公开(公告)号：US5399767A

公开(公告)日：1995-03-21

申请号：US194625

申请日：1994-02-08

申请人： Rikuo Nasu ,  Motohiko Hamaguchi

发明人： Rikuo Nasu ,  Motohiko Hamaguchi

IPC分类号： B01J23/44 ,  C07B61/00 ,  C07C209/68 ,  C07C209/74 ,  C07C211/52 ,  C07C255/58

CPC分类号： C07C209/74 ,  C07C209/68

摘要： A process for producing 3,5-difluoroaniline, which comprises reacting a benzonitrile compound of the formula (I): ##STR1## wherein each of X.sub.1, X.sub.2 and X.sub.3 is hydrogen, chlorine, bromine or a cyano group, provided that at least one of X.sub.1 to X.sub.3 is a cyano group, with a mineral acid for hydrolysis and decarboxylation to obtain an aniline compound of the formula (II): ##STR2## wherein each of X.sub.4, X.sub.5 and X.sub.6 is hydrogen, chlorine or bromine, provided that at least one of X.sub.4 to X.sub.6 is hydrogen, and in the case of a compound of the formula (II) wherein X.sub.4, X.sub.5 and X.sub.6 are not simultaneously hydrogen, reacting such a compound with hydrogen in a presence of a catalyst for reduction to obtain 3,5 -difluoroaniline.

摘要翻译： 一种制备3,5-二氟苯胺的方法，其包括使式（I）的苄腈化合物：其中X1，X2和X3各自为氢，氯，溴或氰基，条件是 X1至X3中的至少一个为氰基，与无机酸进行水解和脱羧，得到式（II）的苯胺化合物：其中X 4，X 5和X 6各自为氢，氯 或溴，条件是X 4至X 6中的至少一个为氢，并且在式（II）化合物的情况下，其中X 4，X 5和X 6不同时为氢），使该化合物与氢在 用于还原的催化剂得到3,5-二氟苯胺。

公开(公告)号：US5491239A

公开(公告)日：1996-02-13

申请号：US144525

申请日：1993-11-02

申请人： Rikuo Nasu ,  Motohiko Hamaguchi ,  Hayato Ariyoshi

发明人： Rikuo Nasu ,  Motohiko Hamaguchi ,  Hayato Ariyoshi

IPC分类号： C07C209/74 ,  C07C253/30 ,  C07D213/61 ,  C07D213/73 ,  C07D213/85

CPC分类号： C07D213/73 ,  C07C209/74 ,  C07C253/30 ,  C07D213/61 ,  C07D213/85 ,  Y02P20/582

摘要： A method for halogenating an aromatic compound, which comprises reacting the aromatic compound of the formula (I): ##STR1## wherein X is a hydroxyl group, an amino group or an acylamino group, each of Z.sub.1 and Z.sub.2 is a hydrogen atom or a halogen atom, one of R and Y is a hydrogen atom and the other is a nitro group, a cyano group or a trifluoromethyl group, and Q is a nitrogen atom or --C(T).dbd. (wherein T is a hydrogen atom, a halogen atom, a nitro group, a cyano group or a trifluoromethyl group), with a halogenating agent to obtain a 3-halogenoaromatic compound of the formula (II): ##STR2## wherein one of R' and Y' is a halogen atom and the other is a nitro group, a cyano group or a trifluoromethyl group, and X, Z.sub.1, Z.sub.2 and Q are as defined above.

摘要翻译： 一种卤化芳族化合物的方法，其包括使式（I）的芳族化合物：其中X为羟基，氨基或酰氨基，其中Z 1和Z 2各自为氢 原子或卤素原子，R和Y中的一个是氢原子，另一个是硝基，氰基或三氟甲基，Q是氮原子或-C（T）=（其中T是氢 原子，卤素原子，硝基，氰基或三氟甲基）与卤化剂反应，得到式（II）的3-卤代芳香族化合物：其中R'和Y '是卤素原子，另一个是硝基，氰基或三氟甲基，X，Z 1，Z 2和Q如上所定义。

公开(公告)号：US5290944A

公开(公告)日：1994-03-01

申请号：US990276

申请日：1992-12-14

申请人： Rikuo Nasu ,  Taku Shimura ,  Isamu Katsuyama

发明人： Rikuo Nasu ,  Taku Shimura ,  Isamu Katsuyama

IPC分类号： C07B61/00 ,  C07D213/26 ,  C07D213/61 ,  C07D213/62

CPC分类号： C07D213/26 ,  C07D213/61

摘要： A method for producing a dichloromethylpyridine of the formula (II): ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 which are independent of one another, is a hydrogen atom, a halogen atom, an alkoxy group or a phenoxy group which may be substituted, provided that R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are not simultaneously hydrogen atoms, which comprises reacting a trichloromethylpyridine of the formula (I): ##STR2## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are as defined above, with a reducing agent, wherein:(1) a dialkyl phosphite or a trialkyl phosphite is used as the reducing agent, and the reaction is conducted in the presence of a basic substance and an alcohol solvent, or(2) a trialkyl phosphine or triphenyl phosphine is used as the reducing agent, and the reaction is conducted in the presence of an alcohol solvent.

摘要翻译： 制备式（II）的二氯甲基吡啶的方法：（*化学结构*）（II）其中R 1，R 2，R 3和R 4彼此独立地为氢原子，卤素原子，烷氧基 基团或可被取代的苯氧基，条件是R 1，R 2，R 3和R 4不同时为氢原子，其包括使式（I）的三氯甲基吡啶：（*化学结构*）（I） ，R3和R4如上定义，与还原剂反应，其中：（1）亚磷酸二烷基酯或亚磷酸三烷基酯用作还原剂，反应在碱性物质和醇溶剂的存在下进行， 或（2）使用三烷基膦或三苯基膦作为还原剂，反应在醇溶剂的存在下进行。

公开(公告)号：USH811H

公开(公告)日：1990-08-07

申请号：US322460

申请日：1989-03-13

申请人： Rikuo Nasu ,  Terumasa Komyoji ,  Toshio Nakajima ,  Kazumi Suzuki ,  Keiichiro Ito ,  Tekeshi Ohshima ,  Hideshi Yoshimura

发明人： Rikuo Nasu ,  Terumasa Komyoji ,  Toshio Nakajima ,  Kazumi Suzuki ,  Keiichiro Ito ,  Tekeshi Ohshima ,  Hideshi Yoshimura

IPC分类号： A01N43/50 ,  A01N47/14 ,  A01N47/34 ,  A01N47/38 ,  A01N53/00 ,  A01N55/00 ,  A01N57/12 ,  A01N59/20 ,  C07D233/90

CPC分类号： C07D233/90 ,  A01N43/50 ,  A01N63/04 ,  A01N59/20 ,  A01N57/12 ,  A01N55/00 ,  A01N53/00 ,  A01N47/38 ,  A01N47/34 ,  A01N47/14 ,  A01N47/04 ,  A01N43/90 ,  A01N43/80 ,  A01N43/653 ,  A01N43/40 ,  A01N37/36 ,  A01N37/34 ,  A01N37/24 ,  A01N2300/00

摘要： A biocidal composition containing, as active ingredients, at least one imidazole compound represented by formula (I): ##STR1## wherein R.sup.1 represents a phenyl group, a halogen-substituted phenyl group, an alkyl group, or a halogen-substituted alkyl group; and R.sup.2 represents a halogen atom, and at least one other specific compound. The combination of the compound represented by formula (I) and other specific compound can produce an unexpected effect in amount required and biocidal spectrum.

公开(公告)号：US4420618A

公开(公告)日：1983-12-13

申请号：US401744

申请日：1982-07-26

申请人： Isao Yokomichi ,  Takahiro Haga ,  Rikuo Nasu ,  Kuniaki Nagatani ,  Toshio Nakajima

发明人： Isao Yokomichi ,  Takahiro Haga ,  Rikuo Nasu ,  Kuniaki Nagatani ,  Toshio Nakajima

IPC分类号： B01J27/00 ,  B01J27/10 ,  B01J27/128 ,  B01J27/132 ,  B01J27/135 ,  C07B61/00 ,  C07D213/61 ,  C07D213/26

CPC分类号： C07D213/61

摘要： 5,6-Dichloro-.beta.-trifluoromethylpyridine or 2,5,6-trichloro-.beta.-trifluoromethylpyridine is produced by reacting 6-chloro-.beta.-trifluoromethylpyridine or 2,6-dichloro-.beta.-trifluoromethylpyridine with chlorine gas to chlorinate the 5-position of pyridine nucleus thereof:(1) at a temperature of 100.degree. C. to 250.degree. C. and at least sufficient amount of chlorine for the reaction;(2) in the presence of the catalyst of amount of at least 40% by weight (based on the 6-chloro or/and 2,6-dichloro-.beta.-trifluoromethylpyridine), the catalyst being chlorides a metallic element selected from the group consisting of iron, tungsten, molybdenum, titanium, and antimony.

摘要翻译： 通过6-氯-β-三氟甲基吡啶或2,6-二氯-α-三氟甲基吡啶与氯气反应生成5,6-二氯-β-三氟甲基吡啶或2,5,6-三氯-β-三氟甲基吡啶， 吡啶核的位置：（1）在100℃至250℃的温度和至少足够量的氯用于反应; （2）在催化剂存在下，至少40重量％（基于6-氯或/和2,6-二氯-β-三氟甲基吡啶），催化剂是氯化物，选自下组的金属元素 由铁，钨，钼，钛和锑组成。