01N30/38 ,  B01D15/08 ,  F16B7/18 ,  F16L19/00 ,  F16L47/00 ,  G01N30/26 ,  F16L27/12

CPC classification number: F16L47/00

Abstract: New and improved connector is provided for the zero dead volume connection of separate, like diameter flexible tubing lengths by direct tubing length end abutment and connection under controlled conditions. The connector is particularly adapted for use with tubing lengths of fluorocarbon or like materials in contemporary biomedical sample liquid analysis systems which utilize an immiscible isolation liquid or "oil" to minimize sample liquid carryover and maximize the accuracy of sample liquid analysis results.

Abstract translation: 提供了新的和改进的连接器，用于在受控条件下通过直接管道长度端邻接和连接的单独的类似直径的柔性管段的零死体积连接。 连接器特别适用于当代生物医学样品液体分析系统中的氟化碳或类似材料的管道长度，其利用不混溶的隔离液体或“油”以最小化样品液体携带并最大化样品液体分析结果的准确性。

公开(公告)号：US4602995A

公开(公告)日：1986-07-29

申请号：US735847

申请日：1985-05-20

Applicant: Michael M. Cassaday ,  Rand Herron ,  Kenneth F. Uffenheimer ,  John L. Smith

Inventor： Michael M. Cassaday ,  Rand Herron ,  Kenneth F. Uffenheimer ,  John L. Smith

IPC: G01N33/48 ,  G01N1/00 ,  G01N33/49 ,  G01N35/10 ,  B01D33/00

CPC classification number: G01N33/491

Abstract: New and improved, liquid level adjusting and filtering device is provided, and is operable upon insertion into a container to automatically adjust the level of a liquid as contained in the container to a predetermined, precisely repeatable location, and to filter the thusly level-adjusted liquid. The device is particularly adapted for use in conjunction with test tube-like devices, in the nature of those marketed under the Trademark "Vacutainer" by the Becton-Dickinson Company of East Rutherford, NJ, containing whole blood samples which have been separated as by centrifugation into respective blood cell, buffy and blood serum layers; and is operable in that context to present blood serum samples to automated sample analysis systems at the same predetermined and precisely repeatable location relative to the aspirating probe means of such systems.

Abstract translation: 提供了新的和改进的液位调节和过滤装置，并且在插入到容器中以便将包含在容器中的液体的水平自动调节到预定的，精确可重复的位置时可操作，并且将因此被调节的水平 液体。 该装置特别适合与试管类装置一起使用，其性质是由新泽西州东卢瑟福的Becton-Dickinson公司在“Vacutainer”商标范围内销售的，其中包含已经被分离的全血样本 离心分离到各自的血细胞，血沉棕质和血清层; 并且在该上下文中可操作地将相对于这种系统的抽吸探针装置的血清样品呈现在相同的预定和精确可重复的位置处的自动化样品分析系统。

公开(公告)号：US4422773A

公开(公告)日：1983-12-27

申请号：US175222

申请日：1980-08-04

Applicant: Michael M. Cassaday ,  John L. Smith

Inventor： Michael M. Cassaday ,  John L. Smith

IPC: B01F5/00 ,  B01F5/06 ,  G01N35/08

CPC classification number: B01F5/0646 ,  B01F5/0647 ,  G01N35/08

Abstract: New and improved apparatus and method for thorough, non-invasive mixing of a flowing fluid stream, either continuous or segmented, are provided and, as disclosed, are embodied in a mixing conduit which comprises a plurality of interconnected bends, which may be in the form of arcuate coils or sections, successive arcuate sections being operable to establish secondary flow patterns in differing orientations within the flowing fluid stream, or individual segments thereof. Such arcuate sections may be disposed in a same plane, if formed in serpentine fashion, or in non-parallel, preferably orthogonal planes, if formed in a tortuous fashion. Also, the arcuate sections, or a series thereof may be formed in stacked fashion and located in essentially parallel planes.

Abstract translation: 提供了用于彻底，非侵入式混合连续或分段的流体流的新的和改进的装置和方法，并且如所公开的那样，它们被实施在混合管道中，混合管道包括多个互连的弯头，其可以在 弧形线圈或部分的形式，连续的弓形部分可操作以在流动流体流或其各个部分内以不同取向建立二次流动模式。 如果以蛇形方式形成，或者如果以曲折方式形成，则这些弧形部分可以设置在相同的平面中，或者在非平行的，优选正交的平面中。 此外，弓形部分或其一系列可以以堆叠方式形成并且位于基本上平行的平面中。