公开(公告)号：US20250027151A1

公开(公告)日：2025-01-23

申请号：US18904678

申请日：2024-10-02

Applicant: Singular Genomics Systems, Inc.

Inventor： Daan Witters ,  Allen Lipson ,  Eli N. Glezer

IPC: C12Q1/6874

Abstract: Disclosed herein, inter alia, are complexes, kits, and efficient methods of sequencing two strands of a double stranded polynucleotide.

公开(公告)号：US20240368685A1

公开(公告)日：2024-11-07

申请号：US18649323

申请日：2024-04-29

Applicant: Singular Genomics Systems, Inc.

Inventor： Eli N. Glezer ,  Daan Witters

IPC: C12Q1/6874 ,  C12Q1/6853 ,  C12Q1/6876

Abstract: Disclosed herein, inter alia, are methods and compositions for amplifying and sequencing a plurality of template nucleic acids.

公开(公告)号：US20240342718A1

公开(公告)日：2024-10-17

申请号：US18629661

申请日：2024-04-08

Applicant: Singular Genomics Systems, Inc.

Inventor： Eli N. Glezer ,  Daan Witters ,  Tung Thanh Le

IPC: B01L3/00 ,  C12Q1/6806 ,  C12Q1/6834

CPC classification number: B01L3/502761 ,  C12Q1/6806 ,  C12Q1/6834 ,  B01L2200/0647 ,  B01L2300/0829

Abstract: Disclosed herein, inter alia, are compositions and methods for amplification and sequencing of nucleic acid molecules including, for example, genetic mutations.

公开(公告)号：US20240271207A1

公开(公告)日：2024-08-15

申请号：US18588765

申请日：2024-02-27

Applicant: Singular Genomics Systems, Inc.

Inventor： Daan Witters ,  Allen Lipson ,  Eli N. Glezer

IPC: C12Q1/6874

CPC classification number: C12Q1/6874

Abstract: Disclosed herein, inter alia, are complexes, kits, and efficient methods of sequencing two strands of a double stranded polynucleotide.

公开(公告)号：US20240035078A1

公开(公告)日：2024-02-01

申请号：US18357850

申请日：2023-07-24

Applicant: Singular Genomics Systems, Inc.

Inventor： Daan Witters ,  Eli N. Glezer

IPC: C12Q1/686

CPC classification number: C12Q1/686

Abstract: Disclosed herein, inter alia, are methods for increasing monoclonal nucleic acid amplification products on a solid support.

公开(公告)号：US11578320B2

公开(公告)日：2023-02-14

申请号：US17731173

申请日：2022-04-27

Applicant: SINGULAR GENOMICS SYSTEMS, INC.

Inventor： Eli N. Glezer ,  Daan Witters ,  Niek Van Wietmarschen

IPC: C12N15/10 ,  C12Q1/6806 ,  C12Q1/6874 ,  C12Q1/6844 ,  C12Q1/6837

Abstract: Disclosed herein, inter alia, are methods and compositions for sequencing a plurality of template nucleic acids.

公开(公告)号：US11236387B2

公开(公告)日：2022-02-01

申请号：US17030886

申请日：2020-09-24

Applicant: Singular Genomics Systems, Inc.

Inventor： Eli N. Glezer ,  Mohammad Vatankhah Varnosfaderani ,  Daan Witters ,  Vahid Karimkhani

IPC: C12Q1/6869

Abstract: Provided herein are methods and compositions for improved sequencing techniques using, for example, polymeric particles and/or three-dimensional structures.

公开(公告)号：US12227799B2

公开(公告)日：2025-02-18

申请号：US17542343

申请日：2021-12-03

Applicant: Singular Genomics Systems, Inc.

Inventor： Eli N. Glezer ,  Mohammad Vatankhah Varnosfaderani ,  Daan Witters ,  Vahid Karimkhani

IPC: C12Q1/6869 ,  C12Q1/6844 ,  C12Q1/6874 ,  G01N33/53 ,  G01N33/544

Abstract: Provided herein are methods and compositions for improved sequencing techniques using, for example, polymeric particles and/or three-dimensional structures.

公开(公告)号：US20240240251A1

公开(公告)日：2024-07-18

申请号：US18584749

申请日：2024-02-22

Applicant: Singular Genomics Systems, Inc

Inventor： Eli N. Glezer ,  Daan Witters ,  Tung Thanh Le

IPC: C12Q1/6874 ,  B01L3/00

CPC classification number: C12Q1/6874 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2200/16 ,  B01L2300/0829 ,  C12Q2600/16

Abstract: Disclosed herein, inter alia, are compositions and methods for efficient amplification and sequencing of nucleic acid templates.

公开(公告)号：US11913071B2

公开(公告)日：2024-02-27

申请号：US18154630

申请日：2023-01-13

Applicant: Singular Genomics Systems, Inc.

Inventor： Daan Witters ,  Eli N. Glezer ,  Allen Lipson

IPC: C12Q1/6869 ,  C12Q1/6834

CPC classification number: C12Q1/6869 ,  C12Q1/6834

Abstract: Disclosed herein, inter alia, are substrates, kits, and efficient methods of preparing and sequencing two or more regions of a double-stranded polynucleotide.