公开(公告)号：US10687912B2

公开(公告)日：2020-06-23

申请号：US15882758

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B90/30 ,  A61B17/02 ,  A61F9/007 ,  A61B3/00 ,  G02B27/09 ,  G02B6/14 ,  A61B18/22

Abstract: Fiber-based mode mixing techniques may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibrating fiber mechanism may impart mechanical motion to a portion of the optical fiber to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US20180147087A1

公开(公告)日：2018-05-31

申请号：US15820824

申请日：2017-11-22

Applicant: Novartis AG

Inventor： Gerald David Bacher ,  Mark David Labelle

IPC: A61F9/008 ,  A61B3/00 ,  A61B90/00

CPC classification number: A61F9/008 ,  A61B3/0008 ,  A61B3/0016 ,  A61B3/12 ,  A61B3/13 ,  A61B90/04 ,  A61B2090/306 ,  A61F2009/00874 ,  A61F2009/00878 ,  G02B26/00

Abstract: The present disclosure provides a system and method for monitoring phototoxicity caused by vitreous visualization device (“VVD”) illumination during ophthalmic surgery. The systems and methods determine the cumulative amount of optical energy incident on the retina, which corresponds to phototoxicity, the distance between a cutter of the VVD and the retina, and areas where the vitreous has been removed, or any combination thereof. The disclosure further provides a method for monitoring and preventing phototoxicity caused by VVD illumination during ophthalmic surgery. The method may further include determining the distance between a cutter of the VVD and the retina, and determining areas where the vitreous has been removed based on focus areas of the retina that the plurality of light spots has contacted.

公开(公告)号：US20180140373A1

公开(公告)日：2018-05-24

申请号：US15793555

申请日：2017-10-25

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Andrew David Johnson ,  Ronald Smith ,  Gerald David Bacher ,  Alireza Mirsepassi ,  Ryan Takakawa

IPC: A61B90/30

Abstract: The present disclosure provides a vitreous visualization system including a vitreous illuminator including a vitreous visualization light source and a vitreous visualization tool that transmits lights from the vitreous visualization light source into an eye having vitreous, a pupil, and a vitreous-pupil axis. The vitreous visualization system further includes a general illuminator, which may include a general light source and a general illumination tool that transmits light from the general light source into the eye. The present disclosure further provided a vitreous visualization system including only a vitreous illuminator that transmits light from the vitreous visualization light source into an eye having vitreous, a pupil, a vitreous-pupil axis, and a retina at an angle B with the vitreous-pupil axis of the eye such that the brightness of vitreous in the eye is higher than the brightness of the retina of the eye.

公开(公告)号：US20180140179A1

公开(公告)日：2018-05-24

申请号：US15793656

申请日：2017-10-25

Applicant: Novartis AG

Inventor： Mark David LaBelle ,  Ryan Takakawa ,  Alireza Mirsepassi ,  Cesario Dos Santos ,  Gerald David Bacher ,  Eyad Ammari

IPC: A61B3/00 ,  A61F9/007 ,  F21V8/00

CPC classification number: A61B3/0008 ,  A61B90/30 ,  A61B2090/306 ,  A61F9/007 ,  G02B6/0008

Abstract: The present disclosure provides a vitreous visualization system including a general light source, a general conduit that transmits light from the general light source through a conduit portion of a general illumination optical fiber, and a combined vitreous visualization and general illumination tool that receives light from the general conduit. The combined vitreous visualization tool includes a vitreous visualization light source, a controller for the vitreous visualization light source, a vitreous visualization optical fiber, a tool portion of the general illumination optical fiber, and a probe tip through which at least parts of both the vitreous visualization optical fiber and the tool portion of the general illumination optical fiber pass.

公开(公告)号：US11065077B2

公开(公告)日：2021-07-20

申请号：US15882815

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B90/30 ,  A61F9/008 ,  A61B17/02 ,  G02B26/08 ,  A61B3/00 ,  G02B23/24 ,  F21V8/00

Abstract: Mechanical optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A mechanical optical element, such as a rotating prism or a mirror membrane, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US11006822B2

公开(公告)日：2021-05-18

申请号：US15882867

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B1/07 ,  A61B3/00 ,  A61B90/30 ,  G02B26/06 ,  G02B23/24 ,  G02B26/08

Abstract: Pixelated array optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A pixelated phase array, such as a digital micromirror device or an LCD phase plate, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US10537401B2

公开(公告)日：2020-01-21

申请号：US15793555

申请日：2017-10-25

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Andrew David Johnson ,  Ronald Smith ,  Gerald David Bacher ,  Alireza Mirsepassi ,  Ryan Takakawa

IPC: A61B1/06 ,  A61B90/30 ,  A61B90/20 ,  A61B90/00 ,  A61B3/00 ,  A61B3/13 ,  A61F9/007

Abstract: The present disclosure provides a vitreous visualization system including a vitreous illuminator including a vitreous visualization light source and a vitreous visualization tool that transmits lights from the vitreous visualization light source into an eye having vitreous, a pupil, and a vitreous-pupil axis. The vitreous visualization system further includes a general illuminator, which may include a general light source and a general illumination tool that transmits light from the general light source into the eye. The present disclosure further provided a vitreous visualization system including only a vitreous illuminator that transmits light from the vitreous visualization light source into an eye having vitreous, a pupil, a vitreous-pupil axis, and a retina at an angle B with the vitreous-pupil axis of the eye such that the brightness of vitreous in the eye is higher than the brightness of the retina of the eye.

公开(公告)号：US20180214238A1

公开(公告)日：2018-08-02

申请号：US15882790

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B90/30 ,  A61F9/007 ,  A61B17/02

Abstract: Focusing optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibration stage may impart mechanical motion to a condenser lens to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US20180214018A1

公开(公告)日：2018-08-02

申请号：US15882867

申请日：2018-01-29

Applicant: Novartis AG

Inventor： Cesario Dos Santos ,  Gerald David Bacher ,  Ronald Smith ,  Alireza Mirsepassi ,  Michael Papac

IPC: A61B3/00 ,  A61B1/07

CPC classification number: A61B3/0008 ,  A61B1/07 ,  A61B90/30 ,  A61B2090/306 ,  G02B23/2469 ,  G02B26/06 ,  G02B26/0833

Abstract: Pixelated array optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A pixelated phase array, such as a digital micromirror device or an LCD phase plate, may impart motion to an incident beam entering the optical fiber to generate a homogeneous illumination field from a coherent light source.

公开(公告)号：US20160166139A1

公开(公告)日：2016-06-16

申请号：US14571389

申请日：2014-12-16

Applicant: Novartis AG

Inventor： Gerald David Bacher ,  Ronald T. Smith

IPC: A61B3/00

CPC classification number: A61B3/0008 ,  A61B2090/306 ,  A61B2560/0276 ,  A61B2562/146 ,  A61B2562/228 ,  G02B6/0006 ,  G02B6/4214 ,  G02B6/4225 ,  G02B6/4286 ,  G02B6/4292

Abstract: An optical coupling efficiency detection assembly includes a first housing accommodating a beam splitter and a fiber port, a second housing accommodating a ferrule enclosing a monitoring fiber, and an attachment block attaching the first housing to the second housing to establish a parfocal arrangement among the beam splitter, the fiber port, and the ferrule. Further, an assembly method for the optical coupling efficiency detection assembly is disclosed. The assembly method may include providing a beam splitter and a fiber port in a first housing, providing a ferrule enclosing a monitoring fiber in a second housing, and attaching the second housing to the first housing via an attachment block to establish a parfocal arrangement among the beam splitter, the fiber port, and the ferrule.

Abstract translation: 光耦合效率检测组件包括容纳分束器和光纤端口的第一壳体，容纳封闭监控光纤的套圈的第二壳体和将第一壳体附接到第二壳体的附接块，以在射束之间建立对焦布置 分路器，光纤端口和套圈。 此外，公开了一种用于光耦合效率检测组件的组装方法。 组装方法可以包括在第一壳体中提供分束器和光纤端口，在第二壳体中提供封闭监控光纤的套圈，以及经由附接块将第二壳体附接到第一壳体，以在第一壳体之间建立对焦布置 分束器，光纤端口和套圈。