公开(公告)号：US10031138B2

公开(公告)日：2018-07-24

申请号：US13747290

申请日：2013-01-22

Applicant: University of Washington through its Center for Commercialization

Inventor： Shaoyi Jiang ,  Norman David Brault, Jr. ,  Harihara S. Sundaram ,  Chun-Jen Huang ,  Qiuming Yu ,  Yuting Li

IPC: G01N33/543 ,  G01N21/552

CPC classification number: G01N33/54393 ,  G01N21/553

Abstract: Hierarchical films with structurally regulated functionalities through the integration of two-dimensional and three-dimensional structures to achieve ultra low nonspecific binding and high loading of molecular recognition elements, and methods for making and using the films.

公开(公告)号：US09394435B2

公开(公告)日：2016-07-19

申请号：US14457801

申请日：2014-08-12

Applicant: University of Washington through its Center for Commercialization

Inventor： Shaoyi Jiang ,  Hong Xue ,  Wei Yang ,  Louisa R. Carr

IPC: C08L33/10 ,  A61K41/00 ,  A61L27/34 ,  A61L27/52 ,  A61L29/08 ,  A61L29/14 ,  A61L31/10 ,  A61L31/14 ,  C07C229/12 ,  C08F26/02

CPC classification number: C08L33/14 ,  A61K41/0019 ,  A61L27/34 ,  A61L27/52 ,  A61L29/085 ,  A61L29/145 ,  A61L31/10 ,  A61L31/145 ,  C07C229/12 ,  C08F26/02 ,  C08J3/075 ,  C08J2433/14 ,  C08L33/10 ,  C08L2201/54 ,  C08L2312/00 ,  C12Q1/54 ,  C12Y101/03004 ,  G01N2333/904 ,  Y10T428/31786

Abstract: Zwitterionic crosslinking agents, crosslinked zwitterionic hydrogels prepared from copolymerization of zwitterionic monomers with the zwitterionic crosslinking agent, methods for making crosslinked zwitterionic hydrogels, and devices that include and methods that use the crosslinked zwitterionic hydrogels.

Abstract translation: 两性离子交联剂，由两性离子交联剂的两性离子单体共聚制备的交联的两性离子水凝胶，用于制备交联的两性离子水凝胶的方法，以及包括使用交联的两性离子水凝胶的方法的装置。

公开(公告)号：US20150037598A1

公开(公告)日：2015-02-05

申请号：US14457801

申请日：2014-08-12

Applicant: University of Washington through its Center for Commercialization

Inventor： Shaoyi Jiang ,  Hong Xue ,  Wei Yang ,  Louisa R. Carr

IPC: C08L33/10

CPC classification number: C08L33/14 ,  A61K41/0019 ,  A61L27/34 ,  A61L27/52 ,  A61L29/085 ,  A61L29/145 ,  A61L31/10 ,  A61L31/145 ,  C07C229/12 ,  C08F26/02 ,  C08J3/075 ,  C08J2433/14 ,  C08L33/10 ,  C08L2201/54 ,  C08L2312/00 ,  C12Q1/54 ,  C12Y101/03004 ,  G01N2333/904 ,  Y10T428/31786

Abstract: Zwitterionic crosslinking agents, crosslinked zwitterionic hydrogels prepared from copolymerization of zwitterionic monomers with the zwitterionic crosslinking agent, methods for making crosslinked zwitterionic hydrogels, and devices that include and methods that use the crosslinked zwitterionic hydrogels.

Abstract translation: 两性离子交联剂，由两性离子交联剂的两性离子单体共聚制备的交联的两性离子水凝胶，用于制备交联的两性离子水凝胶的方法，以及包括使用交联的两性离子水凝胶的方法的装置。

公开(公告)号：US20130244249A1

公开(公告)日：2013-09-19

申请号：US13747290

申请日：2013-01-22

Applicant: University of Washington through its Center for Commercialization

Inventor： Shaoyi Jiang ,  Norman David Brault, JR. ,  Harihara S. Sundaram ,  Chun-Jen Huang ,  Qiuming Yu ,  Yuting Li

IPC: G01N33/543

CPC classification number: G01N33/54393 ,  G01N21/553

Abstract: Hierarchical films with structurally regulated functionalities through the integration of two-dimensional and three-dimensional structures to achieve ultra low nonspecific binding and high loading of molecular recognition elements, and methods for making and using the films.

Abstract translation: 通过整合二维和三维结构来获得具有结构调节功能的分层膜，以实现超低非特异性结合和分子识别元件的高负载，以及制备和使用膜的方法。

公开(公告)号：US20190154683A1

公开(公告)日：2019-05-23

申请号：US16042883

申请日：2018-07-23

Applicant: University of Washington through its Center for Commercialization

Inventor： Shaoyi Jiang ,  Norman David Brault, JR. ,  Harihara S. Sundaram ,  Chun-Jen Huang ,  Qiuming Yu ,  Yuting Li

IPC: G01N33/543

Abstract: Hierarchical films with structurally regulated functionalities through the integration of two-dimensional and three-dimensional structures to achieve ultra low nonspecific binding and high loading of molecular recognition elements, and methods for making and using the films.

公开(公告)号：US10130716B2

公开(公告)日：2018-11-20

申请号：US14526846

申请日：2014-10-29

Applicant: University of Washington through its Center for Commercialization

Inventor： Shaoyi Jiang ,  Andrew Keefe ,  Hong Xue

IPC: A61K38/48 ,  A61K47/48

Abstract: Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates.

公开(公告)号：US20150157732A1

公开(公告)日：2015-06-11

申请号：US14526846

申请日：2014-10-29

Applicant: University of Washington through its Center for Commercialization

Inventor： Shaoyi Jiang ,  Andrew Keefe ,  Hong Xue

IPC: A61K47/48 ,  A61K38/48

CPC classification number: A61K47/48176 ,  A61K38/4826 ,  A61K47/58 ,  C12Y304/21001

Abstract: Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates.

Abstract translation: 两性离子聚合物和混合电荷共聚物生物共轭物，制备和使用生物共轭物的方法。

公开(公告)号：US20150133609A1

公开(公告)日：2015-05-14

申请号：US14539886

申请日：2014-11-12

Applicant: University of Washington through its Center for Commercialization

Inventor： Shaoyi Jiang ,  Tao Bai

IPC: C08G73/02

CPC classification number: C08G73/026 ,  C08G73/0266

Abstract: Zwitterionic and mixed charge conducting polymers, surfaces modified to include the polymers, bulk constructs that include the polymers, and methods for using the polymers.

Abstract translation: 两性离子和混合电荷导电聚合物，修饰成包括聚合物的表面，包括聚合物的本体构造物，以及使用该聚合物的方法。