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公开(公告)号：US20150053211A1
公开(公告)日：2015-02-26
申请号：US13987732
申请日：2013-08-26
CPC分类号： A01N47/44 , A01N37/46 , A01N43/50 , A63B71/085 , A01N25/34
摘要： An aqueous oral spray designed to treat mouth guards against bacterial infection comprising: 1. A naturally derived di-basic amino acid derivative, 2. A natural sweetener which inhibits the adhesion of bacteria to the oral cavity and, 3. Optionally a natural flavor and/or natural dye 4. Optionally a mouth guard surface modified to absorb specific components of above oral aqueous solution so as to render mouth guard more effective overtime in inhibiting microorganism growth on surface and in contact with mouth surfaces compared with unmodified mouth guard surface.
摘要翻译： 一种设计用于治疗口腔免疫细菌感染的水性口腔喷雾剂，包括：1.天然衍生的二碱性氨基酸衍生物，2.天然甜味剂，其抑制细菌粘附到口腔，和3.可选地，天然风味和 /或天然染料4.任选地，修饰以吸收上述口腔水溶液的特定组分的口罩保护表面，以便与未修改的口罩表面相比，能够在抑制表面上的微生物生长和与口腔表面接触时使口罩更有效地加时间。
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公开(公告)号：US08926997B1
公开(公告)日：2015-01-06
申请号：US12798479
申请日：2010-04-05
IPC分类号： A01N25/00
CPC分类号： A01N25/30 , A23B4/10 , A23B4/20 , A23L3/3481 , C07C57/04 , C07C229/26 , C07C279/14 , A01N31/08 , A01N31/16 , A01N33/12 , A01N37/46 , A01N43/38 , A01N43/40 , A01N43/50 , A01N47/44
摘要： A polymeric biocidal salt is prepared from two components. The first component comprises a biocidal anionic or cationic monomeric, dendrimeric or polymeric ion. The second component comprises a dendrimeric or polymeric anion or cation having insignificant biocidal activity and a number average molecular weight of at least about 500. The second component will be cationic in nature when the first component is anionic in nature and anionic in nature when the first component is cationic in nature. The salt is further characterized as partially dissolving when exposed to an aqueous medium, thereby: (a) releasing sufficient biocidal ion to exceed the MIC or MBIC of a target bacteria sought to be controlled; and (b) leaving a reservoir of undissolved salt capable of being further dissolved and releasing additional biocidal ion as the biocidal ion is consumed or is otherwise removed from the environment encompassing the target bacteria.
摘要翻译： 聚合物杀生物剂盐由两种组分制备。 第一组分包括杀生物阴离子或阳离子单体，树枝状或聚合离子。 第二组分包括具有不显着的杀生物活性和数均分子量至少约500的树状聚合或聚合阴离子或阳离子。当第一组分在本质上是阴离子的时，第二组分本质上是阳离子的，当第一组分本质上是阴离子时，当第一组分 组分在本质上是阳离子的。 盐被进一步表征为当暴露于水性介质时部分溶解，从而：（a）释放足够的杀生物离子以超过试图控制的目标细菌的MIC或MBIC; 和（b）当存在杀生物离子被消耗或者从包含目标细菌的环境中除去时，留下能溶解的未溶解的盐的储存器并释放另外的杀生物离子。
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公开(公告)号：US20120328544A1
公开(公告)日：2012-12-27
申请号：US13600935
申请日：2012-08-31
IPC分类号： A61K31/14 , A61K31/223 , A61K8/92 , A61Q3/00 , A61P17/00 , A61P17/10 , A61Q19/00 , A61Q15/00 , A61K31/60 , A61P31/04
摘要： A dermatological composition for application to the skin or nails comprises a salt of a cation and an anion. The cation is derived from a monomeric or polymeric molecule that will generate an amidine moiety, a guanidine moiety or a biguanide moiety. The anion is derived from a monomeric or polymeric molecule that will generate a carboxylic acid moiety. The composition may be prepared by a metathesis or acid-base reaction.
摘要翻译： 用于皮肤或指甲的皮肤病学组合物包含阳离子和阴离子的盐。 阳离子衍生自将产生脒部分，胍部分或双胍部分的单体或聚合物分子。 阴离子衍生自将产生羧酸部分的单体或聚合物分子。 组合物可以通过复分解或酸碱反应来制备。
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公开(公告)号：US06759453B2
公开(公告)日：2004-07-06
申请号：US09970435
申请日：2001-10-03
IPC分类号： C08L9500
摘要： The invention comprises polymers which have been functionalized so as to be able to chemically react with polyamines to form adducts containing at least one or more groups consisting of amino, amido, imino, imido, or imidazloyl. Furthermore, the invention teaches processes to prepare these adducts by solution, melt or in-situ methods. A further embodiment of the invention pertains to the use of polyolefin plastomers or elastomers, elastomeric polyethylene-polypropylene, compositions or interpolymers of styrene-&agr; olefins, which have been chemically modified so that they react with polyamines to confer to asphalt significantly improved desired chemical and physical properties.
摘要翻译： 本发明包括已经被官能化以便能够与多胺化学反应以形成包含至少一个或多个由氨基，酰胺基，亚氨基，亚氨基或咪唑基组成的基团的加合物的聚合物。 此外，本发明教导了通过溶液，熔融或原位方法制备这些加合物的方法。 本发明的另一个实施方案涉及聚烯烃塑性体或弹性体，弹性聚乙烯 - 聚丙烯，苯乙烯-α烯烃的组合物或共聚物的用途，其已被化学改性，使得它们与多胺反应以赋予沥青以显着改善所需的化学品和 物理性质。
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公开(公告)号：US06585961B1
公开(公告)日：2003-07-01
申请号：US10016611
申请日：2001-11-30
申请人： Richard F. Stockel
发明人： Richard F. Stockel
IPC分类号： A61K716
CPC分类号： A61Q11/00 , A61K8/0291 , A61K8/33 , A61K8/34 , A61K8/347 , A61K8/37 , A61K8/39 , A61K8/44 , A61K8/442 , A61K8/463 , A61K8/4913 , A61K8/55 , A61K8/86 , A61K8/90 , A61K31/05 , A61K31/352 , A61K31/60 , A61K2800/413 , A61K2800/51 , B82Y5/00 , Y02A50/406 , A61K2300/00
摘要： Aqueous antimicrobial and biofilm removal compositions, comprising essential oils and certain cationic, anionic, amphoteric or non-ionic surfactants individually or in combination having an hydrophile-lipophile balance (HLB) of about 16 or above are effective oral mouthwashes and topical antimicrobial solutions. Optionally C2, C3, benzyl, 3-phenylpropanol or 2-phenylethanol alcohols can be added singularly or in combination from about 2 to about 20v/w %. Other optically ingredients include antimicrobial enhances and biofilm removal agents e.g., chelating compounds and certain organic acids.
摘要翻译： 包含精油和某些阳离子，阴离子，两性或非离子表面活性剂的水性抗微生物和生物膜去除组合物是单独或组合具有约16或更高亲水亲油平衡（HLB）的有效口服漱口剂和局部抗微生物溶液。 任选地，C2，C3，苄基，3-苯基丙醇或2-苯基乙醇醇可以单独或组合加入约2至约20v / w％。其它光学成分包括抗微生物增强剂和生物膜去除剂，例如螯合化合物和某些有机酸 。
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公开(公告)号：US4536571A
公开(公告)日：1985-08-20
申请号：US484874
申请日：1983-04-14
CPC分类号： C07F15/0093 , C07H23/00
摘要： The toxic effects of platinum compounds used in chemotherapy can be negated by the use of a selenium-containing compound. A new selenium-containing platinum compound has been found to be useful as a so-called platinum compound type anti-cancer medicine which can self-detoxify platinum toxicity.
摘要翻译： 化学治疗中使用的铂化合物的毒性作用可以通过使用含硒化合物来消除。 已经发现新的含硒铂化合物可用作能够自我解毒铂毒性的所谓的铂化合物型抗癌药物。
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公开(公告)号：US4469503A
公开(公告)日：1984-09-04
申请号：US481647
申请日：1983-04-04
申请人： Richard F. Stockel
发明人： Richard F. Stockel
摘要： The invention relates to a fertilizer composition which comprises coal ash, and a relatively water insoluble polymer capable of gradually decomposing to slowly release nitrogen polymerized uniformly on said coal ash. The polymer is formed by the in situ polymerization of an aldehyde and a polymerizable organic nitrogen containing compound capable of reacting with two or more equivalents of said aldehyde in the presence of an acid. The coal can be fly ash, bottom ash or boiler slag and can be derived from anthracite, bituminous or subbituminous coal or from lignite coal. The acid can be phosphoric acid, the aldehyde formaldehyde and the polymerizable organic nitrogen containing compound urea.
摘要翻译： 本发明涉及包含煤灰的肥料组合物和能够逐渐分解以缓慢释放在所述煤灰上均匀聚合的氮的相对不溶于水的聚合物。 聚合物通过在酸的存在下，能够与两种或更多当量的所述醛反应的醛和可聚合的含有机氮化合物的原位聚合而形成。 煤可以是飞灰，底灰或锅炉渣，可以来自无烟煤，烟煤或次烟煤或褐煤。 酸可以是磷酸，醛甲醛和可聚合的含有机氮的化合物脲。
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公开(公告)号：US07276109B2
公开(公告)日：2007-10-02
申请号：US10813462
申请日：2004-03-30
CPC分类号： B41N3/08
摘要： Piling due to ink, paper fibers and/or clay fillers occurs frequently during an offset printing process, resulting in the deterioration in print quality and lost manual time due to the necessity to clean the equipment. It has been experimentally found that small quantities of certain high molecular weight polyethylene oxide polymers can alleviate this serious problem. However, the overall effectiveness will depend on the concentration of the total make-up of component in the fountain solution.
摘要翻译： 由于油墨，纸纤维和/或粘土填料在胶版印刷过程中经常发生打桩，导致打印质量下降，并且由于需要清洁设备而损失手动时间。 实验发现，少量某些高分子量聚环氧乙烷聚合物可以缓解这个严重问题。 然而，整体效能将取决于喷泉溶液中组分的总组成的浓度。
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公开(公告)号：US4891423A
公开(公告)日：1990-01-02
申请号：US325872
申请日：1989-03-20
申请人： Richard F. Stockel
发明人： Richard F. Stockel
CPC分类号： A61L2/0088 , A01N47/44 , A61L12/142 , C08G73/00 , C08G73/024
摘要： Linear, polymeric polyoxyalkylenediamine biguanide or water soluble salt thereof. The biguanide is useful as a biocide in bactericidal and fungicidal compositions and is especially useful as the active ingredient in ophthalmic compositions.
摘要翻译： 线性聚合物，聚氧化亚烷基二胺双胍或其水溶性盐。 双胍可用作杀菌和杀真菌组合物中的杀生物剂，并且特别用作眼用组合物中的活性成分。
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20.发明授权Use of selenium-containing compounds for negating the toxic effects of gold compounds used in the treatment of rheumatoid arthritis, and a novel selenium-containing gold compound and use thereof as an anti-rheumatoid arthritis medicine 失效使用含硒化合物来抵消用于治疗类风湿性关节炎的金化合物的毒性作用，以及新颖的含硒金化合物及其作为抗类风湿关节炎药物的用途
公开(公告)号：US4680286A
公开(公告)日：1987-07-14
申请号：US735424
申请日：1985-04-09
CPC分类号： C07H23/00 , A61K33/04 , A61K33/24 , C07C391/00 , C07F9/5045
摘要： The toxic effects of gold compounds used in the treatment of rheumatoid arthritis can be negated by the use of a selenium-containing compound. A new selenium-containing gold compound has been found to be useful as a gold compound type anti-rheumatoid arthritis medicine which can self-detoxify gold toxicity.
摘要翻译： PCT No.PCT / US83 / 01239 Sec。 371日期：1985年4月9日 102（e）1985年4月9日PCT 1983年8月10日提交。用于治疗类风湿性关节炎的金化合物的毒性作用可以通过使用含硒化合物而被否定。 已经发现新的含硒金化合物可用作金化合物类抗风湿性关节炎药物，其可以自我解毒金毒性。
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