公开(公告)号：US3914420A

公开(公告)日：1975-10-21

申请号：US42108973

申请日：1973-12-03

Applicant: ROUSSEL UCLAF

Inventor： GASC JEAN-CLAUDE ,  TORELLI VESPERTO

IPC: C07J1/00 ,  A61K20060101 ,  A61K31/56 ,  A61K31/565 ,  A61P13/02 ,  A61P15/00 ,  C07C20060101 ,  C07J17/00

CPC classification number: A61K31/565

Abstract: Novel steroids of the formula

WHEREIN R is alkyl of 1 to 3 carbon atoms and R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms and Alpha -tetrahydropyranyl with the proviso that R is not methyl where R1 is hydrogen having antiandrogenic properties and novel intermediates.

Abstract translation: 式WHEREIN R是具有1至3个碳原子的烷基的新型类固醇，R 1选自氢，1至4个碳原子的烷基和α-四氢吡喃基，条件是R不是甲基，其中R1是氢，具有 抗雄激素性质和新型中间体。

公开(公告)号：US3699100A

公开(公告)日：1972-10-17

申请号：US3699100D

申请日：1971-02-03

Applicant: ROUSSEL UCLAF

Inventor： NEDELEC LUCIEN ,  GASC JEAN-CLAUDE

IPC: A61K31/58 ,  C07J71/00 ,  C07C173/00

CPC classification number: C07J75/00

Abstract: NOVEL 11B,18-EPOXY-$4.9-ESTRADIENES OF THE FORMULA

3-(O=),11,18-(-O-),17-R,17-(R''-O-)ESTRA-4,9-DIENE

WHEREIN R IS SELECTED FROM THE GROUPS CONSISTING OF HYDROGEN AND ETHYNYL AND R'' IS SELECTED FROM THE GROUP CONSISTING OF HYDROGEN, ACYL OF AN ORGANIC CARBOXYLIC ACID OF 1 TO 18 CARBON ATOMS, LOWER ALIPHATIC, ARALYALIPHATIC AND HETEROCYCLIC WHICH HAVE ANIT-ANDROGENIC ACTIVITY, THEIR PREPARATION AND INTERMEDIATES THEREFROM.

公开(公告)号：US3629244A

公开(公告)日：1971-12-21

申请号：US3629244D

申请日：1969-08-13

Applicant: ROUSSEL UCLAF

Inventor： COSTEROUSSE GERMAIN ,  GASC JEAN-CLAUDE

IPC: A61K31/565 ,  A61K31/567 ,  A61K31/569 ,  C07J1/00 ,  C07J75/00 ,  C07C173/00

CPC classification number: A61K31/567 ,  A61K31/565 ,  A61K31/569 ,  C07J1/00 ,  C07J75/00

Abstract: WHEREIN A REPRESENTS A MEMBER SELECTED FROM THE GROUP CONSISTING OF OXYGEN, DI-LOWER-ALKOXY AND LOWER ALKYLENE DIOXY; R REPRESENTS ALKYL HAVING FROM 1 TO 4 CARBON ATOMS; R1 REPRESENTS A MEMBER SELECTED FROM THE GROUP CONSISTING OF HYDROGEN AND LOWER ALKYL; AND R2 REPRESENTS A MEMBER SELECTED FROM THE GROUP CONSISTING OF SUBSTITUTED AND UNSUBSTITUTED PHENYL, CYCLOHEXYL, CYCLOHEXENYL AND CYCLOHEXADIENYL. THESE COMPOUNDS HAVE A PARTICULARLY LONG-LASTING AND PERSISTENT ANABOLISANT AND ANDROGENIC ACTIVITY, ON SUBCUTANEOUS ADMINISTRATION.

3-(A=),7-R1,13-R,17-(R2-CH2-O-)GONA-4,9,11-TRIENE

THIS INVENTION RELATES TO 17B-ETHERS OF $4,9,11-GONATRIENES OF THE FORMULA

公开(公告)号：US3534139A

公开(公告)日：1970-10-13

申请号：US3534139D

申请日：1966-03-07

Applicant: ROUSSEL UCLAF

Inventor： BUCOURT ROBERT ,  GASC JEAN-CLAUDE

IPC: H03D9/04 ,  C07C169/08

CPC classification number: H03D9/04

公开(公告)号：US3453267A

公开(公告)日：1969-07-01

申请号：US3453267D

申请日：1965-12-28

Applicant: ROUSSEL UCLAF

Inventor： VIGNAU MICHEL ,  BUCOURT ROBERT ,  TESSIER JEAN ,  COSTEROUSSE GERMAIN ,  NEDELEC LUCIEN ,  GASC JEAN-CLAUDE ,  JOLY ROBERT ,  WARNANT JULIEN ,  GOFFINET BERNARD

IPC: C07J1/00 ,  C07J63/00 ,  C07J75/00 ,  C07C167/14 ,  C07C169/10 ,  C07C173/00

CPC classification number: C07J1/00 ,  C07J63/008 ,  C07J75/00