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11.发明申请Implantable medical device with surface-eroding polyester drug delivery coating 有权具有表面侵蚀聚酯药物输送涂层的植入式医疗器械公开(公告)号：US20070190103A1
公开(公告)日：2007-08-16
申请号：US11351598
申请日：2006-02-10
Applicant: Syed Hossainy , Stephen Pacetti , Murthy Simhambhatla
Inventor： Syed Hossainy , Stephen Pacetti , Murthy Simhambhatla
IPC: A61K31/4745 , A61K31/395
CPC classification number: A61L27/34 , A61K31/395 , A61K31/4745 , A61L27/54 , A61L27/58 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , C08L67/04
Abstract: The present invention relates to an implantable medical device comprising therapeutic agents coated on the device using polyesters for the drug reservoir layer that exhibit surface-eroding characteristics.
Abstract translation: 本发明涉及可植入医疗装置，其包括使用展示表面侵蚀特征的药物储存层的聚酯涂覆在该装置上的治疗剂。
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12.发明申请公开(公告)号：US20070098758A1
公开(公告)日：2007-05-03
申请号：US11641250
申请日：2006-12-18
Applicant: Syed Hossainy , Eugene Michal , Yiwen Tang
Inventor： Syed Hossainy , Eugene Michal , Yiwen Tang
IPC: A61F2/02
CPC classification number: A61L31/16 , A61L31/10 , A61L2300/114 , A61L2300/606 , C08L67/04 , C08L71/02
Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.
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公开(公告)号：US20070065478A1
公开(公告)日：2007-03-22
申请号：US11601388
申请日：2006-11-17
Applicant: Syed Hossainy
Inventor： Syed Hossainy
IPC: A61F2/02
CPC classification number: A61L31/16 , A61L31/10 , A61L2300/252 , A61L2420/08
Abstract: Coatings for implantable medical devices and methods for fabricating the same are disclosed. The coating includes polycationic peptides, for example R7.
Abstract translation: 公开了用于可植入医疗装置的涂层及其制造方法。 涂层包括聚阳离子肽，例如R7。
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公开(公告)号：US20070005130A1
公开(公告)日：2007-01-04
申请号：US11171111
申请日：2005-06-29
Applicant: Thierry Glauser , Syed Hossainy
Inventor： Thierry Glauser , Syed Hossainy
CPC classification number: C08G63/06 , A61L31/10 , A61L31/148 , C08G2261/126 , C08L67/04
Abstract: Copolymer that includes units derived from malolactonate or malolactonic acid and coatings or medical devices formed thereof are provided.
Abstract translation: 提供了包含来源于丙二酸或异乳糖酸的单元和由其形成的涂层或医疗装置的共聚物。
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15.发明申请Coatings for implantable medical devices containing attractants for endothelial cells 审中-公开用于含内皮细胞引诱剂的可植入医疗器械的涂层公开(公告)号：US20070003589A1
公开(公告)日：2007-01-04
申请号：US11355870
申请日：2006-02-15
Applicant: Irina Astafieva , Thierry Glauser , Syed Hossainy
Inventor： Irina Astafieva , Thierry Glauser , Syed Hossainy
IPC: A61K48/00 , A61K31/4745 , A61F2/02
CPC classification number: A61L31/16 , A61K31/4745 , A61L27/34 , A61L27/54 , A61L29/085 , A61L29/14 , A61L29/16 , A61L31/10 , A61L31/14 , A61L2300/25 , A61L2300/252 , A61L2300/258 , A61L2300/40 , A61L2300/45 , A61L2300/606 , A61L2300/626 , C08L89/00
Abstract: Provided herein is a coating that includes a chemo-attractant for endothelial cells and methods of making and using the same.
Abstract translation: 本文提供的是包含内皮细胞的化学引诱剂的涂层及其制备和使用方法。
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Patent Agency Ranking
公开(公告)号：US20060286287A1
公开(公告)日：2006-12-21
申请号：US11509977
申请日：2006-08-25
Applicant: Syed Hossainy
Inventor： Syed Hossainy
CPC classification number: B05B3/1014 , A61F2/82 , B05B3/001 , B05B13/0228 , Y10S118/16
Abstract: A method of coating a medical device, such as a stent is provided. The method can include forming a polymer layer containing a drug on the device, applying a polymer melt free from any solvents to the polymer layer to form a topcoat layer, wherein the during the application of the polymer melt the migration of the drug from the polymer layer is prevented or significantly minimized.
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公开(公告)号：US20060198897A1
公开(公告)日：2006-09-07
申请号：US11213288
申请日：2005-08-26
Applicant: Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
Inventor： Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
CPC classification number: A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
Abstract: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
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18.发明申请公开(公告)号：US20060093842A1
公开(公告)日：2006-05-04
申请号：US10976551
申请日：2004-10-29
Applicant: Jessica DesNoyer , Stephen Pacetti , Syed Hossainy , Lothar Kleiner , Yiwen Tang , Gina Zhang
Inventor： Jessica DesNoyer , Stephen Pacetti , Syed Hossainy , Lothar Kleiner , Yiwen Tang , Gina Zhang
CPC classification number: C09D177/12 , A61L31/06 , A61L31/10 , Y10S623/90 , Y10T428/31725 , Y10T428/31786 , C08L77/12
Abstract: Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the PEA. The PEA polymer blend can form a coating on an implantable device, one example of which is a stent. The coating can optionally include a biobeneficial material and/or optionally with a bioactive agent. The implantable device can be used to treat or prevent a disorder such as one of atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.
Abstract translation: 本文提供了由其形成的PEA聚合物共混物和涂层或可植入装置。 PEA聚合物共混物由PEA聚合物和能够与PEA氢键合的材料形成。 PEA聚合物共混物可以在可植入装置上形成涂层，其一个实例是支架。 涂层可任选地包括生物有益材料和/或任选地含有生物活性剂。 可植入装置可用于治疗或预防动脉粥样硬化，血栓形成，再狭窄，出血，血管解剖或穿孔之一，血管动脉瘤，易损斑块，慢性完全闭塞，跛行，静脉和人造移植物的吻合增殖等障碍 导管阻塞，输尿管阻塞，肿瘤阻塞及其组合。
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公开(公告)号：US20060018944A1
公开(公告)日：2006-01-26
申请号：US11213290
申请日：2005-08-26
Applicant: Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
Inventor： Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
IPC: A61K31/727 , A61F13/00
CPC classification number: A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
Abstract: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
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20.发明申请公开(公告)号：US20060002968A1
公开(公告)日：2006-01-05
申请号：US10882506
申请日：2004-06-30
Applicant: Gordon Stewart , Gina Zhang , Nancy Kristen , Paul Consigny , Stephen Dugan , Gene Park , Christopher Feezor , Wouter Roorda , Syed Hossainy
Inventor： Gordon Stewart , Gina Zhang , Nancy Kristen , Paul Consigny , Stephen Dugan , Gene Park , Christopher Feezor , Wouter Roorda , Syed Hossainy
IPC: A61K31/4745 , A61F2/00
CPC classification number: A61K31/4745 , A61F2250/0067 , A61K31/436 , A61K31/573 , A61L31/10 , A61L31/16 , A61L2300/41 , A61L2300/416 , A61L2300/45 , A61K2300/00
Abstract: Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque.
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