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11.发明申请公开(公告)号：US20190086436A1
公开(公告)日：2019-03-21
申请号：US16193452
申请日：2018-11-16
发明人： Stephen LaChance , Alyssa Shedlosky , Alexander Clark , Redeat Girma Alemu , Craig Bark , Steven Charles Rotundo , Michael T. Vansickler
CPC分类号： G01N35/1072 , B01L3/021 , B01L3/0275 , B01L3/50273 , B01L3/527 , B01L2200/143 , B01L2200/148 , B01L2400/043 , B01L2400/0487 , B01L2400/049 , B01L2400/06 , B01L2400/0666 , G01N1/14 , G01N1/18 , G01N35/10 , G01N35/1016 , G01N2001/1418 , G01N2035/1027
摘要： Automated pipetting systems and methods are disclosed for aspirating and dispensing fluids, particularly biological samples. In one aspect, a liquid dispenser includes a manifold and one or more pipette channels. The manifold includes a vacuum channel, a pressure channel, and a plurality of lanes. Each lane includes an electrical connector, a port to the pressure channel, and a port to the vacuum channel. The pipette channels can be modular. Each pipette channel includes a single dispense head and can be selectively and independently coupled to any one lane of the plurality of lanes. In some aspects, a valve in the pipette channel is in simultaneous fluid communication with a pressure port and a vacuum port of the manifold. The valve selectively diverts gas under pressure and gas under vacuum to the dispense head in response to control signals received through the electrical connector of the manifold.
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公开(公告)号：US20150212052A1
公开(公告)日：2015-07-30
申请号：US14528118
申请日：2014-10-30
发明人： Jin Soo PARK , Soo Hong KIM
CPC分类号： G01N35/10 , B01L3/50273 , B01L9/527 , B01L2300/0816 , B01L2400/0481 , G01N35/00029 , G01N2035/00128 , G01N2035/1027
摘要： Disclosed are a sample inspection apparatus and a control method thereof. The sample inspection apparatus includes a housing, a cartridge insertable into one side of the housing and configured to receive a sample, a pressing member disposed within the housing and configured to press the cartridge to inspect the sample, a fluid storage part configured to transfer a fluid to the pressing member so that the pressing member presses the cartridge, and a fluid supply part configured to supply the fluid into the fluid storage part.
摘要翻译： 公开了一种样本检查装置及其控制方法。 样品检查装置包括壳体，可插入到壳体的一侧并被构造成接收样品的盒，设置在壳体内并构造成按压盒以检查样品的按压构件，被配置为传送 流体到按压构件，使得按压构件按压盒;以及流体供给部，被配置为将流体供应到流体存储部。
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13.发明公开公开(公告)号：US20240159790A1
公开(公告)日：2024-05-16
申请号：US18514091
申请日：2023-11-20
发明人： Stephen LaChance , Alyssa Shedlosky , Alexander Clark , Redeat Girma Alemu , Craig Bark , Steven Charles Rotundo , Michael T. Vansickler
CPC分类号： G01N35/1072 , B01L3/021 , B01L3/0275 , B01L3/50273 , B01L3/527 , G01N1/14 , G01N1/18 , G01N35/10 , G01N35/1016 , B01L2200/143 , B01L2200/148 , B01L2400/043 , B01L2400/0487 , B01L2400/049 , B01L2400/06 , B01L2400/0666 , G01N2001/1418 , G01N2035/1027
摘要： Automated pipetting systems and methods are disclosed for aspirating and dispensing fluids, particularly biological samples. In one aspect, a liquid dispenser includes a manifold and one or more pipette channels. The manifold includes a vacuum channel, a pressure channel, and a plurality of lanes. Each lane includes an electrical connector, a port to the pressure channel, and a port to the vacuum channel. The pipette channels can be modular. Each pipette channel includes a single dispense head and can be selectively and independently coupled to any one lane of the plurality of lanes. In some aspects, a valve in the pipette channel is in simultaneous fluid communication with a pressure port and a vacuum port of the manifold. The valve selectively diverts gas under pressure and gas under vacuum to the dispense head in response to control signals received through the electrical connector of the manifold.
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公开(公告)号：US11879875B2
公开(公告)日：2024-01-23
申请号：US17203021
申请日：2021-03-16
CPC分类号： G01N30/16 , G01N35/1095 , G01N2035/1027
摘要： A liquid chromatography sample manager includes a sampling mechanism; a sample platter mounted in the sampling mechanism, the sample platter configured to rotate about a first vertical axis; a needle arm mounted within the sampling mechanism, the needle arm configured to rotate about a second vertical axis; and a sample delivery system in fluidic communication with solvent delivery system, the sample delivery system including a sample needle attached to the needle arm, the sample delivery system configured to transfer a first sample from a first sample vial carrier located in the sample platter into a chromatographic flow stream.
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15.发明授权公开(公告)号：US11828767B2
公开(公告)日：2023-11-28
申请号：US17406482
申请日：2021-08-19
发明人： Stephen LaChance , Alyssa Shedlosky , Alexander Clark , Redeat Girma Alemu , Craig Bark , Steven Charles Rotundo , Michael T. Vansickler
CPC分类号： G01N35/1072 , B01L3/021 , B01L3/0275 , B01L3/50273 , B01L3/527 , G01N1/14 , G01N1/18 , G01N35/10 , G01N35/1016 , B01L2200/143 , B01L2200/148 , B01L2400/043 , B01L2400/049 , B01L2400/0487 , B01L2400/06 , B01L2400/0666 , G01N2001/1418 , G01N2035/1027
摘要： Automated pipetting systems and methods are disclosed for aspirating and dispensing fluids, particularly biological samples. In one aspect, a liquid dispenser includes a manifold and one or more pipette channels. The manifold includes a vacuum channel, a pressure channel, and a plurality of lanes. Each lane includes an electrical connector, a port to the pressure channel, and a port to the vacuum channel. The pipette channels can be modular. Each pipette channel includes a single dispense head and can be selectively and independently coupled to any one lane of the plurality of lanes. In some aspects, a valve in the pipette channel is in simultaneous fluid communication with a pressure port and a vacuum port of the manifold. The valve selectively diverts gas under pressure and gas under vacuum to the dispense head in response to control signals received through the electrical connector of the manifold.
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16.发明申请公开(公告)号：US20180246134A1
公开(公告)日：2018-08-30
申请号：US15556987
申请日：2017-02-17
发明人： Stephen LaChance , Alyssa Shedlosky , Alexander Clark , Redeat Girma Alemu , Craig Bark , Steven Charles Rotundo , Michael T. Vansickler
CPC分类号： G01N35/1072 , B01L3/021 , B01L3/0275 , B01L3/50273 , B01L3/527 , B01L2200/143 , B01L2200/148 , B01L2400/043 , B01L2400/0487 , B01L2400/049 , B01L2400/0666 , G01N1/18 , G01N35/10 , G01N2035/1027
摘要： Automated pipetting systems and methods are disclosed for aspirating and dispensing fluids, particularly biological samples. In one aspect, a liquid dispenser includes a manifold and one or more pipette channels. The manifold includes a vacuum channel, a pressure channel, and a plurality of lanes. Each lane includes an electrical connector, a port to the pressure channel, and a port to the vacuum channel. The pipette channels can be modular. Each pipette channel includes a single dispense head and can be selectively and independently coupled to any one lane of the plurality of lanes. In some aspects, a valve in the pipette channel is in simultaneous fluid communication with a pressure port and a vacuum port of the manifold. The valve selectively diverts gas under pressure and gas under vacuum to the dispense head in response to control signals received through the electrical connector of the manifold.
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17.发明申请公开(公告)号：US20180243735A1
公开(公告)日：2018-08-30
申请号：US15903767
申请日：2018-02-23
发明人： John D. Mantlo , Tong Zhou
CPC分类号： B01L3/021 , B01L3/0275 , B01L2300/0627 , B01L2300/069 , B01L2400/0487 , C12Q1/24 , G01N1/12 , G01N35/00584 , G01N35/0099 , G01N35/10 , G01N2001/028 , G01N2035/1027 , G01N2035/103
摘要： The present disclosure describes pipette tips haying an absorbent material (e.g., a flocking material) anchored to a distal end of the pipette tip and related methods of use. In some embodiments, the flocked pipette tips can be used in an automated process and/or system, wherein the contact between the pipette tips and either a sample or a culture medium can be automatically sensed for accurate sample collection and/or dispense. In some embodiments, automatic detection of the liquid interface may be accomplished by detecting a threshold change in capacitance when the pipette tip contacts the sample liquid interface (e.g., for sample collection) or the agar interface (e.g., for sample release). In some embodiments, the automated process and/or system may utilize one or more predetermined, fixed heights for collecting samples and/or depositing samples.
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