Leptin promoter polymorphisms and uses thereof
    11.
    发明申请
    Leptin promoter polymorphisms and uses thereof 审中-公开
    瘦素启动子多态性及其用途

    公开(公告)号:US20050202484A1

    公开(公告)日:2005-09-15

    申请号:US11061942

    申请日:2005-02-19

    申请人: Stephen Moore

    发明人: Stephen Moore

    IPC分类号: C12Q1/68

    摘要: The present invention relates to single nucleotide polymorphisms (SNPs) in the leptin promoter, and to methods for the identification of animals carrying specific alleles of these SNPs that are associated with circulating leptin levels, feed intake, growth rate, body weight, carcass merit and carcass composition. The present invention provides oligonucleotides that can be used as primers and/or probes to amplify and/or detect these SNPs, and provides methods for selecting and grouping animals, in particular bovines, according to genotype.

    摘要翻译: 本发明涉及瘦素启动子中的单核苷酸多态性(SNP),以及用于鉴定携带与循环瘦素水平,采食量,生长速率,体重,胴体优点相关的这些SNP的特定等位基因的动物的方法 胴体组成 本发明提供可用作引物和/或探针以扩增和/或检测这些SNP的寡核苷酸,并提供根据基因型选择和分组动物,特别是牛的方法。

    Method and apparatus for overcharge protection using analog overvoltage detection
    13.
    发明申请
    Method and apparatus for overcharge protection using analog overvoltage detection 审中-公开
    使用模拟过电压检测的过充保护方法和装置

    公开(公告)号:US20050052159A1

    公开(公告)日:2005-03-10

    申请号:US10658641

    申请日:2003-09-09

    IPC分类号: H02J7/00

    CPC分类号: H02J7/0031 H02J2007/0037

    摘要: A protection circuit for a multi-cell lithium battery pack is disclosed. The protection circuit monitors and compares the battery pack voltage level and automatically disconnects the battery pack from a charging signal when a turn-off threshold level is reached. Overcharging is eliminated, while maximizing the amount of charge on the battery pack, and thus duration of use.

    摘要翻译: 公开了一种用于多单元锂电池组的保护电路。 当达到关闭阈值电平时,保护电路监视和比较电池组电压电平,并自动断开电池组与充电信号的连接。 消除过充电,同时使电池组上的电荷量最大化,从而使用持续时间。

    Process for the preparation of purine derivatives as antiviral agents
    14.
    发明授权
    Process for the preparation of purine derivatives as antiviral agents 失效
    用于制备作为抗病毒剂的嘌呤衍生物的方法

    公开(公告)号:US5220024A

    公开(公告)日:1993-06-15

    申请号:US588569

    申请日:1990-09-26

    CPC分类号: C07D473/00

    摘要: A process for the preparation of a compound of formula (A): ##STR1## wherein X is hydrogen, hydroxy, chloro, C.sub.1-6 alkoxy or phenyl C.sub.1-6 alkoxy and R.sub.a and R.sub.b are hydrogen, including acyl and phosphate derivatives thereof; which process comprises:i) the preparation of a compound of formula (I): ##STR2## wherein R.sub.1 is C.sub.1-6 alkyl, or phenyl C.sub.1-6 alkyl in which the phenyl group is optionally substituted; R.sub.2 is hydrogen, hydroxy, chlorine, C.sub.1-6 alkoxy, phenyl C.sub.1-6 alkoxy or amino; and R.sub.3 is halogen, C.sub.1-6 alkylthio, C.sub.1-6 alkylsulphonyl, azido, an amino group or a protected amino group, which process comprises the reaction of a compound of formula (II): ##STR3## with a compound of formula (VII): ##STR4## wherein Q is a leaving group, J is hydrogen or halo and R.sub.1 is as hereinbefore defined; to give a compound of formula (VIII): ##STR5## followed by reduction of the compound of formula (VIII) to give a compound of formula (I) as hereinbefore defined; and, as necessary or desired, interconverting variables R.sub.1, R.sub.2 and R.sub.3 to further values of R.sub.1, R.sub.2 and R.sub.3 ;(ii) the conversion of the resulting compound of formula (I) to a compound of formula (A) by converting variable R.sub.3, when other than amino, to amino, reducing the ester groups CO.sub.2 R.sub.1 to CH.sub.2 OH and optionally forming acyl or phosphate derivatives thereof, and as necessary or desired converting variable R.sub.2 in the compound of formula (I) to variable X in the compound of formula (A).

    METHOD AND SYSTEM FOR GENERATING DIGITAL CERTIFICATES AND CERTIFICATE SIGNING REQUESTS
    16.
    发明申请
    METHOD AND SYSTEM FOR GENERATING DIGITAL CERTIFICATES AND CERTIFICATE SIGNING REQUESTS 审中-公开
    产生数字证书和证书签名要求的方法和系统

    公开(公告)号:US20100138907A1

    公开(公告)日:2010-06-03

    申请号:US12326002

    申请日:2008-12-01

    IPC分类号: H04L9/32 G06F15/16 G06F17/00

    CPC分类号: H04L9/3263 H04L63/0823

    摘要: A certificate server is provided for issuing digital certificates to be used by a network resource and/or a client resource. The certificate server is configured to communicate with the network resource or the client resource to receive a certificate request. Upon receiving the certificate request, the certificate server may automate the process for authenticating the certificate request, validating the terms of the certificate request and digitally signing the certificate request. An authentication appliance may communicate with or be integrated within the certificate server. The certificate server includes a web service server, a certificate authority component, and a database that enable communication with either the network resource, client resource, or the authentication appliance to automate the administration process typically involved in receiving and signing a certificate request. The certificate authority component may sign the certificate request with a trusted root chain associated with the network resource.

    摘要翻译: 提供证书服务器用于发行要由网络资源和/或客户端资源使用的数字证书。 证书服务器被配置为与网络资源或客户端资源通信以接收证书请求。 证书服务器在收到证书请求后,可自动执行认证证书请求的过程,验证证书请求的条款并对证书请求进行数字签名。 身份验证设备可以与证书服务器通信或集成在证书服务器中。 证书服务器包括Web服务服务器,证书颁发机构组件和能够与网络资源,客户端资源或身份验证设备通信的数据库,以自动执行通常涉及到接收和签署证书请求的管理过程。 证书颁发机构组件可以使用与网络资源相关联的受信任的根链对证书请求进行签名。

    Method for pricing a trade
    17.
    发明申请
    Method for pricing a trade 有权
    交易定价方法

    公开(公告)号:US20050027658A1

    公开(公告)日:2005-02-03

    申请号:US10757940

    申请日:2004-01-15

    IPC分类号: G06Q10/00 G06F17/60

    摘要: A method for pricing a trade comprising providing a user input for entering trade data, providing a structure for receiving the trade data and then transmitting the structure to a pricing system. The structure, now populated with both the trade data and the pricing data, is received from the pricing system and the trade data and pricing information is displayed. Advantageously, the structure is encrypted prior to transmitting it to the pricing system and decrypted when received from the pricing system. The pricing system records the data and the pricing information, which may be automatically entered into a trading system if and when the user agrees.

    摘要翻译: 一种用于定价交易的方法,包括提供用于输入交易数据的用户输入,提供用于接收交易数据的结构,然后将结构发送到定价系统。 现在,从定价系统接收现在交易数据和定价数据的结构,并显示交易数据和定价信息。 有利的是,在将结构发送到定价系统之前对该结构进行加密,并在从定价系统接收到时对其进行解密。 定价系统记录数据和定价信息,如果用户同意,可以自动输入交易系统。

    Preparation of poly(arylene ether ketones)
    18.
    发明授权
    Preparation of poly(arylene ether ketones) 失效
    聚(亚芳基醚酮)的制备

    公开(公告)号:US4698393A

    公开(公告)日:1987-10-06

    申请号:US922781

    申请日:1986-10-23

    摘要: The preparation of poly(arylene ether ketones) by Friedel-Crafts polymerization, in the presence of a Lewis acid catalyst and a diluent, is conducted under conditions in which the polymer and/or its complex with the catalyst is suspended in the diluent during at least part of the polyreaction mixture if desired. The dispersant may be a polymer or an organic compound containing at least eight carbon atoms and is preferably a Lewis base. The dispersant preferably contains at least one molecular segment substantially compatible with the poly(arylene ether ketone) or its complex with the Lewis acid and substantially incompatible with the diluent and at least one molecular segment substantially compatible with the diluent and substantially incompatible with the poly(arylene ether ketone) or its complex with the Lewis acid.

    摘要翻译: 在路易斯酸催化剂和稀释剂存在下,通过Friedel-Crafts聚合法制备聚(亚芳基醚酮)是在聚合物和/或其与催化剂的络合物悬浮在稀释剂中的条件下进行的 如果需要,最少部分的聚反应混合物。 分散剂可以是聚合物或含有至少8个碳原子的有机化合物,优选为路易斯碱。 分散剂优选含有至少一个基本上与聚(亚芳基醚酮)或其与路易斯酸的络合物相容的分子片段,并且与稀释剂基本上不相容,并且至少一个分子片段基本上与稀释剂相容并且与聚( 亚芳基醚酮)或其与路易斯酸的络合物。