-
191.发明公开公开(公告)号：US20240281934A1
公开(公告)日：2024-08-22
申请号：US18681197
申请日：2022-08-31
Inventor： Yong Chan KIM
CPC classification number: G06T5/50 , A61B3/0025 , G06T7/0012 , G06T2207/10088 , G06T2207/10101 , G06T2207/30041
Abstract: A method for three-dimensionally modeling an eyeball and optical nerves using the merging of MRI images and OCT images, comprises: (a) a step for three-dimensionally modeling an eyeball model on the basis of the shapes of an eyeballs in a first MRI head image and a second MRI head image; (b) a step for three-dimensionally modeling an ASCO model in a corrected OCT eyeball cross-sectional image; (c) a step for three-dimensionally modeling the lamina cribrosa in the corrected OCT eyeball image; and (d) a step for generating an optic nerve model by three-dimensionally modeling an optic tract connected to the three-dimensionally modeled eyeball model.
-
公开(公告)号：US20240277775A1
公开(公告)日：2024-08-22
申请号：US18569023
申请日：2021-06-14
Applicant: VIGENCELL INC. , THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor： Hyun Jung SOHN , Tai Gyu KIM , Su Eon KIM , Soo Hyun JUNG , Hyun ll CHO , Bang Geul LIM , Eun Ah KIM
CPC classification number: A61K35/51 , A61P9/10 , C12N5/0634 , C12N2501/125 , C12N2501/22
Abstract: The present invention relates to the pharmaceutical use of a cord blood immunosuppressive cell and, more specifically, the present invention provides the use of a human-derived cord blood immunosuppressive cell, which is selected in accordance with analysis of function and phenotype and a classification standard, as a new cell therapy product for anti-inflammation, anti-fibrosis, and prevention or treatment of myocardial infarction.
-
193.发明公开公开(公告)号：US20240218368A1
公开(公告)日：2024-07-04
申请号：US18558075
申请日：2022-03-04
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , MYONGJI HOSPITAL
Inventor： Say June KIM , Ok Hee KIM , Min Ki KIM
CPC classification number: C12N15/1135 , A61K9/5063 , A61K9/5192 , A61P35/00 , C12N5/0653 , C12N15/85 , C12N2310/14
Abstract: The present invention relates to: a pharmaceutical composition comprising extracellular vesicles transformed with a recombinant expression vector in which a gene expressing a ligand that binds to receptors of colorectal cancer cells is inserted into a gene that is expressed in extracellular vesicles of stem cells; and a method for preparing an expression vector for preventing or treating colorectal cancer. The present invention has an advantage in that exosomes, as extracellular vesicles, can be utilized as a drug delivery material and target and specifically act on colorectal cancer by selectively binding to colorectal cancer cells which are target cells.
-
公开(公告)号：US12026878B2
公开(公告)日：2024-07-02
申请号：US17483711
申请日：2021-09-23
Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION , KONKUK UNIVERSITY GLOCAL INDUSTRY-ACADEMIC COLLABORATION FOUNDATION
Inventor： Jin Tae Kwak , Nhat To Minh Nguyen , Hyun Jeong Kim , Hong Gee Roh
CPC classification number: G06T7/0012 , A61B6/501 , G06T2207/10088 , G06T2207/20081 , G06T2207/30016
Abstract: A learning method for generating a multiphase collateral image comprises the steps of: receiving inputs of an MRI image of a head part and a multiphase collateral image generated on the basis of the MRI image; generating a brain mask by using the MRI image; generating an MRI image and a multiphase collateral image which are masked by the brain mask; and learning the masked multiphase collateral image for the masked MRI image by using a learning network.
-
公开(公告)号：US20240207457A1
公开(公告)日：2024-06-27
申请号：US18288667
申请日：2022-05-10
Inventor： Jae Myung PARK , Moon Hwa KWAK
CPC classification number: A61K51/08 , A61K41/0061 , A61K41/0071 , A61K41/0076 , A61K49/0056 , A61P35/00
Abstract: An aspect relates to a cancer-specific polypeptide consisting of an amino acid sequence of SEQ ID NO: 1. The polypeptide according to an aspect may bind specifically to LGR5 protein expressed in a tumor tissue, and when binding to a labeling material (for example, a fluorescent material), a cancer that expresses the LGR5 protein may be diagnosed. Furthermore, when the polypeptide binds to an isotope, a metastatic tumor may be also diagnosed. When the polypeptide according to an aspect binds to a photosensitizer and is then administered to a subject, the photosensitizer may be activated through light irradiation so that cancer cells may be killed, thereby enabling the prevention, amelioration, or treatment of cancer.
-
Patent Agency Ranking
公开(公告)号：US20240115132A1
公开(公告)日：2024-04-11
申请号：US18481952
申请日：2023-10-05
Inventor： Hosik Hwang
Abstract: A slit lamp microscope may include first and second arms rotatably provided on a main shaft; a microscope provided on the first arm and used to observe a subject's eyeball; a light source unit provided on the second arm and irradiating light including near-ultraviolet and visible light regions, including light with a wavelength of 405 nm, to the eyeball of a subject; a third arm rotatably provided on the main shaft; a camera provided on the main shaft and imaging the eyeball of the subject; an excitation filter that transmits only light with a wavelength of 405 nm that induces a fluorescence reaction in stained goblet cells among the light irradiated from the light source unit to the eyeball of the subject; and a light receiving filter that transmits only the light fluorescently reacted in the goblet cells among the light received by the camera.
-
公开(公告)号：US11925726B2
公开(公告)日：2024-03-12
申请号：US17126449
申请日：2020-12-18
Applicant: POSTECH Research and Business Development Foundation , THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventor： Dong-Woo Cho , Wonil Han , Narendra K. Singh , Yong Kyun Kim , Sun Ah Nam
CPC classification number: A61L27/3839 , A61F2/022 , A61L27/3641 , A61L27/3683 , A61L27/3886 , C12N5/0685 , C12N5/0686 , C12N5/069 , C12N5/0697
Abstract: The present disclosure is related to a perfusable-type bio-dual proximal tubule cell construct and a producing method thereof capable of applying an in vitro artificial organ model configured to include a first bioink comprising a decellularized substance derived from a mammalian kidney tissue and human umbilical vascular endothelial cells (HUVECs) and a second bioink comprising the decellularized substance and renal proximal tubular epithelial cells (RPTECs), wherein the first bioink and the second bioink are coaxial and printed in tubular constructs having different inner diameters.
According to the present disclosure, it is possible to use the renal proximal tubule-on-a-chip as a bioreactor capable of observing a biological drug reaction similar to a real drug by perfusing various drugs to the renal proximal tubule-on-a-chip.-
公开(公告)号：US20240021096A1
公开(公告)日：2024-01-18
申请号：US18251840
申请日：2021-10-22
Inventor： Sun IM , Cheol Ki KIM
CPC classification number: G09B5/02 , A61B5/4803
Abstract: Provided are a self voice training method for a patient with a voice disorder and a user terminal for self voice training. The user terminal for self voice training includes an input device configured to receive a training program selection command of a user, a storage configured to store voice training candidate programs for the user's voice training, a calculator configured to generate first guide content according to a first voice training program selected from among the voice training candidate programs by the user, an output device configured to output the first guide content, and a microphone configured to receive voice output by the user according to the first guide content output through the output device.
-
公开(公告)号：US11857237B2
公开(公告)日：2024-01-02
申请号：US17424750
申请日：2019-12-23
Inventor： Seung Han Shin , Yang Guk Chung , Do Kun Yoon , Moo Sub Kim
CPC classification number: A61B17/8866 , A61B17/808
Abstract: Provided is forceps for internal fixation, including: a first member having a first holding portion for holding a first side of bone fragments and a first grip extending from the first holding portion; and a second member having a second holding portion for holding a second side spaced a predetermined distance from the first side of the bone fragments and a second grip extending from the second holding portion.
-
200.发明公开公开(公告)号：US20230289966A1
公开(公告)日：2023-09-14
申请号：US18319981
申请日：2023-05-18
Inventor： Youn Jin CHOI , Soo-Young HUR , Heekyoung SONG , Jaeyoung MIN
CPC classification number: G06T7/0012 , G06T7/60 , G06T2207/30096 , G06T2207/20081 , G06T2207/10068
Abstract: A method of generating excision tool information using a cervicography image includes receiving, by an analysis apparatus, a cervicography image of a patient, inputting, by the analysis apparatus, the cervicography image to a learning model to detect a lesion area, additionally setting, by the analysis apparatus, a margin area based on the lesion area to determine an excision area, and selecting, by the analysis apparatus, one excision tool according to a shape and size of the excision area, or generating a source model for manufacturing an excision tool based on the shape and size of the excision area.
-
-
-
-
-
-
-
-
-
Search Results
324
records
(took 0.028 seconds)
