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公开(公告)号：US20160369251A1
公开(公告)日：2016-12-22
申请号：US15137852
申请日：2016-04-25
Applicant: NOVOZYMES A/S , NOVOZYMES NORTH AMERICA, INC.
Inventor： Carsten Andersen , Randall Deinhammer , Thomas Agersten Poulsen , Miguel Duarte Toscano , Peter Kamp Hansen , Henrik Friis-Madsen , Anders Viksoe-Nielsen , Signe Eskildsen Larsen , Lars L.H. Christensen
CPC classification number: C12N9/2417 , C11D3/386 , C11D3/38681 , C12N9/2414 , C12N15/8257 , C12P7/06 , C12P7/14 , C12P19/02 , C12P19/04 , C12P19/14 , C12P2203/00 , C12Y302/01001 , Y02E50/17
Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes.
Abstract translation: 本发明涉及母体α-淀粉酶的变体。 本发明还涉及编码变体的多核苷酸和包含多核苷酸的核酸构建体，载体和宿主细胞，以及使用变体酶的方法。
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公开(公告)号：US12037614B2
公开(公告)日：2024-07-16
申请号：US17717176
申请日：2022-04-11
Applicant: Novozymes A/S
Inventor： Miguel Duarte Guilherme Pereira Toscano , Thomas Agersten Poulsen , Carsten Horslev Hansen , Lone Baunsgaard , Keith Gibson
CPC classification number: C12N9/20 , C11D3/38627 , C11D3/38672
Abstract: The present invention relates to variants of a parent lipase which has lipase activity and comprise one or more substitutions corresponding to G23S, D27N, A40I, F51I,L, E56R, D57N, V60E,K, K98I, N101D, R118F, G163S, T231R, N233R, Y220F, T244E, and P256T using SEQ ID NO: 2 for numbering. The present invention also relates to compositions or microcapsule compositions comprising a lipase variant of the invention and to liquid products comprising a microcapsule composition of the invention as well as the use of the microcapsule composition for stabilizing lipase variants of the invention.
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公开(公告)号：US20230313165A1
公开(公告)日：2023-10-05
申请号：US18042282
申请日：2021-08-24
Applicant: Novozymes A/S
Inventor： Thomas Agersten Poulsen , Aishwarya Deshpande , Rajendra Kulothungan Sainathan , Bjoern Lennart Pierre Alexa Cassland , Balasubramanian Venkatakrishnan , Jinal Kaushikkumar Shukla , Simanti Bhattacharya , Sidharth Ramanand , Subith Krishna
CPC classification number: C12N9/2434 , C11D3/38636 , C11D11/0017 , C11D11/0023
Abstract: The present disclosure relates to xyloglucanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
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公开(公告)号：US10550373B2
公开(公告)日：2020-02-04
申请号：US15137852
申请日：2016-04-25
Applicant: NOVOZYMES A/S , NOVOZYMES NORTH AMERICA, INC.
Inventor： Carsten Andersen , Randall Deinhammer , Thomas Agersten Poulsen , Miguel Duarte Toscano , Peter Kamp Hansen , Henrik Friis-Madsen , Anders Viksoe-Nielsen , Signe Eskildsen Larsen , Lars L. H. Christensen
IPC: C12N9/28 , C11D3/386 , C12P7/06 , C12P19/04 , C12P19/14 , C12N9/26 , C12P7/14 , C12P19/02 , C12N15/82
Abstract: The present invention relates to variants of a parent alpha-amylase. The present invention also relates to polynucleotides encoding the variants and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes.
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公开(公告)号：US20190284541A1
公开(公告)日：2019-09-19
申请号：US16423866
申请日：2019-05-28
Applicant: NOVOZYMES A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
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Patent Agency Ranking
公开(公告)号：US10351833B2
公开(公告)日：2019-07-16
申请号：US14785412
申请日：2014-05-13
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning. The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
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公开(公告)号：US20160076012A1
公开(公告)日：2016-03-17
申请号：US14785412
申请日：2014-05-13
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Glystorff , Jesper Vind , Christian Jackel
CPC classification number: C12N9/18 , A61K8/66 , B65D65/46 , C11D3/38627 , C11D17/042 , C11D17/043 , C12N9/20 , C12Y301/01 , C12Y301/01003
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning. The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.
Abstract translation: 本发明涉及包含变体具有脂肪酶活性的母体脂肪酶的变体的洗涤剂组合物与SEQ ID NO：2具有至少60％但小于100％的序列同一性，并且包括在对应于T231R + N233R的位置和 SEQ ID NO：2的D96E，D111A，D254S，G163K，P256T，G91T和G38A的至少一个或多个（例如数个）。本发明还涉及组合物的用途， 清洁方法 本发明还涉及编码变体的变体和多核苷酸; 核酸构建体，载体和包含多核苷酸的宿主细胞。
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公开(公告)号：US20250084394A1
公开(公告)日：2025-03-13
申请号：US18896095
申请日：2024-09-25
Applicant: Novozymes A/S
Inventor： Svend Gunnar Kaasgaard , Frank Winther Rasmussen , Roland Alexander Pache , Lars Anderson , Mette Louise Dissing Overgaard , Thomas Agersten Poulsen , Lars Giger
Abstract: Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
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公开(公告)号：US20250002880A1
公开(公告)日：2025-01-02
申请号：US18826915
申请日：2024-09-06
Applicant: Novozymes A/S
Inventor： Marco Malten , Kim Borch , Lise Munch Mikkelsen , Thomas Agersten Poulsen , Luise Erlandsen , Hanne Philbert Nielsen , Carsten Horslev Hansen , Allan Svendsen , Christian Lundager Gylstorff , Jesper Vind , Christian Jackel
Abstract: The present invention relates to detergent compositions comprising a variant of a parent lipase which variant has lipase activity, has at least 60% but less than 100% sequence identity with SEQ ID NO: 2, and comprises substitutions at positions corresponding to T231R+N233R and at least one or more (e.g., several) of D96E, D111A, D254S, G163K, P256T, G91T, and G38A of SEQ ID NO: 2. The present invention also relates to use of the compositions, methods of producing the compositions, and methods of cleaning.
The present invention furthermore relates to variants and polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides.-
公开(公告)号：US12129498B2
公开(公告)日：2024-10-29
申请号：US18302506
申请日：2023-04-18
Applicant: Novozymes A/S
Inventor： Svend Gunnar Kaasgaard , Frank Winther Rasmussen , Roland Alexander Pache , Lars Anderson , Mette Louise Dissing Overgaard , Thomas Agersten Poulsen , Lars Giger
CPC classification number: C12N9/2437 , C11D3/38618 , C11D3/38645 , C12N9/50 , C12N15/80 , C12Y302/01004
Abstract: Disclosed are variants of a cellulase having improved stability in the presence of a protease, and the use of such variants in laundry.
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