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11.发明申请PEPTIDE FOR INHIBITION OF BINDING BETWEEN ANGIOPOIETIN-2 AND INTEGRIN AND USE THEREOF 审中-公开用于抑制血管平滑肌蛋白-2与整合素之间的结合的肽及其用途公开(公告)号：US20160101154A1
公开(公告)日：2016-04-14
申请号：US14919386
申请日：2015-10-21
Applicant: Samsung Electronics Co., Ltd.
Inventor： Sang Yeul Han , Chung Ho Kim , Kyung Eun Kim , Hyung-Chan Kim , Kwang-Hoon Lee , Hyo Seon Lee
IPC: A61K38/18 , C07K14/515
CPC classification number: A61K38/1891 , A61K38/00 , C07K14/00 , C07K14/001 , C07K14/515 , C07K2319/30 , C07K2319/70
Abstract: Angiopoietin-2 (Ang2) derived peptides, polypeptides, and peptide complexes, and a method for inhibition of binding between Ang2 and integrin and prevention and/or treatment of a disease caused by the activation of Ang2 or the binding between Ang2 and integrin using the peptide, polypeptides, and peptide complexes.
Abstract translation: 促血管生成素-2（Ang2）来源的肽，多肽和肽复合物，以及用于抑制Ang2与整联蛋白之间的结合的方法，以及预防和/或治疗由Ang2的活化引起的疾病或Ang2和整联蛋白之间的结合 肽，多肽和肽复合物。
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公开(公告)号：US20150337033A1
公开(公告)日：2015-11-26
申请号：US14721591
申请日：2015-05-26
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: C07K16/22 , G01N33/68 , C07K14/705 , C07K14/515 , A61K39/395 , A61K38/18
CPC classification number: C07K16/22 , A61K38/00 , A61K39/3955 , A61K2039/505 , C07K14/515 , C07K14/705 , C07K2317/24 , C07K2317/567 , C07K2317/622 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/6887 , G01N33/6893 , G01N2333/515
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
Abstract translation: 通过Ang2特异性结合血管发生诱导因子促血管生成素-2（Ang2）和与Tie2受体复合的抗Ang2抗体或其抗原结合片段及其使用方法。
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公开(公告)号：US20150079112A1
公开(公告)日：2015-03-19
申请号：US14446199
申请日：2014-07-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung Eun KIM , Sang Yeul Han , Gou Young Koh , Hyo Seon Lee , Chan Kim
CPC classification number: C07K16/28 , A61K38/17 , A61K45/06 , A61K2039/505 , C07K16/22 , C07K2317/32 , C07K2317/565 , C07K2317/74 , C07K2317/75 , C07K2317/77 , C07K2317/92
Abstract: A method of preventing or treating cancer using an anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes to a Tie2 receptor while bound with Ang2.
Abstract translation: 使用Ang2抗体或其抗原结合片段预防或治疗癌症的方法，所述抗Ang2抗体或其抗原结合片段特异性结合血管发生诱导因子促血管生成素-2（Ang2），并与Ang2结合时与Tie2受体复合。
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公开(公告)号：US11174309B2
公开(公告)日：2021-11-16
申请号：US15823272
申请日：2017-11-27
Applicant: Samsung Electronics Co., Ltd
Inventor： Kyung Eun Kim , Seung Ja Oh , Hyo Seon Lee , Sang Yeul Han
IPC: A61K39/395 , A61K39/00 , C07K16/22 , A61K38/18 , G01N33/74
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor and Ang2, and related methods and compositions.
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公开(公告)号：US20180273613A1
公开(公告)日：2018-09-27
申请号：US16004622
申请日：2018-06-11
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seok Kyun Kim , Sunghyun Kim , Sang Yeul Han , Seung Hyun Lee , Su Jin Kim , Yong In Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee
IPC: C07K16/22 , G01N33/68 , A61K39/395 , C07K14/705 , C07K14/515 , A61K39/00 , A61K38/00
CPC classification number: C07K16/22 , A61K38/00 , A61K39/3955 , A61K2039/505 , C07K14/515 , C07K14/705 , C07K2317/24 , C07K2317/567 , C07K2317/622 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/6887 , G01N33/6893 , G01N2333/515
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor through Ang2, and methods of using the same.
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Patent Agency Ranking
16.发明授权公开(公告)号：US09931400B2
公开(公告)日：2018-04-03
申请号：US14025403
申请日：2013-09-12
Applicant: Samsung Electronics Co., Ltd.
Inventor： Yun Ju Jeong , Kyung Ah Kim , Yun Jeong Song , Ji Min Lee , Hyo Seon Lee , Jae Hyun Choi , Saet Byoul Lee
IPC: A61K39/395 , A61K45/06 , C07K16/28
CPC classification number: A61K39/3955 , A61K45/06 , C07K16/2863 , C07K2317/24
Abstract: Provided is a method of combination therapy for prevention or treatment of c-Met-induced or angiogenesis factor-induced diseases including co-administering an angiogenesis inhibitor and an anti-c-Met antibody or an antigen-binding fragment thereof to a patient.
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公开(公告)号：US09828422B2
公开(公告)日：2017-11-28
申请号：US14446228
申请日：2014-07-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung Eun Kim , Seung Ja Oh , Hyo Seon Lee , Sang Yeul Han
CPC classification number: C07K16/22 , A61K38/1891 , A61K39/395 , A61K39/3955 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/74 , G01N2333/515 , G01N2333/71 , G01N2500/02
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor and Ang2, and related methods and compositions.
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公开(公告)号：US09527910B2
公开(公告)日：2016-12-27
申请号：US14322343
申请日：2014-07-02
Applicant: Samsung Electronics Co., Ltd.
Inventor： Yoon Sook Lee , Chung Ho Kim , Kyung Eun Kim , Hyung-Chan Kim , Kwang Hoon Lee , Hyo Seon Lee , Sang Yeul Han
CPC classification number: C07K16/22 , C07K2317/34 , C07K2317/76 , C07K2317/92 , G01N33/74 , G01N2333/515 , G01N2800/7014
Abstract: Provided are an anti-Ang-2 antibody or antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang-2), related compositions and pharmaceutical compositions, and methods for using such compositions and pharmaceutical compositions.
Abstract translation: 提供特异性结合血管发生诱导因子促血管生成素-2（Ang-2），相关组合物和药物组合物的抗Ang-2抗体或其抗原结合片段，以及使用这些组合物和药物组合物的方法。
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公开(公告)号：US09505841B2
公开(公告)日：2016-11-29
申请号：US14446199
申请日：2014-07-29
Inventor： Kyung Eun Kim , Sang Yeul Han , Gou Young Koh , Hyo Seon Lee , Chan Kim
CPC classification number: C07K16/28 , A61K38/17 , A61K45/06 , A61K2039/505 , C07K16/22 , C07K2317/32 , C07K2317/565 , C07K2317/74 , C07K2317/75 , C07K2317/77 , C07K2317/92
Abstract: A method of preventing or treating cancer using an anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes to a Tie2 receptor while bound with Ang2.
Abstract translation: 使用Ang2抗体或其抗原结合片段预防或治疗癌症的方法，所述抗Ang2抗体或其抗原结合片段特异性结合血管发生诱导因子促血管生成素-2（Ang2），并与Ang2结合时与Tie2受体复合。
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公开(公告)号：US20150030603A1
公开(公告)日：2015-01-29
申请号：US14446228
申请日：2014-07-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung Eun KIM , Seung Ja Oh , Hyo Seon Lee , Sang Yeul Han
IPC: C07K16/22 , A61K38/18 , G01N33/74 , A61K39/395
CPC classification number: C07K16/22 , A61K38/1891 , A61K39/395 , A61K39/3955 , A61K2039/505 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/74 , G01N2333/515 , G01N2333/71 , G01N2500/02
Abstract: An anti-Ang2 antibody or an antigen-binding fragment thereof that specifically binds to an angiogenesis-inducing factor Angiopoietin-2 (Ang2) and complexes with a Tie2 receptor and Ang2, and related methods and compositions.
Abstract translation: 特异性结合血管发生诱导因子促血管生成素-2（Ang2促血管素-2）和与Tie2受体和Ang2复合的抗Ang2抗体或其抗原结合片段，以及相关方法和组合物。
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