公开(公告)号：US06562034B2

公开(公告)日：2003-05-13

申请号：US10046637

申请日：2002-01-14

Applicant: Stuart D Edwards ,  John Gaiser ,  David S Utley ,  Scott West ,  Jay Qin

Inventor： Stuart D Edwards ,  John Gaiser ,  David S Utley ,  Scott West ,  Jay Qin

IPC: A61B1818

CPC classification number: A61B18/1485 ,  A61B18/1477 ,  A61B18/1492 ,  A61B2017/00867 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00553 ,  A61B2018/00738 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2090/036 ,  C08L2201/12

Abstract: Improved electrode assemblies for treating a tissue region at or near a sphincter comprise a support structure and an electrode carried by the support structure for advancement in a path to penetrate the tissue region. In one arrangement, the electrode has a non-cylindrical cross section selected to resist deflection when advanced to penetrate the tissue region. In another arrangement, the electrode includes a tissue stop to resist tissue penetration beyond a selected depth. In another arrangement, the electrode includes a proximal portion formed from a first material and a distal tissue penetrating portion formed of a second material different than the first material. The first material can comprise, e.g., stainless steel, and the second material can comprise, e.g., nickel titanium.

公开(公告)号：US06423058B1

公开(公告)日：2002-07-23

申请号：US09304770

申请日：1999-05-04

Applicant: Stuart D Edwards ,  John Gaiser ,  David S Utley ,  Scott West ,  Jay Qin

Inventor： Stuart D Edwards ,  John Gaiser ,  David S Utley ,  Scott West ,  Jay Qin

IPC: A61B1818

CPC classification number: A61B18/1206 ,  A61B18/12 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007

Abstract: Assemblies for treating a tissue region at or near a sphincter have a support structure with a distal end and an electrode carried by the support structure for contact with the tissue region. A lumen in the support structure accommodates passage of a body through the support structure and beyond the distal end of the support structure. The body can comprise a guide wire to guide deployment of the support structure, or an endoscope to permit visualization of the support structure from beyond the distal end of the support structure.

Abstract translation: 用于治疗括约肌处或附近的组织区域的组件具有支撑结构，其具有远端和由支撑结构承载的用于与组织区域接触的电极。 支撑结构中的内腔容纳主体通过支撑结构并超出支撑结构的远端的通道。 主体可以包括引导线以引导支撑结构的展开，或内窥镜，以允许从支撑结构的远端超出支撑结构的可视化。

公开(公告)号：US07125407B2

公开(公告)日：2006-10-24

申请号：US10728684

申请日：2003-12-05

Applicant: Stuart D Edwards ,  John W. Gaiser ,  David S. Utley ,  Jay J. Qin

Inventor： Stuart D Edwards ,  John W. Gaiser ,  David S. Utley ,  Jay J. Qin

IPC: A61B18/18

CPC classification number: A61B18/1477 ,  A61B17/32 ,  A61B18/1206 ,  A61B18/148 ,  A61B18/1485 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/1815 ,  A61B2017/00084 ,  A61B2017/00106 ,  A61B2017/003 ,  A61B2017/22061 ,  A61B2017/4216 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00029 ,  A61B2018/00065 ,  A61B2018/00077 ,  A61B2018/00083 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00494 ,  A61B2018/00553 ,  A61B2018/00577 ,  A61B2018/00654 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00755 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00827 ,  A61B2018/00869 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/00892 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00982 ,  A61B2018/0262 ,  A61B2018/046 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1273 ,  A61B2018/1425 ,  A61B2018/1467 ,  A61B2018/1472 ,  A61B2018/183 ,  A61B2090/3614 ,  A61B2090/3782 ,  A61B2218/002 ,  A61M3/0279 ,  A61M16/0438 ,  A61M16/0481 ,  A61M25/1002 ,  A61M2025/1052 ,  A61M2025/1086 ,  A61N1/056 ,  A61N1/06 ,  A61N1/08 ,  A61N1/40

Abstract: A sphincter treatment apparatus includes an elongated member having at least one lumen including an inflation lumen and a basket assembly with first and second arms. The basket assembly is coupled to the elongated member and has deployed and non-deployed configurations. An inflatable member is coupled to the elongated member and positioned in an interior of the basket assembly. The inflatable member has deployed and non-deployed states and is coupled to the inflation lumen. In the deployed state, the inflatable member expands the basket assembly to its deployed configuration. A first energy delivery device is positionable in the first arm and advanceable from the first arm to a selected treatment site. A second energy delivery device is positionable in the second arm and advanceable from the second arm to a selected treatment site.

Abstract translation: 括约肌治疗装置包括细长构件，其具有包括充气腔的至少一个内腔和具有第一和第二臂的篮组件。 筐组件联接到细长构件并且具有展开和非展开构造。 可膨胀构件联接到细长构件并且定位在篮组件的内部。 充气构件具有展开状态和非展开状态，并且连接到膨胀腔。 在展开状态下，可膨胀构件将篮组件膨胀到其展开构型。 第一能量输送装置可定位在第一臂中并且可从第一臂推进到选定的处理部位。 第二能量输送装置可定位在第二臂中并且可从第二臂推进到选定的治疗部位。

公开(公告)号：US06749607B2

公开(公告)日：2004-06-15

申请号：US09971085

申请日：2001-10-04

Applicant: Stuart D Edwards ,  David S Utley

Inventor： Stuart D Edwards ,  David S Utley

IPC: A61B1818

CPC classification number: A61B18/1477 ,  A61B5/4233 ,  A61B18/0218 ,  A61B18/1492 ,  A61B2017/3445 ,  A61B2017/345 ,  A61B2018/00267 ,  A61B2018/00488 ,  A61B2018/00553 ,  A61B2018/00589 ,  A61B2018/00648 ,  A61B2018/00702 ,  A61B2018/00821 ,  A61B2018/00827 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/00994 ,  A61B2018/0262 ,  A61B2018/0293 ,  A61B2018/046 ,  A61B2018/1861 ,  A61B2018/1869

Abstract: A sphincter treatment apparatus has an introducer means including a distal portion means. An expandable device means includes a plurality of arm means. Each arm means of the plurality has a distal section means and a proximal section means. Each of distal sections means of the arm means are coupled and each of the proximal sections means of the arm means are coupled to the introducer means distal portion means. The expandable device means is configured to at least partially dilate a sphincter in a deployed state. An energy delivery device means is introduceable from the introducer means into a selected site of the sphincter. The energy delivery device means is configured to deliver sufficient energy to reduce a frequency of relaxation of the sphincter.

Abstract translation: 括约肌治疗装置具有包括远端部分装置的导引装置。 可扩张装置包括多个臂装置。 多个臂的每个臂装置具有远端部分装置和近端部分装置。 臂装置的每个远端部分装置联接，并且臂装置的每个近端部分装置联接到导引装置远端部分装置。 可扩张装置装置构造成在展开状态下至少部分地扩张括约肌。 能量输送装置装置可从导引器装置引入括约肌的选定部位。 能量递送装置装置被配置为递送足够的能量以减少括约肌的松弛频率。

公开(公告)号：US06589238B2

公开(公告)日：2003-07-08

申请号：US10084590

申请日：2002-02-27

Applicant: Stuart D Edwards ,  David S Utley

Inventor： Stuart D Edwards ,  David S Utley

IPC: A61B1818

CPC classification number: A61B18/1492 ,  A61B2018/00553

Abstract: An apparatus includes a first expandable member that is expandable by an expansion medium. The first expandable member includes an exterior and a plurality of apertures. The expansion medium is released from the first expandable member when a sufficient pressure is applied to the expansion medium housed in an interior of the first expandable member. A second expandable member is positioned at least partially adjacent to the first expandable member. The second expandable member is configured to receive at least a portion of the expansion medium from the interior of the first expandable member. An electromagnetic energy delivery device is coupled to one of the first or second expandable members and is configured to be coupled to a power source. The first and second expandable members are sized to be expanded sufficiently to open a sphincter.

Abstract translation: 一种装置包括可由膨胀介质膨胀的第一可膨胀构件。 第一可扩展构件包括外部和多个孔。 当向容纳在第一可扩展构件的内部的膨胀介质施加足够的压力时，膨胀介质从第一可膨胀构件释放。 第二可膨胀构件被定位成至少部分地邻近第一可膨胀构件。 第二可膨胀构件构造成从第一可膨胀构件的内部接收膨胀介质的至少一部分。 电磁能量传递装置耦合到第一或第二可扩展构件中的一个，并且被配置为联接到电源。 第一和第二可扩张构件的尺寸设计成足够扩张以打开括约肌。

公开(公告)号：US06254598B1

公开(公告)日：2001-07-03

申请号：US09235060

申请日：1999-01-20

Applicant: Stuart D Edwards ,  John W. Gaiser ,  David S. Utley ,  Jay J. Qin

Inventor： Stuart D Edwards ,  John W. Gaiser ,  David S. Utley ,  Jay J. Qin

IPC: A61B1818

CPC classification number: A61B18/1477 ,  A61B17/32 ,  A61B18/1206 ,  A61B18/148 ,  A61B18/1485 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/1815 ,  A61B2017/00084 ,  A61B2017/00106 ,  A61B2017/003 ,  A61B2017/22061 ,  A61B2017/4216 ,  A61B2018/00011 ,  A61B2018/00023 ,  A61B2018/00029 ,  A61B2018/00065 ,  A61B2018/00077 ,  A61B2018/00083 ,  A61B2018/00113 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00494 ,  A61B2018/00553 ,  A61B2018/00577 ,  A61B2018/00654 ,  A61B2018/00666 ,  A61B2018/00678 ,  A61B2018/00702 ,  A61B2018/00708 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00755 ,  A61B2018/00761 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00821 ,  A61B2018/00827 ,  A61B2018/00869 ,  A61B2018/00875 ,  A61B2018/00886 ,  A61B2018/00892 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/00982 ,  A61B2018/0262 ,  A61B2018/046 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1273 ,  A61B2018/1425 ,  A61B2018/1467 ,  A61B2018/1472 ,  A61B2018/183 ,  A61B2090/3614 ,  A61B2090/3782 ,  A61B2218/002 ,  A61M3/0279 ,  A61M16/0438 ,  A61M16/0481 ,  A61M25/1002 ,  A61M2025/1052 ,  A61M2025/1086 ,  A61N1/056 ,  A61N1/06 ,  A61N1/08 ,  A61N1/40

Abstract: A sphincter treatment apparatus includes an elongated member having at least one lumen including an inflation lumen and a basket assembly with first and second arms. The basket assembly is coupled to the elongated member and has deployed and non-deployed configurations. An inflatable member is coupled to the elongated member and positioned in an interior of the basket assembly. The inflatable member has deployed and non-deployed states and is coupled to the inflation lumen. In the deployed state, the inflatable member expands the basket assembly to its deployed configuration. A first energy delivery device is positionable in the first arm and advanceable from the first arm to a selected treatment site. A second energy delivery device is positionable in the second arm and advanceable from the second arm to a selected treatment site.

Abstract translation: 括约肌治疗装置包括细长构件，其具有包括充气腔的至少一个内腔和具有第一和第二臂的篮组件。 筐组件联接到细长构件并且具有展开和非展开构造。 可膨胀构件联接到细长构件并且定位在篮组件的内部。 充气构件具有展开状态和非展开状态，并且连接到膨胀腔。 在展开状态下，可膨胀构件将篮组件膨胀到其展开构型。 第一能量输送装置可定位在第一臂中并且可从第一臂推进到选定的处理部位。 第二能量输送装置可定位在第二臂中并且可从第二臂推进到选定的治疗部位。

公开(公告)号：US08790339B2

公开(公告)日：2014-07-29

申请号：US13443503

申请日：2012-04-10

Applicant: Stuart D Edwards ,  David S Utley ,  Ronald G Lax

Inventor： Stuart D Edwards ,  David S Utley ,  Ronald G Lax

IPC: A61B18/14

CPC classification number: A61B5/04884 ,  A61B18/1477 ,  A61B18/1485 ,  A61B90/39 ,  A61B2018/00553 ,  A61B2018/00738 ,  A61B2018/046 ,  A61B2090/3925 ,  A61B2560/0242

Abstract: An apparatus to treat a sphincter has a support member. A sphincter electropotential mapping device includes a mapping electrode. The sphincter electropotential mapping device is coupled to the support member and configured to detect aberrant myoelectric activity of the sphincter.

Abstract translation: 治疗括约肌的装置具有支撑构件。 括约肌电位映射装置包括映射电极。 括约肌电位映射设备耦合到支撑构件并且被配置为检测括约肌的异常肌电活动。

公开(公告)号：US07122031B2

公开(公告)日：2006-10-17

申请号：US10024747

申请日：2001-12-19

Applicant: Stuart D Edwards ,  John W. Gaiser ,  David S Utley ,  Scott H. West ,  Jay Qin

Inventor： Stuart D Edwards ,  John W. Gaiser ,  David S Utley ,  Scott H. West ,  Jay Qin

IPC: A61B18/18

CPC classification number: A61B18/1233 ,  A61B18/12 ,  A61B18/1206 ,  A61B18/14 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00035 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00488 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007 ,  Y10S128/922

Abstract: Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.

公开(公告)号：US06846312B2

公开(公告)日：2005-01-25

申请号：US10230655

申请日：2002-08-29

Applicant: Stuart D Edwards ,  David S Utley

Inventor： Stuart D Edwards ,  David S Utley

IPC: A61B17/22 ,  A61B18/00 ,  A61B18/12 ,  A61B18/14 ,  A61B18/18

CPC classification number: A61B18/1492 ,  A61B18/1206 ,  A61B18/1477 ,  A61B2017/003 ,  A61B2017/22061 ,  A61B2018/00011 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/0016 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00875 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1467 ,  A61B2018/1472 ,  A61B2090/3782

Abstract: An apparatus to treat a sphincter includes an energy delivery device support member. An energy delivery device is coupled to the energy delivery support member. The energy delivery device has a configuration that controllably produces lesions of a sufficient size and number in the sphincter to create a selectable tightening of the sphincter.

Abstract translation: 治疗括约肌的装置包括能量输送装置支撑构件。 能量输送装置联接到能量输送支撑构件。 能量输送装置具有可控制地产生足够尺寸和数量的括约肌中的损伤以构成括约肌的可选择紧固的构造。

公开(公告)号：US08906010B2

公开(公告)日：2014-12-09

申请号：US12001091

申请日：2007-12-10

Applicant: Stuart D Edwards ,  John W. Gaiser ,  David S Utley ,  Scott H. West ,  Jay Qin ,  Peter H Muller

Inventor： Stuart D Edwards ,  John W. Gaiser ,  David S Utley ,  Scott H. West ,  Jay Qin ,  Peter H Muller

IPC: A61B18/14 ,  A61B18/12 ,  A61B19/00 ,  A61B18/00 ,  A61B18/04

CPC classification number: A61B18/12 ,  A61B18/1206 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007

Abstract: Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.

Abstract translation: 系统和方法部署与组织区域接触的电极结构。 电极结构在电极结构上的已知位置处携带传感器以监测操作状态。 系统和方法提供了一种接口，其产生电极结构的理想化图像和指示图像，以在对应于电极结构上的传感器的位置的理想化图像上的空间位置中表示监视的操作条件。 界面显示包含理想图像和指示图像的视图。 当视觉图像显示在显示屏上时，系统和方法使电极结构施加能量来加热组织区域。