Fractalkine binding polynucleotides and methods of use
    11.
    发明授权
    Fractalkine binding polynucleotides and methods of use 有权
    Fractalkine结合多核苷酸及其使用方法

    公开(公告)号:US08883989B2

    公开(公告)日:2014-11-11

    申请号:US13655155

    申请日:2012-10-18

    IPC分类号: C12N15/11 C12N15/115

    摘要: Provided herein are polynucleotides that bind to fractalkine. In one embodiment, a polynucleotide includes the polynucleotide sequence SEQ ID NO:1 or a sequence having at least 80% identity to SEQ ID NO:1. Also provided herein are structures that include such a polynucleotide present on its surface, including 2-dimentional and 3-dimentional structures. Also provided are compositions that include such a polynucleotide, and methods for using the polynucleotides.

    摘要翻译: 本文提供了结合分子链的多核苷酸。 在一个实施方案中,多核苷酸包括多核苷酸序列SEQ ID NO:1或与SEQ ID NO:1具有至少80%同一性的序列。 本文还提供包括其表面上存在的这种多核苷酸的结构,包括二维和三维结构。 还提供了包括这种多核苷酸的组合物,以及使用多核苷酸的方法。

    POLYMERIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME
    12.
    发明申请
    POLYMERIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME 审中-公开
    聚合电致发光器件及其制备方法

    公开(公告)号:US20140326986A1

    公开(公告)日:2014-11-06

    申请号:US14361005

    申请日:2011-11-28

    IPC分类号: H01L51/50 H01L51/00 H01L51/56

    摘要: Disclosed are a polymeric electroluminescent device and a method for preparing the same. The polymeric electroluminescent device includes an anode (20), a hole injecting layer (30), a hole transportation layer (40), a light-emitting layer (50), a hole barrier layer (60), an electron transportation layer (70), an electron injecting layer (80) and a cathode (90) laminated in succession, and the material for the hole barrier layer (60) is zinc oxide, magnesium oxide, zinc sulphide or cadmium sulphide. In the polymeric electroluminescent device, zinc oxide, magnesium oxide, zinc sulphide or cadmium sulphide has a large particle size, and can scatter the light to improve extraction efficiency; at the same time, zinc oxide, magnesium oxide, zinc sulphide or cadmium sulphide has a high work function, which can excellently prevent transition of the holes and increase the recombination possibility of excitons, thereby improving the light-emitting efficiency of the polymeric electroluminescent device.

    摘要翻译: 公开了一种聚合物电致发光器件及其制备方法。 聚合物电致发光器件包括阳极(20),空穴注入层(30),空穴传输层(40),发光层(50),空穴阻挡层(60),电子传输层 ),电子注入层(80)和阴极(90),空穴阻挡层(60)的材料是氧化锌,氧化镁,硫化锌或硫化镉。 在聚合物电致发光器件中,氧化锌,氧化镁,硫化锌或硫化镉具有较大的粒径,并可散射光以提高提取效率; 同时,氧化锌,氧化镁,硫化锌或硫化镉具有很高的功函数,可以极好地防止空穴的转变并增加激子的复合可能性,从而提高聚合物电致发光器件的发光效率 。

    DIFLUORO BENZOTRIAZOLYL SOLAR CELL POLYMERIC MATERIAL AND PREPARATION METHOD AND USE THEREOF
    13.
    发明申请
    DIFLUORO BENZOTRIAZOLYL SOLAR CELL POLYMERIC MATERIAL AND PREPARATION METHOD AND USE THEREOF 审中-公开
    二氟苯甲酸钠太阳能电池聚合材料及其制备方法及其应用

    公开(公告)号:US20140163193A1

    公开(公告)日:2014-06-12

    申请号:US14234375

    申请日:2011-09-23

    IPC分类号: C08G61/12 H01L51/00

    摘要: Disclosed are a difluoro benzotriazolyl solar cell polymeric material and preparation method and use thereof; the copolymer has a structure as represented by formula (I), wherein both R1 and R2 are alkyls from C1 to C20, and n is an integer from 10 to 100. In the difluoro benzotriazolyl solar cell polymeric material of the present invention, because the 1,2,3-benzotriazole copolymer contains two fluorine atoms, the HOMO energy level will be reduced by 0.11 eV while the fluorine-substituted 1,2,3-benzotriazole has two imido groups with strong electron-withdrawing property; the fluorine-substituted 1,2,3-benzotriazole is a heterocyclic compound with strong electron-withdrawing property, and an alkyl chain can be easily introduced to the N-position of the N—H bond of the benzotriazole; the functional group of the alkyl chain can improve solar energy conversion efficiency, thus solving the low efficiency problem of polymer solar cells.

    摘要翻译: 公开了二氟苯并三唑基太阳能电池聚合材料及其制备方法和用途; 共聚物具有由式(I)表示的结构,其中R1和R2均为C1至C20的烷基,n为10至100的整数。在本发明的二氟苯并三唑基太阳能电池聚合物材料中,因为 1,2,3-苯并三唑共聚物含有两个氟原子,HOMO能级将降低0.11eV,而氟取代的1,2,3-苯并三唑具有强吸电性的两个亚氨基; 氟取代的1,2,3-苯并三唑是具有强吸电性的杂环化合物,烷基链可以容易地引入到苯并三唑的N-H键的N位上; 烷基链的官能团可以提高太阳能转换效率,从而解决聚合物太阳能电池的低效问题。

    Altering event lifetimes
    14.
    发明授权
    Altering event lifetimes 有权
    改变事件生命周期

    公开(公告)号:US08752072B2

    公开(公告)日:2014-06-10

    申请号:US12893775

    申请日:2010-09-29

    IPC分类号: G06F9/44 G06F15/16

    CPC分类号: G06F9/542

    摘要: The present invention extends to methods, systems, and computer program products for altering event lifetimes. Embodiments of the invention include using operators in an event-processing framework (algebra) to shorten (or “clip”) the duration of events. An operator can receive a primary event stream, a clip event stream, and condition as parameters. The operator clips the lifetime of an event in the primary stream to the next event in the clip stream that fulfills the condition. Altering event lifetimes can be used to facilitate cleaning event stream state, converting point events to a continuous signal, and creating and annotating session events.

    摘要翻译: 本发明扩展到用于改变事件寿命的方法,系统和计算机程序产品。 本发明的实施例包括在事件处理框架(代数)中使用操作符来缩短(或“剪切”)事件持续时间。 操作员可以接收主事件流,剪辑事件流和条件作为参数。 操作员将主流中的事件的生存期剪辑到满足条件的剪辑流中的下一个事件。 改变事件生命周期可以用于促进清除事件流状态,将点事件转换为连续信号,以及创建和注释会话事件。

    TOP-EMITTING FLEXIBLE ORGANIC LIGHT EMISSION DIODE DEVICE AND PREPARATION METHOD THEREOF
    16.
    发明申请
    TOP-EMITTING FLEXIBLE ORGANIC LIGHT EMISSION DIODE DEVICE AND PREPARATION METHOD THEREOF 审中-公开
    顶部发光柔性有机发光二极管装置及其制备方法

    公开(公告)号:US20140124768A1

    公开(公告)日:2014-05-08

    申请号:US14122233

    申请日:2011-06-30

    IPC分类号: H01L51/52

    摘要: A top-emitting flexible organic light emission diode device and preparation method thereof are provided. The device involves overlapping a substrate, an anode layer, a hole injection layer, a hole transport layer, an emission layer, an electron transport layer, an electron injection layer and a cathode layer sequentially. The material of the cathode is scythe-silver alloy or ytterbium-silver alloy. The method for preparing the device comprises the following steps: cleaning and drying the substrate; depositing the anode layer on the surface of the substrate; overlapped depositing the hole injection layer, the hole transport layer, the emission layer, the electron transport layer and the electron injection layer sequentially on the surface of the anode layer; depositing the cathode layer on the surface of the electron injection layer to obtain the device.

    摘要翻译: 提供了顶部发射的柔性有机发光二极管器件及其制备方法。 该装置包括依次重叠基板,阳极层,空穴注入层,空穴传输层,发射层,电子传输层,电子注入层和阴极层。 阴极材料是银 - 银合金或镱 - 银合金。 制备该装置的方法包括以下步骤:清洗和干燥基材; 将阳极层沉积在衬底的表面上; 在阳极层的表面上顺序地重叠沉积空穴注入层,空穴传输层,发射层,电子传输层和电子注入层; 将阴极层沉积在电子注入层的表面上以获得该器件。

    MFG-E8 AND USES THEREOF
    17.
    发明申请
    MFG-E8 AND USES THEREOF 审中-公开
    MFG-E8及其用途

    公开(公告)号:US20140121163A1

    公开(公告)日:2014-05-01

    申请号:US14114397

    申请日:2012-04-27

    申请人: Ping Wang

    发明人: Ping Wang

    IPC分类号: A61K38/18

    CPC分类号: A61K38/1808 A61K38/1709

    摘要: Methods of treating cerebral ischemia using milk fat globule epidermal growth factor-factor VIII (MFG-E8) are disclosed, as are recombinant human MFG-E8 and its uses in pharmaceutical compositions, products and methods for treating inflammation and organ injury after ischemia/reperfusion, sepsis, and lung injury.

    摘要翻译: 公开了使用乳脂肪球表皮生长因子因子VIII(MFG-E8)治疗脑缺血的方法,重组人MFG-E8及其在药物组合物,用于治疗缺血/再灌注后炎症和器官损伤的产品和方法中的用途 ,败血症和肺损伤。

    Method for preparing linezolid and intermediates thereof
    19.
    发明授权
    Method for preparing linezolid and intermediates thereof 有权
    制备利奈唑胺的方法及其中间体

    公开(公告)号:US08658789B2

    公开(公告)日:2014-02-25

    申请号:US13144242

    申请日:2010-01-08

    IPC分类号: C07D413/10 C07C211/01

    CPC分类号: C07D263/20

    摘要: A method for preparing the linezolid (compound 1), which comprises the steps of: (1) carrying out the debenzyl reaction of compound 4 in solvent, to obtain the compound 5 or its acetic acid salt; (2) carrying out the acetylation reaction in the amino of the compound 5 or its acetic acid salt obtained in step (1) in solvent to obtain the compound 1. The intermediates to prepare the compound 1 and the acetic acid salt of compound 5. The present preparation method is easy to obtain the chiral materials and the chiral materials are cheap, the process and the post treatment are simple, the intermediate products and the end product are easy to be purified, the total yield is high, their purities are also high, this preparation method is easy to be used in the industry manufacture.

    摘要翻译: 一种制备利奈唑胺(化合物1)的方法,包括以下步骤:(1)在溶剂中进行化合物4的脱苄基反应,得到化合物5或其乙酸盐; (2)在溶剂中在步骤(1)中得到的化合物5或其乙酸盐的氨基中进行乙酰化反应,得到化合物1.制备化合物1和化合物5的乙酸盐的中间体。 本发明的制备方法易于获得手性物质,手性物料便宜,工艺和后处理简单,中间产物和最终产品容易纯化,总产率高,纯度也高 高,这种制备方法在工业制造中很容易使用。