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公开(公告)号：US20200032239A1
公开(公告)日：2020-01-30
申请号：US16595999
申请日：2019-10-08
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Roberto Meidler , Oleg Belyaev , Liliana Bar , Israel Nur
Abstract: Provided are methods for lyophilization of an aqueous thrombin solution, thrombin solutions for use in such lyophilization methods, and solid thrombin compositions produced by such methods.
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12.发明申请公开(公告)号：US20180093010A1
公开(公告)日：2018-04-05
申请号：US15819773
申请日：2017-11-21
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Israel Nur , Roberto Meidler , Liliana Bar
CPC classification number: A61L24/106 , A61L24/043 , A61L24/108 , A61L31/046 , C08L89/00
Abstract: The invention relates to a proteolytic enzyme which is capable of forming fibrin when it reacts with fibrinogen, a fibrin-glue kit and a fibrin-glue formulation comprising an enzymatically-permissive concentration of a visualization agent and to their use in methods for prevention and/or reduction of adhesions and/or methods for promotion of blood coagulation sealing or filling body surfaces.
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公开(公告)号：US20160053299A1
公开(公告)日：2016-02-25
申请号：US14930799
申请日：2015-11-03
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor： Roberto Meidler , Anne J. Gorman , Israel Nur , Liliana Bar , Ashley DeAnglis
IPC: C12Q1/56
Abstract: A method is described for the measurement of thrombin activity in the presence of fibrinogen, or for the measurement of the functionality of fibrinogen in the presence of thrombin.
Abstract translation: 描述了在纤维蛋白原存在下测量凝血酶活性或在凝血酶存在下测量纤维蛋白原的功能的方法。
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公开(公告)号：US12203947B2
公开(公告)日：2025-01-21
申请号：US17318707
申请日：2021-05-12
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
Abstract: The present invention is directed to devices having a substance receiving portion and a membrane constituting the bottom of the substance receiving portion and having such a structure as to allow fluid disposed in the substance receiving portion to be transferred therefrom through the membrane when a vacuum force is applied to the bottom of the substance receiving portion for the purpose of an in-situ preparation of a sample to detect the presence and/or quantify of clottable fibrinogen. The present invention is also directed to corresponding methods, processes and systems.
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公开(公告)号：US20220098570A1
公开(公告)日：2022-03-31
申请号：US17546447
申请日：2021-12-09
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Roberto Meidler , Oleg Belyaev , Liliana Bar , Israel Nur
Abstract: Provided are methods for lyophilization of an aqueous thrombin solution, thrombin solutions for use in such lyophilization methods, and solid thrombin compositions produced by such methods.
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Patent Agency Ranking
公开(公告)号：US11225652B2
公开(公告)日：2022-01-18
申请号：US16595999
申请日：2019-10-08
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Roberto Meidler , Oleg Belyaev , Liliana Bar , Israel Nur
Abstract: Provided are methods for lyophilization of an aqueous thrombin solution, thrombin solutions for use in such lyophilization methods, and solid thrombin compositions produced by such methods.
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公开(公告)号：US20210263053A1
公开(公告)日：2021-08-26
申请号：US17318707
申请日：2021-05-12
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
Abstract: The present invention is directed to devices having a substance receiving portion; a membrane; and at least one blocking member configured for taking one position and another position to allow fluid communication when a vacuum force is applied to the bottom of the substance receiving portion for the purpose of an in-situ preparation of a sample to detect the presence of, and/or quantify, clottable fibrinogen. The present invention is also directed to corresponding methods, processes and systems.
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公开(公告)号：US20200033369A1
公开(公告)日：2020-01-30
申请号：US16566387
申请日：2019-09-10
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
Abstract: The present invention is directed to devices having a substance receiving portion; a membrane; and at least one blocking member configured for taking one position and another position to allow fluid communication when a vacuum force is applied to the bottom of the substance receiving portion for the purpose of an in-situ preparation of a sample to detect the presence of, and/or quantify, clottable fibrinogen. The present invention is also directed to corresponding methods, processes and systems.
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公开(公告)号：US09896716B2
公开(公告)日：2018-02-20
申请号：US14930799
申请日：2015-11-03
Applicant: Omrix Biopharmaceuticals Ltd. , Ethicon, Inc.
Inventor： Roberto Meidler , Anne J. Gorman , Israel Nur , Liliana Bar , Ashley DeAnglis
Abstract: A method is described for the measurement of thrombin activity in the presence of fibrinogen, or for the measurement of the functionality of fibrinogen in the presence of thrombin.
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公开(公告)号：US20170285047A1
公开(公告)日：2017-10-05
申请号：US15477692
申请日：2017-04-03
Applicant: Omrix Biopharmaceuticals Ltd.
Inventor： Elena Grimberg , Roberto Meidler , Yonit Tiberman , Nadav Orr , Nadav Ashkenazy
CPC classification number: G01N33/86 , B01D61/18 , B01D2325/38 , B01L3/502 , B01L2300/0681 , B01L2300/0829 , C12Q1/56
Abstract: Provided is a method, device and system for an in-situ preparation of a sample, for example, for use in detecting the presence of, and/or quantifying, clottable fibrinogen in such a sample.
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