公开(公告)号：US07833148B2

公开(公告)日：2010-11-16

申请号：US10498522

申请日：2002-12-13

申请人： Yasuharu Noishiki

发明人： Yasuharu Noishiki

IPC分类号： A61F2/00

CPC分类号： A61L31/145 ,  A61L27/38 ,  A61L27/52 ,  A61L27/54 ,  A61L27/58 ,  A61L31/148 ,  A61L2300/406 ,  A61L2300/414 ,  A61L2300/42

摘要： The present invention discloses a fistula formation-inducing material having a property of forming a fistula wherein cells are exposed on at least a portion of the fistula luminal surface. This material can be inserted into a living body, using a hollow tubular member, as desired. As a result, there is provided a fistula formation-inducing material which allows the formation of a fistula, reliably lined by host cells, in a living body.

摘要翻译： 本发明公开了一种具有形成瘘管的特征的瘘形成诱导材料，其中细胞暴露在瘘管腔表面的至少一部分上。 根据需要，该材料可以使用中空的管状构件插入生物体中。 结果，提供了一种瘘形成诱导材料，其允许在生物体中形成可靠地由宿主细胞排列的瘘管。

公开(公告)号：US20050084511A1

公开(公告)日：2005-04-21

申请号：US10498522

申请日：2002-12-13

申请人： Yasuharu Noishiki

发明人： Yasuharu Noishiki

IPC分类号： A61L27/00 ,  A61L27/38 ,  A61L27/52 ,  A61L27/54 ,  A61L27/58 ,  A61L31/14 ,  A61K38/18 ,  A61K31/715 ,  A61K31/727 ,  A61K38/19 ,  A61K38/48

CPC分类号： A61L31/145 ,  A61L27/38 ,  A61L27/52 ,  A61L27/54 ,  A61L27/58 ,  A61L31/148 ,  A61L2300/406 ,  A61L2300/414 ,  A61L2300/42

摘要： The present invention discloses a fistula formation-inducing material having a property of forming a fistula wherein cells are exposed on at least a portion of the fistula luminal surface. This material can be inserted into a living body, using a hollow tubular member, as desired. As a result, there is provided a fistula formation-inducing material which allows the formation of a fistula, reliably lined by host cells, in a living body.

摘要翻译： 本发明公开了一种具有形成瘘管的特征的瘘形成诱导材料，其中细胞暴露在瘘管腔表面的至少一部分上。 根据需要，该材料可以使用中空的管状构件插入生物体中。 结果，提供了一种瘘形成诱导材料，其允许在生物体中形成可靠地由宿主细胞排列的瘘管。

公开(公告)号：US09243353B2

公开(公告)日：2016-01-26

申请号：US13357150

申请日：2012-01-24

申请人： Junichi Shirokaze ,  Yasuharu Noishiki

发明人： Junichi Shirokaze ,  Yasuharu Noishiki

IPC分类号： A61F2/07 ,  D02G1/02 ,  D03D15/00 ,  A61L31/14 ,  A61L27/00 ,  D03D3/02

CPC分类号： D02G1/0206 ,  A61F2/07 ,  A61L27/00 ,  A61L31/146 ,  D03D1/00 ,  D03D3/02 ,  D03D15/0061 ,  D10B2401/10 ,  D10B2509/06

摘要： Provided is a stent graft that has superior prevention of endoleakage due to being resistant to creasing, and has superior prevention of graft migration as a result of promoting cell infiltration into gaps among microfibers in a dispersed state and forming an integrated structure with the cells in the landing zone of the stent. The stent graft according to the present invention is a stent graft comprising a stent graft fabric that has microfiber bundles consisting essentially of microfilaments having a filament linear density of 0.5 dtex or less, and said microfiber bundles having a total linear density of 10 to 60 dtex/120 to 3000 filaments, for the warp and/or weft, and in which the porosity of the microfiber bundles is 30% to 95%, wherein said stent graft has said stent graft fabric being located in at least 1 cm range from the central end.

摘要翻译： 提供一种支架移植物，其具有优异的防止由于抗皱纹而引起的内漏，并且由于促进细胞渗透到分散状态的微纤维之间的间隙中而形成与该细胞的整体结构的结果，具有优异的移植移植 支架着陆区。 根据本发明的支架移植物是一种支架移植物，其包括具有基本上由细丝线密度为0.5dtex以下的微丝组成的超细纤维束的支架移植物织物，所述超细纤维束的总线密度为10〜60dtex / 120至3000根长丝，用于经纱和/或纬纱，其中微纤维束的孔隙率为30％至95％，其中所述支架移植物具有所述支架移植物织物位于距中心至少1cm的范围内 结束。

公开(公告)号：US20120004673A1

公开(公告)日：2012-01-05

申请号：US13138648

申请日：2010-03-03

申请人： Yasuharu Noishiki

发明人： Yasuharu Noishiki

IPC分类号： A61B17/00 ,  B05D5/00 ,  C23F1/00

CPC分类号： C23C14/48 ,  A61F2/06 ,  A61L27/34 ,  A61L27/502 ,  A61L27/507 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/452

摘要： Provided are a medical material for in vivo implantation which causes no retention of an exudates in the surroundings and yet shows a flexibility; a method for controlling the content of a softening agent and/or a moisturizing agent in the medical material; and a method for producing the medical material for in vivo implantation. When a hybrid medical material for in vivo implantation, which comprises a bioabsorbable material containing a softening agent and/or a moisturizing agent and a non-bioabsorbable porous base material, contains large amount of the softening agent and/or a moisturizing agent, retention of an exudates occurs in the surroundings of the medical material. It is found out that this phenomenon is a side effect of the softening agent and/or a moisturizing agent. To prevent this side effect, a medical material for in vivo implantation in which the content of a softening agent and/or a moisturizing agent is controlled less than 20 wt %; a method for controlling said content; and a method for producing a medical material for in vivo implantation are provided.

摘要翻译： 提供了用于体内植入的医疗材料，其不会在周围环境中留下渗出物，并且显示出柔性; 用于控制医疗材料中的软化剂和/或保湿剂的含量的方法; 以及用于体内植入的医疗材料的制造方法。 当用于体内植入的混合医疗材料（其包含含有软化剂和/或保湿剂的生物可吸收材料）和非生物吸收性多孔基材时，含有大量的软化剂和/或保湿剂，保留 渗出物发生在医疗材料的周围。 发现这种现象是软化剂和/或保湿剂的副作用。 为了防止这种副作用，将软化剂和/或保湿剂的含量控制在小于20重量％的体内植入用医疗材料; 一种用于控制所述内容的方法; 提供了用于体内植入的医疗材料的制造方法。

公开(公告)号：US20100030105A1

公开(公告)日：2010-02-04

申请号：US11910411

申请日：2006-03-26

申请人： Yasuharu Noishiki ,  Yasuhiro Fujita ,  Akihiro Ametani ,  Yasuo Seki

发明人： Yasuharu Noishiki ,  Yasuhiro Fujita ,  Akihiro Ametani ,  Yasuo Seki

IPC分类号： A61B10/00

CPC分类号： A61B10/025 ,  A61B2010/0258

摘要： [Problems] To provide a double needle enabling easy centesis in bones and cortex and easy alignment of an inner needle with an outer needle in an angular direction and capable of transmitting torque when the inner needle and the outer needle are rotated simultaneously.[Means for Solving Problems] This double needle (10) for medical treatment comprises the cylindrical outer needle (11) having an edge part (26) at its tip and the solid inner needle (12) detachably stored in the outer needle. When the outer needle (11) is rotated about its major axis, the rotating diameter of the edge part (26) is larger than the rotating diameter of a body part. Also, the double needle comprises a corotation mechanism (20) for the outer needle (11) and the inner needle (12).

摘要翻译： [问题]提供双针，使得能够容易地在骨骼和皮质中产生中心，并且容易地使内针与外针在角度方向上对准并且当内针和外针同时旋转时能够传递扭矩。 [解决问题的手段]用于医疗的双重针（10）包括其顶端具有边缘部分（26）的圆柱形外针（11）和可拆卸地存储在外针中的实心内针（12）。 当外针（11）围绕其长轴旋转时，边缘部分（26）的旋转直径大于主体部分的旋转直径。 此外，双针包括用于外针（11）和内针（12）的共旋转机构（20）。

公开(公告)号：US20090187116A1

公开(公告)日：2009-07-23

申请号：US11547559

申请日：2005-04-05

申请人： Yasuharu Noishiki ,  Yasuhiro Fujita ,  Akihiro Ametani ,  Yasuo Seki

发明人： Yasuharu Noishiki ,  Yasuhiro Fujita ,  Akihiro Ametani ,  Yasuo Seki

IPC分类号： A61B10/00 ,  A61B17/00

CPC分类号： A61B10/025 ,  A61B2010/0258 ,  A61B2017/320733

摘要： Using a bended puncturing needle, a through hole from the greater trochanter of a long tubular bone to the bone marrow cavity is formed, the catheter 61a, 61b is passed into the through hole, a physiological salt solution is injected from one of the catheter 61b, and the physiological salt solution and the bone marrow is stirred by the stirring wire 68, the obtained mixed liquid is aspirated and harvested by another catheter 61a, thereby a large amount of the bone marrow is harvested. A method enabling easy and a large amount harvesting of the bone marrow from long tubular bones such as femurs, in which a multi-lumen catheter can also be used as a catheter.

摘要翻译： 使用弯曲的穿刺针，形成从长管状骨的大转子到骨髓腔的通孔，导管61a，61b进入通孔，从导管61b中的一个注射生理盐溶液 ，通过搅拌丝68搅拌生理盐溶液和骨髓，将所得到的混合液吸引并通过另一个导管61a收获，从而收获大量的骨髓。 一种能够从诸如股骨的长管状骨头容易且大量收获骨髓的方法，其中多腔导管也可以用作导管。

公开(公告)号：US4695280A

公开(公告)日：1987-09-22

申请号：US910330

申请日：1986-09-22

申请人： Koji Watanabe ,  Miyoshi Okamoto ,  Yuichi Mori ,  Yasuharu Noishiki

发明人： Koji Watanabe ,  Miyoshi Okamoto ,  Yuichi Mori ,  Yasuharu Noishiki

IPC分类号： A61L27/00 ,  A61F2/06 ,  A61L27/16 ,  A61L27/18

CPC分类号： A61L27/18 ,  A61F2/06 ,  A61L27/16 ,  A61L27/507

摘要： The present invention relates to an artificial vascular graft having ultra fine fibers smaller than 0.5 denier in fineness as part of the inner wall. The artificial vascular graft of this invention is very flexible and produces very low blood leakage. The ease of performing anastomoses is greatly improved. Because of the ultra fine fiber there are many sites to which live cells adhere, the adaptability of the live cells to the fibers of the vascular graft increases, an excellent antithrombotic effect is exerted by the vascular graft, and the formation of the endothelial cells is satisfactory and is observed at a very early stage.

摘要翻译： 本发明涉及一种人造血管移植物，其具有作为内壁的一部分的细度小于0.5旦尼尔的超细纤维。 本发明的人造血管移植物非常灵活，产​​生非常低的血液渗漏。 进行吻合的容易性大大提高。 由于超细纤维存在活细胞粘附的许多部位，活细胞对血管移植物的纤维的适应性增加，血管移植物发挥优异的抗血栓形成作用，内皮细胞的形成是 令人满意，并且在很早的阶段被观察到。