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公开(公告)号：US20140356366A1
公开(公告)日：2014-12-04
申请号：US14290447
申请日：2014-05-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho CHEONG , Seung Hyun Lee , Mi Young Cho , Young Jun Koh , Lin Powei , Christina Yi , Jae Woong Hwang
CPC classification number: C07K16/2863 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/53 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: A method of target membrane protein depletion comprising treating a cell with a dual binding molecule comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the cell comprises a cell membrane, and the driver membrane protein and target membrane protein are associated with the cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein; as well as related methods and compositions.
Abstract translation: 一种目标膜蛋白质耗尽的方法，包括用双重结合分子处理细胞，所述双重结合分子包含结合驱动膜蛋白的第一结合结构域和结合靶膜蛋白的第二结合结构域，其中所述细胞包含细胞膜，以及 驱动膜蛋白和靶膜蛋白与靶膜蛋白定位的细胞膜相关联，并且当双重结合分子的第一结合结构域结合驱动膜蛋白时，其被内化为细胞并降解; 以及相关方法和组成。
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公开(公告)号：US11155627B2
公开(公告)日：2021-10-26
申请号：US15494875
申请日：2017-04-24
Applicant: Samsung Electronics Co., Ltd.
Inventor： Hyung-Chan Kim , Kyung Eun Kim , Yoon Sook Lee , Mi Young Cho
Abstract: An anti-c-Met/anti-Ang2 bispecific antibody, a composition including the anti-c-Met/anti-Ang2 bispecific antibody, and a method of preventing and/or treating a cancer in a subject including administering the anti-c-Met/anti-Ang2 bispecific antibody to the subject.
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公开(公告)号：US10214593B2
公开(公告)日：2019-02-26
申请号：US14243751
申请日：2014-04-02
Applicant: SAMSUNG ELECTRONICS CO., LTD.
Inventor： Soo Yeon Jung , Yun Jeong Song , Mi Young Cho , Han Na Choi
Abstract: Disclosed are an anti-idiotype antibody that specifically binds to an idiotope site of an anti-c-Met antibody, the use of the anti-idiotype antibody for detecting the anti-c-Met antibody, and methods, polypeptides, polynucleotides, compositions, and vaccines related thereto.
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Patent Agency Ranking
公开(公告)号：US10000569B2
公开(公告)日：2018-06-19
申请号：US14692934
申请日：2015-04-22
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho Cheong , Jae Woong Hwang , Seung Hyun Lee , Powei Lin , Mi Young Cho
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K16/32 , C07K16/40 , C07K2317/31 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C12N15/09
Abstract: An anti-EGFR/anti-HER3 antibody or antigen binding fragment thereof, and a method of preventing and/or treating a cancer using the same.
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公开(公告)号：US09717715B2
公开(公告)日：2017-08-01
申请号：US14081886
申请日：2013-11-15
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seung Hyun Lee , Geun Woong Kim , Kyung Ah Kim , Hye Won Park , Ho Yeong Song , Young Mi Oh , Saet Byoul Lee , Ji Min Lee , Kwang Ho Cheong , Yun Ju Jeong , Mi Young Cho , Jae Hyun Choi , Yun Jeong Song , Yoon Aa Choi
IPC: A61K39/395 , A61K31/437 , A61K31/517 , A61K31/44 , C07K16/28 , C12N5/16
CPC classification number: A61K31/437 , A61K31/44 , A61K31/517 , A61K39/3955 , A61K39/39558 , C07K16/2863 , C07K2317/24 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2317/92 , C07K2319/30 , C12N5/163 , A61K2300/00
Abstract: A method for prevention or treatment of a cancer, comprising co-administering (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib or a combination thereof, to a subject in need thereof, and a pharmaceutical composition comprising (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib, or a combination thereof are provided.
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16.发明申请ANTI-CMET/ANTI-EGFR/ANTI-HER3 MULTIPECIFIC ANTIBODIES AND USE THEREOF 有权抗CMET /抗EGFR /抗-IV3多种抗体及其用途公开(公告)号：US20150322165A1
公开(公告)日：2015-11-12
申请号：US14692934
申请日：2015-04-22
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho Cheong , Jae Woong Hwang , Seung Hyun Lee , Powei Lin , Mi Young Cho
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/39558 , A61K2039/505 , A61K2039/507 , C07K16/32 , C07K16/40 , C07K2317/31 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C12N15/09
Abstract: An anti-EGFR/anti-HER3 antibody or antigen binding fragment thereof, and a method of preventing and/or treating a cancer using the same
Abstract translation: 抗EGFR /抗HER3抗体或其抗原结合片段，以及使用其的预防和/或治疗癌症的方法
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公开(公告)号：US20150030596A1
公开(公告)日：2015-01-29
申请号：US14444632
申请日：2014-07-28
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kwang Ho CHEONG , Young Jun Koh , Min-Kyung Kim , Powei Lin , Seung Hyun Lee , Jung Wook Lee , Mi Young Cho , Jae Woong Hwang
IPC: C07K16/28 , C07K14/705
CPC classification number: C07K16/2863 , C07K14/705 , C07K16/32 , C07K2317/24 , C07K2317/31 , C07K2317/53 , C07K2317/565 , C07K2317/567 , C07K2317/622 , C07K2317/73 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2318/20 , C07K2319/30 , C07K2319/33
Abstract: A bispecific chimeric protein including a designed ankyrin repeat protein (DARPin), and an IgG antibody, an scFv-Fc antibody fragment, or a combination thereof, linked to the DARPin; a method for treating or preventing cancer using the same; and related methods and compositions.
Abstract translation: 包含与DARPin连接的双特异性嵌合蛋白，包括设计的锚蛋白重复蛋白（DARPin）和IgG抗体，scFv-Fc抗体片段或其组合; 使用该方法治疗或预防癌症的方法; 以及相关方法和组成。
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公开(公告)号：US20140154251A1
公开(公告)日：2014-06-05
申请号：US14081917
申请日：2013-11-15
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seung Hyun LEE , Geun Woong Kim , Kyung Ah Kim , Hye Won Park , Ho Yeong Song , Young Mi Oh , Saet Byoul Lee , Ji Min Lee , Kwang Ho Cheong , Yun Ju Jeong , Mi Young Cho , Jae Hyun Choi , Yun Jeong Song , Yoon Aa Choi
IPC: C07K16/28
CPC classification number: C07K16/2863 , A61K2039/505 , C07K2317/24 , C07K2317/52 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/92
Abstract: An anti-c-Met antibody or antibody fragment and pharmaceutical composition comprising same, as well as a method for preventing and treating cancer by administering the antibody to a subject are provided.
Abstract translation: 提供了抗c-Met抗体或抗体片段及包含其的药物组合物，以及通过向受试者施用抗体来预防和治疗癌症的方法。
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