-
11.发明申请MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR 有权CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR的调节剂公开(公告)号：US20100113509A1
公开(公告)日：2010-05-06
申请号：US12605250
申请日：2009-10-23
申请人： Hayley Binch , Lev T.D. Fanning , Martyn Botfield , Peter D.J. Grootenhuis , Fredrick van Goor , Mehdi Michel Djamel Numa
发明人： Hayley Binch , Lev T.D. Fanning , Martyn Botfield , Peter D.J. Grootenhuis , Fredrick van Goor , Mehdi Michel Djamel Numa
IPC分类号： A61K31/439 , C07D453/04 , G01N33/53
CPC分类号： C07D401/14 , C07D487/08 , Y02P20/55
摘要： The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
摘要翻译： 本发明涉及囊性纤维化跨膜传导调节剂（“CFTR”）的调节剂，其组合物及其方法。 本发明还涉及使用CFTR的调节剂治疗疾病的方法。
-
公开(公告)号：US20130040986A1
公开(公告)日：2013-02-14
申请号：US13652056
申请日：2012-10-15
申请人： Hayley Binch , Lev T.D. Fanning , Martyn Botfield , Peter D.J. Grootenhuis , Fredrick Van Goor , Mehdi Michel Djamel Numa
发明人： Hayley Binch , Lev T.D. Fanning , Martyn Botfield , Peter D.J. Grootenhuis , Fredrick Van Goor , Mehdi Michel Djamel Numa
IPC分类号： A61K31/4709 , C07D487/08 , C12N5/071 , A61K31/46 , A61P11/00 , A61P11/06 , A61P1/16 , A61P3/00 , A61P1/00 , A61P15/08 , A61P35/00 , A61P3/10 , A61P25/28 , A61P25/16 , A61P25/14 , A61P25/00 , A61P19/10 , C07D451/02
CPC分类号： C07D401/14 , C07D487/08 , Y02P20/55
摘要： The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
摘要翻译： 本发明涉及囊性纤维化跨膜电导调节剂（CFTR）的调节剂，其组合物及其方法。 本发明还涉及使用CFTR的调节剂治疗疾病的方法。
-
公开(公告)号：US20120208841A1
公开(公告)日：2012-08-16
申请号：US13439379
申请日：2012-04-04
申请人： Hayley Binch , Lev T.D. Fanning , Dennis Hurley , Urvi Sheth , Alina Silina , Xiaoqing Yang , Martyn Botfield , Peter D.J. Grootenhuis , Fredrick Van Goor , Mehdi Michel Djamel Numa
发明人： Hayley Binch , Lev T.D. Fanning , Dennis Hurley , Urvi Sheth , Alina Silina , Xiaoqing Yang , Martyn Botfield , Peter D.J. Grootenhuis , Fredrick Van Goor , Mehdi Michel Djamel Numa
IPC分类号： A61K31/4709 , C07D487/08 , C07F7/10 , A61P11/06 , A61P11/00 , A61P1/10 , A61P1/18 , A61P1/16 , A61P35/00 , A61P3/10 , A61P25/28 , A61P25/16 , A61P25/14 , C12N5/071 , C07D451/02
CPC分类号： A61K31/4709 , A61K45/06 , C07D215/56 , C07D221/22 , C07D451/02 , C07D471/06 , C07D471/08 , C07D487/04 , C07D487/08 , C07F7/1804 , G01N33/5041 , G01N33/6872 , G01N2800/382
摘要： The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
摘要翻译： 本发明涉及囊性纤维化跨膜传导调节剂（“CFTR”）的调节剂，其组合物及其方法。 本发明还涉及使用CFTR的调节剂治疗疾病的方法。
-
公开(公告)号：US07846954B2
公开(公告)日：2010-12-07
申请号：US12495880
申请日：2009-07-01
申请人： Nicole Zimmermann , Peter D. J. Grootenhuis , Mehdi Michel Djamel Numa , Dean Stamos , Corey Don Anderson , Tara Whitney
发明人： Nicole Zimmermann , Peter D. J. Grootenhuis , Mehdi Michel Djamel Numa , Dean Stamos , Corey Don Anderson , Tara Whitney
IPC分类号： C07D277/00 , A01N43/78
CPC分类号： C07D417/14
摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译： 本发明涉及可用作离子通道抑制剂的杂环衍生物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
-
公开(公告)号：US20090131440A1
公开(公告)日：2009-05-21
申请号：US12269108
申请日：2008-11-12
申请人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar
发明人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar
IPC分类号： A61K31/5377 , C07D417/14 , A61K31/454 , A61P25/00
CPC分类号： C07D417/14
摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
-
公开(公告)号：US08097636B2
公开(公告)日：2012-01-17
申请号：US12269109
申请日：2008-11-12
申请人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Tara Leanne Hampton
发明人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Tara Leanne Hampton
IPC分类号： A61K31/47 , C07D217/00
CPC分类号： C07D417/14
摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
-
公开(公告)号：US20100004300A1
公开(公告)日：2010-01-07
申请号：US12495880
申请日：2009-07-01
申请人： Nicole Zimmermann , Peter D.J. Grootenhuis , Mehdi Michel Djamel Numa , Dean Stamos , Corey Don Anderson , Tara Whitney
发明人： Nicole Zimmermann , Peter D.J. Grootenhuis , Mehdi Michel Djamel Numa , Dean Stamos , Corey Don Anderson , Tara Whitney
IPC分类号： A61K31/427 , C07D277/38 , A61P25/00
CPC分类号： C07D417/14
摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译： 本发明涉及可用作离子通道抑制剂的杂环衍生物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
-
18.发明申请PYRROLIDINONE BENZENESULFONAMIDE DERIVATIVES AS MODULATORS OF ION CHANNELS FOR THE TREATMENT OF PAIN 审中-公开作为治疗疼痛的离子通道的调节剂，吡咯烷酮苯并呋喃衍生物公开(公告)号：US20120010416A1
公开(公告)日：2012-01-12
申请号：US13178877
申请日：2011-07-08
申请人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar
发明人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Aarti Sameer Kawatkar
IPC分类号： C07D417/14
CPC分类号： C07D417/14
摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译： 本发明涉及可用作离子通道抑制剂的杂环衍生物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
-
公开(公告)号：US20090124655A1
公开(公告)日：2009-05-14
申请号：US12269109
申请日：2008-11-12
申请人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Tara Leanne Hampton
发明人： Dean Stamos , Esther Martinborough , Nicole Zimmermann , Timothy Neubert , Mehdi Michel Djamel Numa , Tara Whitney , Tara Leanne Hampton
IPC分类号： A61K31/47 , C07D217/00 , A61P25/00
CPC分类号： C07D417/14
摘要： The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译： 本发明涉及可用作离子通道抑制剂的杂环衍生物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
-
公开(公告)号：US08314239B2
公开(公告)日：2012-11-20
申请号：US12605250
申请日：2009-10-23
IPC分类号： C07D215/38
CPC分类号： C07D401/14 , C07D487/08 , Y02P20/55
摘要： The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
摘要翻译： 本发明涉及囊性纤维化跨膜电导调节剂（CFTR）的调节剂，其组合物及其方法。 本发明还涉及使用CFTR的调节剂治疗疾病的方法。
-
-
-
-
-
-
-
-
-
搜索结果
21 条记录 (耗时 0.049 秒)
