公开(公告)号：US20080194959A1

公开(公告)日：2008-08-14

申请号：US11597196

申请日：2005-05-23

申请人： Shih-Ping Wang ,  Wei Zhang ,  Jiayu Chen ,  Zengpin Yu

发明人： Shih-Ping Wang ,  Wei Zhang ,  Jiayu Chen ,  Zengpin Yu

IPC分类号： A61B8/13

CPC分类号： A61B8/0825 ,  A61B8/406 ,  A61B8/4218 ,  A61B8/4281 ,  A61B8/483 ,  A61B8/54

摘要： An apparatus and related methods for scanning a breast are described, the apparatus comprising a frame defining an orifice shaped to allow the breast to be received therein, a compressive member secured to the frame across the orifice that compresses the received breast toward the patient's chest wall, and a transducer positioned in acoustic communication with the compressive member for imaging the breast therethrough. The frame holds a reservoir of acoustically conductive fluid that maintains the transducer in acoustic communication with the compressive member. In different preferred embodiments having different advantages, the compressive member comprises a flexible elastic membrane, a flexible inelastic membrane, or a rigid sonolucent plastic preformed into the shape of a chestwardly-compressed breast. Where the transducer comprises one or more linear array probes, various probe orientations and trajectories are described for generating a three-dimensional volumetric representation of the breast having reduced nipple shadow effects.

摘要翻译： 描述了一种用于扫描乳房的装置和相关方法，所述装置包括限定形状以允许乳房被容纳在其中的孔口的框架;压缩构件，其被固定到穿过所述孔口的框架，所述压缩构件将接收的乳房压缩到患者的胸壁 以及与所述压缩构件声学连通的换能器，用于使乳房通过其成像。 框架保持导电流体的储存器，其将换能器保持与压缩构件声学连通。 在具有不同优点的不同优选实施例中，压缩构件包括柔性弹性膜，柔性非弹性膜或预先形成胸部压缩乳房形状的刚性声光塑料。 在换能器包括一个或多个线性阵列探针的情况下，描述了用于产生具有降低的乳头阴影效应的乳房的三维体积表示的各种探针取向和轨迹。

公开(公告)号：US08162833B2

公开(公告)日：2012-04-24

申请号：US12890374

申请日：2010-09-24

申请人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

发明人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

IPC分类号： A61B8/00

CPC分类号： A61B8/5238 ,  A61B6/463 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/0825 ,  A61B8/13 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/463 ,  A61B8/465 ,  A61B8/466 ,  A61B8/467 ,  A61B8/565

摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.

摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。

公开(公告)号：US20100331699A1

公开(公告)日：2010-12-30

申请号：US10560200

申请日：2004-06-18

申请人： Zengpin Yu ,  Danhua Zhao ,  Thomas P. Neff ,  Wei Zhang ,  Shih-Ping Wang

发明人： Zengpin Yu ,  Danhua Zhao ,  Thomas P. Neff ,  Wei Zhang ,  Shih-Ping Wang

IPC分类号： A61B8/14

CPC分类号： A61B8/4477 ,  A61B8/0825 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/5238 ,  Y10T29/49005

摘要： A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system (202) is modified with an FFBU toolkit to create a dual-capability ultrasound system (200), the dual-capability ultrasound system (200) being able to accommodate both general-purpose ultrasound functionality and FFBU functionality, using a single ultrasound engine (112). Among other advantages, real-world clinical environments may enjoy cost savings for initial system procurement, space savings on clinic floors, easier and less expensive system upgrades, and the ability to use a single system and user interface for both FFBU screening and for follow-up diagnosis, biopsy, etc. Among other advantages from an ultrasound manufacturer's perspective are the ability to quickly and/or more easily come to market with an FFBU-related offering by modifying their existing general-purpose ultrasound systems (202) with FFBU toolkits to quickly create dual-capability ultrasound systems (200).

摘要翻译： 描述了在单个系统中提供全场乳房超声（FFBU）功能和通用超声功能的模块化，灵活的架构。 传统的通用超声系统（202）用FFBU工具包修改以创建双能力超声系统（200），双能力超声系统（200）能够容纳通用超声功能和FFBU 功能，使用单个超声引擎（112）。 除了其他优点之外，现实世界的临床环境可以节省初始系统采购成本，临床楼层节省空间，更便宜和更便宜的系统升级，以及使用单个系统和用户界面进行FFBU筛选和跟踪的功能， 诊断，活检等。超声波制造商的观点还有其他优点，即通过使用FFBU工具包修改现有的通用超声波系统（202），通过与FFBU相关的产品快速和/或更容易上市。 快速创建双功能超声系统（200）。

公开(公告)号：US07828733B2

公开(公告)日：2010-11-09

申请号：US12545201

申请日：2009-08-21

申请人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

发明人： Wei Zhang ,  Shih-Ping Wang ,  Jiayu Chen ,  Zengpin Yu ,  Tommy Earl Cupples ,  Thomas P. Neff ,  Michael E. Reed

IPC分类号： A61B8/00

CPC分类号： A61B8/5238 ,  A61B6/463 ,  A61B6/502 ,  A61B6/5247 ,  A61B6/563 ,  A61B8/0825 ,  A61B8/13 ,  A61B8/406 ,  A61B8/4281 ,  A61B8/4405 ,  A61B8/462 ,  A61B8/463 ,  A61B8/465 ,  A61B8/466 ,  A61B8/467 ,  A61B8/565

摘要： Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.

摘要翻译： 描述了在交互式用户界面上显示乳房超声信息，用户界面在辅助超声乳腺X线照相术环境和/或仅超声乳腺X线照相术环境中有用。 通过成对显示对应于左乳房和右乳房中类似的板状子体积的双层比较来促进双边比较。 描述了冠状厚片成像和冠状厚片图像之间和之间方便的导航。 在一个优选实施例中，乳头标记被显示为表示其上的乳头位置的投影的冠状厚片图像。 还显示方便的胸部图标，包括以反映光标和乳头标记之间的相对位置的方式可变地设置在其上的光标位置指示器。 优选地，乳房图标被配置为至少大致类似于时钟面，时钟面的中心表示乳头标记位置。 还描述了厚片图像内和书签中心和CAD标记为中心的导航。

公开(公告)号：US20080177163A1

公开(公告)日：2008-07-24

申请号：US12017969

申请日：2008-01-22

申请人： Shih-Ping Wang ,  Xuefeng Cheng ,  Zengpin Yu

发明人： Shih-Ping Wang ,  Xuefeng Cheng ,  Zengpin Yu

IPC分类号： A61B5/1455

CPC分类号： A61B5/0073 ,  A61B5/14553 ,  A61B5/4064 ,  A61B5/6814 ,  A61B2562/0233 ,  A61B2562/046

摘要： Methods, systems, and related computer program products for non-invasive monitoring of a biological volume, such as a human brain, are described. In one preferred embodiment, each of a plurality of optical sources emits optical radiation into the biological volume each of a plurality of optical detectors detects optical radiation impinging thereupon from the biological volume. The optical measurements are processed to compute a requisite property value associated with each source-detector pair. For each source-detector pair, a volumetric basis region corresponding thereto is weighted by the requisite property value, the volumetric basis region being predetermined and representative of an estimated subvolume of the biological volume encountered by optical radiation emitted from that source and propagating to that detector. The weighted volumetric basis regions are accumulated into a volumetric cumulative array, and a display output is generated based at least in part on the volumetric cumulative array.

摘要翻译： 描述了用于非侵入性监测生物体积的方法，系统和相关的计算机程序产品，例如人类大脑。 在一个优选实施例中，多个光源中的每一个将光辐射发射到生物体积中，多个光学检测器中的每一个检测器从生物体积检测入射的光辐射。 处理光学测量以计算与每个源 - 检测器对相关联的必要属性值。 对于每个源 - 检测器对，与其对应的体积基础区域由所需的属性值加权，体积基础区域是预定的，并且代表从该源发射并传播到该检测器的光辐射遇到的生物体积的估计子体积 。 加权体积基础区域被累积到体积累积阵列中，并且至少部分地基于体积累积阵列生成显示输出。

公开(公告)号：US08184882B2

公开(公告)日：2012-05-22

申请号：US13072006

申请日：2011-03-25

申请人： Zengpin Yu ,  Shih-Ping Wang

发明人： Zengpin Yu ,  Shih-Ping Wang

IPC分类号： G06K9/00 ,  G06Q10/00 ,  G06Q50/00

CPC分类号： G06K9/00 ,  A61B6/502 ,  A61B6/5235 ,  A61B6/5247 ,  A61B8/0825 ,  A61B8/4405 ,  A61B8/5238 ,  G06F19/00 ,  G06Q10/06311 ,  G06Q10/063116 ,  G06Q50/22 ,  G06Q50/24

摘要： A system, computer program product, and related methods are described for obtaining, processing, and/or and archiving full-field breast image data, such as full-field breast ultrasound (FFBU) data, in a manner that promotes ready integration with current x-ray mammogram-based breast cancer screening methodologies, and which can alternatively be used to support a full-field-only environment. Two-dimensional thick-slice images computed from a three-dimensional data volume are used to facilitate efficient archiving for a breast imaging session, the two-dimensional thick-slice images corresponding to slab-like subvolumes of the breast. Clinician data overload problems that can arise from the existence of large amounts of three-dimensional full-field breast image data are reduced. Archive space is also preserved while still providing sufficient information data for future reference purposes. Related adjunctive full-field workflow methods are also described. The described embodiments are applicable to FFBU imaging and other full-field breast imaging modalities such as MRI, CT, PET, and others.

摘要翻译： 描述了用于获得，处理和/或归档全场乳房图像数据（例如全场乳房超声（FFBU）数据）的系统，计算机程序产品和相关方法，以促进与当前的现场集成的方式 基于X射线乳腺X线摄影的乳腺癌筛查方法，可替代地可用于支持全场仅有的环境。 使用从三维数据体积计算的二维厚片图像来促进乳房成像会话的有效归档，对应于乳房的板状子体积的二维厚片图像。 减少了由存在大量三维全场乳房图像数据引起的临床医生数据过载问题。 存档空间也得到保留，同时仍然提供足够的信息数据以备将来参考。 还描述了相关的辅助全字段工作流程方法。 所描述的实施例可应用于FFBU成像和其他全场乳房成像模式，例如MRI，CT，PET等。

公开(公告)号：US20110288414A1

公开(公告)日：2011-11-24

申请号：US13072006

申请日：2011-03-25

申请人： Zengpin YU ,  Shih-Ping Wang

发明人： Zengpin YU ,  Shih-Ping Wang

IPC分类号： A61B8/00 ,  A61B6/04

CPC分类号： G06K9/00 ,  A61B6/502 ,  A61B6/5235 ,  A61B6/5247 ,  A61B8/0825 ,  A61B8/4405 ,  A61B8/5238 ,  G06F19/00 ,  G06Q10/06311 ,  G06Q10/063116 ,  G06Q50/22 ,  G06Q50/24

摘要： A system, computer program product, and related methods are described for obtaining, processing, and/or and archiving full-field breast image data, such as full-field breast ultrasound (FFBU) data, in a manner that promotes ready integration with current x-ray mammogram-based breast cancer screening methodologies, and which can alternatively be used to support a full-field-only environment. Two-dimensional thick-slice images computed from a three-dimensional data volume are used to facilitate efficient archiving for a breast imaging session, the two-dimensional thick-slice images corresponding to slab-like subvolumes of the breast. Clinician data overload problems that can arise from the existence of large amounts of three-dimensional full-field breast image data are reduced. Archive space is also preserved while still providing sufficient information data for future reference purposes. Related adjunctive full-field workflow methods are also described. The described embodiments are applicable to FFBU imaging and other full-field breast imaging modalities such as MRI, CT, PET, and others.

摘要翻译： 描述了用于获得，处理和/或归档全场乳房图像数据（例如全场乳房超声（FFBU）数据）的系统，计算机程序产品和相关方法，以促进与当前的现场集成的方式 基于X射线乳腺X线摄影的乳腺癌筛查方法，可替代地可用于支持全场仅有的环境。 使用从三维数据体积计算的二维厚片图像来促进乳房成像会话的有效归档，对应于乳房的板状子体积的二维厚片图像。 减少了由存在大量三维全场乳房图像数据引起的临床医生数据过载问题。 存档空间也得到保留，同时仍然提供足够的信息数据以备将来参考。 还描述了相关的辅助全字段工作流程方法。 所描述的实施例可应用于FFBU成像和其他全场乳房成像模式，例如MRI，CT，PET等。

公开(公告)号：US07940966B2

公开(公告)日：2011-05-10

申请号：US10530447

申请日：2003-11-25

申请人： Zengpin Yu ,  Shih-Ping Wang

发明人： Zengpin Yu ,  Shih-Ping Wang

IPC分类号： G06K9/00

CPC分类号： G06K9/00 ,  A61B6/502 ,  A61B6/5235 ,  A61B6/5247 ,  A61B8/0825 ,  A61B8/4405 ,  A61B8/5238 ,  G06F19/00 ,  G06Q10/06311 ,  G06Q10/063116 ,  G06Q50/22 ,  G06Q50/24

摘要： A system, computer program product, and related methods are described for obtaining, processing, and/or and archiving full-field breast image data, such as full-field breast ultrasound (FFBU) data, in a manner that promotes ready integration with current x-ray mammogram-based breast cancer screening methodologies, and which can alternatively be used to support a full-field-only environment. Two-dimensional thick-slice images computed from a three-dimensional data volume are used to facilitate efficient archiving for a breast imaging session, the two-dimensional thick-slice images corresponding to slab-like subvolumes of the breast. Clinician data overload problems that can arise from the existence of large amounts of three-dimensional full-field breast image data are reduced. Archive space is also preserved while still providing sufficient information data for future reference purposes. Related adjunctive full-field workflow methods are also described. The described embodiments are applicable to FFBU imaging and other full-field breast imaging modalities such as MRI, CT, PET, and others.

摘要翻译： 描述了用于获得，处理和/或归档全场乳房图像数据（例如全场乳房超声（FFBU）数据）的系统，计算机程序产品和相关方法，以促进与当前的现场集成的方式 基于X射线乳腺X线摄影的乳腺癌筛查方法，可替代地可用于支持全场仅有的环境。 使用从三维数据体积计算的二维厚片图像来促进乳房成像会话的有效归档，对应于乳房的板状子体积的二维厚片图像。 减少了由存在大量三维全场乳房图像数据引起的临床医生数据过载问题。 存档空间也得到保留，同时仍然提供足够的信息数据以备将来参考。 还描述了相关的辅助全字段工作流程方法。 所描述的实施例可应用于FFBU成像和其他全场乳房成像模式，例如MRI，CT，PET等。

公开(公告)号：US20060173303A1

公开(公告)日：2006-08-03

申请号：US10530447

申请日：2003-11-25

申请人： Zengpin Yu ,  Shih-Ping Wang

发明人： Zengpin Yu ,  Shih-Ping Wang

IPC分类号： A61B8/00

CPC分类号： G06K9/00 ,  A61B6/502 ,  A61B6/5235 ,  A61B6/5247 ,  A61B8/0825 ,  A61B8/4405 ,  A61B8/5238 ,  G06F19/00 ,  G06Q10/06311 ,  G06Q10/063116 ,  G06Q50/22 ,  G06Q50/24

摘要： A system, computer program product, and related methods are described for obtaining, processing, and/or and archiving full-field breast image data, such as full-field breast ultrasound (FFBU) data, in a manner that promotes ready integration with current x-ray mammogram-based breast cancer screening methodologies, and which can alternatively be used to support a full-field-only environment, Two-dimensional thick-slice images computed from a three-dimensional data volume are used to facilitate efficient archiving for a breast imaging session, the two-dimensional thick-slice images corresponding to slab-like subvolumes of the breast. Clinician data overload problems that can arise from the existence of large amounts of three-dimensional full-field breast image data are reduced. Archive space is also preserved while still providing sufficient information data for future reference purposes. Related adjunctive full-field workflow methods are also described. The described embodiments are applicable to FFBU imaging and other full-field breast imaging modalities such as MRI, CT, PET, and others.

摘要翻译： 描述了用于获得，处理和/或归档全场乳房图像数据（例如全场乳房超声（FFBU）数据）的系统，计算机程序产品和相关方法，以促进与当前的现场集成的方式 基于x射线乳腺X线摄影的乳腺癌筛查方法，可替代地可用于支持全场仅环境，使用从三维数据量计算的二维厚片图像来促进有效的归档 乳房成像会话，对应于乳房的板状子体积的二维厚片图像。 减少了由存在大量三维全场乳房图像数据引起的临床医生数据过载问题。 存档空间也得到保留，同时仍然提供足够的信息数据以备将来参考。 还描述了相关的辅助全字段工作流程方法。 所描述的实施例可应用于FFBU成像和其他全场乳房成像模式，例如MRI，CT，PET等。

公开(公告)号：US09826958B2

公开(公告)日：2017-11-28

申请号：US14044842

申请日：2013-10-02

申请人： Wei Zhang ,  Shih-Ping Wang ,  Alexander Schneider ,  Nico Karssemeijer

发明人： Wei Zhang ,  Shih-Ping Wang ,  Alexander Schneider ,  Nico Karssemeijer

IPC分类号： A61B8/08 ,  G06T7/00

CPC分类号： A61B8/0825 ,  A61B8/5238 ,  G06T7/0012 ,  G06T2207/10132 ,  G06T2207/30068

摘要： A method and system for processing and displaying breast ultrasound information is described. A 2D feature weighted volumetric coronal image as a “guide” or “road map” is generated from the 3D ultrasound data volume to represent the 3D dataset with the goal of emphasizing abnormalities within the breast while excluding non-breast structures, particularly those external to the breast such as ribs and chest wall.