Novel haptene steroids
    1.
    发明授权
    Novel haptene steroids 失效
    新型辣椒素类固醇

    公开(公告)号:US3922292A

    公开(公告)日:1975-11-25

    申请号:US47988974

    申请日:1974-06-17

    Applicant: ROUSSEL UCLAF

    Abstract: Novel steroids of the formula

    WHEREIN X is selected from the group consisting of O and,

    Y is selected from the group consisting of hydrogen and -OH and when R1 is -(CH2)a-COOH in which a is equal to 2n + 3 and n is 0, 1 or 2, R2 is

    and when R1 is hydrogen, R2 is selected from the group consisting of AND N-Z-(CH2)c-COOH, b is a number from 3 to 18, c is a number from 1 to 8 and Z is selected from the group consisting of -Oand -NHCONH- which are haptenes or compounds capable of producing antibodies in vitro but are derived of antigenic properties and their preparation.

    Abstract translation: 式WHEREIN X的新型类固醇选自= O,OH ANGLE,HY选自氢和-OH,当R1是 - (CH2)a-COOH时,其中a等于 2n + 3,n为0,1或2,R2为H ANGLE H,当R1为氢时,R2选自AND = NZ-(CH2)c-COOH,b为3至18的数 ,c为1至8的数,Z选自-O-和-NHCONH-,其为半抗原或能在体外产生抗体但衍生自抗原性质及其制备的化合物。

    Novel antiandrogenic compounds
    2.
    发明授权
    Novel antiandrogenic compounds 失效
    新型抗雄激素化合物

    公开(公告)号:US3914420A

    公开(公告)日:1975-10-21

    申请号:US42108973

    申请日:1973-12-03

    Applicant: ROUSSEL UCLAF

    CPC classification number: A61K31/565

    Abstract: Novel steroids of the formula

    WHEREIN R is alkyl of 1 to 3 carbon atoms and R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms and Alpha -tetrahydropyranyl with the proviso that R is not methyl where R1 is hydrogen having antiandrogenic properties and novel intermediates.

    Abstract translation: 式WHEREIN R是具有1至3个碳原子的烷基的新型类固醇,R 1选自氢,1至4个碳原子的烷基和α-四氢吡喃基,条件是R不是甲基,其中R1是氢,具有 抗雄激素性质和新型中间体。

    Novel ' ' 9'- gonene-11-ones
    3.
    发明授权
    Novel ' ' 9'- gonene-11-ones 失效
    NOVEL''9'- GONENE-11-ONES

    公开(公告)号:US3876637A

    公开(公告)日:1975-04-08

    申请号:US43076974

    申请日:1974-01-04

    Applicant: ROUSSEL UCLAF

    Abstract: Wherein R is alkyl of 1 to 3 carbon atoms, R.sub.1 is selected from the group consisting of =0, ketals and
    R.sub.2 is selected from the group consisting of hydrogen and acyl of an organic carboxylic acid of 1 to 12 carbon atoms and X is selected from the group consisting of hydrogen and hydroxy which are valuable intermediates for the preparation of steroids such as adrenosterone.

    Racemates and optically active isomers of novel .DELTA..sup.9 gonene-11-ones of the formula

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