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公开(公告)号：US20100092545A1
公开(公告)日：2010-04-15
申请号：US12614928
申请日：2009-11-09
IPC分类号： B29C39/00 , A61K47/30 , A61K47/32 , A61K47/38 , A61K47/42 , A61K47/36 , A61K31/195 , A61K38/43 , A61K31/74 , A61K31/7088 , A61K35/66 , A61K39/35 , A61K39/00 , A61K8/18 , A61K8/11 , A23L1/221 , A61K31/496 , A61K31/5025 , A61K31/495 , A61K31/44 , A61K38/02 , A61K38/28 , A61K31/4164 , A61K31/341 , A61K31/426 , A61K31/352 , A61K31/137 , A61K31/4545 , A61K9/70 , A61P25/28 , A61P25/06 , A61P25/24 , A61P35/04 , A61P25/34 , A61P25/18 , A61P1/12 , A61P29/00 , A61P3/10 , A61P3/00 , A61P9/12 , A61P13/02 , A61P19/10
CPC分类号： A61K8/731 , A61K8/0216 , A61K8/86 , A61K9/006 , A61K9/7007 , A61K9/7015 , A61K2800/92 , A61Q11/00 , C08J5/18 , C08J2371/02 , F26B13/104
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. The films contain a polymer component, which includes polyethylene oxide optionally blended with hydrophilic cellulosic polymers. Desirably, the films also contain a pharmaceutical and/or cosmetic active agent with no more than a 10% variance of the active agent pharmaceutical and/or cosmetic active agent per unit area of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 膜包含聚合物组分，其包括任选地与亲水性纤维素聚合物共混的聚环氧乙烷。 期望地，膜还含有药物和/或化妆品活性剂，其每单位面积膜的活性剂药物和/或美容活性剂的变化不超过10％。
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12.发明申请THIN FILM WITH NON-SELF-AGGREGATING UNIFORM HETEROGENEITY AND DRUG DELIVERY SYSTEMS MADE THEREFROM 失效具有非自我聚集均匀异质性和药物输送系统的薄膜公开(公告)号：US20080260805A1
公开(公告)日：2008-10-23
申请号：US12102071
申请日：2008-04-14
CPC分类号： A61J3/00 , A61K9/006 , A61K9/7007 , B29C47/0021 , B29C47/8805 , B29C47/8895 , F26B13/10 , F26B13/104
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
摘要翻译： 本发明涉及含有所需水平的活性成分的薄膜产品及其制备方法。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 期望地，膜可以暴露于高于活性组分通常降解的温度，而不考虑所需活性的损失。
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公开(公告)号：US07824588B2
公开(公告)日：2010-11-02
申请号：US12102071
申请日：2008-04-14
IPC分类号： B29C39/14
CPC分类号： A61J3/00 , A61K9/006 , A61K9/7007 , B29C47/0021 , B29C47/8805 , B29C47/8895 , F26B13/10 , F26B13/104
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
摘要翻译： 本发明涉及含有所需水平的活性成分的薄膜产品及其制备方法。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 期望地，膜可以暴露于高于活性组分通常降解的温度，而不考虑所需活性的损失。
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14.发明申请THIN FILM WITH NON-SELF-AGGREGATING UNIFORM HETEROGENEITY AND DRUG DELIVERY SYSTEMS MADE THEREFROM 审中-公开具有非自我聚集均匀异质性和药物输送系统的薄膜公开(公告)号：US20080226695A1
公开(公告)日：2008-09-18
申请号：US12128950
申请日：2008-05-29
IPC分类号： A61K9/70
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/1635 , A61K9/1652 , A61K9/7015 , A61K31/192 , A61K31/422 , A61K31/435 , A61K31/4525 , A61K31/4545 , A61K31/80 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/38 , A61K47/44 , A61K47/46 , C08J5/18
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 理想地，膜在水中分解，并且可以通过受控的干燥过程或保持膜所需均匀性的其它方法形成。
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公开(公告)号：US5876506A
公开(公告)日：1999-03-02
申请号：US909517
申请日：1997-08-12
申请人： Subraman R. Cherukuri , Jose F. Zamudio-Tena , Robert K. Yang , Garry L. Myers , Andrea S. Blake , Paul M. Croushorn
发明人： Subraman R. Cherukuri , Jose F. Zamudio-Tena , Robert K. Yang , Garry L. Myers , Andrea S. Blake , Paul M. Croushorn
CPC分类号： A23G3/343 , A23G3/346 , C13B30/02 , C13B30/021 , C13B50/002 , A23G2200/06
摘要： The present invention is a new mesomorphic polycrystallite product and a process for making the same. In the present invention amorphous sugar is transformed to a mesomorphic product having polycrystallites therein by a completely anhydrous process rather than by hydrating and then dehydrating the sugar. The product of the present invention is unique in shape and size, and possesses a high degree of uniformity. The properties of the polycrystallite make it possible to replace some or all of the fat in comestibles such as frostings and fillings and to provide fondants of extraordinarily fine grain.
摘要翻译： 本发明是一种新的介晶多晶产品及其制造方法。 在本发明中，无定形糖通过完全无水的方法转化成其中具有多晶的介晶产物，而不是通过水合然后使糖脱水。 本发明的产品的形状和尺寸是独特的，并且具有高度的均匀性。 多晶的性质使得可以取代食物中的部分或全部脂肪，如结霜和馅料，并提供特别细的颗粒的软糖。
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公开(公告)号：US5874110A
公开(公告)日：1999-02-23
申请号：US898306
申请日：1997-07-22
CPC分类号： A61K9/1623 , Y10S514/951 , Y10S514/963
摘要： The present invention is a method of entrapping an additive within carbohydrate bodies. The additive is drawn into the internal structure as a fluid during transformation of the bodies from a substantially amorphous state to a crystalline state. The present invention is also a delivery system including a carbohydrate body having an internal free volume space defined by an at least partially crystalline structure at equilibrium conditions, and an additive loaded within the carbohydrate body.
摘要翻译： 本发明是在碳水化合物体内捕获添加剂的方法。 在将体从基本无定形状态转变为结晶状态时，添加剂作为流体被吸入内部结构。 本发明还是一种递送系统，其包括在平衡条件下具有由至少部分结晶结构限定的内部自由体积空间的碳水化合物体和在碳水化合物体内加载的添加剂。
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17.发明授权Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom 有权具有非自聚集均匀异质性的薄膜和由其制备的药物递送系统公开(公告)号：US07425292B2
公开(公告)日：2008-09-16
申请号：US10074272
申请日：2002-02-14
CPC分类号： A61K9/7007 , A61K9/0056 , A61K9/006 , A61K9/1635 , A61K9/1652 , A61K9/7015 , A61K31/192 , A61K31/422 , A61K31/435 , A61K31/4525 , A61K31/4545 , A61K31/80 , A61K47/02 , A61K47/10 , A61K47/22 , A61K47/32 , A61K47/38 , A61K47/44 , A61K47/46 , C08J5/18
摘要： The invention relates to the film products and methods of their preparation that demonstrate a non-self-aggregating uniform heterogeneity. Desirably the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film.
摘要翻译： 本发明涉及其制备的薄膜产品及其制备方法，其表现出非自聚集均匀的异质性。 理想地，膜在水中分解，并且可以通过受控的干燥过程或保持膜所需均匀性的其它方法形成。
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公开(公告)号：US5683720A
公开(公告)日：1997-11-04
申请号：US330412
申请日：1994-10-28
申请人： Garry L. Myers , Robert K. Yang , Mark R. Herman
发明人： Garry L. Myers , Robert K. Yang , Mark R. Herman
IPC分类号： A61J3/02 , A61J1/00 , A61J7/00 , A61K9/00 , A61K9/16 , A61K9/20 , A61K9/50 , B01J2/00 , B01J2/02 , A61K9/14
CPC分类号： A61J7/0015 , A61J1/00 , A61K9/1688 , A61K9/1694 , A61K9/2081 , A61K9/2095 , A61K9/5026 , B01J2/00 , B01J2/02
摘要： The present invention is a method of making discrete particles by subjecting an organic feedstock to liquiflash conditions whereby the feedstock is transformed instantaneously from solid to liquiform to solid. Liquiform is a transient condition wherein the feedstock has substantially unimpeded internal flow. Shear force is imparted to the liquiform feedstock in an amount sufficient to separate tiny masses of feedstock. The tiny masses solidify as discretized particles. The present invention also includes unique products resulting from the process, e.g., a monodispersed microsphere product and coated particles prepared therefrom.
摘要翻译： 本发明是通过使有机原料经历液化条件来制备离散颗粒的方法，由此原料从固体瞬间转变成液态至固体。 液体是一种瞬态条件，其中原料具有基本上无阻碍的内部流动。 剪切力被赋予液体原料，其量足以分离出微量的原料。 微小的团块固化为离散粒子。 本发明还包括由该方法产生的独特产物，例如单分散的微球产物和由其制备的包衣颗粒。
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19.发明申请THIN FILM WITH NON-SELF-AGGREGATING UNIFORM HETEROGENEITY AND DRUG DELIVERY SYSTEMS MADE THEREFROM 审中-公开具有非自我聚集均匀异质性和药物输送系统的薄膜公开(公告)号：US20110182969A1
公开(公告)日：2011-07-28
申请号：US13052655
申请日：2011-03-21
CPC分类号： A61J3/00 , A61K9/006 , A61K9/7007 , B29C48/08 , B29C48/91 , B29C48/919 , F26B13/10 , F26B13/104
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
摘要翻译： 本发明涉及含有所需水平的活性成分的薄膜产品及其制备方法。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 期望地，膜可以暴露于高于活性组分通常降解的温度，而不考虑所需活性的损失。
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公开(公告)号：US07357891B2
公开(公告)日：2008-04-15
申请号：US10768809
申请日：2004-01-30
IPC分类号： B29C47/88
CPC分类号： A61J3/00 , A61K9/006 , A61K9/7007 , B29C47/0021 , B29C47/8805 , B29C47/8895 , F26B13/10 , F26B13/104
摘要： The invention relates to film products containing desired levels of active components and methods of their preparation. Desirably, the films disintegrate in water and may be formed by a controlled drying process, or other process that maintains the required uniformity of the film. Desirably, the films may be exposed to temperatures above that at which the active components typically degrade without concern for loss of the desired activity.
摘要翻译： 本发明涉及含有所需水平的活性成分的薄膜产品及其制备方法。 期望地，膜在水中分解并且可以通过受控的干燥过程或保持膜所需的均匀性的其它方法形成。 期望地，膜可以暴露于高于活性组分通常降解的温度，而不考虑所需活性的损失。
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