公开(公告)号：US06287577B1

公开(公告)日：2001-09-11

申请号：US08967972

申请日：1997-11-12

申请人： Peter William Beerse ,  Jeffrey Michael Morgan ,  Kathleen Grieshop Baier ,  Theresa Anne Bakken ,  Wei Cen ,  Mannie Lee Clapp ,  Raphael Warren

发明人： Peter William Beerse ,  Jeffrey Michael Morgan ,  Kathleen Grieshop Baier ,  Theresa Anne Bakken ,  Wei Cen ,  Mannie Lee Clapp ,  Raphael Warren

IPC分类号： A61K700

CPC分类号： A61Q19/00 ,  A61K8/347 ,  A61K8/365 ,  A61K8/463 ,  A61Q17/005

摘要： The present invention relates to a leave-on antimicrobial composition comprising from about 0.001% to about 5% of an antimicrobial active; from about 0.05% to about 10% of an anionic surfactant; from about 0.1% to about 10% of a proton donating agent; and from about 0% to about 99.85% of water; wherein the composition is adjusted to a pH of from about 3.0 to about 6.0; wherein the leave-on antimicrobial composition has a Gram Positive Residual Effectiveness Index of greater than about 0.5; and wherein the leave-on antimicrobial composition has a Mildness Index of greater than 0.3. The invention also encompasses methods for cleansing skin and providing residual effectiveness versus Gram positive bacteria using these products.

摘要翻译： 本发明涉及一种留下抗微生物组合物，其包含约0.001％至约5％的抗微生物活性物质; 约0.05％至约10％的阴离子表面活性剂; 约0.1％至约10％的质子供体剂; 和约0％至约99.85％的水; 其中将组合物调节至约3.0至约6.0的pH; 其中所述留置抗微生物组合物具有大于约0.5的革兰氏阳性残留有效性指数; 并且其中所述留置的抗微生物组合物具有大于0.3的温和指数。 本发明还包括使用这些产品的用于清洁皮肤并提供残留效力的革兰氏阳性细菌的方法。

公开(公告)号：US06284259B1

公开(公告)日：2001-09-04

申请号：US08969057

申请日：1997-11-12

申请人： Peter William Beerse ,  Jeffrey Michael Morgan ,  Kathleen Grieshop Baier ,  Theresa Anne Bakken ,  Wei Cen ,  Mannie Lee Clapp ,  Raphael Warren

发明人： Peter William Beerse ,  Jeffrey Michael Morgan ,  Kathleen Grieshop Baier ,  Theresa Anne Bakken ,  Wei Cen ,  Mannie Lee Clapp ,  Raphael Warren

IPC分类号： A61K750

CPC分类号： A61Q17/005 ,  A61K8/0208

摘要： The present invention relates to an antimicrobial wipe comprising a porous or absorbent sheet impregnated with an antimicrobial cleansing composition, wherein the antimicrobial cleansing composition comprises from about 0.001% to about 5.0%, by weight of the antimicrobial cleansing composition, of an antimicrobial active; from about 0.05% to about 10%, by weight of the antimicrobial cleansing composition, of an anionic surfactant; from about 0.1% to about 10%, by weight of the antimicrobial cleansing composition, of a proton donating agent; and from about 3% to about 99.85%, by weight of the antimicrobial cleansing composition, water; wherein the composition is adjusted to a pH of from about 3.0 to about 6.0; wherein the antimicrobial cleansing composition has a Gram Positive Residual Effectiveness Index of greater than about 0.5; and wherein the antimicrobial cleansing composition has a Mildness Index of less than about 0.3. The invention also encompasses methods for cleansing skin and providing residual effectiveness versus Gram positive bacteria using these products.

摘要翻译： 本发明涉及一种抗微生物擦拭物，其包括浸渍有抗微生物清洁组合物的多孔或吸收性片材，其中所述抗微生物清洁组合物包含抗微生物清洁组合物的约0.001％至约5.0％的抗微生物活性成分; 约0.05％至约10％的抗微生物清洁组合物;阴离子表面活性剂; 约0.1重量％至约10重量％的抗微生物清洁组合物;质子供体剂; 和约3％至约99.85％的抗微生物清洁组合物，水; 其中将组合物调节至约3.0至约6.0的pH; 其中所述抗微生物清洁组合物具有大于约0.5的革兰氏阳性残留有效性指数; 并且其中所述抗微生物清洁组合物的温和指数小于约0.3。 本发明还包括使用这些产品的用于清洁皮肤并提供残留效力的革兰氏阳性细菌的方法。

公开(公告)号：US06190675B1

公开(公告)日：2001-02-20

申请号：US08969049

申请日：1997-11-12

申请人： Peter William Beerse ,  Jeffrey Michael Morgan ,  Kathleen Grieshop Baier ,  Wei Cen ,  Theresa Anne Bakken ,  Mannie Lee Clapp ,  Raphael Warren

发明人： Peter William Beerse ,  Jeffrey Michael Morgan ,  Kathleen Grieshop Baier ,  Wei Cen ,  Theresa Anne Bakken ,  Mannie Lee Clapp ,  Raphael Warren

IPC分类号： A61K600

CPC分类号： A61K8/347 ,  A61K8/36 ,  A61K8/362 ,  A61K8/365 ,  A61K8/368 ,  A61K8/42 ,  A61K8/4933 ,  A61Q5/02 ,  A61Q17/005 ,  A61Q19/10 ,  Y10S514/975

摘要： The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.001% to about 5% of an antimicrobial active, from about 1% to about 80% of an anionic surfactant, from about 0.1% to about 12% of a proton donating agent; and from about 3% to about 98.899% of water, wherein the composition is adjusted to a pH of from about 3.0 to about 6.0, wherein the rinse-off antimicrobial cleansing composition has a Gram Positive Residual Effectiveness Index of greater than about 1.8, and wherein the rinse-off antimicrobial cleansing composition has a Mildness Index of greater than 0.3. The invention also encompasses methods for cleansing skin and providing residual effectiveness versus Gram positive bacteria using these products.

摘要翻译： 本发明涉及一种漂洗抗微生物清洁组合物，其包含约0.001％至约5％的抗微生物活性剂，约1％至约80％的阴离子表面活性剂，约0.1％至约12％的质子 捐赠代理人 和约3％至约98.899％的水，其中将组合物调节至约3.0至约6.0的pH，其中冲洗抗微生物清洁组合物具有大于约1.8的革兰氏阳性残留效力指数，以及 其中所述洗涤抗微生物清洁组合物的温和指数大于0.3。 本发明还包括使用这些产品的用于清洁皮肤并提供残留效力的革兰氏阳性细菌的方法。

公开(公告)号：US20120220510A1

公开(公告)日：2012-08-30

申请号：US13467107

申请日：2012-05-09

申请人： Mannie Lee Clapp ,  Karl Shiqing Wei ,  Christopher Garrett Anderson

发明人： Mannie Lee Clapp ,  Karl Shiqing Wei ,  Christopher Garrett Anderson

IPC分类号： A61K8/04 ,  A61Q19/10

CPC分类号： A61K8/03 ,  A61K8/0295 ,  A61K2800/43 ,  A61Q19/10

摘要： A multi-phase personal cleansing composition comprising: (a) a structured aqueous cleansing phase comprising a surfactant and water; and (b) at least one additional, non-lamellar aqueous phase; wherein at least one of said structured aqueous cleansing phase and said additional aqueous phase comprises at least one non-migrating colorant, said non-migrating colorant comprising a c Log P value of at least about 2; and wherein said structured aqueous cleansing phase and said additional aqueous phase are packaged in physical contact with one another.

摘要翻译： 一种多相个人清洁组合物，其包含：（a）包含表面活性剂和水的结构化含水清洁相; 和（b）至少一个另外的非层状水相; 其中所述结构化含水清洁相和所述另外的水相中的至少一个包含至少一种非迁移性着色剂，所述非迁移性着色剂包含至少约2的c Log P值; 并且其中所述结构化含水清洁相和所述附加水相彼此物理接触包装。

公开(公告)号：US08187580B2

公开(公告)日：2012-05-29

申请号：US10695283

申请日：2003-10-28

申请人： Robert Richard Dykstra ,  Lois Sara Gallon ,  Mannie Lee Clapp

发明人： Robert Richard Dykstra ,  Lois Sara Gallon ,  Mannie Lee Clapp

IPC分类号： C08L95/00 ,  C09D5/08 ,  A61K8/00

CPC分类号： A61Q19/00 ,  A61K8/0204 ,  A61K8/0241 ,  A61K8/35 ,  A61K8/37 ,  A61K8/8152 ,  A61K8/8158 ,  A61K2800/56 ,  A61K2800/654 ,  A61Q5/02 ,  A61Q19/10

摘要： Benefit agent delivery systems, compositions incorporating such benefit agent delivery systems, and methods for making the delivery system in the compositions are provided. The benefit agent delivery systems of the present invention employ polymer particles having affinities for selected benefit agents, such as perfume, to form the polymeric assisted benefit agent delivery systems, which can effectively deposit benefit agents onto, onto the surface of a substrate, e.g., fabrics being laundered, hard surfaces, hair, skin or nails.

摘要翻译： 提供了益处剂递送系统，包含这种有益剂递送系统的组合物以及用于在组合物中制备递送系统的方法。 本发明的有益剂递送系统使用对选定的有益剂如香料具有亲和力的聚合物颗粒，以形成聚合物辅助有益剂递送系统，其可有效地将有益剂沉积到基底表面上，例如， 织物被洗涤，硬表面，头发，皮肤或指甲。

公开(公告)号：US08147853B2

公开(公告)日：2012-04-03

申请号：US11057957

申请日：2005-02-15

申请人： Rebecca Ann Taylor ,  Mannie Lee Clapp ,  Qing Stella ,  John Christopher Wesner ,  Cynthia Ann Garza

发明人： Rebecca Ann Taylor ,  Mannie Lee Clapp ,  Qing Stella ,  John Christopher Wesner ,  Cynthia Ann Garza

IPC分类号： A61K8/18

CPC分类号： A61K8/02 ,  A61K8/27 ,  A61K8/29 ,  A61Q19/10

摘要： A rinsable personal care composition includes (a) 0 to 75 weight percent of a composition surfactant; (b) 0.01 to 99 weight percent of a skin benefit agent or emollient; (c) 0.01 to 20 weight percent of a hydrophobically modified non-platelet particle; and (d) 0 to 99% water.

摘要翻译： 可洗涤的个人护理组合物包含（a）0至75重量％的组合物表面活性剂; （b）0.01至99重量％的皮肤有益剂或润肤剂; （c）0.01-20重量％的疏水改性非血小板颗粒; 和（d）0至99％的水。

公开(公告)号：US06280758B1

公开(公告)日：2001-08-28

申请号：US09294574

申请日：1999-04-20

申请人： Raphael Warren ,  Mannie Lee Clapp

发明人： Raphael Warren ,  Mannie Lee Clapp

IPC分类号： A01N2500

CPC分类号： A61Q19/10 ,  A61K8/0208 ,  A61K8/347 ,  A61K8/42 ,  A61K8/463 ,  A61K8/731 ,  A61K8/8147 ,  A61K8/8152 ,  A61K2800/5424 ,  A61Q17/005 ,  A61Q19/00

摘要： The present invention relates to personal care compositions comprising from about 0.5% to about 80% of a surfactant, from about 0.1% to about 12% of a polymeric acid; and from about 3% to about 98.899% of water, wherein the composition is adjusted to a pH of from about 3.0 to about 6.0.

摘要翻译： 本发明涉及包含约0.5％至约80％的表面活性剂，约0.1％至约12％的聚合酸的个人护理组合物; 和约3％至约98.899％的水，其中将组合物调节至约3.0至约6.0的pH。

公开(公告)号：US08563491B2

公开(公告)日：2013-10-22

申请号：US11367815

申请日：2006-03-03

申请人： Timothy Woodrow Coffindaffer ,  Mannie Lee Clapp ,  Dennis Eugene Kuhlman ,  Kenneth Eugene Kyte, III ,  Daniel Burton Sears ,  Barbara Kay Williams

发明人： Timothy Woodrow Coffindaffer ,  Mannie Lee Clapp ,  Dennis Eugene Kuhlman ,  Kenneth Eugene Kyte, III ,  Daniel Burton Sears ,  Barbara Kay Williams

IPC分类号： A61K8/00

CPC分类号： A61K8/37 ,  A61K8/31 ,  A61K8/375 ,  A61K8/416 ,  A61K8/92 ,  A61K8/922 ,  A61Q1/14 ,  A61Q5/02 ,  A61Q19/10

摘要： Methods of cleansing skin comprise the steps of contacting the skin with a cleansing compositions comprising a fatty ester in combination with a lipid, and either rinsing the composition from the skin with water or wiping the composition from the skin with a dry or damp substrate. The cleansing compositions can comprise at least 8%, by weight of the composition, of fatty ester and/or further comprise a nonionic surfactant and less than about 50%, by weight of the composition, of an alcohol solvent such as ethanol, isopropanol, or mixtures thereof. The methods and compositions provide skin cleansing and hydration benefits.

摘要翻译： 清洁皮肤的方法包括使皮肤与包含与脂质组合的脂肪酯的清洁组合物接触的步骤，并用水从皮肤上漂洗组合物或用干燥或潮湿的底物从皮肤上擦拭组合物。 清洁组合物可以包含至少8重量％的组合物的脂肪酸酯和/或进一步包含非离子表面活性剂和小于组合物重量的约50％的醇溶剂如乙醇，异丙醇， 或其混合物。 该方法和组合物提供皮肤清洁和水合作用。

公开(公告)号：US08202319B2

公开(公告)日：2012-06-19

申请号：US13095731

申请日：2011-04-27

申请人： William Randal Belcher ,  Mannie Lee Clapp ,  Saswati Datta ,  Magda El-Nokaly ,  Sandra Lou Murawski ,  Steven Hardy Page ,  Sohini Paldey ,  Ronald Ray Warner ,  Raphael Warren

发明人： William Randal Belcher ,  Mannie Lee Clapp ,  Saswati Datta ,  Magda El-Nokaly ,  Sandra Lou Murawski ,  Steven Hardy Page ,  Sohini Paldey ,  Ronald Ray Warner ,  Raphael Warren

IPC分类号： A61F2/10 ,  B32B3/00 ,  B32B33/00 ,  B32B27/40 ,  C07C211/21 ,  C07C33/02 ,  C07C22/00 ,  C07C11/00 ,  C09D7/00

CPC分类号： C08J7/065 ,  A61L27/28 ,  A61L27/50 ,  A61L2400/18 ,  B82Y30/00 ,  C08J2375/04 ,  Y10T428/24479 ,  Y10T428/24802 ,  Y10T428/26 ,  Y10T428/31551 ,  Y10T442/2525

摘要： Article of manufacture comprising a substrate and a coating layer. The coating layer comprises at least one coating material, and is stably affixed to the substrate to form a stable, coated surface. The coated surface has a texture that mimics the topography of mammalian keratinous tissue and demonstrates at least one physical property representative of mammalian keratinous tissue, selected from the group consisting of a total surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a dispersive component of the surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a polar component of the total surface energy of from about 1 mJ/m2 to about 14 mJ/m2, a zeta-potential at a pH of about 5.0 of from about −40 mV to about 30 mV, and combinations thereof.

摘要翻译： 包括基材和涂层的制品。 涂层包括至少一种涂层材料，并且稳定地固定到基底上以形成稳定的涂覆表面。 涂覆的表面具有模拟哺乳动物角质组织的形貌的纹理，并且显示代表哺乳动物角质组织的至少一种物理性质，其选自总表面能为约15mJ / m 2至约50mJ / m 2 表面能的分散组分为约15mJ / m 2至约50mJ / m 2，总表面能的极性分数为约1mJ / m 2至约14mJ / m 2，ζ电位为 大约5.0的pH为约-40mV至约30mV，及其组合。

公开(公告)号：US20110202134A1

公开(公告)日：2011-08-18

申请号：US13095731

申请日：2011-04-27

申请人： William Randal Belcher ,  Mannie Lee Clapp ,  Saswati Datta ,  Magda El-Nokaly ,  Sandra Lou Murawski ,  Steven Hardy Page ,  Sohini Paldey ,  Ronald Ray Warner ,  Raphael Warren

发明人： William Randal Belcher ,  Mannie Lee Clapp ,  Saswati Datta ,  Magda El-Nokaly ,  Sandra Lou Murawski ,  Steven Hardy Page ,  Sohini Paldey ,  Ronald Ray Warner ,  Raphael Warren

IPC分类号： A61F2/10 ,  B32B3/00 ,  B32B33/00 ,  C07C211/21 ,  C07C33/02 ,  C07C22/00 ,  C09D7/00 ,  B32B27/40 ,  C07C11/00

CPC分类号： C08J7/065 ,  A61L27/28 ,  A61L27/50 ,  A61L2400/18 ,  B82Y30/00 ,  C08J2375/04 ,  Y10T428/24479 ,  Y10T428/24802 ,  Y10T428/26 ,  Y10T428/31551 ,  Y10T442/2525

摘要： Article of manufacture comprising a substrate and a coating layer. The coating layer comprises at least one coating material, and is stably affixed to the substrate to form a stable, coated surface. The coated surface has a texture that mimics the topography of mammalian keratinous tissue and demonstrates at least one physical property representative of mammalian keratinous tissue, selected from the group consisting of a total surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a dispersive component of the surface energy of from about 15 mJ/m2 to about 50 mJ/m2, a polar component of the total surface energy of from about 1 mJ/m2 to about 14 mJ/m2, a zeta-potential at a pH of about 5.0 of from about −40 mV to about 30 mV, and combinations thereof.

摘要翻译： 包括基材和涂层的制品。 涂层包括至少一种涂层材料，并且稳定地固定到基底上以形成稳定的涂覆表面。 涂覆的表面具有模拟哺乳动物角质组织的形貌的纹理，并且显示代表哺乳动物角质组织的至少一种物理性质，其选自总表面能为约15mJ / m 2至约50mJ / m 2 表面能的分散组分为约15mJ / m 2至约50mJ / m 2，总表面能的极性分数为约1mJ / m 2至约14mJ / m 2，ζ电位为 大约5.0的pH为约-40mV至约30mV，及其组合。