公开(公告)号：US20070093809A1

公开(公告)日：2007-04-26

申请号：US11638952

申请日：2006-12-14

Applicant: Stuart Edwards ,  David Utley

Inventor： Stuart Edwards ,  David Utley

IPC: A61B18/14

CPC classification number: A61B18/1477 ,  A61B5/4233 ,  A61B18/0218 ,  A61B18/1492 ,  A61B2017/3445 ,  A61B2017/345 ,  A61B2018/00267 ,  A61B2018/00488 ,  A61B2018/00553 ,  A61B2018/00589 ,  A61B2018/00648 ,  A61B2018/00702 ,  A61B2018/00821 ,  A61B2018/00827 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/00994 ,  A61B2018/0262 ,  A61B2018/0293 ,  A61B2018/046 ,  A61B2018/1861 ,  A61B2018/1869

Abstract: A sphincter treatment apparatus has an introducer means including a distal portion means. An expandable device means includes a plurality of arm means. Each arm means of the plurality has a distal section means and a proximal section means. Each of distal sections means of the arm means are coupled and each of the proximal sections means of the arm means are coupled to the introducer means distal portion means. The expandable device means is configured to at least partially dilate a sphincter in a deployed state. An energy delivery device means is introduceable from the introducer means into a selected site of the sphincter. The energy delivery device means is configured to deliver sufficient energy to reduce a frequency of relaxation of the sphincter.

Abstract translation: 括约肌治疗装置具有包括远端部分装置的导引装置。 可扩张装置包括多个臂装置。 多个臂的每个臂装置具有远端部分装置和近端部分装置。 臂装置的每个远端部分装置联接，并且臂装置的每个近端部分装置联接到导引装置远端部分装置。 可扩张装置装置构造成在展开状态下至少部分地扩张括约肌。 能量输送装置装置可从导引器装置引入括约肌的选定部位。 能量递送装置装置被配置为递送足够的能量以减少括约肌的松弛频率。

公开(公告)号：US20070032788A1

公开(公告)日：2007-02-08

申请号：US11580543

申请日：2006-10-13

Applicant: Stuart Edwards ,  John Gaiser ,  David Utley ,  Jay Qin

Inventor： Stuart Edwards ,  John Gaiser ,  David Utley ,  Jay Qin

IPC: A61B18/14

Abstract: An apparatus treats tissue at or near a sphincter. The apparatus has an elongated member having at least one lumen including an inflation lumen, and a basket assembly including a first and a second arm. An inflatable member is coupled to the inflation lumen and has a deployed and a non-deployed state. In the deployed state, the inflatable member expands the basket assembly into contact with tissue. At least one of the first and second arms of the basket assembly has a fluid lumen having an aperture for conveying a fluid from the basket assembly. A source of fluid is coupled to the fluid lumen for conveyance of fluid through the aperture. The fluid can be, e.g., an electrolytic solution, and/or an anti-infection agent, and/or an echogenic media, and/or a steroid, and/or an anesthetic, and/or a medicament, and/or a tissue cooling agent. The source can be a drug delivery device.

Abstract translation: 装置处理括约肌处或附近的组织。 该装置具有细长构件，其具有包括充气腔的至少一个腔，以及包括第一臂和第二臂的篮组件。 可膨胀构件联接到膨胀腔并具有展开和非展开状态。 在展开状态下，可膨胀构件将篮组件膨胀成与组织接触。 篮组件的第一和第二臂中的至少一个具有流体腔，其具有用于从篮组件输送流体的孔。 流体源耦合到流体腔，用于输送流体通过该孔。 流体可以是例如电解溶液和/或抗感染剂和/或回声介质，和/或类固醇，和/或麻醉剂，和/或药物，和/或组织 冷却剂。 来源可以是药物递送装置。

公开(公告)号：US20060282071A1

公开(公告)日：2006-12-14

申请号：US11420722

申请日：2006-05-26

Applicant: David Utley ,  John Gaiser ,  Stuart Edwards ,  Scott West ,  Jay Qin

Inventor： David Utley ,  John Gaiser ,  Stuart Edwards ,  Scott West ,  Jay Qin

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B18/12 ,  A61B18/1206 ,  A61B18/1477 ,  A61B18/1485 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007

Abstract: Methods of ablating mucosal tissue in an alimentary canal are provided. The methods can include the steps of (i) providing an ablation device comprising a tissue ablation source; (ii) positioning at least a portion of the ablation device at a mucosal tissue surface of the alimentary canal; (iii) delivering a sufficient amount of the source for tissue ablation to the mucosal tissue surface to create a lesion in the mucosal tissue. In one implementation the methods include a step of providing a radiofrequency (RF) energy delivery device.

Abstract translation: 提供消化道中消融粘膜组织的方法。 所述方法可以包括以下步骤：（i）提供包括组织消融源的消融装置; （ii）将消融装置的至少一部分定位在消化道的粘膜组织表面; （iii）将足够量的用于组织消融的来源输送到粘膜组织表面以在粘膜组织中产生损伤。 在一个实现中，所述方法包括提供射频（RF）能量传递装置的步骤。

公开(公告)号：US20060259030A1

公开(公告)日：2006-11-16

申请号：US11420719

申请日：2006-05-26

Applicant: David Utley ,  John Gaiser ,  Stuart Edwards ,  Scott West ,  Jay Qin

Inventor： David Utley ,  John Gaiser ,  Stuart Edwards ,  Scott West ,  Jay Qin

IPC: A61B18/18

CPC classification number: A61B18/1492 ,  A61B18/12 ,  A61B18/1206 ,  A61B18/1477 ,  A61B18/1485 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007

Abstract: Methods of accessing and ablating abnormal epithelium tissue in an alimentary canal are provided. The methods can include steps of (i) inserting a vacuum source comprising one or more suction ports into an alimentary canal; (ii) inserting an operative element comprising a conduit for a tissue ablation source into the alimentary canal; (iii) positioning the vacuum source and the operative element proximate a portion of the alimentary canal having a site of abnormal tissue to be ablated; (iv) applying a vacuum to at least one of each suction port to draw the tissue against the operative element; and (v) applying the tissue ablation source to the tissue through the conduit to effect tissue ablation.

Abstract translation: 提供了在消化道中获取和消融异常上皮组织的方法。 所述方法可以包括以下步骤：（i）将包括一个或多个吸入口的真空源插入消化道; （ii）将包括用于组织消融源的导管的操作元件插入消化道中; （iii）将真空源和操作元件定位在具有要消融的异常组织部位的消化道的一部分附近; （iv）向每个抽吸口中的至少一个施加真空以将组织拉向操作元件; 和（v）通过导管将组织消融源施加到组织以实现组织消融。

公开(公告)号：US20060259028A1

公开(公告)日：2006-11-16

申请号：US11420712

申请日：2006-05-26

Applicant: David Utley ,  John Gaiser ,  Stuart Edwards ,  Scott West ,  Jay Qin

Inventor： David Utley ,  John Gaiser ,  Stuart Edwards ,  Scott West ,  Jay Qin

IPC: A61B18/18

CPC classification number: A61B18/1492 ,  A61B18/12 ,  A61B18/1206 ,  A61B18/1477 ,  A61B18/1485 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007

Abstract: Systems for treating a mucosal surface of an alimentary canal tissue region are provided. The systems can include an elongate support structure, an expandable member positionable at a distal portion of the support structure and one or more radio frequency (RF) ablation electrodes carried by the expandable member. The elongate support structure and the expandable member can be adapted to place the one or more electrodes in contact with a mucosal surface of an alimentary canal tissue region. The system can further include an RF energy source connected to the one or more electrodes.

Abstract translation: 提供了用于治疗消化道组织区域的粘膜表面的系统。 该系统可以包括细长的支撑结构，可定位在支撑结构的远端部分处的可扩张构件以及由可扩张构件承载的一个或多个射频（RF）消融电极。 细长支撑结构和可扩张构件可适于将一个或多个电极与消化道组织区域的粘膜表面接触。 该系统还可以包括连接到一个或多个电极的RF能量源。

公开(公告)号：US20060041256A1

公开(公告)日：2006-02-23

申请号：US11254951

申请日：2005-10-20

Applicant: Stuart Edwards ,  David Utley

Inventor： Stuart Edwards ,  David Utley

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B2018/00553

Abstract: A method of forming a composite lesion pattern in a tissue region at or near a sphincter comprising providing a catheter having a plurality of energy delivery devices coupled to the catheter. The catheter is introduced at least partially into the sphincter. Energy is delivered from the energy delivery devices to produce the composite lesion pattern. The composite lesion pattern comprises a radial distribution of lesions about the tissue region and a longitudinal distribution of lesions along the tissue region.

Abstract translation: 在括约肌处或附近在组织区域中形成复合损伤图案的方法，包括提供具有耦合到导管的多个能量输送装置的导管。 将导管至少部分地引入括约肌。 能量从能量输送装置输送以产生复合损伤模式。 复合损伤图案包括围绕组织区域的损伤的径向分布和沿着组织区域的损伤的纵向分布。

公开(公告)号：US20050245926A1

公开(公告)日：2005-11-03

申请号：US11175471

申请日：2005-07-06

Applicant: Stuart Edwards ,  David Utley ,  Ronald Lax ,  Theodore Kucklick ,  Peter Muller

Inventor： Stuart Edwards ,  David Utley ,  Ronald Lax ,  Theodore Kucklick ,  Peter Muller

IPC: A61B18/00 ,  A61B18/14

CPC classification number: A61B18/14 ,  A61B17/32 ,  A61B18/1477 ,  A61B18/1492 ,  A61B18/1815 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00494 ,  A61B2018/00553 ,  A61B2018/00577 ,  A61B2018/00702 ,  A61B2018/00726 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00916 ,  A61B2018/124 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1472 ,  A61B2018/183 ,  A61B2090/3614 ,  A61B2090/3782

Abstract: A sphincter treatment apparatus includes an energy delivery device introduction member including a proximal end with a first radius of curvature and a distal end with a second radius of curvature. The introduction member is configured to be introduced into the sphincter in a non-deployed state and to be expanded to a deployed state to at least partially expand the sphincter or an adjoining structure. An energy delivery device is coupled to the introduction member. A retainer member is coupled to the energy delivery device introduction member and configured to controllably position the introduction member in an orifice of the sphincter.

Abstract translation: 括约肌治疗装置包括能量输送装置导入构件，其包括具有第一曲率半径的近端和具有第二曲率半径的远端。 引入构件被配置为以非展开状态引入括约肌并且被扩展到展开状态以至少部分地扩展括约肌或相邻结构。 能量输送装置联接到引入构件。 保持器构件联接到能量输送装置引入构件并构造成将引导构件可控地定位在括约肌的孔中。

公开(公告)号：US06325798B1

公开(公告)日：2001-12-04

申请号：US09304743

申请日：1999-05-04

Applicant: Stuart Edwards ,  John Gaiser ,  David Utley ,  Scott West ,  Jay Chin ,  Ronald Lax

Inventor： Stuart Edwards ,  John Gaiser ,  David Utley ,  Scott West ,  Jay Chin ,  Ronald Lax

IPC: A61B1818

CPC classification number: A61B18/1206 ,  A61B18/12 ,  A61B18/1477 ,  A61B18/1485 ,  A61B18/1492 ,  A61B2017/22067 ,  A61B2017/308 ,  A61B2017/3488 ,  A61B2018/00011 ,  A61B2018/00029 ,  A61B2018/00077 ,  A61B2018/00148 ,  A61B2018/00214 ,  A61B2018/00232 ,  A61B2018/00261 ,  A61B2018/00267 ,  A61B2018/00273 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00553 ,  A61B2018/00654 ,  A61B2018/0066 ,  A61B2018/00702 ,  A61B2018/00755 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/00815 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/046 ,  A61B2018/1425 ,  A61B2018/1475 ,  A61B2090/036 ,  A61B2090/3782 ,  A61B2218/002 ,  A61B2218/007

Abstract: Systems and methods treat a tissue region at or near a sphincter by deploying a carrier, which carries an electrode that can be advanced to penetrate tissue. Negative pressure is applied through a suction port on the carrier near the electrode, to draw tissue in the tissue region inward against the carrier. The systems and methods advance the electrode to penetrate tissue drawn against the carrier. The vacuum anchors the surrounding tissue and mediates against the “tenting” of tissue during electrode penetration. Without tenting, the electrode penetrates mucosal tissue fully, to obtain a desired depth of penetration.

Abstract translation: 系统和方法通过展开携带可以被推进穿透组织的电极的载体来处理括约肌处或附近的组织区域。 通过电极附近的载体上的吸入口施加负压，将组织区域中的组织向内抵靠载体。 这些系统和方法使电极移动以穿透抵靠载体的组织。 真空锚定周围的组织，并在电极穿透期间抵抗组织的“隆起”进行介导。 没有隆起，电极完全渗透粘膜组织，以获得所需的穿透深度。

公开(公告)号：US20060047331A1

公开(公告)日：2006-03-02

申请号：US11058845

申请日：2005-02-15

Applicant: Ronald Lax ,  Gary Fanton ,  Stuart Edwards

Inventor： Ronald Lax ,  Gary Fanton ,  Stuart Edwards

IPC: A61F7/00 ,  A61F7/12

CPC classification number: A61B18/148 ,  A61B2018/00023 ,  A61B2018/00083 ,  A61B2018/00452 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/143 ,  A61B2018/1472 ,  A61B2018/1497 ,  A61B2018/1861 ,  A61N1/40

Abstract: An apparatus and method are provided for control contraction of tissue that includes collagen fibers. The apparatus includes a handpiece, and an electrode with an electrode proximal end associated with the handpiece. A distal end of the electrode has a geometry that delivers a controlled amount of energy to the tissue for a desired contraction of the collagen fibers. This is achieved while dissociation and breakdown of the collagen fibers is minimized. The handpiece, with electrode, is adapted to be introduced through an operating cannula in percutaneous applications. Additionally, an operating cannula may be included in the apparatus and be attached to the handpiece. The apparatus and method provides for a desired level of contraction of collagen soft tissue without dissociation or breakdown of collagen fibers.

公开(公告)号：US20050189271A1

公开(公告)日：2005-09-01

申请号：US11114602

申请日：2005-04-26

Applicant: Claudio Cerutti ,  Artemio Affaticati ,  Stuart Edwards

Inventor： Claudio Cerutti ,  Artemio Affaticati ,  Stuart Edwards

IPC: B65G47/46 ,  B07C5/36 ,  B65G1/137 ,  B65G17/34 ,  B65G43/08 ,  B65G47/52 ,  B65G47/10

CPC classification number: B07C3/02 ,  B07C5/36 ,  B65G17/345 ,  B65G43/08 ,  B65G47/52 ,  B65G2201/02 ,  B65G2201/0288 ,  Y10S209/912

Abstract: An article sortation system includes a plurality of transport units which are movable along a conveying path between induction stations and discharge stations along each side of the conveying path. Each transport unit has side by side loading and support capability and is operable to receive packages from induction stations and discharge the packages at an appropriate discharge station. The system includes a control which determines the destination of articles and resolves blocking conditions between articles at the induction stations or at the transport units. The system may include a reinduction station for receiving an article from a transport unit and reinducting the article onto a transport unit, in order to resolve a blocking condition between a pair of articles on the respective transport unit.